Read by QxMD icon Read

Slipped disc

Nam Lee, Gyu Yeul Ji, Seong Yi, Do Heum Yoon, Dong Ah Shin, Keung Nyun Kim, Yoon Ha, Chang Hyun Oh
BACKGROUND: It is well documented that epidural adhesion is associated with spinal pain. However, the underlying mechanism of spinal pain generation by epidural adhesion has not yet been elucidated. OBJECTIVES: To elucidate the underlying mechanism of spinal pain generation by epidural adhesion using a two-dimensional (2D) non-linear finite element (FE) analysis. STUDY DESIGN: A finite element analysis. SETTING: A two-dimensional nonlinear FE model of the herniated lumbar disc on L4/5 with epidural adhesion...
July 2016: Pain Physician
Saher Abu-Leil, Yizhar Floman, Yigal Bronstein, Youssef Masharawi
PURPOSE: Most morphometric studies on lumbar degenerative spondylolisthesis (DS) have focused solely on the L4-L5 slipped level, neglecting the shape of the entire lumbar segments. The purpose of this study was to present a morphometric analysis of the entire lumbar IVDs and VBs in DS. METHODS: Out of 500 lumbar CTs, the first 100 CTs, 50 with DS at L4 and 50 age- and sex-matched control CTs, were randomly selected. All lumbar IVD and VB heights, widths, lengths and sagittal wedging as well as lumbar lordosis (LL) and sacral inclination (SI) were measured and relevant ratios calculated...
August 2016: European Spine Journal
Gregory D Schroeder, Cynthia R LaBella, Marco Mendoza, Erika L Daley, Jason W Savage, Alpesh A Patel, Wellington K Hsu
PURPOSE: To determine if adolescent athletics increases the risk of structural abnormalities in the lumbar spine. METHODS: A retrospective review of patients (ages 10-18) between 2004 and 2012 was performed. Pediatric patients with symptomatic low back pain, a lumbar spine MRI, and reported weekly athletic activity were included. Patients were stratified to an "athlete" and "non-athlete" group. Lumbar magnetic resonance and plain radiographic imaging was randomized, blinded, and evaluated by two authors for a Pfirrmann grade, herniated disc, and/or pars fracture...
September 2016: European Spine Journal
Shiro Imagama, Noriaki Kawakami, Tokumi Kanemura, Yuji Matsubara, Taichi Tsuji, Tetsuya Ohara, Yoshito Katayama, Naoki Ishiguro
STUDY DESIGN: Retrospective clinical study. OBJECTIVE: To investigate adjacent segment degeneration (ASD) at 5 years after L4/5 posterior lumbar interbody fusion (PLIF) with pedicle screw instrumentation and L4/5 decompression surgery using plain radiographs, CT and MRI, with evaluation of annual changes on MRI. SUMMARY OF BACKGROUND DATA: Methods of evaluation have been inconsistent among studies of ASD. There is no report that ASD in the lumbar spine after PLIF at the same level is thoroughly evaluated on radiographs, CT, annual MRI changes, and the impact of decompression procedures...
May 2, 2016: Clinical Spine Surgery
Hubertine Marjoleine Willems, Kevin Kos, Mary Ann Jabra-Rizk, Bastiaan P Krom
Streptococcus mutans is a Gram-positive bacterium involved in development to caries, the most common infectious disease of our time. Streptococcus mutans interacts with other microbes, like the fungus Candida albicans and both are commonly isolated from patients with caries. Since the role of C. albicans in caries remains unknown, our aim was to unravel this using an in vitro dual-species cariogenic oral biofilm model. Biofilms were grown for 24-72 h on glass cover slips or hydroxyapatite (HA) disks to mimic the surface of teeth...
July 2016: Pathogens and Disease
Ujjwal K Debnath, Atanu Chatterjee, Jeffrey R McConnell, Deepak K Jha, Tapas Chakraburtty
STUDY DESIGN: Prospective nonrandomized study. PURPOSE: To find a possible correlation between clinical outcome and extent of lumbar spondylolisthesis reduction. OVERVIEW OF LITERATURE: There is no consensus in the literature concerning whether a beneficial effect of reduction on outcome can be expected following reduction and surgical fusion for low grade lumbar spondylolisthesis. METHODS: Forty six patients with a mean age of 37...
April 2016: Asian Spine Journal
Claudio Vergari, Jessica Mansfield, Judith R Meakin, Peter C Winlove
UNLABELLED: The intervertebral disc is a multicomposite structure, with an outer fibrous ring, the annulus fibrosus, retaining a gel-like core, the nucleus pulposus. The disc presents complex mechanical behaviour, and it is of high importance for spine biomechanics. Advances in multiscale modelling and disc repair raised a need for new quantitative data on the finest details of annulus fibrosus mechanics. In this work we explored inter-lamella and inter-bundle behaviour of the outer annulus using micromechanical testing and second harmonic generation microscopy...
June 2016: Acta Biomaterialia
Antoine Nachanakian, Antonios El Helou, Moussa Alaywan
INTRODUCTION: Managements of lumbar stenosis evoluted over the time from decompression to dynamic stabilization preserving the motion segment passing by the rigid fixation. After long years of rigid fusion, adjacent segment disease became more and more frequent and the concept of dynamic stabilization emerged. MATERIALS AND METHODS: We report our experience with posterior dynamic stabilization using an interspinous distracter (ISD). One hundred and eight patients were operated between September 2008 and January 2012 with different lumbar spine pathologies...
April 2016: Asian Journal of Neurosurgery
Savitri Nilakanthan, Kashinath Metri, Nagaratna Raghuram, Nagendra Hongasandra
BACKGROUND: A significant number of women in India are suffering from hypothyroidism. Hypothyroidism is characterized by elevated lipid profiles and thyroid stimulation hormone (TSH). It leads many comorbid conditions such as coronary artery disease, obesity, depression, osteoporosis, sleep apnea, and etc. Yoga is proven to be effective in reducing weight, dyslipidemia, depression and it brings the balance in autonomous nervous system. We aimed to study the effect of 6 months yoga practice on lipid profile, thyroxine requirement and serum TSH in women suffering from hypothyroidism...
June 1, 2016: Journal of Complementary & Integrative Medicine
Shugo Kuraishi, Jun Takahashi, Keijiro Mukaiyama, Masayuki Shimizu, Shota Ikegami, Toshimasa Futatsugi, Hiroki Hirabayashi, Nobuhide Ogihara, Hiroyuki Hashidate, Yutaka Tateiwa, Hisatoshi Kinoshita, Hiroyuki Kato
STUDY DESIGN: Multicenter analysis of two groups of patients surgically treated for degenerative L4 unstable spondylolisthesis. PURPOSE: To compare the clinical and radiographic outcomes of posterolateral fusion (PLF) and posterior lumbar interbody fusion (PLIF) for degenerative L4 unstable spondylolisthesis. OVERVIEW OF LITERATURE: Surgery for lumbar degenerative spondylolisthesis is widely performed. However, few reports have compared the outcome of PLF to that of PLIF for degenerative L4 unstable spondylolisthesis...
February 2016: Asian Spine Journal
Jason Pui Yin Cheung, Prudence Wing Hang Cheung, Kenneth Man Chee Cheung, Keith Dip Kei Luk
STUDY DESIGN: Retrospective series. PURPOSE: Assess results of decompression-only surgery for low-grade degenerative spondylolisthesis with consideration of instability. OVERVIEW OF LITERATURE: There is no consensus on whether fusion or decompression-only surgery leads to better outcomes for patients with low-grade degenerative spondylolisthesis. Current trends support fusion but many studies are flawed due to over-generalization without consideration of radiological instability and their variable presentations and natural history...
February 2016: Asian Spine Journal
Se Ho Jeong, Hyeun Sung Kim, Seok Won Kim
OBJECTIVE: The purpose of this study was to evaluate the surgical technique and outcome of mini-open posterior lumbar interbody fusion (PLIF) under circumferential releasing technique. METHODS: Fourty patients who underwent mini-open PLIF using the percutaneous screw fixation system for Meyerding Grade II spondylolisthesis or more were retrospectively studied. After complete circumferential release, the slipped vertebrae would tend to obtain spontaneous reduction, and with compressive force by percutaneous screw fixation, additional reduction could be achieved...
December 2015: Korean Journal of Spine
Daniel M Skrzypiec, Katrin Nagel, Kay Sellenschloh, Anke Klein, Klaus Püschel, Michael M Morlock, Gerd Huber
An in-vitro experiment was designed to investigate the mode of failure following shear fatigue loading of lumbar motion-segments. Human male lumbar motion-segments (age 32-42 years, n=6) were immersed in Ringer solution at 37°C and repeatedly loaded, using a modified materials testing machine. Fatigue loading consisted of a sinusoidal shear load from 0 N to 1,500 N (750 N±750 N) applied to the upper vertebra of the motion-segment, at a frequency of 5 Hz. During fatigue experiments, several failure events were observed in the dynamic creep curves...
August 5, 2016: Industrial Health
Gen Mori, Yasuo Mikami, Yuji Arai, Takumi Ikeda, Masateru Nagae, Hitoshi Tonomura, Ryota Takatori, Koshiro Sawada, Hiroyoshi Fujiwara, Toshikazu Kubo
OBJECT: There are reports that fusion is the standard treatment of choice for cases of lumbar degenerative spondylolisthesis (LDS) associated with lumbar spinal canal stenosis with a large degree of slippage. The reasons why, however, have not been clarified. On the other hand, it is known that the progress of slippage decreases and restabilization occurs over the natural course of LDS. Therefore, if minimally invasive decompression could be performed, there would be little possibility of it influencing the natural course of LDS, so it would not be necessary to include preoperative percentage slip in the criteria for the selection of fusion...
March 2016: Journal of Neurosurgery. Spine
Shannon Fischer
Opportunities for gathering vital information on cancer, heart disease, and other complicated diseases via clinical models are missed despite the at least 70 million pet dogs and 74 million pet cats in the United States alone that experience these very illnesses. This article presents a general discussion on the current state and hindrances to comparative medicine.
September 2015: IEEE Pulse
Xiaokang Liu, Yingjie Liu, Xiaofeng Lian, Jianguang Xu
The aim of the study was to investigate the changes of the lumbar intervertebral disc degeneration by magnetic resonance imaging (MRI) after the implantation of interspinous device and the fusion of the adjacent segment. A total of 62 consecutive patients suffering L5/S1 lumbar disc herniation (LDH) with concomitant disc space narrowing or low-grade instability up to 5 mm translational slip in L5/S1 level were treated with lumbar interbody fusion (LIF) via posterior approach. Thirty-four of these patients (Coflex group) received an additional implantation of the interspinous spacer device (Coflex™) in the level L4/L5, while the rest of 28 patients (fusion group) underwent the fusion surgery alone...
2015: International Journal of Clinical and Experimental Medicine
Jong Yeol Kim, Jeong Yoon Park, Kyung Hyun Kim, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho
INTRODUCTION: Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) is a common surgical option for degenerative spondylolisthesis (DS). However, its effectiveness for isthmic spondylolisthesis (IS) is still controversial. No current studies have directly compared perioperative and postoperative results including various radiological parameters between IS and DS after MIS TLIF. PURPOSE: The purpose of this study is to compare the clinical and radiological results between isthmic and degenerative spondylolisthesis after MIS TLIF...
November 2015: World Neurosurgery
Jens Höfflin, Saraí M Torres Delgado, Fralett Suárez Sandoval, Jan G Korvink, Dario Mager
We present a design for wireless power transfer, via inductively coupled coils, to a spinning disk. The rectified and stabilised power feeds an Arduino-compatible microcontroller (μC) on the disc, which in turn drives and monitors various sensors and actuators. The platform, which has been conceived to flexibly prototype such systems, demonstrates the feasibility of a wireless power supply and the use of a μC circuit, for example for Lab-on-a-disk applications, thereby eliminating the need for cumbersome slip rings or batteries, and adding a cogent and new degree of freedom to the setup...
June 21, 2015: Lab on a Chip
Hiroaki Nakashima, Noriaki Kawakami, Taichi Tsuji, Tetsuya Ohara, Yoshitaka Suzuki, Toshiki Saito, Ayato Nohara, Ryoji Tauchi, Kyotaro Ohta, Nobuyuki Hamajima, Shiro Imagama
STUDY DESIGN: Retrospective case-controlled study. OBJECTIVE: To investigate the incidence of adjacent segment degeneration (ASD) and the associated risk factors during a period of at least 10 years after posterior lumbar interbody fusion (PLIF). SUMMARY OF BACKGROUND DATA: ASD is a problematic sequelae after spinal fusion surgery. Few long-term follow-up studies have investigated ASD after PLIF; thus, magnetic resonance imaging (MRI) data available for the evaluation of postoperative changes associated with ASD are limited...
July 15, 2015: Spine
Wei Tian, Xiao-Guang Han, Bo Liu, Ya-Jun Liu, Da He, Qiang Yuan, Yun-Feng Xu
BACKGROUND: The treatment of high-grade developmental spondylolisthesis (HGDS) is still challenging and controversial. In this study, we investigated the efficacy of the posterior reduction and monosegmental fusion assisted by intraoperative three-dimensional (3D) navigation system in managing the HGDS. METHODS: Thirteen consecutive HGDS patients were treated with posterior decompression, reduction and monosegmental fusion of L5/S1, assisted by intraoperative 3D navigation system...
April 5, 2015: Chinese Medical Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"