keyword
https://read.qxmd.com/read/38304575/role-of-epac1-in-chronic-pain
#1
REVIEW
Chenlu Jiang, Jiacheng Zhao, Yihang Zhang, Xiang Zhu
Chronic pain usually lasts over three months and commonly occurs in chronic diseases (cancer, arthritis, and diabetes), injuries (herniated discs, torn ligaments), and many major pain disorders (neuropathic pain, fibromyalgia, chronic headaches). Unfortunately, there is currently a lack of effective treatments to help people with chronic pain to achieve complete relief. Therefore,it is particularly important to understand the mechanism of chronic pain and find new therapeutic targets. The exchange protein directly activated by cyclic adenosine monophosphate(cAMP) (EPAC) has been recognized for its functions in nerve regeneration, stimulating insulin release, controlling vascular pressure, and controlling other metabolic activities...
March 2024: Biochemistry and Biophysics Reports
https://read.qxmd.com/read/37774782/cervical-conjoined-nerve-root-during-posterior-percutaneous-endoscopic-cervical-discectomy
#2
Mei-Cheng Hsiao, Kai-Chen Chung, Hsi-Kai Tsou, Yu-Hao Chang, Ting-Hsien Kao, Chun-Pi Chang
Cervical conjoined nerve root is rare, and medical imaging, such as MRI and CT, cannot give an accurate preoperative diagnosis.1 Treatment of cervical radiculopathy with root anomaly can be challenging. We report here a case of cervical conjoined nerve root with 2-dimensional video. A 41-year-old woman without systemic disease presented with a 2-months' history of neck and bilateral shoulder pain, upper back tightness, and left upper limb painful numbness, especially of the 1st to 3rd fingers. The visual analogue scale (VAS) of the neck and left upper limb were 4 and 8, respectively...
September 27, 2023: World Neurosurgery
https://read.qxmd.com/read/37774180/clinical-effectiveness-of-posterior-annular-targeted-ablative-decompression-as-an-alleviative-intervention-for-lumbosacral-discogenic-pain-systematic-review-and-meta-analysis
#3
JOURNAL ARTICLE
Jung Hwan Lee, Youn Joo Lee, Hahck Soo Park, Jun Ho Lee
BACKGROUND: Various percutaneous intradiscal procedures have been implemented to manage lumbosacral discogenic pain. But most of these procedures simply end up manipulating the central nucleus pulposus or the inner annulus, instead of accessing the posterior outer annulus where the actual, major pain generators exist. Thus, more localized percutaneous techniques, specifically derived to address the pathologic tissues creeped between the torn, posterior annulus and hyperplastic sinuvertebral nerve, have been devised...
September 2023: Pain Physician
https://read.qxmd.com/read/37211932/-comparison-of-clinical-effect-and-muscle-injury-imaging-between-oblique-lateral-lumbar-interbody-fusion-and-transforaminal-lumbar-interbody-fusion-in-the-treatment-of-single-segment-degenerative-lumbar-spinal-stenosis
#4
JOURNAL ARTICLE
San-Biao Li, Sheng-Qian Mei, Wen-Bin Xu, Xiang-Qian Fang, Shun-Wu Fan, Li-Bin Huang
OBJECTIVE: To compare the efficacy and muscle injury imaging between oblique lateral lumbar interbody fusion (OLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of single-segment degenerative lumbar spinal stenosis. METHODS: The clinical data of 60 patients with single-segment degenerative lumbar spinal stenosis who underwent surgical treatment from January 2018 to October 2019 was retrospectively analyzed. The patients were divided into OLIF groups and TLIF group according to different surgical methods...
May 25, 2023: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/36800670/results-of-a-shuttle-catheter-technique-for-surgical-repair-of-acute-extensor-hallucis-longus-tears
#5
JOURNAL ARTICLE
Osama Samir Gaarour, Amr Elshahhat
BACKGROUND AND STUDY AIMS: The proximal end of a torn Extensor hallucis longus (EHL) is usually so retracted that a proximal wound extension is always required to retrieve it; leading to more adhesions and stiffness. This study aims at assessment of a novel technique for proximal stump retrieval and repair of acute EHL injuries with no need for wound extension. MATERIAL AND METHODS: Thirteen patients with acute EHL tendon injuries at zones III, IV were prospectively included in our series...
December 2022: Acta Orthopaedica Belgica
https://read.qxmd.com/read/34774665/creation-of-3d-anatomical-models-illustrating-an-intact-and-centrally-torn-triangular-fibrocartilage-complex-for-patient-education-prior-treatment
#6
JOURNAL ARTICLE
Eleni Patera, Philippa Ann Rust
BACKGROUND: The triangular fibrocartilage complex (TFCC) is a composite structure located in the human wrist and is made up from fibrocartilage and ligaments. It consists of eight distinct structures, with the ligamentous structures acting as the major stabilizer of the distal radioulnar joint and with the articular disc acting as a shock absorber at the ulnocarpal joint. The articular disc can be called the triangular fibrocartilage (TFC). Thus, traumatic injuries of the TFCC ligamentous structures cause instability of the joint and a centrally torn TFC disc causes ulnar sided wrist pain...
February 2022: Annals of Anatomy
https://read.qxmd.com/read/33728187/traumatic-spondylolisthesis-of-the-fourth-lumbar-vertebra-without-neurologic-deficit-or-fracture-of-the-posterior-elements
#7
Ioannis Papaioannou, Thomas Repantis, Georgia Pantazidou, Andreas Baikousis, Panagiotis Korovessis
Acute traumatic spondylolisthesis in the lumbosacral spine is an uncommon injury. Traumatic dislocation of the fourth lumbar vertebra over the fifth lumbar vertebra (L4/L5) is extremely rare since few studies have been reported in the current literature. We report on a 53-year-old man, who had a motor vehicle accident and sustained an injury of the lumbar spine without neurological impairment. The radiographic evaluation disclosed an L4/L5 traumatic spondylolisthesis, classified as Meyerding grade III without any fracture of the posterior vertebral elements...
February 9, 2021: Curēus
https://read.qxmd.com/read/33157322/analysis-of-the-influence-of-species-intervertebral-disc-height-and-pfirrmann-classification-on-failure-load-of-an-injured-disc-using-a-novel-disc-herniation-model
#8
JOURNAL ARTICLE
Sohrab Virk, Kathleen N Meyers, Virginie Lafage, Suzanne A Maher, Tony Chen
BACKGROUND CONTEXT: Annular repair devices offer a solution to recurrent disc herniations by closing an annular defect and lowering the risk of reherniation. Given the significant risk of neurologic injury from device failure it is imperative that a reliable preclinical model exists to demonstrate a high load to failure for the disc repair devices. PURPOSE: To establish a preclinical model for disc herniation and demonstrate how changes in species, intervertebral disc height and Pfirrmann classification impacts failure load on an injured disc...
April 2021: Spine Journal: Official Journal of the North American Spine Society
https://read.qxmd.com/read/31295006/evaluation-of-the-triangular-fibrocartilage-comparison-of-two-compartment-wrist-ct-arthrography-using-the-distal-radioulnar-and-adiocarpal-joints-and-uni-compartment-wrist-ct-arthrography-using-the-radiocarpal-joint
#9
JOURNAL ARTICLE
Sujin Kim, Guen Young Lee, Jae Sung Lee
OBJECTIVE: To compare the diagnostic performance of two-compartment wrist CT arthrography of the distal radioulnar and radiocarpal joints and uni-compartment wrist CT arthrography of radiocarpal joint in depiction of the triangular fibrocartilage tear. METHODS: From Jan. 2016 to Dec. 2017, two-compartment CT arthrography of 74 consecutive patients (36 females, 38 males; mean age, 37.2 years) and uni-compartment CT arthrography of 51 consecutive patients (18 females, 33 males; mean age, 40...
July 11, 2019: British Journal of Radiology
https://read.qxmd.com/read/30921984/using-percutaneous-endoscopic-outside-in-technique-to-treat-selected-patients-with-refractory-discogenic-low-back-pain
#10
JOURNAL ARTICLE
Keng-Chang Liu, Shyi-Kuen Yang, Bor-Rung Ou, Min-Hong Hsieh, Chih-En Tseng, Chia-Wei Chang, Shih-Hao Chen
BACKGROUND: Controversy is not uncommon in the diagnosis of discogenic low back pain (DLBP) and in the identification of the location of the pain source for the symptomatic disc in patients with DLBP. Various techniques, from minimally invasive procedures to fusion surgery, are used to treat chronic DLBP, but the clinical outcomes are variable. Percutaneous endoscopic discectomy by transforaminal or interlaminar approach is considered to be an effective method to treat DLBP, but the evidence is limited; the lack of clear evidence may be associated with patient selection and surgical technique...
March 2019: Pain Physician
https://read.qxmd.com/read/30893987/femoral-avulsion-of-the-anterior-cruciate-ligament-in-a-multiligament-setting-a-unique-case
#11
JOURNAL ARTICLE
Vikram Arun Mhaskar, Jitendra Mahehswari, Manjeet Sansanwal
Anterior cruciate ligament (ACL) femoral avulsions are a rare entity mainly seen in children. We describe a unique case of a bony ACL avulsion with a medial collateral ligament (MCL) and lateral meniscus (LM) tear in a 37-year-old patient who sustained a two-wheeler accident. The ACL femoral avulsion was fixed arthroscopically using a Knee Scorpion and a FiberTape fixed over a suture disc on the lateral cortex. The MCL was repaired with an internal brace using a FiberTape and two SwiveLocks and the torn LM was repaired using all-inside sutures...
June 1, 2019: Knee Surgery & related Research
https://read.qxmd.com/read/30767026/-rare-case-of-palmar-disc-dislocation-after-wrist-distorsion
#12
JOURNAL ARTICLE
Christopher Kloth, Till Fischborn, Heike Preibsch, Jörg Schmehl
OBJECTIVE: The aim of this study was the elaboration of clinical symptoms and image findings in injuries of the wrist and ulnar-sided pain with accompanying damage to the articular disc and the triangular fibrocartilage complex (TFCC). MATERIAL AND METHODS: This article reports about a 26-year-old male patient who presented to the department of surgery of this hospital after repeated falls onto the right wrist. Following the latest fall there was persistent wrist pain and limited movement, especially in supination...
February 14, 2019: Der Unfallchirurg
https://read.qxmd.com/read/28358780/the-cure-that-lies-within-the-mind-body-connection-in-orthopaedics
#13
JOURNAL ARTICLE
Erin Sullivan, Jeremy Hudson
The mind and the body are clearly intertwined in ways that are only now being discovered. In the orthopaedic world, injuries and diseases are often classified and described in a very organized, discrete fashion-The radius is fractured, the ACL or meniscus or rotator cuff is torn, the ankle is sprained, and/or the lumbar spine has a disc herniation. Although it is, in many ways, almost comforting to think about injuries or orthopaedic issues in this manner, what about the many patients who fail to fall into this classification? What about the thousands of patients with severe unexplained chronic pain or patients who just are not improving with the typical treatment algorithm...
2017: Orthopaedic Nursing
https://read.qxmd.com/read/28164061/arthroscopic-meniscectomy-and-meniscoplasty-for-a-torn-discoid-medial-meniscus-case-report-surgical-technique-and-literature-review
#14
JOURNAL ARTICLE
Gokhale Nikhil Abhay, Samant Ashwin, Shahane Sunil, Kapopara Hardik
INTRODUCTION: Normal menisci of the knee are semilunar structures. Sometimes, a meniscus may be found to be thickened and disc like and is called a discoid meniscus. Such a discoid variant is usually found in the lateral meniscus. Its occurrence in the medial meniscus is extremely rare. CASE REPORT: We report a case of an 18-year-old female, who presented to us with knee pain and was found to have a discoid medial meniscus with a tear. We operated on her arthroscopically and performed meniscectomy and meniscoplasty...
September 2016: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/27614964/invagination-of-intra-abdominal-structures-in-the-lumbar-intervertebral-disc-space
#15
JOURNAL ARTICLE
Ji Na Kim, Soon Tae Kwon, Kyung Nam Ryu
Invagination of peritoneal or retroperitoneal structures into the intervertebral disc space of the lumbar spine is extremely rare. In this article the imaging features and clinical findings are demonstrated in four patients with intervertebral invagination of intra-abdominal structures. Plain radiographs, CT scans, and MR images showed disruption of the anterior ligamentous complex (ALC) and invagination of various structures into the disc space, including the vena cava, iliac vessels, intestine, the torn redundant anterior longitudinal ligament, retroperitoneal fat, and the psoas muscle...
November 2016: Skeletal Radiology
https://read.qxmd.com/read/26911974/what-are-the-functional-outcomes-after-total-sacrectomy-without-spinopelvic-reconstruction
#16
JOURNAL ARTICLE
Piya Kiatisevi, Chaiwat Piyaskulkaew, Sombat Kunakornsawat, Bhasanan Sukunthanak
BACKGROUND: After total sacrectomy, many types of spinopelvic reconstruction have been described with good functional results. However, complications associated with reconstruction are not uncommon and usually result in further surgical interventions. Moreover, less is known about patient function after total sacrectomy without spinopelvic reconstruction, which may be indicated when malignant or aggressive benign bone and soft tissue tumors involved the entire sacrum. QUESTIONS/PURPOSES: (1) What is the functional outcome and ambulatory status of patients after total sacrectomy without spinopelvic reconstruction? (2) What is the walking ability and ambulatory status of patients when categorized by the location of the iliosacral resection relative to the sacroiliac joint? (3) What complications and reoperations occur after this procedure? METHODS: Between 2008 and 2014, we performed 16 total sacrectomies without spinopelvic reconstructions for nonmetastatic oncologic indications...
March 2017: Clinical Orthopaedics and related Research
https://read.qxmd.com/read/26071947/complete-fracture-of-the-lamina-of-the-sixth-cervical-vertebra-with-hemiplegia-a-case-report
#17
JOURNAL ARTICLE
Anouar Bourghli, Clement Ribes, Ibrahim Obeid, Louis Boissiere, Jean-Marc Vital
INTRODUCTION: We report the rare case of a 27-year-old man who presented a right sided complete hemiplegia after a neck trauma due to a road traffic accident. MATERIALS AND METHODS: Computed tomography revealed a complete fracture of the C6 lamina including a partial fracture of the right articular process with complete rotation of the fragment into the spinal canal with a major compression of the right side of the cord. The patient was operated urgently and underwent posterior approach for C6 arch removal followed by a C6C7 anterior fusion as T2 weighted magnetic resonance imaging revealed a completely torn C6C7 disc with a hematoma under the posterior longitudinal ligament associated with an increased cord signal...
May 2016: European Spine Journal
https://read.qxmd.com/read/25606549/acromioclavicular-joint-instability-anatomy-biomechanics-and-evaluation
#18
JOURNAL ARTICLE
Maristella F Saccomanno, Carmine DE Ieso, Giuseppe Milano
Acromioclavicular (AC) joint instability is a common source of pain and disability. The injury is most commonly a result of a direct impact to the AC joint. The AC joint is surrounded by a capsule and has an intra-articular synovium and an articular cartilage interface. An articular disc is usually present in the joint, but this varies in size and shape. The AC joint capsule is quite thin, but has considerable ligamentous support; there are four AC ligaments: superior, inferior, anterior and posterior. The coracoclavicular (CC) ligament complex consists of the conoid and trapezoid ligaments...
2014: Joints
https://read.qxmd.com/read/25393059/effectiveness-of-a-new-navigable-percutaneous-disc-decompression-device-l-disq-in-patients-with-lumbar-discogenic-pain
#19
JOURNAL ARTICLE
Sang Heon Lee, Richard Derby, Donggeun Sul, Young Ki Hong, Kang Wook Ha, Dongwon Suh, Sang Hoon Lee, Hyung Suk Yoon, Seung Han Yoo, Seok Jun Lee, Hyeun Jun Park, Yong Jin Jung, Jeong Eun Lee, Nack Hwan Kim
OBJECTIVE: This study is a pilot study to assess the clinical outcomes of percutaneous disc decompression using the L'DISQ in patients with lumbar discogenic pain. STUDY DESIGN: An institutional, prospective clinical data analysis. METHODS: We ablated the torn annulus using L'DISQ on 20 patients with axial low back pain for at least 3 months (average 29 months) unresponsive to conservative management. Before the therapeutic procedure, all the patients had been diagnosed with lumbar discogenic pain through provocation discography, which had confirmed the level of painful discs...
February 2015: Pain Medicine
https://read.qxmd.com/read/24741142/acromioclavicular-joint-acceleration-deceleration-injury-as-a-cause-of-persistent-shoulder-pain-outcome-after-arthroscopic-resection
#20
JOURNAL ARTICLE
Ehud Atoun, Artan-Athanasios Bano, Alexander Van Tongel, Ali Narvani, Giuseppe Sforza, Ofer Levy
BACKGROUND: Shoulder pain in general and acromioclavicular joint (ACJ) pain specifically is common after acceleration-deceleration injury following road traffic accident (RTA). The outcome of surgical treatment in this condition is not described in the literature. The aim of the present study was to report the outcome of arthroscopic resection of the ACJ in these cases. MATERIALS AND METHODS: Nine patients with localized ACJ pain, resistant to nonoperative treatment were referred on an average 18 months after the injury...
March 2014: Indian Journal of Orthopaedics
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