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neonatal diabetes and gestational diabetes

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https://www.readbyqxmd.com/read/28547098/obstetrical-and-perinatal-morbidity-and-mortality-among-in-vitro-fertilization-pregnancies-a-population-based-study
#1
Hussein Sabban, Andrew Zakhari, Valerie Patenaude, Togas Tulandi, Haim A Abenhaim
PURPOSE: To compare patient characteristics and obstetrical/neonatal outcomes of in-vitro fertilization (IVF) and spontaneously conceived pregnancies. METHODS: Using the Nationwide Inpatient Sample, we conducted a retrospective cohort study from 2008 to 2011 comparing IVF conceptions to spontaneous ones. Patient characteristics were descriptively compared, and after adjusting for baseline characteristics with logistic regression, obstetrical/neonatal outcomes were also compared...
May 25, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28546666/comparison-of-one-step-versus-two-step-screening-for-diagnosis-of-gdm-in-indian-population-a-randomized-controlled-trial
#2
Mohit Satodiya, Navneet Takkar, Poonam Goel, Jasbinder Kaur
OBJECTIVE: To compare the incidence, maternal and fetal outcomes of gestational diabetes mellitus using one step versus two steps as a screening procedure. METHODOLOGY: A prospective randomized trial involving screening of 1000 pregnant women for gestational diabetes mellitus was conducted. Women were divided in two groups (500 each). Group A comprised of patients screened with two-step approach (ACOG recommendation), and group B comprised of women screened by one-step method (IADPSG criteria)...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28545656/cord-plasma-insulin-and-in-utero-exposure-to-ambient-air-pollution
#3
Narjes Madhloum, Bram G Janssen, Dries S Martens, Nelly D Saenen, Esmée Bijnens, Wilfried Gyselaers, Joris Penders, Charlotte Vanpoucke, Wouter Lefebvre, Michelle Plusquin, Tim S Nawrot
INTRODUCTION: Cardio-metabolic risk factors including insulin levels are at young age barely perceived as harmful, but over time these risk factors may track and lead to higher risk of metabolic syndrome. Studies showed that exposure to air pollution is associated with an increased risk of insulin resistance in childhood. We determined whether the origin of type 2 diabetes can be found in the early childhood by examining the levels of insulin in the neonatal cord blood and whether this can be considered as a disease marker for later life...
May 22, 2017: Environment International
https://www.readbyqxmd.com/read/28544220/gdm-shades-of-gray
#4
Robert M Silver
In this issue of BJOG, Kapur and colleagues call for all European women to undergo screening for gestational diabetes (GDM) as recommended by FIGO (Kapur et al., BJOG 2017 XX). They rightly note the adverse fetal, neonatal, and maternal effects of GDM as well as possible downstream implications for the mother and child. Their recommendations echo those of several leading organizations including FIGO. However, despite these recommendations, some European countries, communities, hospitals and clinicians do not screen all women for GDM...
May 24, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28538390/decreased-cord-blood-estradiol-levels-in-related-to-mothers-with-gestational-diabetes
#5
Xiuyu Qi, Bo Gong, Jing Yu, Limin Shen, Wanling Jin, Zhenmin Wu, Jieyun Wang, Jie Wang, Zhiqi Li
Recent studies have revealed a link between estradiol (E2) and glucose homeostasis. We aimed to assess the association between cord blood hormone levels and the risk of gestational diabetes mellitus (GDM).A total of 204 pregnant women with GDM and 204 pregnant women without GDM (control) were included in the study. Maternal GDM were diagnosed using a 75 g oral glucose tolerance test at 24 to 26 weeks of gestation. Cord blood samples from neonates were collected immediately post delivery. Controls, which were randomly selected from the study population, were matched (cases to controls ratio: 1:1) to cases by age, sex of fetus, and gestational week...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538089/central-hematocrit-levels-in-fetal-malnourished-term-infants
#6
Kerem Ertaş, Özgül Salihoğlu, Emrah Can, Sami Hatipoğlu, Şahin Hamilçikan
BACKROUND: Fetal malnutrition is especially important for common chronic diseases in adult life. They could potentially be prevented by achieving optimal fetal nutrition. OBJECTIVE: The aim of this study was to investigate hematocrit levels of malnourished, term, appropriate for gestational age (AGA) neonates. SUBJECTS AND METHODS: A total of 80 AGA neonates (between 10% and 90% percentiles interval according to birth week), born with spontaneous vaginal delivery between 37 and 42 weeks of gestation, detected by both last menstrual period and ultrasonography measurements, were included in the study...
May 23, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28532720/the-dietary-composition-of-women-who-delivered-preterm-and-full-term-infants
#7
Wioletta Waksmańska, Rafał Bobiński, Izabela Ulman-Włodarz, Anna Pielesz, Monika Mikulska
OBJECTIVES: Literature data show that excess and primary deficiency in particular nutrients, vitamins and minerals may lead to pre-eclampsia, gestational diabetes, hypertension and neural tube defects in the foetus. The aim of the study was to determine differences in average daily consumption of selected nutrients during pregnancy in women who did not supplement their diet and to evaluate the influence of dietary habits on the occurrence of pre-term delivery and hypertension in pregnant women...
June 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28532199/determination-of-the-fetal-myocardial-performance-index-in-women-with-gestational-impaired-glucose-tolerance-and-to-assess-whether-this-parameter-is-a-possible-prognostic-indicator-of-adverse-fetal-outcome
#8
Ismail Bhorat, Morgan Pillay, Tarylee Reddy
AIM: The aim of this study was to investigate if the myocardial performance index (MPI) is altered in fetuses in women with gestational impaired glucose tolerance (GIGT), controlled on diet and whether this parameter is also predictive of adverse outcome in this group, as in poorly controlled gestational diabetes. METHOD: In a prospective cross-sectional study thirty two women with gestational impaired glucose tolerance on diet in the 3(rd) trimester were recruited and matched with 32 women with normal pregnancies (control group)...
May 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28505681/prenatal-care-adherence-and-neonatal-intensive-care-unit-admission-or-stillbirth-among-women-with-gestational-and-preexisting-diabetes-mellitus
#9
Jeffrey Daniel Sperling, Lindsay Maggio, Phinnara Has, Julie Daley, Amrin Khander, Donald R Coustan
No abstract text is available yet for this article.
May 15, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28505205/associations-of-mid-pregnancy-hba1c-with-gestational-diabetes-and-risk-of-adverse-pregnancy-outcomes-in-high-risk-taiwanese-women
#10
Yi-Ran Ho, Panchalli Wang, Mei-Chun Lu, Shih-Ting Tseng, Chun-Pai Yang, Yuan-Horng Yan
BACKGROUND: The objective of this study was to investigate the associations among the mid-pregnancy glycated hemoglobin A1c (HbA1c) level, gestational diabetes (GDM), and risk of adverse pregnancy outcomes in women without overt diabetes and with positive 50-g, 1-h glucose challenge test (GCT) results (140 mg/dL or greater). METHODS: This prospective study enrolled 1,989 pregnant Taiwanese women. A two-step approach, including a 50-g, 1-h GCT and 100-g, 3-h oral glucose tolerance test (OGTT), was employed for the diagnosis of GDM at weeks 23-32...
2017: PloS One
https://www.readbyqxmd.com/read/28503212/associations-between-maternal-risk-factors-of-adverse-pregnancy-and-birth-outcomes-and-the-offspring-epigenetic-clock-of-gestational-age-at-birth
#11
Polina Girchenko, Jari Lahti, Darina Czamara, Anna K Knight, Meaghan J Jones, Anna Suarez, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M Villa, Rebecca M Reynolds, Michael S Kobor, Alicia K Smith, Elisabeth B Binder, Katri Räikkönen
BACKGROUND: A recent study has shown that it is possible to accurately estimate gestational age (GA) at birth from the DNA methylation (DNAm) of fetal umbilical cord blood/newborn blood spots. This DNAm GA predictor may provide additional information relevant to developmental stage. In 814 mother-neonate pairs, we evaluated the associations between DNAm GA and a number of maternal and offspring characteristics. These characteristics reflect prenatal environmental adversity and are expected to influence newborn developmental stage...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28491927/iron-supplements-for-infants-at-risk-for-iron-deficiency
#12
Brianna C MacQueen, Vickie L Baer, Danielle M Scott, Con Yee Ling, Elizabeth A O'Brien, Caitlin Boyer, Erick Henry, Robert E Fleming, Robert D Christensen
Professional societies have published recommendations for iron dosing of preterm neonates, but differences exist between guidelines. To help develop standardized guidelines, we performed a 10-year analysis of iron dosing in groups at risk for iron deficiency: IDM (infants of diabetic mothers), SGA (small for gestational age), and VLBW premature neonates (very low birth weight, <1500 g). We analyzed iron dosing after red cell transfusions and erythropoiesis-stimulating agents (ESA). Of IDM, 11.8% received iron in the hospital; 9...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28490415/maternal-and-perinatal-characteristics-of-small-for-gestational-age-newborns-ten-year-experience-of-a-single-center
#13
Nihal Şahin Uysal, Çağrı Gülümser, Filiz Bilgin Yanık
OBJECTIVE: The aim of this study was to analyze the maternal and perinatal characteristics of small for gestational age (SGA) newborns compared to appropriate for gestational age (AGA) newborns in singleton pregnancies managed at our hospital between January 2006 and December 2015. MATERIAL AND METHODS: The study (n=456) and control (n=4925) groups included pregnancies resulting in SGA and AGA newborns, respectively. Additionally, two SGA subgroups were defined according to abnormal (n=34) and normal (n=57) Doppler findings...
May 11, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28488900/isolated-polyhydramnios-in-the-third-trimester-is-a-gestational-diabetes-evaluation-of-value
#14
Maya Frank Wolf, David Peleg, Talia Stahl-Rosenzweig, Yaffa Kurzweil, Yariv Yogev
We evaluated implications of testing for gestational diabetes mellitus (GDM) in pregnancies complicated by third trimester isolated polyhydramnios with previous negative diabetes screening test. In this retrospective cohort study of 104 pregnant women with polyhydramnios between 2005 and 2013, all had normal first trimester fasting glucose and normal glucose challenge test (GCT < 140 mg/dL). Late onset GDM was diagnosed in five women (4.8%) with isolated polyhydramnios, one abnormal value in the oral glucose tolerance test (OGTT) was identified in four additional women (3...
May 10, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28475161/effect-of-probiotics-on-metabolic-outcomes-in-pregnant-women-with-gestational-diabetes-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Bonnie L Taylor, Georgia E Woodfall, Katherine E Sheedy, Meggan L O'Riley, Kelsie A Rainbow, Elsa L Bramwell, Nicole J Kellow
The metabolic effects of probiotic administration in women with gestational diabetes mellitus (GDM) is unknown. The objective of this review was to investigate the effect of probiotics on fasting plasma glucose (FPG), insulin resistance (HOMA-IR) and LDL-cholesterol levels in pregnant women diagnosed with GDM. Seven electronic databases were searched for RCTs published in English between 2001 and 2017 investigating the metabolic effects of a 6-8 week dietary probiotic intervention in pregnant women following diagnosis with GDM...
May 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28472859/lifestyle-interventions-for-the-treatment-of-women-with-gestational-diabetes
#16
REVIEW
Julie Brown, Nisreen A Alwan, Jane West, Stephen Brown, Christopher Jd McKinlay, Diane Farrar, Caroline A Crowther
BACKGROUND: Gestational diabetes (GDM) is glucose intolerance, first recognised in pregnancy and usually resolving after birth. GDM is associated with both short- and long-term adverse effects for the mother and her infant. Lifestyle interventions are the primary therapeutic strategy for many women with GDM. OBJECTIVES: To evaluate the effects of combined lifestyle interventions with or without pharmacotherapy in treating women with gestational diabetes. SEARCH METHODS: We searched the Pregnancy and Childbirth Group's Trials Register (14 May 2016), ClinicalTrials...
May 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28469094/relationship-between-oral-glucose-tolerance-test-characteristics-and-adverse-pregnancy-outcomes-among-women-with-gestational-diabetes-mellitus
#17
Hui Feng, Wei-Wei Zhu, Hui-Xia Yang, Yu-Mei Wei, Chen Wang, Ri-Na Su, Moshe Hod, Eran Hadar
BACKGROUND: Hyperglycemia is associated with adverse pregnancy outcomes. However, the relationships between them remain ambiguous. This study aimed to analyze the effect of different oral glucose tolerance test (OGTT) results on adverse perinatal outcomes. METHODS: This retrospective cohort study included data from 15 hospitals in Beijing from June 20, 2013 to November 30, 2013. Women with gestational diabetes mellitus (GDM) were categorized according to the number and distribution of abnormal OGTT values, and the characteristics of adverse pregnancy outcomes were evaluated...
May 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28464913/prevalence-of-hyperglycaemia-first-detected-during-pregnancy-and-subsequent-obstetric-outcomes-at-st-francis-hospital-nsambya
#18
Betty Nakabuye, Silver Bahendeka, Romano Byaruhanga
BACKGROUND: Women with hyperglycaemia detected during pregnancy are at greater risk for adverse pregnancy outcomes. Data on hyperglycaemia in pregnancy in sub-Saharan Africa is scanty and varied depending on the populations studied and the methodologies used to define hyperglycaemia in pregnancy. With the recent 2013 World Health Organisation (WHO) diagnostic criteria and classification, there is yet no sufficient data on the prevalence of hyperglycaemia in sub-Saharan Africa. The objective was to determine the prevalence of Hyperglycaemia first detected during pregnancy and subsequent obstetric outcomes among patients attending antenatal care (ANC) at St...
May 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28463829/prenatal-sacral-anomalies-leading-to-the-detection-of-associated-spinal-cord-malformations
#19
Baptiste Morel, Stéphanie Friszer, Jean-Marie Jouannic, Hubert Ducou Le Pointe, Eléonore Blondiaux, Catherine Garel
INTRODUCTION: Systematic analysis of the spine is recommended as part of the basic sonographic examination. The aim of our study is to assess the proportion of spinal cord anomalies diagnosed following detection of a sacral anomaly. MATERIAL AND METHODS: We analyzed retrospectively collected data in a prenatal tertiary center during a 9-year period. Patients were referred for second-line ultrasound in the context of diabetes mellitus or following detection of pelvic or lower spine anomalies...
May 3, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28462873/maternal-obesity-and-obstetric-outcomes-in-a-tertiary-referral-center
#20
Gitana Ramonienė, Laima Maleckienė, Rūta Jolanta Nadišauskienė, Eglė Bartusevičienė, Dalia Regina Railaitė, Regina Mačiulevičienė, Almantas Maleckas
BACKGROUND AND AIM: Obese women are at an increased risk of various adverse pregnancy outcomes. The aim of our study was to evaluate the impact of obesity on maternal and neonatal outcomes in a tertiary referral center and to compare obstetric outcomes by the level of maternal obesity. MATERIALS AND METHODS: A cohort study included 3247 women with singleton gestations who gave birth at the Department of Obstetrics and Gynecology, Lithuanian University of Health Sciences, in 2010...
April 19, 2017: Medicina
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