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neonatal diabetes and gestational diabetes

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https://www.readbyqxmd.com/read/29450884/is-sonographically-measured-cervical-length-at-37-weeks-gestation-associated-with-intrapartum-cesarean-section-a-prospective-cohort-study
#1
Bradley de Vries, Rajit Narayan, Kevin McGeechan, Stanley Santiagu, Ramesh Vairavan, Minke Burke, Hala Phipps, Jon Hyett
Cesarean section rates continue to increase globally. Prediction of intrapartum cesarean section could lead to preventative measures. Our aim was to assess the association between sonographically measured cervical length at 37 weeks' gestation and cesarean section among women planning a vaginal birth. The population was women with a low risk pregnancy or with gestational diabetes MATERIAL AND METHODS: This was a prospective cohort study conducted in a tertiary referral hospital in Sydney, Australia. 212 women with a low risk pregnancy or with gestational diabetes were recruited including 158 nulliparous and 54 parous women...
February 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29438637/population-attributable-fractions-of-perinatal-outcomes-for-nulliparous-women-associated-with-overweight-and-obesity-1990-2014
#2
Kate Cheney, Rachel Farber, Alexandra L Barratt, Kevin McGeechan, Bradley de Vries, Robert Ogle, Kirsten I Black
OBJECTIVE: To examine the prevalence across 25 years of overweight and obesity among nulliparous Australian women during early pregnancy; to estimate the proportions of adverse perinatal outcomes attributable to overweight and obesity in this population. DESIGN: Cohort study; retrospective analysis of electronic maternity data. Setting, participants: 42 582 nulliparous women with singleton pregnancies giving birth at the Royal Prince Alfred Hospital, an urban teaching hospital in Sydney, January 1990 - December 2014...
February 19, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29425836/the-impact-of-a-daily-smartphone-based-feedback-system-among-women-with-gestational-diabetes-on-compliance-glycemic-control-satisfaction-and-pregnancy-outcome-a-randomized-controlled-trial
#3
Hadas Miremberg, Tal Ben-Ari, Tal Betzer, Hagit Raphaeli, Rose Gasnier, Giulia Barda, Jacob Bar, Eran Weiner
BACKGROUND: Patient compliance and tight glycemic control have been demonstrated to improve pregnancy outcome in pregnancies complicated by gestational diabetes mellitus (GDM). The use of advanced technological tools, including smartphone-based platforms, to improve medical care and outcomes has been demonstrated in various fields of medicine, but only few small studies were performed with GDM patients. OBJECTIVE: We aimed to study the impact of introducing a smartphone-based daily feedback and communication platform between GDM patients and their physicians, on patient compliance, glycemic control, pregnancy outcome, and patient satisfaction...
February 6, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29425107/screening-for-gestational-diabetes-in-low-risk-women-effect-of-maternal-age
#4
Aida Kalok, Pravin Peraba, Shamsul Azhar Shah, Zaleha Abdullah Mahdy, Mohamad Abdul Jamil, Nirmala Kampan, Suraya Sulaiman, Nor Azlin Mohamed Ismail
Background Gestational diabetes mellitus (GDM) is on the rise globally and there are various screening guidelines with regard to patients' criteria. Materials and methods We conducted a prospective cross-sectional study to determine the prevalence of GDM amongst low-risk pregnant women above the age of 25 years. A modified glucose tolerance test (MGTT) was performed between 24 and 36 weeks of gestation. Women with GDM were divided into two groups for analysis: age between 25 and 34 years (group A) and above 35 years (group B)...
February 9, 2018: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29423911/planned-birth-at-or-near-term-for-improving-health-outcomes-for-pregnant-women-with-pre-existing-diabetes-and-their-infants
#5
REVIEW
Linda M Biesty, Aoife M Egan, Fidelma Dunne, Valerie Smith, Pauline Meskell, Eugene Dempsey, G Meabh Ni Bhuinneain, Declan Devane
BACKGROUND: Pregnant women with pre-existing diabetes (Type 1 or Type 2) have increased rates of adverse maternal and neonatal outcomes. Current clinical guidelines support elective birth, at or near term, because of increased perinatal mortality during the third trimester of pregnancy.This review replaces a review previously published in 2001 that included "diabetic pregnant women", which has now been split into two reviews. This current review focuses on pregnant women with pre-existing diabetes (Type 1 or Type 2) and a sister review focuses on women with gestational diabetes...
February 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29422092/a-rare-presentation-of-pheochromocytoma-in-pregnancy-a-case-report
#6
Seyedeh Noushin Ghalandarpoor-Attar, Seyedeh Mojgan Ghalandarpoor-Attar, Sedigheh Borna, Fahimeh Ghotbizadeh
BACKGROUND: Early diagnosis of pheochromocytoma and its proper management can lessen its mortality and morbidity. This case report describes a 24-year-old pregnant woman with an unusual presentation of pheochromocytoma. CASE PRESENTATION: An Iranian 24-year-old primigravid woman from Kordistan province was referred to our center with left flank pain at 37 weeks of gestation. She had a history of gestational diabetes mellitus since the 12th week of gestation which was managed by insulin administration...
February 9, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29420411/maternal-and-perinatal-outcomes-after-laparoscopic-sleeve-gastrectomy
#7
Amihai Rottenstreich, Uriel Elchalal, Geffen Kleinstern, Nahum Beglaibter, Abed Khalaileh, Ram Elazary
OBJECTIVE: To examine associations of laparoscopic sleeve gastrectomy with maternal and perinatal outcomes. METHODS: We conducted a retrospective case-control study of deliveries that occurred from 2006 to 2016 at two university hospitals. The study group comprised all women who had undergone laparoscopic sleeve gastrectomy and who delivered during the study period. If a woman had more than one pregnancy during the study period, data from only her first pregnancy were used...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29415674/observations-on-the-health-of-infants-at-a-time-of-rapid-societal-change-a-longitudinal-study-from-birth-to-fifteen-months-in-abu-dhabi
#8
Hazel Gardner, Katherine Green, Andrew S Gardner, Donna Geddes
BACKGROUND: Rapid economic and cultural transition in the United Arab Emirates has been accompanied by a rise in chronic disease. Early childhood is known to affect health outcomes in adulthood. This prospective longitudinal study examined the general health of Emirati infants born in a government maternity hospital in the Emirate of Abu Dhabi in October 2002. METHODS: One hundred twenty-five women, who had recently given birth, were interviewed as part of a larger study encompassing a wide range of cultural, social, and behavioural aspects of health...
February 7, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29411343/does-reactive-hypoglycemia-during-the-100-g-oral-glucose-tolerance-test-adversely-affect-perinatal-outcomes
#9
Ilhan Bahri Delibas, Sema Tanriverdi, Bulent Cakmak
OBJECTIVES: To determine whether pregnant women who have reactive hypoglycemia during the 100 g oral glucose toler-ance test (OGTT) are at an increased risk of poor pregnancy outcomes. MATERIAL AND METHODS: We retrospectively analyzed perinatal data from 413 women who underwent a 3 h OGTT at 24-28 weeks of gestation and gave birth in our clinics between January 2012 and December 2014. RESULTS: According to OGTT results, the majority of the subjects were normoglycemic (n = 316, 76...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29408586/a-prospective-cohort-study-of-fetal-heart-rate-monitoring-deceleration-area-is-predictive-of-fetal-acidemia
#10
Alison G Cahill, Methodius G Tuuli, Molly J Stout, Julia D López, George A Macones
BACKGROUND: Intrapartum electronic fetal monitoring (EFM) is the most commonly used tool in obstetrics in the United States, however, which EFM patterns predict acidemia remains unclear. OBJECTIVE: This study was designed to describe the frequency of patterns seen in labor using modern nomenclature, and to test the hypothesis that visually interpreted patterns are associated with acidemia and morbidities in term infants. We further identified patterns prior to delivery, alone or in combination, predictive of acidemia and neonatal morbidity...
January 31, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29402158/obstetric-outcomes-and-placental-findings-in-gestational-diabetes-patients-according-to-maternal-prepregnancy-weight-and-weight-gain
#11
Hadas Ganer Herman, Ann Dekalo, Lora Jubran, Letizia Schreiber, Jacob Bar, Michal Kovo
OBJECTIVE: We assessed clinical outcomes and placental pathology among pregnancies complicated with gestational diabetes mellitus (GDM) according to their pregestational body mass index (BMI) and weight gain during pregnancy. STUDY DESIGN: Pregnancy outcome and placental pathological reports of all GDM deliveries, during 2009-2015, were reviewed. We compared women with pregestational BMI > 30 and or gestational weight gain >20 kg (high-BMI group), and women with pregestational BMI < 30 and weight gain less than 20 kg (normal BMI group)...
February 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29399727/implications-of-lipids-in-neonatal-body-weight-and-fat-mass-in-gestational-diabetic-mothers-and-non-diabetic-controls
#12
REVIEW
Emilio Herrera, Henar Ortega-Senovilla
PURPOSE OF REVIEW: Maternal lipid metabolism greatly changes during pregnancy and we review in this article how they influence fetal adiposity and growth under non-diabetic and gestational diabetic conditions. RECENT FINDINGS: In pregnant women without diabetes (control), maternal glycemia correlates with neonatal glycemia, neonatal body weight and fat mass. In pregnant women with gestational diabetes mellitus (GDM), maternal glucose correlates with neither neonatal glycemia, neonatal birth weight nor fat mass, but maternal triacylglycerols (TAG), non-esterified fatty acids (NEFA) and glycerol do correlate with birth weight and neonatal adiposity...
February 5, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29399663/can-diabetes-be-controlled-by-lifestyle-activities
#13
P Hemachandra Reddy
Diabetes is a complex disease that affects millions of people worldwide. Diabetes is a metabolic disease, in which increased blood glucose levels ultimately lead to heart disease, stroke, kidney failure, foot ulcers, and damage to the eyes. Current prevalence rates of diabetes are extremely high in countries throughout the world. Multiple forms of diabetes have been identified, including type 1, type 2, type 3, neonatal and gestational. The purpose of this article is to discuss recent developments in diabetes research, including prevalence, morbidity and mortality rates, and lifestyle factors that are associated with diabetes onset and progression...
March 2017: Current Research in Diabetes & Obesity Journal
https://www.readbyqxmd.com/read/29390907/impact-of-late-pregnancy-haemoglobin-a1c-at-29-30-weeks-gestation-on-adverse-pregnancy-outcomes-among-women-with-pre-existing-diabetes-a-retrospective-analysis
#14
Soon Leong Yong, Beng Kwang Ng, Muhammad Abdul Jamil Mohd Yassin, Syed Zulkifli Syed Zakaria, Nor Azlin Mohamed Ismail
This study was to assess the relationship between late pregnancy haemoglobin A1C (HbA1C) at 29-30 weeks of gestation and adverse pregnancy outcomes (APOs) in 272 pregnant women with pre-existing diabetes. HbA1C ≥6.1% was associated with significantly increased risk of preterm delivery, Caesarean section, large for gestational age (LGA), neonatal respiratory distress, neonatal hypoglycaemia, and composite adverse neonatal outcome (p < .05). The risk of pre-eclampsia increased significantly at the lower HbA1C cut-off of > 5...
February 1, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29379161/the-impact-of-first-trimester-fasting-glucose-level-on-adverse-perinatal-outcome
#15
Lina Salman, Nissim Arbib, Adi Borovich, Anat Shmueli, Rony Chen, Arnon Wiznitzer, Eran Hadar
OBJECTIVE: To evaluate the impact of first trimester fasting glucose (FTFG) level on perinatal outcome. STUDY DESIGN: A retrospective cohort study of singleton deliveries. Maternal and neonatal outcome were compared between two groups-women with FTFG < 95 mg/dl and FTFG ≥ 95 mg/dl. Women with pre-gestational diabetes were excluded. RESULTS: Five thousand and thirty women met inclusion criteria. Of whom, 4644 (92.3%) had FTFG < 95 mg/dl and 386 (7...
January 29, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29374883/-analysis-of-pregnancy-outcomes-of-polycystic-ovary-syndrome-patients-after-frozen-embryo-transfer
#16
X D Lyu, J Qiao
Objective: To investigate pregnancy outcomes of the patients with polycystic ovary syndrome (PCOS) after frozen embryo transfer (FET) . Methods: Data of 2 367 PCOS patients received in vitro fertilization-embryo transfer [including fresh embryo transfer (fET) and FET] from January 2009 to December 2015 in Peking University Third Hospital were evaluated retrospectively. The basal characteristics, pregnancy complications and outcomes were analyzed, then identified the relative factors followed. Results: Totally 2 367 patients received in vitro fertilization-embryo transfer: 1 106 were treated with fET, and the rest 1 261 cases were treated with FET...
January 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29360555/pilot-study-of-eeg-in-neonates-born-to-mothers-with-gestational-diabetes-mellitus
#17
Pauline Léveillé-, Mathieu Hamel, Jean-Luc Ardilouze, Jean-Charles Pasquier, Charles Deacon, Kevin Whittingstall, Mélanie Plourde
BACKGROUND: The goal was to evaluate whether there was neurodevelopmental deficits in newborns born to mothers with gestational diabetes mellitus (GDM) compared to control newborns born to healthy mothers. METHODS: Forty-six pregnant women (21 controls and 25 GDM) were recruited. Electroencephalogram (EEG) was recorded in the newborns within 48 h after birth. The EEG signal was quantitatively analyzed using power spectral density (PSD); coherence between hemispheres was calculated in paired channels of frontal, temporal, central and occipital regions...
February 1, 2018: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29356579/insulin-treatment-cannot-promote-lipogenesis-in-rat-fetal-lung-in-gestational-diabetes-mellitus-because-of-failure-to-redress-the-imbalance-among-srebp-1-scap-and-insig-1
#18
Jinyan Li, Guanhua Qian, Xiaocui Zhong, Tinghe Yu
Gestational diabetes mellitus (GDM) has a higher incidence of neonatal respiratory distress syndrome, and lipogenesis is required for the synthesis of pulmonary surfactants. The aim of this study was to determine the effect of insulin treatment in GDM on the production of lipids in the lungs of fetal rats. GDM was induced by streptozotocin, and insulin was used to manage diabetes. Type II alveolar epithelial cells (AEC II), bronchoalveolar lavage fluid (BALF), and lung tissues of the neonatal rats were sampled for analyses...
January 22, 2018: DNA and Cell Biology
https://www.readbyqxmd.com/read/29352491/continuous-glucose-monitoring-in-pregnant-women-with-type-1-diabetes-benefits-for-mothers-using-pumps-or-pens-and-their-babies
#19
Denice S Feig, Helen R Murphy
AIMS: To review the current literature on the use of continuous glucose monitoring during pregnancy in women with Type 1 diabetes. METHODS: We searched the literature for randomized controlled trials using continuous glucose monitoring during pregnancy in women with Type 1 diabetes. RESULTS: Three randomized trials were found and discussed in this review. One UK study found a reduction in large-for-gestational-age infants; however, only masked continuous glucose monitoring was used in that study...
January 20, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29351483/prenatal-exposure-to-diesel-exhaust-pm2-5-causes-offspring-%C3%AE-cell-dysfunction-in-adulthood
#20
Minjie Chen, Shuai Liang, Xiaobo Qin, Li Zhang, Lianglin Qiu, Sufang Chen, Ziying Hu, Yanyi Xu, Wanjun Wang, Yuhao Zhang, Qi Cao, Zhekang Ying
BACKGROUND: Environmental stressors that encounter in early-life and cause abnormal fetal and/or neonatal development may increase susceptibility to non-communicable diseases such as diabetes. Maternal exposure to ambient fine particulate matter (PM2.5) is associated with various fetal abnormalities, suggesting that it may program offspring's susceptibility to diabetes. In the present study, we therefore examined whether maternal exposure to diesel exhaust PM2.5 (DEP), one of the major sources of ambient PM2...
December 26, 2017: American Journal of Physiology. Endocrinology and Metabolism
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