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https://www.readbyqxmd.com/read/28454029/aerosol-contributions-at-an-urban-background-site-in-eastern-mediterranean-potential-source-regions-of-pahs-in-pm10-mass
#1
Konstantinos Dimitriou, Pavlos Kassomenos
In this paper, two backward air mass trajectory-based models (Potential Source Contribution Function [PSCF] and Concentration Weighted Trajectory [CWT]) were combined, aiming to identify sources and factors defining the load of PM in the city of Limassol (Cyprus). The study also focused on the determination of atmospheric pathways enriching the aerosol phase of four carcinogenic Polycyclic Aromatic Hydrocarbons (PAHs): Benzo(a)pyrene (BaP), Benzo(a)anthracene (BaA), Benzo(b)fluoranthene (BbF) and Benzo(k)fluoranthene (BkF), in PM10 mass...
April 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28453839/virucidal-activity-of-world-health-organization-recommended-formulations-against-enveloped-viruses-including-zika-ebola-and-emerging-coronaviruses
#2
Anindya Siddharta, Stephanie Pfaender, Nathalie Jane Vielle, Ronald Dijkman, Martina Friesland, Britta Becker, Jaewon Yang, Michael Engelmann, Daniel Todt, Marc P Windisch, Florian H Brill, Joerg Steinmann, Jochen Steinmann, Stephan Becker, Marco P Alves, Thomas Pietschmann, Markus Eickmann, Volker Thiel, Eike Steinmann
The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations...
March 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28446998/pathology-of-esophageal-cancer-and-barrett-s-esophagus
#3
REVIEW
Shilpa Jain, Sadhna Dhingra
Esophageal cancer is a serious malignancy with high mortality. The two common distinctive pathologic subtypes of esophageal cancer are squamous cell carcinoma and adenocarcinoma. These differ with regards to etiology, ethnic distribution, pathogenesis, and location in the esophagus. The precursor lesions are also unique to each subtype. Squamous cell carcinoma is more common in East Asia, is linked to smoking and tobacco use, more commonly involves the middle esophagus, and the precursor lesion is squamous dysplasia...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28446791/tissue-distribution-of-the-mers-coronavirus-receptor-in-bats
#4
W Widagdo, Lineke Begeman, Debby Schipper, Peter R van Run, Andrew A Cunningham, Nils Kley, Chantal B Reusken, Bart L Haagmans, Judith M A van den Brand
Middle East respiratory syndrome coronavirus (MERS-CoV) has been shown to infect both humans and dromedary camels using dipeptidyl peptidase-4 (DPP4) as its receptor. The distribution of DPP4 in the respiratory tract tissues of humans and camels reflects MERS-CoV tropism. Apart from dromedary camels, insectivorous bats are suggested as another natural reservoir for MERS-like-CoVs. In order to gain insight on the tropism of these viruses in bats, we studied the DPP4 distribution in the respiratory and extra-respiratory tissues of two frugivorous bat species (Epomophorus gambianus and Rousettus aegyptiacus) and two insectivorous bat species (Pipistrellus pipistrellus and Eptesicus serotinus)...
April 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28444873/hematologic-hepatic-and-renal-function-changes-in-hospitalized-patients-with-middle-east-respiratory-syndrome-coronavirus
#5
J A Al-Tawfiq, K Hinedi, S Abbasi, M Babiker, A Sunji, M Eltigani
BACKGROUND: There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection. METHODS: This is a retrospective cohort study of 16 MERS-CoV patients, to describe the hematological, hepatic, and renal findings of patients with MERS-CoV. RESULTS: During the 21 days of observation, there was no significant change in the hepatic panel or creatinine tests...
April 26, 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28444154/infectivity-of-an-asymptomatic-patient-with-middle-east-respiratory-syndrome-coronavirus-infection
#6
Soo-Youn Moon, Jun Seong Son
During the MERS outbreak in Korea, one case of asymptomatic or mild MERS-CoV infection was noted. Eighty-two persons were exposed to the case without protection. They were isolated and RT-PCR and serology for MERS were performed. There was no transmission through an asymptomatic MERS case in this study.
April 22, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28442750/hepatitis-a-virus-infections-and-outbreaks-in-asylum-seekers-arriving-to-germany-september-2015-to-march-2016
#7
Kai Michaelis, Jürgen J Wenzel, Klaus Stark, Mirko Faber
From September 2015 to March 2016, hepatitis A notifications in Germany increased by 45% to 699 cases compared to 482 cases in the same period of the previous year. Children aged five to nine years were predominantly affected (22% of all cases in this period). We hypothesized that this increase could be explained by the marked influx of asylum seekers in this time period. We analysed national surveillance data and estimated the number of imported and autochthonous hepatitis A cases in asylum seekers. We also investigated molecular signatures of hepatitis A viruses sampled from asylum seekers to identify chains of transmission...
April 26, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28442259/microbial-community-structure-and-diversity-in-a-municipal-solid-waste-landfill
#8
Xiaolin Wang, Aixin Cao, Guozhu Zhao, Chuanbin Zhou, Rui Xu
Municipal solid waste (MSW) landfills are the most prevalent waste disposal method and constitute one of the largest sources of anthropogenic methane emissions in the world. Microbial activities in disposed waste play a crucial role in greenhouse gas emissions; however, only a few studies have examined metagenomic microbial profiles in landfills. Here, the MiSeq high-throughput sequencing method was applied for the first time to examine microbial diversity of the cover soil and stored waste located at different depths (0-150cm) in a typical MSW landfill in Yangzhou City, East China...
April 22, 2017: Waste Management
https://www.readbyqxmd.com/read/28440429/cathepsin%C3%A2-b-expression-in-colorectal-cancer-in-a-middle-east-population-potential-value-as-a-tumor-biomarker-for-late-disease-stages
#9
Maha-Hamadien Abdulla, Mansoor-Ali Valli-Mohammed, Khayal Al-Khayal, Abdulmalik Al Shkieh, Ahmad Zubaidi, Rehan Ahmad, Khalid Al-Saleh, Omar Al-Obeed, James McKerrow
Cathepsin B (CTSB), is a cysteine protease belonging to the cathepsin (Clan CA) family. The diagnostic and prognostic significance of increased CTSB in the serum of cancer patients have been evaluated for some tumor types. CTSB serum and protein levels have also been reported previously in colorectal cancer (CRC) with contradictory results. The aim of the present study was to investigate CTSB expression in CRC patients and the association of CTSB expression with various tumor stages in a Middle East population...
April 18, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28439696/back-to-the-future-part-1-the-medico-legal-autopsy-from-ancient-civilization-to-the-post-genomic-era
#10
REVIEW
Giovanni Cecchetto, Thomas Bajanowski, Rossana Cecchi, Donata Favretto, Silke Grabherr, Takaki Ishikawa, Toshikazu Kondo, Massimo Montisci, Heidi Pfeiffer, Maurizio Rippa Bonati, Dina Shokry, Marielle Vennemann, Santo Davide Ferrara
Part 1 of the review "Back to the Future" examines the historical evolution of the medico-legal autopsy and microscopy techniques, from Ancient Civilization to the Post-Genomic Era. In the section focusing on "The Past", the study of historical sources concerning the origins and development of the medico-legal autopsy, from the Bronze Age until the Middle Ages, shows how, as early as 2000 BC, the performance of autopsies for medico-legal purposes was a known and widespread practice in some ancient civilizations in Egypt, the Far East and later in Europe...
April 24, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28439207/incidence-and-perception-of-nursing-students-academic-incivility-in-oman
#11
Jansi Natarajan, Joshua Kanaabi Muliira, Jacoba van der Colff
BACKGROUND: The incidence of incivility in nursing education is increasing in most countries and it is affecting the culture of safety and the teaching-learning processes. Despite reports of increasing trends, little is known about nursing students' academic incivility in the Middle East. This study aimed at exploring the perceptions and extent of academic incivility among nursing students (NS) and nursing faculty members (NF) in a university based undergraduate nursing program in Oman...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28438633/structural-insights-into-the-interaction-of-coronavirus-papain-like-proteases-and-interferon-stimulated-gene-product-15-from-different-species
#12
Courtney M Daczkowski, John V Dzimianski, Jozlyn R Clasman, Octavia Goodwin, Andrew D Mesecar, Scott D Pegan
Severe Acute and Middle East Respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV) encode multifunctional papain-like proteases (PLPs) that have the ability to process the viral polyprotein to facilitate RNA replication as well as antagonize the host innate-immune response. The latter function involves reversing post-translational modification of cellular proteins conjugated with either ubiquitin (Ub) or Ub-like interferon stimulated gene product 15 (ISG15). Ubiquitin is known to be highly conserved among eukaryotes but surprisingly ISG15 is highly divergent among animals...
April 21, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28437138/epidemiology-of-basil-downy-mildew
#13
Yigal Cohen, Yariv Ben-Naim, Lidan Falach, Evgenia Rubin
Basil downy mildew (BDM) caused by the oomycete Peronospora belbahrii is a destructive disease of sweet basil (Ocimum basilicum) worldwide. It has originated in Uganda in the 1930's and recently spread to Europe, Middle East, Americas and the Far East. Seed transmission may be responsible to its quick global spread. The pathogen attacks leaf blades, producing chlorotic lesions with ample dark asexual spores on the lower leaf surface. Oospores may occur in the mesophyll of infected leaves. The asexual spores germinate on a wet leaf surface within 2h and penetrate into the epidermis within 4h...
April 24, 2017: Phytopathology
https://www.readbyqxmd.com/read/28435312/prevalence-of-chronic-pain-with-neuropathic-characteristics-a-randomized-telephone-survey-among-medical-center-patients-in-kuwait
#14
Nadia Zghoul, Edgar L Ross, Robert R Edwards, Adel Ahmed, Robert N Jamison
BACKGROUND: Chronic pain with neuropathic characteristics is considered to be an international health problem. However, surveys on the actual incidence of neuropathic pain have not been conducted in many Middle East countries, including Kuwait. The aim of this study was to examine the incidence of pain and medical comorbidities among a random sample of patients treated at a large medical center in Kuwait. METHODS: A list of 1,000 patients was created from the hospital medical record system, and a telephone survey was conducted on 759 patients who responded to the phone call, of which 67...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28434540/an-updated-age-for-the-xujiayao-hominin-from-the-nihewan-basin-north-china-implications-for-middle-pleistocene-human-evolution-in-east-asia
#15
Hong Ao, Chun-Ru Liu, Andrew P Roberts, Peng Zhang, Xinwen Xu
The Xujiayao site in the Nihewan Basin (North China) is one of the most important Paleolithic sites in East Asia. Twenty Homo fossils, which were previously assigned to an archaic Homo sapiens group, have been excavated along with more than 30,000 lithic artifacts and ∼5000 mammalian fossil specimens. Dating of the Xujiayao hominin has been pursued since its excavation in the 1970s, but its age has remained controversial because of limitations of the dating techniques that have been applied to available materials...
May 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28432910/total-mercury-levels-in-hair-of-children-aged-7years-before-and-after-the-great-east-japan-earthquake
#16
Nozomi Tatsuta, Kunihiko Nakai, Miyuki Iwai-Shimada, Tomoe Suzuki, Hiroshi Satoh, Katsuyuki Murata
The Great East Japan Earthquake on March 11, 2011 caused severe damage to the Sanriku coastal area, where we have been conducting a birth cohort study. The disaster occurred in the middle of 7-year-old examination. The mother-child pairs who participated in our study were compulsorily divided into two groups: the examination was finished for 157 children before the disaster, and for 335 after the disaster. We examined whether the disaster affected total mercury (THg) levels of the cohort, as well as a relationship between the THg levels at birth and at present...
April 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28431549/household-food-insecurity-is-associated-with-abdominal-but-not-general-obesity-among-iranian-children
#17
Fateme Jafari, Simin Ehsani, Azadeh Nadjarzadeh, Ahmad Esmaillzadeh, Mahmood Noori-Shadkam, Amin Salehi-Abargouei
BACKGROUND: Childhood obesity is increasing all over the world. Food insecurity is mentioned as a possible risk factor; however, previous studies have led to inconsistent results in different societies while data are lacking for the Middle East. We aimed to investigate the relationship between food insecurity and general or abdominal obesity in Iranian children in a cross-sectional study. METHODS: Anthropometric data including height, weight, and waist circumference were measured by trained nutritionists...
April 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28430830/assessment-of-global-kidney-health-care-status
#18
Aminu K Bello, Adeera Levin, Marcello Tonelli, Ikechi G Okpechi, John Feehally, David Harris, Kailash Jindal, Babatunde L Salako, Ahmed Rateb, Mohamed A Osman, Bilal Qarni, Syed Saad, Meaghan Lunney, Natasha Wiebe, Feng Ye, David W Johnson
Importance: Kidney disease is a substantial worldwide clinical and public health problem, but information about available care is limited. Objective: To collect information on the current state of readiness, capacity, and competence for the delivery of kidney care across countries and regions of the world. Design, Setting, and Participants: Questionnaire survey administered from May to September 2016 by the International Society of Nephrology (ISN) to 130 ISN-affiliated countries with sampling of key stakeholders (national nephrology society leadership, policy makers, and patient organization representatives) identified by the country and regional nephrology leadership through the ISN...
April 21, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28426782/peste-des-petits-ruminants-ppr-a-neglected-tropical-disease-in-maghreb-region-of-north-africa-and-its-threat-to-europe
#19
Ratiba Baazizi, Mana Mahapatra, Brian Donald Clarke, Khatima Ait-Oudhia, Djamel Khelef, Satya Parida
BACKGROUND: Peste des petits ruminants (PPR) is a contagious disease listed by the World Organisation for Animal health (OIE) as being a specific hazard. It affects sheep, goats, and wild ungulates, and is prevalent throughout the developing world particularly Asia, the Middle East, and Africa. PPR has been targeted for eradication by 2030 by the Food and Agriculture Organization of the United Nations (FAO) and the OIE, after the successful eradication of the related disease, rinderpest in cattle...
2017: PloS One
https://www.readbyqxmd.com/read/28426729/cultural-differences-in-room-size-perception
#20
Aurelie Saulton, Heinrich H Bülthoff, Stephan de la Rosa, Trevor J Dodds
Cultural differences in spatial perception have been little investigated, which gives rise to the impression that spatial cognitive processes might be universal. Contrary to this idea, we demonstrate cultural differences in spatial volume perception of computer generated rooms between Germans and South Koreans. We used a psychophysical task in which participants had to judge whether a rectangular room was larger or smaller than a square room of reference. We systematically varied the room rectangularity (depth to width aspect ratio) and the viewpoint (middle of the short wall vs...
2017: PloS One
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