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https://www.readbyqxmd.com/read/28953783/the-wounded-healer-film-a-london-college-of-communication-event-to-challenge-mental-health-stigma-through-the-power-of-motion-picture
#1
Ahmed Hankir, Rashid Zaman, Benjamin Geers, Gus Rosie, Grainne Breslin, Lilly Barr, Frederick R Carrick, Sal Anderson
BACKGROUND: There is a preponderance of mental health problems in students on a global scale which can have a considerable effect on their academic performance and a profound impact on their quality of life. Many universities offer free counselling services however despite this a recent study in the US revealed that up to 84% of students who screened positive for depression or anxiety did not receive any treatment. There are many obstacles that students with mental health problems encounter that prevents them from receiving care, foremost among these is stigma...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28899995/hiv-seroconversion-among-baltimore-city-residents-tested-at-a-mobile-van-programme
#2
Sarah Puryear, Phyllis Burnett, Kathleen R Page, Ravikiran Muvva, Patrick Chaulk, Khalil G Ghanem, Anne Monroe
BACKGROUND: Many individuals with HIV in the USA are unaware of their diagnosis, and therefore cannot be engaged in treatment services, have worse clinical outcomes and are more likely to transmit HIV to others. Mobile van testing may increase HIV testing and diagnosis. Our objective was to characterise risk factors for HIV seroconversion among individuals using mobile van testing. METHODS: A case cohort study (n=543) was conducted within an HIV surveillance dataset of mobile van testing users with at least two HIV tests between September 2004 and August 2009 in Baltimore, Maryland...
September 12, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28866016/disintegration-of-collagen-fibrils-by-glucono-%C3%AE-lactone-an-implied-lead-for-disintegration-of-fibrosis
#3
Jayaraman Jayamani, R Ravikanth Reddy, Balaraman Madhan, Ganesh Shanmugam
Excess accumulation of collagen (fibrosis) undergoes self-aggregation, which leads to fibrillar collagen, on the extracellular matrix is the hallmark of a number of diseases such as keloids, hypertrophic scars, and systemic scleroderma. Direct inhibition or disintegration of collagen fibrils by small molecules offer a therapeutic approach to prevent or treat the diseases related to fibrosis. Herein, the anti-fibrotic property of Glucono-δ-lactone (GdL), known as acidifier, on the fibrillation and its disintegration of collagen was investigated...
August 30, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28837587/the-current-status-of-syphilis-prevention-and-control-in-jiangsu-province-china-a-cross-sectional-study
#4
Yuan-Fang Chen, Jian-Ping Ding, Hong-Jing Yan, Jing Lu, Ping Ding, Guo-Hong Chen, Jian-Jun Li, Xi-Ping Huan, Hai-Tao Yang, Wei-Ming Tang, Geng-Feng Fu
OBJECTIVE: To analyze the midterm evaluation data from the National Syphilis Prevention and Control Plan (2010-2020) and evaluate the current status of syphilis prevention and control in Jiangsu province, China. METHODS: We collected data via (1) field surveys conducted in 2015 and (2) data recorded in existing syphilis surveillance systems. We conducted descriptive statistical analysis to evaluate the current landscape of syphilis control initiatives and their potential effect in syphilis control...
2017: PloS One
https://www.readbyqxmd.com/read/28817690/resveratrol-and-caloric-restriction-prevent-hepatic-steatosis-by-regulating-sirt1-autophagy-pathway-and-alleviating-endoplasmic-reticulum-stress-in-high-fat-diet-fed-rats
#5
Shibin Ding, Jinjin Jiang, Guofu Zhang, Yongjun Bu, Guanghui Zhang, Xiangmei Zhao
BACKGROUND: Studies have demonstrated that resveratrol (a natural polyphenol) and caloric restriction activate Sirtuin-1 (SIRT1) and induce autophagy. Furthermore, autophagy is induced by the SIRT1-FoxO signaling pathway and was recently shown to be a critical protective mechanism against non-alcoholic fatty liver disease (NAFLD) development. We aimed to compare the effects of resveratrol and caloric restriction on hepatic lipid metabolism and elucidate the mechanism by which resveratrol supplementation and caloric restriction alleviate hepatosteatosis by examining the molecular interplay between SIRT1 and autophagy...
2017: PloS One
https://www.readbyqxmd.com/read/28806949/case-report-of-ocular-kaposi-s-sarcoma
#6
Jing Yang, Xiao-Fang Yin, Yong-Ping Li, Shi-You Zhou
BACKGROUND: Kaposi's sarcoma (KS) is generally considered a neoplastic disorder of vascular origin and occurs in patients with acquired immunodeficiency syndrome (AIDS) or who have received immunosuppressive treatments after an organ transplant (Soulier et al., Blood 86(4):1276-80, 1995; Viejo-Borbolla and Schulz, AIDS Rev 5(4):222-9, 2003; Schulz, J Antimicrob Chemother 45(Suppl T3):15-27, 2000; Aversa et al. Crit Rev Oncol Hematol 53(3):253-65, 2005; Mbulaiteye and Engels, Int J Cancer 119(11):2685-91, 2006; Tessari et al...
August 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28777810/green-tea-polyphenol-treatment-attenuates-atherosclerosis-in-high-fat-diet-fed-apolipoprotein-e-knockout-mice-via-alleviating-dyslipidemia-and-up-regulating-autophagy
#7
Shibin Ding, Jinjin Jiang, Pengxin Yu, Guofu Zhang, Guanghui Zhang, Xiaoting Liu
BACKGROUND: Green tea polyphenol (GTP) is a polyphenol source from green tea that has drawn wide attention owing to epidemiological evidence of its beneficial effects in the prevention of cardiovascular disease; the underlying molecular mechanisms of these effects are not well understood. This study aimed to investigate the effects of GTP treatment on autophagy regulation in the vessel wall and lipid metabolism of HFD-fed male ApoE-knockout mice. METHODS: Adult male ApoE-knockout mice (n = 30) fed with a high-fat diet (HFD) were treated with either vehicle or GTP (3...
2017: PloS One
https://www.readbyqxmd.com/read/28612588/analysis-of-knowledge-level-in-brazilian-students-about-human-papillomavirus-infection-and-development-of-penile-cancer
#8
George Kemil Abdalla, Emanuella Francisco Fajardo, Bruno Belmonte Martinelli Gomes, Thiago Mantello Bianco, Ana Karina Marques Salge, Eduardo Elias Vieira de Carvalho, Marlize Moura Dos Reis, Dayana Pousa Siqueira Abrahão, Douglas Reis Abdalla
Introduction: Human papillomavirus (HPV), belonging to the Papovavirida family, is the most prevalent sexually transmitted disease (STD) agent worldwide. In Brazil, it is estimated that there are 3-6 million people infected with HPV. Aim: The aim of this study was to evaluate the knowledge of young male students about penis cancer related to HPV infection. Methods: This exploratory and quantitative study was conducted to analyze answers of 242 male students attending a private college located in Uberaba city, Minas Gerais state, Brazil, during 2015...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28608786/new-human-immunodeficiency-virus-diagnosis-independently-associated-with-rectal-gonorrhea-and-chlamydia-in-men-who-have-sex-with-men
#9
Lindley A Barbee, Christine M Khosropour, Julia C Dombrowksi, Matthew R Golden
BACKGROUND: Rectal sexually transmitted infections (STI) have been associated with human immunodeficiency virus (HIV) diagnosis, but inferring a causal association requires disentangling them from receptive anal intercourse (RAI). METHODS: We conducted a stratified case-control study by frequency matching 4 controls to each case within year using clinical data from men who have sex with men (MSM) attending the Seattle STD Clinic 2001 to 2014. Cases were MSM with a new HIV diagnosis and negative HIV test at 12 months or less...
July 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28499291/a-survey-of-25-north-carolina-health-departments-districts-on-knowledge-attitudes-and-current-practices-to-seeking-reimbursement-from-third-party-payers-for-sexually-transmitted-disease-services
#10
Cheryl L Kovar, Susan Carter
BACKGROUND: North Carolina Administrative Code 10A Chapter 41A.0204 (a) states "local health departments shall provide diagnosis, testing, treatment, follow-up, and preventive services for syphilis, gonorrhea, chlamydia, … These services shall be provided upon request and at no charge to the patient." Although health departments/districts may bill governmental or nongovernmental insurance providers for sexually transmitted disease (STD) services, current billing practices are unknown...
June 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28442801/treatment-outcomes-and-loss-to-follow-up-rate-of-male-patients-with-gonococcal-and-nongonococcal-urethritis-who-attended-the-sexually-transmitted-disease-clinic-an-8-year-retrospective-study
#11
Charussri Leeyaphan, Sukhum Jiamton, Pattriya Chanyachailert, Theetat Surawan, Viboon Omcharoen
BACKGROUND: Poor follow-up compliance of patients with infectious urethritis is a recognized and serious public health problem in Thailand. AIM: The aim of this study was to determine treatment outcomes and loss to follow-up rate of male patients with gonococcal urethritis (GU) and non-GU (NGU) at a sexually transmitted disease (STD) clinic at Thailand's tertiary hospital. METHODS: This retrospective chart review of male patients who sought treatment at STDs Clinic, Siriraj Hospital, and who were diagnosed with GU and/or NGU was conducted during January 2007 to December 2014 study period...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28327799/prevalence-and-factors-associated-with-syphilis-in-a-reference-center
#12
Natália Carolina Rodrigues Colombo Gomes, Denise Andrade Pereira Meier, Flávia Meneguetti Pieri, Elaine Alves, Silvia Paulino Ribeiro Albanese, Edvilson Cristiano Lentine, Ricardo Alexandre Arcêncio, Elma Mathias Dessunti
INTRODUCTION: The implementation of the rapid test (RT) for syphilis increases access of vulnerable populations to early diagnosis and treatment, impacting the outcomes of infection. We aimed to assess the prevalence of and factors associated with syphilis in a Center for Testing and Counseling (CTC). METHODS: We conducted a cross-sectional study at a Reference Center for sexually transmitted disease (STD) and acquired immune deficiency syndrome in Londrina, Northern Paraná State, Southern Brazil...
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28290950/survey-of-sexually-transmitted-disease-laboratory-methods-in-u-s-army-laboratories-2012
#13
Nicole K Leamer, Nikki N Jordan, Laura A Pacha, Nabil H Latif, Eric C Garges, Joel C Gaydos
INTRODUCTION: Sexually transmitted diseases (STD) affect primarily young people (17-24 years). The U.S. Military, with many young people, strives to maintain effective STD treatment and prevention programs using current methods. Laboratory testing technology and capacity are important for appropriate clinical management and to provide data to direct prevention programs. STD laboratory capabilities are assessed in civilian and military laboratories using surveys. An Army laboratory survey was conducted in 2007...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28208724/assessing-the-knowledge-level-attitudes-risky-behaviors-and-preventive-practices-on-sexually-transmitted-diseases-among-university-students-as-future-healthcare-providers-in-the-central-zone-of-malaysia-a-cross-sectional-study
#14
Adigun Temiloluwa Folasayo, Afolayan John Oluwasegun, Suhailah Samsudin, Siti Nor Sakinah Saudi, Malina Osman, Rukman Awang Hamat
This study was done to assess the knowledge, attitudes, risky behaviors and preventive practices related to sexually-transmitted diseases (STDs) among health and non-health sciences university students as future healthcare providers in Malaysia. A total of 700 health and non-health sciences university students (255 male; 445 female) aged between 17 and 30 years were surveyed by using a self-administered questionnaire. The majority (86.6%) had heard of STDs, and 50.4% knew STDs could present without symptoms...
February 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28199417/physical-activity-prevents-alterations-in-mitochondrial-ultrastructure-and-glucometabolic-parameters-in-a-high-sugar-diet-model
#15
Karina Barbosa de Queiroz, Kinulpe Honorato-Sampaio, Joamyr Victor Rossoni Júnior, Diego Andrade Leal, Angélica Barbosa G Pinto, Lenice Kappes-Becker, Elisio Alberto Evangelista, Renata Guerra-Sá
Endurance exercise is a remarkable intervention for the treatment of many diseases. Mitochondrial changes on skeletal muscle are likely important for many of the benefits provided by exercise. In this study, we aimed to evaluate the effects that a regular physical activity (swimming without workload) has on mitochondrial morphological alterations and glucometabolic parameters induced by a high-sugar diet (HSD). Weaned male Wistar rats fed with a standard diet or a HSD (68% carbohydrate) were subjected to 60 minutes of regular physical activity by swimming (without workload) for four- (20 sessions) or eight-week (40 sessions) periods...
2017: PloS One
https://www.readbyqxmd.com/read/28178118/microscopy-of-stained-urethral-smear-in-male-urethritis-which-cutoff-should-be-used
#16
Harald Moi, Usha Hartgill, Kristin Helene Skullerud, Elina J Reponen, Line Syvertsen, Amir Moghaddam
BACKGROUND: The microscopical diagnosis of male urethritis was recently questioned by Rietmeijer and Mettenbrink, lowering the diagnostic criteria of the diagnosis to ≥2 polymorphonuclear leucocytes (PMNL) per high power field (HPF), and adopted by Centers for Disease Control and Prevention in their 2015 STD Treatment Guidelines. The European Non-Gonococcal Urethritis Guideline advocates a limit of ≥5 PMNL/HPF. OBJECTIVE: To determine if syndromic treatment of urethritis should be considered with a cutoff value of ≥2 PMNL/HPF in urethral smear...
March 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27968882/effects-of-patient-load-and-travel-distance-on-hiv-transmission-in-a-cohort-of-serodiscordant-couples-in-rural-china-a-longitudinal-analysis
#17
M Kumi Smith, William C Miller, Huixin Liu, Chuanyi Ning, Wensheng He, Myron S Cohen, Ning Wang
BACKGROUND: Sustained viral suppression through antiretroviral therapy (ART) reduces the risk of sexual HIV transmission. However, it can require routine access to reliable and effective medical care, which can be difficult to obtain in resource-constrained areas. We investigated the effects of patient load and travel distance to an HIV care clinic on transmission risk in HIV serodiscordant couples in the Henan Province, China. METHODS: The study cohort arises from a population of HIV-infected individuals in central rural China where regional blood selling scandals in the 1990s led to mass HIV transmission of up to 30 000 people though unsanitary blood collection practices...
October 2016: Lancet
https://www.readbyqxmd.com/read/27925128/-incidence-and-mortality-of-children-and-teenagers-with-aids-challenges-in-the-southern-region-of-brazil
#18
Márcio Cristiano de Melo, Rosemeire de Olanda Ferraz, Juliana Luporini do Nascimento, Maria Rita Donalisio
The objective of this study is to describe the time trend of coefficients of incidence and mortality associated with AIDS in children and adolescents. An ecological time trend study was conducted among individuals under 14 living in the regional context of high incidence of AIDS - Porto Alegre and the State of Rio Grande do Sul - from 1996 to 2012. For this purpose, a segmented regression model was adjusted for age categories and place of residence. AIDS morbidity and mortality indicators in Porto Alegre are still higher than those registered in the State, the southern region and other areas of the country...
December 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27832703/hiv-and-sti-knowledge-testing-and-risk-among-adult-crack-users-in-mexico-city-baseline-findings-from-a-feasibility-study
#19
Alice Cepeda, Jessica Frankeberger, Jennifer L Bailey, Kathryn M Nowotny, Guillermina Natera-Rey, Avelardo Valdez
Recent research has documented crack cocaine's increasing spread in Mexico, which is likely to contribute to the rapid transmission of HIV and other sexually transmitted infections (STIs). In Mexico, crack use is increasing most rapidly in vulnerable, hard-to-reach populations, where little is known about risk behaviors. This report aims to present baseline data regarding HIV and STI knowledge and testing prevalence from an innovative projection mapping HIV intervention, in which 3-D illusions, animation, and visual text graphics and sound are projected onto buildings with health messages that were designed to disrupt everyday life and connect with the target population...
March 2017: AIDS Care
https://www.readbyqxmd.com/read/27677620/proanthocyanidins-potentiate-hypothalamic-leptin-stat3-signalling-and-pomc-gene-expression-in-rats-with-diet-induced-obesity
#20
M Ibars, A Ardid-Ruiz, M Suárez, B Muguerza, C Bladé, G Aragonès
OBJECTIVE: Dietary obesity is usually linked with hypothalamic leptin resistance, in which the primary impact is an interference in the homeostatic control of body weight and appetite. Notably, proanthocyanidins (PACs), which are the most abundant phenolic compounds present in human diet, modulate adiposity and food intake. The aim of this study was to assess whether PACs could re-establish appropriate leptin signalling in both the hypothalamus and peripheral tissues. DESIGN: Male Wistar rats were fed either a standard chow diet (STD group, n=7) or a cafeteria diet (CD) for 13 weeks...
January 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
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