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https://www.readbyqxmd.com/read/29666138/increase-in-assisted-suicide-in-switzerland-did-the-socioeconomic-predictors-change-results-from-the-swiss-national-cohort
#1
Nicole Steck, Christoph Junker, Marcel Zwahlen
OBJECTIVE: To determine whether the strong increase in assisted suicides in Switzerland since 2008 is linked to a shift in the socioeconomic factors associated with assisted suicide and its related diagnoses. METHODS: In a population-based longitudinal study, we investigated assisted suicides in Switzerland over the period 2003-2014. Two groups of younger (25-64 years) and older (65-94 years) persons were analysed separately and compared. We calculated crude rates and used Cox proportional hazard and logistic regression models to examine associations of assisted dying with gender, marital status, education, religion, neighbourhood socioeconomic status and other variables, and investigated trends over time...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29665047/neural-reward-responsiveness-in-children-who-engage-in-nonsuicidal-self-injury-an-erp-study
#2
Aliona Tsypes, Max Owens, Greg Hajcak, Brandon E Gibb
BACKGROUND: A better understanding of the correlates of nonsuicidal self-injury (NSSI) in children is important for the identification and prevention of future suicide risk. However, although abnormalities in reward responsiveness might constitute one potential transdiagnostic mechanism of risk for NSSI, no studies have examined initial response to reward in children with a history of NSSI. The goal of the present study was to address this important gap in the literature. To objectively assess initial response to reward, we utilized the feedback negativity (FN) event-related potential, a well-established psychophysiological marker of reward responsiveness...
April 17, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29661941/mental-health-of-transgender-and-gender-nonconforming-youth-compared-with-their-peers
#3
Tracy A Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W Dana Flanders, Darios Getahun, Shawn V Giammattei, Enid M Hunkeler, Timothy L Lash, Andrea Millman, Virginia P Quinn, Brandi Robinson, Douglas Roblin, David E Sandberg, Michael J Silverberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California and Georgia. Ten male and 10 female referent cisgender enrollees were matched to each TGNC individual on year of birth, race and/or ethnicity, study site, and membership year of the index date (first evidence of gender nonconforming status)...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29655375/association-between-traumatic-stress-load-psychopathology-and-cognition-in-the-philadelphia-neurodevelopmental-cohort
#4
Ran Barzilay, Monica E Calkins, Tyler M Moore, Daniel H Wolf, Theodore D Satterthwaite, J Cobb Scott, Jason D Jones, Tami D Benton, Ruben C Gur, Raquel E Gur
BACKGROUND: Traumatic stressors during childhood and adolescence are associated with psychopathology, mostly studied in the context of post-traumatic stress disorder (PTSD) and depression. We investigated broader associations of traumatic stress exposure with psychopathology and cognition in a youth community sample. METHODS: The Philadelphia Neurodevelopmental Cohort (N = 9498) is an investigation of clinical and neurobehavioral phenotypes in a diverse (56% Caucasian, 33% African American, 11% other) US youth community population (aged 8-21)...
April 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29652872/medical-management-of-transgender-children-and-adolescents
#5
María Fernanda Castilla-Peón
Transgender or gender nonconforming (GN) persons identify themselves with a gender which is different from that correspondent to their birth sex. The demand for health services by families with transgender children or adolescents tends to increase. The prevalence of GN in children is unknown; however, it has been estimated to be > 1% in adolescents. Transgender persons are at increased risk of depression, suicide, illicit drug abuse, human immunodeficiency virus infection, and non-accidental injury. The most accepted model for the care of transgender persons assumes that these adverse outcomes are the consequence of social margination rather than the GI condition itself...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29651656/using-lithium-in-children-and-adolescents-with-bipolar-disorder-efficacy-tolerability-and-practical-considerations
#6
REVIEW
B Grant, J A Salpekar
Lithium has been an intriguing treatment option in psychiatry for over a century. While seemingly just a simple elemental compound, it has powerful treatment effects for both depression and bipolar disorder. The evidence base for treatment of pediatric bipolar disorder is relatively small, but, in recent years, additional clinical trial data have enabled lithium to re-emerge as a valuable and, in many cases, preferred treatment. Pharmacologically, lithium is complex, with varied effects at both intracellular and extracellular levels...
April 12, 2018: Paediatric Drugs
https://www.readbyqxmd.com/read/29649074/parental-bereavement-in-young-children-living-in-south-africa-and-malawi-understanding-mental-health
#7
A Macedo, L Sherr, M Tomlinson, S Skeen, K J Roberts
BACKGROUND: Parental loss is a major stressful event found to increase risk of mental health problems in childhood. Yet, some children show resilient adaptation in the face of adversity across time. SETTING: This study explores predictors of mental health resilience among parentally bereaved children in South Africa and Malawi, and their cumulative effect. The study also explores whether predictors of resilience differed between orphaned and non-orphaned children...
April 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29644925/suicide-in-black-children
#8
Carla Couto, Sandra Barreto, Modesto Leite Rolim Neto
No abstract text is available yet for this article.
April 1, 2018: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/29620636/clinical-characteristic-and-risk-factors-of-recurrent-sexual-abuse-and-delayed-reported-sexual-abuse-in-childhood
#9
Mei-Hua Hu, Go-Shine Huang, Jing-Long Huang, Chang-Teng Wu, An-Shine Chao, Fu-Sung Lo, Han-Ping Wu
Child sexual abuse (CSA) is a global problem that affects children of all ages, and the evaluation of these victims by psychologic and gynecologic experts in pediatric emergency departments is an important issue. Few data are available on the characteristics of children admitted to pediatric emergency department with recurrent CSA and delayed reported CSA. The aim of the present study was to describe the clinical features of, and risk factors for, recurrent CSA and delayed reported CSA. The study retrospectively analyzed victims of CSA who were admitted to a pediatric emergency department...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29604504/consequences-of-parental-burnout-its-specific-effect-on-child-neglect-and-violence
#10
Moïra Mikolajczak, Maria Elena Brianda, Hervé Avalosse, Isabelle Roskam
Parental burnout is a specific syndrome resulting from enduring exposure to chronic parenting stress. It encompasses three dimensions: an overwhelming exhaustion related to one's parental role, an emotional distancing from one's children and a sense of ineffectiveness in one's parental role. This study aims to facilitate further identification of the consequences of parental burnout for the parents themselves, their spouses and their child(ren). In a sample of 1551 parents, we examined the relationship between parental burnout and seven possible consequences: escapism and suicidal thoughts, addictions, sleep disorders, marital conflicts, a partner estrangement mindset, and neglect and violence towards one's child(ren)...
March 28, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29597289/the-epidemiology-of-unintentional-and-violence-related-injury-morbidity-and-mortality-among-children-and-adolescents-in-the-united-states
#11
Michael F Ballesteros, Dionne D Williams, Karin A Mack, Thomas R Simon, David A Sleet
Injuries and violence among young people have a substantial emotional, physical, and economic toll on society. Understanding the epidemiology of this public health problem can guide prevention efforts, help identify and reduce risk factors, and promote protective factors. We examined fatal and nonfatal unintentional injuries, injuries intentionally inflicted by other (i.e., assaults and homicides) among children ages 0-19, and intentionally self-inflicted injuries (i.e., self-harm and suicides) among children ages 10-19...
March 28, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29593617/the-role-of-difficulty-in-identifying-and-describing-feelings-in-non-suicidal-self-injury-behavior-nssi-associations-with-perceived-attachment-quality-stressful-life-events-and-suicidal-ideation
#12
Rita Cerutti, Antonio Zuffianò, Valentina Spensieri
Objective: Core alexithymic features, such as the difficulty in identifying and describing feelings, are associated with poor attachment styles and emotional trauma, which influence the capacity to regulate affect. Additionally, emotional regulation has been found to be the most commonly identified function associated with non-suicidal self-injury behavior (NSSI) in adolescents as they attempt to modulate strong emotions. However, few studies have examined the link between difficulty in identifying and describing feelings (core components of alexithymia), NSSI behaviors, quality of attachment, life stressors and suicidal ideation in healthy early adolescents...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29593583/attachment-to-parents-as-a-moderator-in-the-association-between-sibling-bullying-and-depression-or-suicidal-ideation-among-children-and-adolescents
#13
Jasmin Bar-Zomer, Anat Brunstein Klomek
Bullying is one of the most widespread phenomenon in childhood and adolescence. Interestingly, most research on bullying focuses on bullying at school and not on bullying among siblings at home. Sibling bullying is the most frequent form of repeated aggression that children experience in their lifetime. Furthermore, previous studies indicate that sibling bullying is associated with depression and self-harm behavior. However, the association between sibling bullying and suicidal ideation was never previously examined...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29590363/the-intergenerational-consequences-of-war-anxiety-depression-suicidality-and-mental-health-among-the-children-of-war-veterans
#14
Walter Forrest, Ben Edwards, Galina Daraganova
Background: The long-term effects of military deployment on the mental health of war veterans have been investigated extensively, but few studies have examined the long-term impact of parental deployment on children's mental health. Methods: Using a retrospective, multigenerational survey and propensity score analysis to adjust for selection effects and endogeneity bias, we investigated the impact of parental deployment on the mental health of the adult children of Australian veterans of the Vietnam War...
March 24, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29590281/association-of-childhood-irritability-and-depressive-anxious-mood-profiles-with-adolescent-suicidal-ideation-and-attempts
#15
Massimiliano Orri, Cedric Galera, Gustavo Turecki, Alberto Forte, Johanne Renaud, Michel Boivin, Richard E Tremblay, Sylvana M Côté, Marie-Claude Geoffroy
Importance: Suicidal ideation and suicide attempt (suicidality) are common in adolescence and a public health concern. Childhood depression is a key risk factor for later suicidality and often co-occurs with irritability. No study to date has examined the joint association of depressive mood and irritability during childhood with later suicidality. Objective: To investigate the association of childhood irritability and depressive/anxious mood profiles with adolescent suicidality...
March 28, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29587223/hallmarks-of-alzheimer-disease-are-evolving-relentlessly-in-metropolitan-mexico-city-infants-children-and-young-adults-apoe4-carriers-have-higher-suicide-risk-and-higher-odds-of-reaching-nft-stage-v-at-%C3%A2-40-years-of-age
#16
Lilian Calderón-Garcidueñas, Angélica Gónzalez-Maciel, Rafael Reynoso-Robles, Ricardo Delgado-Chávez, Partha S Mukherjee, Randy J Kulesza, Ricardo Torres-Jardón, José Ávila-Ramírez, Rodolfo Villarreal-Ríos
Exposures to fine particulate matter (PM2.5 ) and ozone (O3 ) above USEPA standards are associated with Alzheimer's disease (AD) risk. Metropolitan Mexico City (MMC) residents have life time exposures to PM2.5 and O3 above USEPA standards. We investigated AD intra and extracellular protein aggregates and ultrastructural neurovascular pathology in 203 MMC residents age 25.36 ± 9.23 y. Immunohistochemical methods were used to identify AT8 hyperphosphorilated tau (Htau) and 4G8 (amyloid β 17-24). Primary outcomes: staging of Htau and amyloid, per decade and cumulative PM2...
March 24, 2018: Environmental Research
https://www.readbyqxmd.com/read/29582079/2017-update-on-pediatric-medical-overuse-a-review
#17
Eric R Coon, Paul C Young, Ricardo A Quinonez, Daniel J Morgan, Sanket S Dhruva, Alan R Schroeder
Importance: Medical overuse has historically focused on adult health care, but interest in how children are affected by medical overuse is increasing. This review examines important research articles published in 2016 that address pediatric overuse. Observations: A structured search of PubMed and a manual review of the tables of contents of 10 journals identified 169 articles related to pediatric overuse published in 2016, from which 8 were selected based on the quality of methods and potential harm to patients in terms of prevalence and magnitude...
March 26, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29558316/the-psychometric-properties-in-the-chinese-version-of-the-reasons-for-living-inventory-and-the-relationship-with-suicidal-behaviors-among-psychiatric-patients-in-taiwan
#18
Yu-Chuan Chiu, Shen-Ing Liu, Chen-Ju Lin, Yu-Shin Huang, Chun-Kai Fang, Fang-Ju Sun, Kai-Liang Kao, Yo-Ping Huang, Shu-I Wu
This study examines the reliability, factor structure, convergent, and construct validities of the Mandarin Chinese version of the Reasons For Living Inventory (RFL) among Taiwanese psychiatric patients. Demographical characteristics of patients who hold these adaptive cognitions and differences on the level of endorsement between suicidal and non-suicidal individuals were also investigated. All adult patients that had visited the psychiatric ambulatory clinic or had been admitted to the psychiatric ward in a general hospital in Taiwan over a 3-month period were consecutively invited to complete an inventory that included background information, the Mandarin Chinese versions of the RFL, the Suicidal Behaviors Questionnaire- Revised (SBQ-R), and the Beck Hopeless Scale (BHS)...
March 20, 2018: Behavioral Medicine
https://www.readbyqxmd.com/read/29540584/randomized-dose-ranging-safety-trial-of-cannabidiol-in-dravet-syndrome
#19
Orrin Devinsky, Anup D Patel, Elizabeth A Thiele, Matthew H Wong, Richard Appleton, Cynthia L Harden, Sam Greenwood, Gilmour Morrison, Kenneth Sommerville
OBJECTIVE: To evaluate the safety and preliminary pharmacokinetics of a pharmaceutical formulation of purified cannabidiol (CBD) in children with Dravet syndrome. METHODS: Patients aged 4-10 years were randomized 4:1 to CBD (5, 10, or 20 mg/kg/d) or placebo taken twice daily. The double-blind trial comprised 4-week baseline, 3-week treatment (including titration), 10-day taper, and 4-week follow-up periods. Completers could continue in an open-label extension. Multiple pharmacokinetic blood samples were taken on the first day of dosing and at end of treatment for measurement of CBD, its metabolites 6-OH-CBD, 7-OH-CBD, and 7-COOH-CBD, and antiepileptic drugs (AEDs; clobazam and metabolite N -desmethylclobazam [N-CLB], valproate, levetiracetam, topiramate, and stiripentol)...
March 14, 2018: Neurology
https://www.readbyqxmd.com/read/29532759/amlodipine-150-mg-poisoning-a-case-study
#20
Prasan Kumar Panda, Annu Raj, Shiv Shankar Singh
Treatments of patient with amlodipine (a calcium channel blocker, CCB) overdose/poisoning remain challenging and death is certain if not intervened timely. Furthermore, for a society, the availability and common use of this drug make more vulnerable, especially by children, towards an accidental/suicidal poisoning. Here we describe an adolescent school girl who took 150 mg of amlodipine and was admitted in our hospital approximately 4 hours after ingestion with suicidal intention. She developed circulatory failure and tachypnea...
March 13, 2018: Current Drug Safety
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