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https://www.readbyqxmd.com/read/29691993/epidemiology-and-molecular-characterization-of-chicken-anaemia-virus-from-commercial-and-native-chickens-in-taiwan
#1
S-C Ou, H-L Lin, P-C Liu, H-J Huang, M-S Lee, Y-Y Lien, Y-L Tsai
Chicken infectious anaemia (CIA) is a disease with a highly economic impact in the poultry industry. The infected chickens are characterized by aplastic anaemia and extreme immunosuppression, followed by the increased susceptibility to secondary infectious pathogens and suboptimal immune responses for vaccination. Commercially available CIA vaccines are routinely used in the breeders in Taiwan to protect their progeny with maternal-derived antibodies. However, CIA cases still occur in the field and little is known about the genetic characteristics of Taiwanese chicken anaemia viruses (CAVs)...
April 25, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29691953/circulating-mots-c-levels-are-decreased-in-obese-male-children-and-adolescents-and-associated-with-insulin-resistance
#2
Caiqi Du, Cai Zhang, Wei Wu, Yan Liang, Anru Wang, Shimin Wu, Yue Zhao, Ling Hou, Qin Ning, Xiaoping Luo
BACKGROUND AND AIMS: A novel bioactive peptide, mitochondrial-derived peptide (MOTS-c), has recently attracted attention as a potential prevention or therapeutic option for obesity and type 2 diabetes mellitus (T2DM). MOTS-c profiles have not yet been reported in human obesity and T2DM. We aimed to determine circulating MOTS-c levels in obesity and explore the association between MOTS-c levels and various metabolic parameters. METHODS: In this case-control study, 40 obese children and adolescents (27 males) and 57 controls (40 males) were recruited in the Hubei Province of China in 2017...
April 25, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29691951/physiotherapy-based-on-problem-solving-in-upper-limb-function-and-neuroplasticity-in-chronic-stroke-patients-a-case-series
#3
Raquel Carvalho, Elsa Azevedo, Paulo Marques, Nuno Dias, João José Cerqueira
RATIONALE, AIMS, AND OBJECTIVES: Upper limb recovery is one of the main concerns of stroke neurorehabilitation. Neuroplasticity might underlie such recovery, particularly in the chronic phase. The purpose of this study was to assess the effect of physiotherapy based on problem-solving in recovering arm function in chronic stroke patients and explore its neuroplastic changes. METHODS: A small sample research design with a n of 3 using a pre-post test design was carried out...
April 25, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29691933/pcr-analysis-of-a-prescription-vegetarian-diet-and-use-in-three-dogs-with-cutaneous-adverse-food-reactions
#4
Erin E Aufox, Elizabeth R May, Linda A Frank, Stephen A Kania
BACKGROUND: Cutaneous adverse food reaction (CAFR) is diagnosed by performing an elimination diet trial utilizing prescription or home-cooked diets followed by provocative challenge. OBJECTIVES: To report findings of PCR analysis of a prescription vegetarian diet (RCV) for undeclared proteins of animal origin, as well as to describe its utilization for diagnosis and management of dogs suspected of having CAFR. ANIMALS: Three client-owned dogs...
April 24, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29691899/droplet-digital-pcr-for-bcr-abl-p210-detecting-of-cml-a-high-sensitive-method-of-the-minimal-residual-disease-disease-progression
#5
Wen-Jun Wang, Chao-Feng Zheng, Zhuang Liu, Yan-Hong Tan, Xiu-Hua Chen, Bin-Liang Zhao, Guo-Xia Li, Zhi-Fang Xu, Fang-Gang Ren, Yao-Fang Zhang, Jian-Mei Chang, Hong-Wei Wang
OBJECTIVE: The present study intended to establish a droplet digital PCR (dd-PCR) for monitoring minimal residual disease (MRD) in patients with BCR/ABL (P210)-positive CML, thereby achieving deep-level monitoring of tumor load and determining the efficacy for guided clinically individualized treatment. METHODS: Using dd-PCR and RT-qPCR, two cell suspensions were obtained from K562 cells and normal peripheral blood mononuclear cells by gradient dilution and were measured at the cellular level...
April 25, 2018: European Journal of Haematology
https://www.readbyqxmd.com/read/29691854/necropsy-findings-of-koalas-from-the-mount-lofty-ranges-population-in-south-australia
#6
K N Speight, P Hicks, C Graham, W Boardman, W G Breed, E Manthorpe, O Funnell, L Woolford
OBJECTIVE: This study reports necropsy findings of koalas from the Mount Lofty Ranges region in order to identify health threats to this mainland South Australian population. METHODS: Koalas from the Mount Lofty Ranges region (n = 85) that had died or been euthanased on welfare grounds were examined at necropsy during 2012-13 at the School of Animal and Veterinary Sciences, University of Adelaide. Disease findings, approximate age, sex and body condition of koalas were recorded...
May 2018: Australian Veterinary Journal
https://www.readbyqxmd.com/read/29691809/standardization-of-simple-auxiliary-method-beneficial-to-total-endoscopic-thyroidectomy-on-patients-with-ptc-based-on-retrospective-study-of-356-cases
#7
Shouyi Yan, Wenxin Zhao, Bo Wang, Liyong Zhang
OBJECTIVE: Total endoscopic thyroidectomy (TET) is paid increasing attention to by patients, especially those with thyroid carcinoma. The aim of this study is to evaluate the clinic feasibility of standardization of simple auxiliary method (SOSAM) involved in operating bed adjustment, location of skin traction points and thyroid retractor points for the TET via bilateral breast approach. METHODS: A retrospective study was performed on 356 patients with thyroid carcinoma, who had undergone the TET...
April 24, 2018: Endocrine
https://www.readbyqxmd.com/read/29691782/cost-effectiveness-of-aspirin-adherence-for-secondary-prevention-of-cardiovascular-events
#8
Laurence M Djatche, Stefan Varga, Robert D Lieberthal
BACKGROUND: Suboptimal adherence to aspirin therapy for secondary prevention of cardiovascular (CV) events is an important public health problem. Prior studies have demonstrated non-adherent patients are at higher risk of experiencing CV events. OBJECTIVES: This study aimed to estimate the clinical and economic outcomes of aspirin non-adherence in patients with a prior primary CV event. METHODS: We developed a Markov model to estimate the cost-effectiveness of aspirin adherence from a generic US managed care payer perspective over a 5-year time horizon...
April 24, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29691773/etelcalcetide-for-treating-secondary-hyperparathyroidism-an-evidence-review-group-evaluation-of-a-nice-single-technology-appraisal
#9
Micah Rose, Jonathan Shepherd, Petra Harris, Karen Pickett, Joanne Lord
The manufacturer of the calcimimetic drug etelcalcetide was invited to make an evidence submission as part of the National Institute for Health and Care Excellence (NICE) Single Technology Appraisal (STA) programme. Within this submission, they reported evidence on the clinical and cost effectiveness of etelcalcetide for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) on haemodialysis. The Southampton Health Technology Assessments Centre (SHTAC), part of the Wessex Institute at the University of Southampton, was the independent Evidence Review Group (ERG) commissioned to appraise the company's submission...
April 25, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29691755/my-patient-has-received-fluid-how-to-assess-its-efficacy-and-side-effects
#10
REVIEW
Xavier Monnet, Jean-Louis Teboul
Many efforts have been made to predict, before giving fluid, whether it will increase cardiac output. Nevertheless, after fluid administration, it is also essential to assess the therapeutic efficacy and to look for possible adverse effects. Like for any drug, this step should not be missed. Basically, volume expansion is aimed at improving tissue oxygenation and organ function. To assess this final result, clinical signs are often unhelpful. The increase in urine output in case of acute kidney injury is a poor marker of the kidney perfusion improvement...
April 24, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29691736/metastatic-melanoma-to-the-colon-rectum-and-anus-a-50-year-experience
#11
Jin-Soo Park, Kheng-Seong Ng, Robyn P M Saw, John F Thompson, Christopher J Young
BACKGROUND: Melanoma metastatic to the large bowel (colon, rectum, and anus) is rarely diagnosed, with more than 95% of large bowel metastases identified post-mortem. The incidence, natural history, and survival rates of patients with large bowel melanoma metastases are poorly documented in the literature. OBJECTIVE: This study aimed to identify the incidence, clinical characteristics, and survival of patients with large bowel melanoma metastases. METHODS: A review was undertaken of all patients with melanoma treated over a 50-year period (1964-2014) at a tertiary referral center...
April 24, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29691681/the-impact-of-the-ryan-white-hiv-aids-medical-case-management-program-on-hiv-clinical-outcomes-a-longitudinal-study
#12
Julia D López, Enbal Shacham, Tawnya Brown
Medical case management (MCM) is a core medical service in The Ryan White HIV/AIDS Program and aims to provide treatment and care for people living with HIV/AIDS by engaging, identifying and eliminating barriers to HIV care. Little research has examined the impact of this intervention; therefore, the purpose of this study was to examine the how MCM affects HIV clinical outcomes. The study took place at a midwestern, outpatient infectious diseases clinic. This study utilized a longitudinal, retrospective study design to analyze to the impact of MCM engagement on HIV clinical outcomes (viral loads, CD4 counts) from 2009 to 2015 as a time-varying predictor...
April 24, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29691679/the-impact-of-next-generation-sequencing-on-the-diagnosis-of-pediatric-onset-hereditary-spastic-paraplegias-new-genotype-phenotype-correlations-for-rare-hsp-related-genes
#13
Lorena Travaglini, Chiara Aiello, Fabrizia Stregapede, Adele D'Amico, Viola Alesi, Andrea Ciolfi, Alessandro Bruselles, Michela Catteruccia, Simone Pizzi, Ginevra Zanni, Sara Loddo, Sabina Barresi, Gessica Vasco, Marco Tartaglia, Enrico Bertini, Francesco Nicita
Hereditary spastic paraplegias (HSP) are clinical and genetic heterogeneous diseases with more than 80 disease genes identified thus far. Studies on large cohorts of HSP patients showed that, by means of current technologies, the percentage of genetically solved cases is close to 50%. Notably, the percentage of molecularly confirmed diagnoses decreases significantly in sporadic patients. To describe our diagnostic molecular genetic approach on patients with pediatric-onset pure and complex HSP, 47 subjects with HSP underwent molecular screening of 113 known and candidate disease genes by targeted capture and massively parallel sequencing...
April 24, 2018: Neurogenetics
https://www.readbyqxmd.com/read/29691651/long-term-results-of-laparoscopic-liver-resection-for-the-primary-treatment-of-hepatocellular-carcinoma-role-of-the-surgeon-in-anatomical-resection
#14
Woo-Hyoung Kang, Ki-Hun Kim, Dong-Hwan Jung, Gil-Chun Park, Seok-Hwan Kim, Hwui-Dong Cho, Sung-Gyu Lee
BACKGROUND: Liver resection is a potentially curative therapy for hepatocellular carcinoma (HCC). LLR is a newly developed and safe technique associated with shorter hospital stay, less pain, better cosmetic outcomes, and similar complication rates as open surgery; however, data on its long-term outcomes remain scarce. METHODS: We retrospectively examined the clinical and follow-up data of 234 patients who underwent LLR (performed by a single surgeon in all cases) for the primary treatment of HCC between July 2007 and December 2015 at Asan Medical Center...
April 24, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29691618/patients-with-an-achilles-tendon-re-rupture-have-long-term-functional-deficits-in-function-and-worse-patient-reported-outcome-than-primary-ruptures
#15
Olof Westin, Katarina Nilsson Helander, Karin Grävare Silbernagel, Kristian Samuelsson, Annelie Brorsson, Jón Karlsson
PURPOSE: The aim of this study was to perform a long-term follow-up of patients treated for an Achilles tendon re-rupture, using established outcome measurements for tendon structure, lower extremity function and symptoms, and to compare the results with those for the uninjured side. A secondary aim was to compare the outcome with that of patients treated for primary ruptures. The hypotheses were that patients with a re-rupture recover well, and have similar long-term outcome as primary ruptures...
April 24, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29691614/catheter-embolization-of-type-ii-congenital-extrahepatic-portosystemic-shunt-with-hematochezia-a-case-series-and-review-of-the-literature
#16
Bo Zhang, Ke-Tong Wu, Lin Li, Hai-Yang Lai
Hematochezia is a rare clinical presentation of congenital extrahepatic portosystemic shunt (CEPS). We describe a series of three patients with type II CEPS presenting as hematochezia that were treated by catheter embolization, followed by a brief review of published articles. Hematochezia of the patients was due to the giant inferior mesenteric vein, superior rectal vein and colonic varices. The catheter embolization was successfully accomplished in all of the patients. After a mean follow-up of 27 months, no serious adverse effects were observed...
April 24, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29691600/a-proinflammatory-cd4-t-cell-phenotype-in-gestational-diabetes-mellitus
#17
Angela Sheu, Yixian Chan, Angela Ferguson, Mohammad B Bakhtyari, Wendy Hawke, Chris White, Yuk Fun Chan, Patrick J Bertolino, Heng G Woon, Umaimainthan Palendira, Frederic Sierro, Sue Mei Lau
AIMS/HYPOTHESIS: Numerous adaptations of the maternal immune system are necessary during pregnancy to maintain immunological tolerance to the semi-allogeneic fetus. Several complications of pregnancy have been associated with dysregulation of these adaptive mechanisms. While gestational diabetes mellitus (GDM) has been associated with upregulation of circulating inflammatory factors linked to innate immunity, polarisation of the adaptive immune system has not been extensively characterised in this condition...
April 24, 2018: Diabetologia
https://www.readbyqxmd.com/read/29691571/-case-based-learning-based-on-cbct-software-in-clinical-teaching-of-oral-and-maxillofacial-radiology
#18
Ling Zhu, Xia Cao, Xiao-Feng Tao
PURPOSE: To compare the teaching result of case-based learning based on cone-beam CT (CBCT) software and traditional pantomography. METHODS: Thirty-eight interns (7-year programme) of grade 2011 from College of Stomatology, Shanghai Jiao Tong University were enrolled. The inner diameter of the nasopalatine ducts (A), the length of upper canine's pulp cavity (B), the length between root furcation of upper first molar and the maxillary sinus (C), the length between the root of lower wisdom tooth and the inferior alveolar nerve (D) were measured on pantomographic films and CBCT in the same case...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29691569/-comparative-study-of-pain-releasing-effect-of-two-approaches-to-acute-pulpitis-in-the-night-emergency
#19
Jian Liu, Cun-Shan Shi
PURPOSE: To compare the clinical effect of 2 methods for acute pulpitis in the night emergency. METHODS: Two hundred and twenty-three patients with acute pulpitis were randomly divided into experimental group (107 cases) and control group (109 cases). Patients in the experimental group was enclosed formaldehyde cresol (FC) with CAVITON-GC after removal of crown pulp, while patients in the control group was treated with open drainage. Pain releasing effect was evaluated and analyzed 2 days after treatment.The data were analysed by t test and χ2 test with SPSS19...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29691561/-evaluation-of-nutrition-risk-and-analysis-of-relative-factors-of-patients-with-oral-and-maxillofacial-cancer
#20
Ying Liu, Wu-Long Jin
PURPOSE: To evaluate the potential nutrition risk and analyze relative factors in patients with oral and maxillofacial cancer, and explore the treatment method of nutrition risk. METHODS: Eighty eight patients with oral and maxillofacial cancer were included in the present study. Their age, height, weight, clinical classification, level of hemoglobin、albumin and prealbumin,present treatment were recorded and patients' body weight index (BMI) was calculated and scored based on a table of nutrition risk evaluation...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
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