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https://www.readbyqxmd.com/read/29458219/clinical-endocrine-and-imaging-characteristics-of-patients-with-primary-hypophysitis
#1
Anna Angelousi, Carolina Cohen, Soledad Sosa, Karina Danilowicz, Lina Papanastasiou, Marina Tsoli, Aparna Pal, Georgios Piaditis, Ashley Grossman, Gregory Kaltsas
Primary hypophysitis (PH) is a rare disease with a poorly-defined natural history. Our aim was to characterise patients with PH at presentation and during prolonged follow-up. Observational retrospective study of 22 patients was conducted from 3 centres. In 14 patients, PH was confirmed histologically and in the remaining 8 clinically, after excluding secondary causes of hypophysitis. All patients had hormonal and imaging investigations before any treatment. Median follow up was 48 months (25-75%: 3-60). There was a female predominance with a female/male ratio: 3...
February 19, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29458200/influence-of-treatment-modality-on-morbidity-and-mortality-in-periprosthetic-femoral-fracture-a-comparative-study-of-71-fractures-treated-by-internal-fixation-or-femoral-implant-revision
#2
S Cohen, X Flecher, S Parratte, M Ollivier, J N Argenson
INTRODUCTION: The incidence of periprosthetic femoral fracture is constantly increasing, with high associated morbidity and mortality. Surgical treatment is guided by the Vancouver classification, but the influence of type of treatment on morbidity and mortality has been little analyzed. The theoretic advantage of implant revision over internal fixation is that it should allow earlier weight-bearing, although the impact of this on morbidity and mortality and autonomy has not been demonstrated...
February 16, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29458192/magnetic-resonance-imaging-safety-in-non-conditional-pacemaker-and-defibrillator-recipients-a-meta-analysis-and-systematic-review
#3
Anand D Shah, Mike A Morris, David S Hirsh, Megan Warnock, Yijian Huang, Mike Mollerus, Faisal M Merchant, Anshul M Patel, David B Delurgio, Adarsh U Patel, Michael H Hoskins, Mikhael F El Chami, Angel R Leon, Jonathan J Langberg, Michael S Lloyd
BACKGROUND: Recommendations regarding performance of MRI in non-MRI conditional pacemaker and defibrillator recipients are evolving. Previous studies suggest low adverse event rates with MRI in non-conditional CIED recipients, but low power limits optimal characterization of risk. OBJECTIVE: In order to improve power, a systematic review and meta-analysis was performed to characterize the clinical risk associated with MRI in CIED recipients. METHODS: PUBMED and CINAHL indexed articles from 1990-2017 were queried...
February 16, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29458132/therapeutic-drug-monitoring-in-treatment-experienced-hiv-infected-patients-receiving-darunavir-based-salvage-regimens-a-case-series
#4
Sébastien Landry, Chi-Nan Chen, Nimish Patel, Alice Tseng, Richard G Lalonde, Denis Thibeault, Steven Sanche, Nancy L Sheehan
Therapeutic drug monitoring (TDM) constitutes a compelling approach for the optimization of antiretroviral therapy in treatment-experienced HIV-1 patients. While various inhibitory indices have been proposed to predict virologic outcome, there is a lack of consensus on the clinical value of TDM. Here, we report the comparative results of TDM in 14 HIV-1-infected patients who had previously received at least two different PI-based regimens and who initiated darunavir (DRV)-based salvage therapy. Pharmacokinetic/pharmacodynamics (PK/PD) parameters were calculated for each subject...
February 16, 2018: Antiviral Research
https://www.readbyqxmd.com/read/29458065/nosocomial-ventriculitis-caused-by-a-meticillin-and-linezolid-resistant-clone-of-staphylococcus-epidermidis-in-neurosurgical-patients
#5
Carlos Rodríguez-Lucas, Javier Fernández, José Antonio Boga, Lucia López-Amor, Lorena Forcelledo, Eva Lázaro-López, M Rosario Rodicio
BACKGROUND: Post-neurosurgical ventriculitis is mainly caused by coagulase-negative staphylococci. The rate of linezolid resistant S. epidermidis (LRSE) is increasing worldwide. AIMS: To report clinical and microbiological data from a series of ventriculitis cases caused by LRSE in a Spanish hospital between 2013 and 2016. METHODS: LRSE ventriculitis cases were retrospectively reviewed in a Spanish hospital during a four-year period. Clinical/epidemiological data of the infected patients were reviewed, the isolates involved were typed by PFGE and MLST, and the molecular basis of linezolid resistance was determined...
February 16, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29457989/propylthiouracil-induced-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis-mimicking-kawasaki-disease
#6
Yoshihiro Aoki, Katsuhiko Kitazawa, Hironobu Kobayashi
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is rare in children and is characterised as necrotising vasculitis predominantly affecting small and medium-sized vessels. Propylthiouracil (PTU), an antithyroid drug, has been implicated in drug-induced AAV. In contrast, Kawasaki disease (KD) is a common systemic vasculitis, typically observed in children, which affects the medium-sized vessels, including the coronary arteries. An 11-year-old girl who developed AAV while receiving PTU therapy for Graves' disease is described...
February 19, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29457935/customized-titanium-lattice-structure-in-three-dimensional-alveolar-defect-an-initial-case-letter
#7
Marcus Seiler, Peer W Kaemmerer, Michael Peetz, Amely Gundula Hartmann
The aim of this initial case report was to provide a new protocol for the clinical application of a patient-specific titanium lattice structure (Yxoss CBR®, ReOSS, Filderstadt, Germany) for customized bone regeneration. To obtain a 3-dimensional reconstruction of a posterior mandible segment in a 61-year-old woman, a patient-specific titanium customized lattice structure was used. As graft material autogenous bone tissue mixed with xenogenic alloplastic material (Bio Oss®, Geistlich Pharma, Wolhusen, Switzerland) was obtained for reconstruction...
February 19, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29457702/short-time-window-for-transmissibility-of-african-swine-fever-virus-from-a-contaminated-environment
#8
A S Olesen, L Lohse, A Boklund, T Halasa, G J Belsham, T B Rasmussen, A Bøtner
Since the introduction of African swine fever virus (ASFV) into the Baltic states and Poland in 2014, the disease has continued to spread within these regions. In 2017, the virus spread further west and the first cases of disease were reported in the Czech Republic and Romania, in wild boar and domestic pigs, respectively. To control further spread, knowledge of different modes of transmission, including indirect transmission via a contaminated environment, is crucial. Up until now, such an indirect mode of transmission has not been demonstrated...
February 19, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29457589/short-term-efficacy-of-pipeline-embolization-device-for-treating-complex-intracranial-aneurysms
#9
NiZaMiDingJiang ReXiaTi, ReXiDan AiKeReMu, KaHeErMan KaDeEr, Yan-Dong Fan, Zhao-Hai Feng, Kai Wang, TeWuErBaTi SuErTanNiYa, Tao-Tao Dou, Hai-Qiang Wu, MaiMaiTiLi AiSha, Xiao-Jiang Cheng
OBJECTIVE: To observe the short-term efficacy of Pipeline embolization divice (PED) for the treatment of complex intracranial aneurysms. METHODS: The clinical data of 29 consecutive patients with 32 intracranial aneurysms treated with PED between April 2015 to September 2016 were analyzed retrospectively. There were 3 small aneurysm, 15 large aneurysms, 8 giant aneurysms, 5 fusiform ayneurysms and 1 recidivation. The vessels include 25 anterior circulation and 4 posterior circulation...
2018: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/29457585/training-nurses-in-a-competency-framework-to-support-adults-with-epilepsy-and-intellectual-disability-the-epaid-cluster-rct
#10
Howard Ring, James Howlett, Mark Pennington, Christopher Smith, Marcus Redley, Caroline Murphy, Roxanne Hook, Adam Platt, Nakita Gilbert, Elizabeth Jones, Joanna Kelly, Angela Pullen, Adrian Mander, Cam Donaldson, Simon Rowe, James Wason, Fiona Irvine
BACKGROUND: People with an intellectual (learning) disability (ID) and epilepsy have an increased seizure frequency, higher frequencies of multiple antiepileptic drug (AED) use and side effects, higher treatment costs, higher mortality rates and more behavioural problems than the rest of the population with epilepsy. The introduction of nurse-led care may lead to improvements in outcome for those with an ID and epilepsy; however, this has not been tested in a definitive clinical trial...
February 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29457533/pyogenic-infection-of-the-hip-joint-as-a-complication-of-a-femoral-artery-vascular-access-for-percutaneous-coronary-intervention
#11
Jaroslaw Ucieklak, Robert Michał Proczka
A rare case of clinical complication following a percutaneous coronary intervention is presented. A femoral vascular access was chosen to treat a coronary lesion with a stent implantation. This femoral vascular access, however, resulted in a pyogenic infection of the ipsilateral hip joint that was not properly diagnosed for an extended post-interventional period. The hip joint completely deteriorated before its underlying cause was identified. This case report illustrates the importance of recognizing potential endovascular complications independently of their frequency...
February 1, 2018: Therapeutic Advances in Cardiovascular Disease
https://www.readbyqxmd.com/read/29457486/case-report-of-empagliflozin-induced-cutaneous-polyarteritis-nodosa
#12
Derek To, Scott Bradshaw, Jennifer Lipson
Polyarteritis nodosa (PAN) is a rare vasculitis affecting medium-sized vessels. Cutaneous PAN is a clinical variant, and we report the first case of empagliflozin-induced cutaneous PAN in a 69-year-old man. After starting empagliflozin, the patient presented with tender subcutaneous nodules on his legs, which showed a medium-sized vessel vasculitis on histopathology. Upon cessation of this medication, he had full resolution of these nodules. This case illustrates that empagliflozin can induce cutaneous PAN, and further attention to this medication's association with cutaneous PAN is warranted...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29457439/-antero-medial-incision-of-knee-joint-for-the-treatment-of-intercondylar-fracture-of-femur
#13
Zi-Fei Yin, Bin-Feng Sun, Xiao-Hai Yang, Qing Wang, Ping-Kang Qian, Xiao-Feng Wu, Feng Xu
OBJECTIVE: To explore the clinical effect of antero-medial incision of knee joint in treating intercondylar fracture of femur. METHODS: From September 2012 to March 2015, 24 patients with intercondylar fracture of femur were selected, including 17 males and 7 females, aged from 20 to 65 years old with an average of(38.3±9.5) years old. Among them, 12 cases were caused by traffic accident, 8 cases were caused by falling injury and 4 cases were caused by falling down...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457438/-ct-and-mri-manifestation-of-primary-spinal-large-b-cell-lymphoma
#14
Ping Tian, Kai Jiang, Zhi-Qiang Cai, Yong-Tao Wang, Sheng-de Deng
OBJECTIVE: To investigate CT and MRI characteristics of primary spinal large B cell lymphoma. METHODS: CT and MRI data of 23 patients with primary spinal large B cell lymphoma confirmed by histopathology were retrospectively analyzed from March 2011 to August 2015. Among them, including 14 males and 9 females aged from 28 to 70 years old with an average of 53.4 years old. The clinical manifestation mainly focus on pain around spinal and minority peripheral nerve symptom...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457437/-clinical-application-value-of-mri-on-malignant-fibrous-histiocytoma-in-soft-tissue
#15
Wan-Li Xu, Xiao Wu, Hai-Feng Qian, Dong Liu
OBJECTIVE: To investigate imaging manifestation and clinical application of MRI on malignant fibrous histiocytoma (MFH) in soft tissue. METHODS: Imaging and pathological data of 16 patients with malignant fibrous histiocytoma (MFH) in soft tissue confirmed by surgery and pathology were retrospectively analyzed from January 2009 to August 2016. There were 9 males and 7 females, aged from 34 to 67 years old with an average of 52 years. The courses of disease ranged from 5 to 48 months with an average of 27 months...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457436/-clinical-application-of-tibial-composite-saphenous-nervetissue-flap-for-the-treatment-of-traumatic-bone-skin-defect-of-leg
#16
Zhi-Wei Zhao, Wen-Jing Liu, Zhu-Qing Zha, Yan-Feng Li, Hui-Jun Fan
OBJECTIVE: To investigate the effect of tibial composite saphenous nerve tissue flap in repairing traumatic bone-skin defect of leg. METHODS: From February 2009 to May 2015, 23 patients with focile skin defect caused by trauma were treated, including 18 males and 5 females, aged from 8 to 59 years old with an average age of 35.6 years old. Length of tibia bone cortex defect ranged from 4 to 12 cm, width ranged from 2 to 2.5cm, skin defect ranged from 8 cm× 3 cm to 18 cm× 11 cm, all the wound surfaces had purulent exudation...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457435/-repair-soft-tissue-defect-in-forefoot-with-reversed-lateral-soleus-muscle-flap
#17
Gong-Lin Zhang, Ping Zhen, Ke-Ming Chen, Lai-Xu Zhao, Jun-Lin Yang, Jan-Hua Zhou, Qin-Yi Xue
OBJECTIVE: To summarize clinical application results of repair soft tissue defect in forefoot with a reversed lateral soleus muscle flap on peroneal artery pedicle. METHODS: From January 2005 to January 2013, 8 patients with soft-tissue defect on forefoot were underwent reconstruction with a reversed lateral soleus muscle flap on peroneal artery pedicle. There were 6 males and 2 female, aged from 16 to 48 years with an average of 26.8 years old. The reversed lateral soleus muscle flap was transposed to the forefoot defect area, then immediate coverage of the muscle flaps were performed by a meshed split-thickness free skin graft...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457431/-efficacy-analysis-on-hip-replacement-for-hip-joint-diseases-with-parkinson-disease
#18
Qi-Cai Sun, Xuan-Liang Ru, Yan-Fei Xia, Xiao-Li Liu, Bai-Shan Song, Song Qiao, Shi-Gui Yan, Xiang-Hua Wang
OBJECTIVE: To explore clinical efficacy of hip replacement for hip-joint diseases with Parkinson disease. METHODS: From December 2011 to December 2016, 18 patients with hip-joint diseases with Parkinson disease treated by hip replacement, including 8 males and 10 females aged from 59 to 87 years old with an average of 71 years old. Among them, 3 cases were developmental dysplasia of hip, 3 cases were femoral head necrosis and 12 cases were femoral neck fracture...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457430/-clinical-effect-of-superselective-arterial-embolization-for-the-treatment-of-massive-haemorrhage-from-pelvic-fracture
#19
Zheng-Qiu Lin, Xiu-Zhi Ye, Wei-Liang Wang, Guo-Qing Zhu, Bing-Ju Xie, Liang-le Liu
OBJECTIVE: To investigate feasibility and curative effect of superselective arterial embolization for the treatment of massive haemorrhage from pelvic fracture. METHODS: From March 2008 to February 2016, clinical data of 65 patients with massive haemorrhage from pelvic fracture were collected and analyzed, and patients were divided into non-embolic and embolic group according to whether perform vascular thrombosis. Thirty-three patients were in non-embolic group including 26 males and 7 females aged from 21 to 64 years old with an average of(39...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457429/-stiletto-needle-and-needle-knife-for-influence-of-gravity-index-in-treating-knee-osteoarthritis
#20
Li-Jun Gu, Bin Zhang, Wen-Hua Li, Yan Tang, Fu-Hui Dong
OBJECTIVE: To explore stiletto needle and needle-knife for influence of double sufficient weight in treating knee osteoarthritis patients. METHODS: One hundred and thirteen early and medium term knee osteoarthritis patients were randomly divided into three groups, including stiletto needle group(38 cases), needle-knife group (38 cases) and voltaren group (37 cases). In stiletto needle group, there were 13 males and 25 females with an average of(55.87±7.72) years old, treated by stiletto needle once a week, and 2 weeks were a course; there were 11 males and 27 females in needle-knife group with an average of(57...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
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