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https://www.readbyqxmd.com/read/28432937/subantibiotic-dose-of-azithromycin-attenuates-alveolar-bone-destruction-and-improves-trabecular-microarchitectures-in-a-rat-model-of-experimental-periodontitis-a-study-using-micro-computed-tomography
#1
Hye-Shin Park, Yong Sun Lee, Eun-Young Choi, Jeom-Il Choi, In Soon Choi, Sung-Jo Kim
Azithromycin, a macrolide antibiotic, has anti-inflammatory and immunomodulatory activities apart from its antibacterial properties. In this study, we examined the efficacy of subantibiotic dose of azithromycin on ligature-induced periodontitis in rats using micro-computed tomography (micro-CT) imaging and bone parameter analysis. Male Sprague-Dawley rats were allocated to the following four groups: non-ligation (NL) group; ligation-only (L) group; ligation-plus-subantibiotic dose azithromycin (SA) group; and 4) ligation-plus-antibiotic dose azithromycin (AA) group...
April 19, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28432078/effect-of-4-5-6-7-8-tetrahydro-5-5-8-8-tetramethyl-2-naphthalenyl-carbamoyl-benzoic-acid-am80-on-alveolar-regeneration-in-adiponectin-deficient-mice-showing-a-chronic-obstructive-pulmonary-disease-like-pathophysiology
#2
Hitomi Sakai, Michiko Horiguchi, Tomomi Akita, Chihiro Ozawa, Mai Hirokawa, Yuki Oiso, Harumi Kumagai, Yoshito Takeda, Isao Tachibana, Norikazu Maeda, Chikamasa Yamashita
Chronic obstructive pulmonary disease (COPD) is an intractable pulmonary disease that causes widespread and irreversible alveolar collapse. Although COPD occurs worldwide, only symptomatic therapy is currently available. The objective of the present study was the development of therapeutic agents to eradicate COPD. Therefore, we focused on 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carbamoyl] benzoic acid (Am80), which is a derivative of all-trans retinoic acid. We evaluated the effects of Am80 on alveolar repair in a novel COPD model of adiponectin-deficient mice...
April 21, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/28431807/rhabdomyosarcoma-of-the-maxillofacial-region-in-children-and-adolescents-report-of-9-cases-and-literature-review
#3
Ioannis Iatrou, Nadia Theologie-Lygidakis, Ourania Schoinohoriti, Fotis Tzermpos, Anna-Maria Vessala
OBJECTIVE: To review clinical presentation, histology, treatment and survival for pediatric maxillofacial rhabdomyosarcoma (RMS) and evaluate the role of surgical treatment. STUDY DESIGN: Retrospective analysis of medical charts. METHODS: Files of patients, treated for primary maxillofacial RMS from 1997 to 2016, were examined for clinical presentation, staging, histology, treatment protocol and complications, recurrence and final outcome...
March 23, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28429487/effect-of-orthodontic-treatment-on-the-periodontal-tissues
#4
REVIEW
Joseph S Antoun, Li Mei, Kelsi Gibbs, Mauro Farella
Reduced periodontal support is a challenge that clinicians often face during rehabilitation of compromised dentition. The close and intricate relationship between the periodontal tissues and the processes of tooth movement suggest that adjunct orthodontic therapy may play an important role in overcoming these problems. On the other hand, excessive movement of teeth beyond the anatomic boundaries of the alveolar process is commonly believed to contribute to further destruction of the periodontal tissues. This review evaluates the clinical effects of various orthodontic tooth movements on the surrounding periodontal soft tissues and alveolar bone...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28429477/the-emerging-role-of-maxillofacial-radiology-in-the-diagnosis-and-management-of-patients-with-complex-periodontitis
#5
REVIEW
William C Scarfe, Bruno Azevedo, Lucas R Pinheiro, Menik Priaminiarti, Marcelo A O Sales
Contemporary periodontal therapy has evolved to become more interdisciplinary and increasingly involves more complex treatments, including bone and soft-tissue regenerative procedures. Therapeutic options require an imaging modality or combination of techniques that are capable of providing a diagnostic osseous baseline and facilitating quantification of smaller increments of bony change, both loss and additive, which are comparable over time. Intra-oral and panoramic radiography are the modalities most commonly used to identify the location, quantify the amount and the pattern of alveolar bone loss and determine response to therapy...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28429277/primary-ewing-sarcoma-primitive-neuroectodermal-tumor-of-the-kidney-a-clinicopathologic-study-of-23-cases
#6
Paari Murugan, Priya Rao, Pheroze Tamboli, Bogdan Czerniak, Charles C Guo
Primary Ewing sarcoma / primitive neuroectodermal tumor (ES) of the kidney is a rare neoplasm with limited clinicopathologic data. We report 23 such cases with no history of ES elsewhere in the body. The patients included 13 male and 10 female, aged 8-70 years (mean, 31 years). The average tumor size was 11.7 cm (range, 5-20 cm). Microscopic analysis showed predominantly lobular growth (n = 14), with focal papillary (n = 3), alveolar (n = 1), and hemangiopericytoma-like (n = 1) patterns. Several tumors (n = 11) exhibited robust mitotic activity (>10 mitoses/10 high-power fields)...
April 20, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28428651/utility-of-the-inspiratory-phase-in-high-resolution-computed-tomography-evaluations-of-pediatric-patients-with-bronchiolitis-obliterans-after-allogeneic-bone-marrow-transplant-reducing-patient-radiation-exposure
#7
Paulo Henrique Togni Filho, João Luiz Marin Casagrande, Henrique Manoel Lederman
OBJECTIVE: To evaluate the utility of the inspiratory phase in high-resolution computed tomography (HRCT) of the chest for the diagnosis of post-bone marrow transplantation bronchiolitis obliterans. MATERIALS AND METHODS: This was a retrospective, observational, cross-sectional study. We selected patients of either gender who underwent bone marrow transplantation and chest HRCT between March 1, 2002 and December 12, 2014. Ages ranged from 3 months to 20.7 years...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28422603/factors-responsible-for-unfavorable-dental-arch-relationship-in-non-syndromic-unilateral-cleft-lip-and-palate-children
#8
Sanjida Haque, Mohammad Khursheed Alam, Mohd Fadhli Khamis
OBJECTIVES: Multiple factors are whispered to be crucial cause of unfavourable dental arch relationship in cleft lip and palate (CLP).This study aims to evaluate the dental arch relationship of Bangladeshi children with non syndromic unilateral cleft lip and palate (UCLP) following cheiloplasty and palatoplasty. Also to explore the various congenital (UCLP type, UCLP side, family history of cleft, family history of class III) and environmental (cheiloplasty, palatoplasty) factors that affects dental arch relationship of UCLP patients...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28422326/alveolar-ridge-dimensional-changes-following-ridge-preservation-procedure-with-novel-devices-part-3-histological-analysis-in-non-human-primate-model
#9
Yingying Su, Jianxia Tang, Seiko Min, Lijia Guo, Yitong Liu, Yilin Xie, Jimin Xiong, Songlin Wang, Mauricio G Araújo, Homayoun H Zadeh, Yi Liu
OBJECTIVES: This study sought to investigate the histological changes following tooth extraction, ridge preservation and augmentation, using novel devices designed to obturate the oral orifice of extraction sockets (SocketKAP™) and provide structural support for sockets with defective bony walls (SocketKAGE™) in a non-human primate model. MATERIAL AND METHODS: Six Macaca fascicularis were imaged by cone beam computed tomography to register their preoperative alveolar bone...
April 19, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28421873/facial-alveolar-bone-width-at-the-first-and-second-maxillary-premolars-in-healthy-patients-a-cone-beam-computed-tomography-study
#10
Julio Rojo, José Viña, David Peñarrocha, Miguel Peñarrocha
The purpose was to analyze the thickness of the facial alveolar bone at the first and second maxillary premolars and determinate the percentage of premolars that reached 2 mm in width. A retrospective study analyzing cone beam computed tomography scans from the database of the Oral Surgery Unit of the University of Valencia was performed. Patients with periodontal disease, orthodontic treatment, absence among the first maxillary molars, premolars with endodontic treatment and/or prosthetic restorations were excluded...
April 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28419843/a-review-of-in-office-dynamic-image-navigation-for-extraction-of-complex-mandibular-third-molars
#11
Robert W Emery, Oxana Korj, Ravi Agarwal
PURPOSE: We performed a retrospective review of in-office removal of complex mandibular third molars with a dynamic image navigation system (DINS). MATERIALS AND METHODS: A retrospective review was conducted of cases completed from 2010 to 2014 by a single oral and maxillofacial surgeon. The average age of the patients was 47 years (range, 27 to 72 years). Extraction complexity was classified with Juodzbalys and Daugela's classification system. The included study cases had complexity scores of 9 or greater...
March 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28419499/periodontitis-changes-renal-structures-by-oxidative-stress-and-lipid-peroxidation
#12
Luiz Felipe de Carvalho França, Any Carolina Cardoso Guimarães Vasconcelos, Felipe Rodolfo Pereira da Silva, Even Herlany Pereira Alves, Joaquina Dos Santos Carvalho, David Di Lenardo, Luan Kelves Miranda de Souza, André Luiz Dos Reis Barbosa, Jand-Venes Rolim Medeiros, Jefferson Soares de Oliveira, Daniel Fernando Pereira Vasconcelos
OBJECTIVE: The aim of this study was to investigate whether experimental periodontitis cause changes to the renal tissues and imbalance in oxidative stress in kidneys. METHODS: Twenty-two female Wistar rats were separated into two groups: control and periodontitis. We assessed the following parameters: gingival bleeding index (GBI), tooth mobility, gum malondialdehyde (MDA), myeloperoxidase (MPO) activity, probing pocket depth (PPD), alveolar bone loss (ABL) for periodontal tissues; histomorphometric measures associated with renal corpuscle and histopathological aspects (evaluation of brush border) for kidneys; as also blood and urine biomarkers...
April 17, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28416313/changes-of-periodontal-parameters-after-apical-surgery-correlation-of-clinical-and-cone-beam-computed-tomographic-data
#13
Thomas von Arx, Linda Antonini, Giovanni E Salvi, Michael M Bornstein
INTRODUCTION: The purpose of this study was to evaluate the changes of the marginal periodontium 1 year after apical surgery. METHODS: Clinical and radiographic (cone-beam computed tomographic) examinations of 54 teeth treated with buccal access flaps for apical surgery were performed at baseline and after 1 year. Clinical assessment included measurements of probing pocket depth, the level of gingival margin (GM), and the width of keratinized tissue. Subsequently, the clinical attachment level (CAL) and the width of the attached gingiva were calculated...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28416159/new-finite-element-study-protocol-clinical-simulation-of-orthodontic-tooth-movement
#14
Antoine Bouton, Yohann Simon, Florent Goussard, Luciano Teresi, Vittorio Sansalone
The aim of this work was to model tooth movement in a more clinically-exact fashion, thanks to the use of new IT tools and imaging systems (cone-beam). Image segmentation and 3D reconstruction now enable us to model the anatomy realistically, while finite element (FE) analysis makes it possible to evaluate stresses and their distribution on the level of the tooth, the periodontal ligament (PDL) and the alveolar bone when a force is applied. The principle is to monitor tooth movement by obtaining optical impressions at each stage of treatment...
April 13, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28416096/treatment-outcomes-of-archwise-distraction-osteogenesis-in-mandibular-dentoalveolar-retrognathia-cases
#15
C Yöndem, Y B Acar, B C Şener, A N Erverdi
The aim of this study was to describe the treatment of class II malocclusion by sagittal advancement of the alveolar bone in the symphyseal area using an intraoral archwise distractor device and to determine the effects of this method on the dentoalveolar complex. Fifteen patients (10 female, five male) aged 16-20 years with a class II division 2 malocclusion, characterized by mandibular dentoalveolar retrusion and a prominent chin, underwent archwise alveolar distraction in the anterior mandible. Lateral cephalometric radiographs were obtained before distraction (T0), after 6 weeks of consolidation (T1), and after debonding (T2)...
April 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28413775/an-interesting-case-of-mycoplasma-pneumonia-associated-multisystem-involvement-and-diffuse-alveolar-hemorrhage
#16
Rashmi Mishra, Edison Cano, Sindhaghatta Venkatram, Gilda Diaz-Fuentes
Severe mycoplasma pneumonia is a rare entity with only 0.5-2% of cases having a fulminant course. We present a 74-year-old woman with hypertension, diabetes mellitus and remote history of marginal zone B-cell lymphoma admitted with abdominal pain and diarrhea of 1-2 days associated with body-aches, dyspnea, dry cough and weight loss for 2-3 weeks. On physical exam, she was febrile, tachypneic, tachycardic and hypoxic on room air. Chest examination revealed diffuse crackles and end-expiratory wheezes. Laboratory tests showed anemia, acute-on-chronic kidney injury and hyaline casts and epithelial cells in the urine analysis...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28410151/effect-of-ancestry-on-interleukin-10-haplotypes-in-chronic-periodontitis
#17
Camile de Barros Lopes, Regina Fatima Feio Barroso, Rommel Mario Rodrigues Burbano, Patricia Aleixo Garcia, Pablo Diego do Carmo Pinto, Ney Pereira Carneiro Dos Santos, Sidney Emanuel Batista Santos, Andrea Kely Campos Ribeiro-Dos-Santos
Chronic periodontitis is caused by an inflammatory reaction of the periodontal tissues and alveolar bone. This inflammation is caused by periodontopathic bacteria located in the subgingival biofilm, resulting in inflammatory reactions that may lead to loss of attachment. This tissue destruction is a consequence of host immune and inflammatory responses to specific periodontal pathogens and their metabolic products. Cytokines modulate the immune response, altering its efficiency in the competition against pathogens and increasing periodontal susceptibility...
June 1, 2017: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28409326/effect-of-corticision-on-orthodontic-tooth-movement-in-a-rat-model-as-assessed-by-rna-sequencing
#18
Qihui Gu, Shuyu Guo, Dongyue Wang, Tingting Zhou, Lin Wang, Zhendong Wang, Junqing Ma
Corticision is a common technique to accelerate orthodontic tooth movement; however, not much is known about the underlying mechanisms. In this study, we investigated the mechanism of alveolar tissue remodeling after corticision in a rat model of tooth movement (TM) by analyzing the differential transcriptome. A total of 36 male rats were equally divided into TM and TM with corticision (TM+C) groups. Alveolar bone response was examined using micro-computed tomography (micro-CT). Osteoclasts and osteoblasts were quantified on tartrate-resistant acid phosphatase (TRAP) and Goldner's trichrome staining...
April 13, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28407987/topographic-analysis-of-the-maxillary-premolars-relative-to-the-maxillary-sinus-and-the-alveolar-bone-using-cone-beam-computed-tomography
#19
Kazuhide Nishihara, Shin-Ichiro Yoshimine, Takahiro Goto, Kiyohide Ishihata, Ken-Ichi Kume, Takuya Yoshimura, Norifumi Nakamura, Akira Arasaki
OBJECTIVE: The purpose of the present study was to elucidate the anatomic characteristics of the maxillary premolars for the planning of dental treatment using cone beam computed tomography (CBCT). STUDY DESIGN: CBCT images were obtained for 150 maxillary premolars in 68 patients. The internal angle formed by the long axis of the maxillary premolars and the long axis of the alveolar bone was evaluated on the cross-sectional images. The vertical relationships between the maxillary premolars and the maxillary sinus were classified into 5 categories...
May 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28407514/age-estimation-from-structural-changes-of-teeth-and-buccal-alveolar-bone-level
#20
K K Koh, J S Tan, P Nambiar, Norliza Ibrahim, Sunil Mutalik, Muhammad Khan Asif
Forensic odontology plays a vital role in the identification and age estimation of unknown deceased individuals. The purpose of this study is to estimate the chronological age from Cone-Beam Computed Tomography (CBCT) images by measuring the buccal alveolar bone level (ABL) to the cemento-enamel junction and to investigate the possibility of employing the age-related structural changes of teeth as studied by Gustafson. In addition, this study will determine the forensic reliability of employing CBCT images as a technique for dental age estimation...
April 1, 2017: Journal of Forensic and Legal Medicine
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