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Fibromatosis

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https://www.readbyqxmd.com/read/29651852/current-treatment-options-of-dupuytren%C3%A2-s-disease
#1
J Kníže, J Miletín, A Nejedlý, M Chorvát, K Novotná, P Tichá, A Fibír, A Sukop, A Knížetová
Dupuytren's disease (fibromatosis of the palmar fascia, benign neoplastic fibromatosis, Dupuytren's contracture) is a disease characterized by growth and successive contracture of single parts of the palmar aponeurosis. This condition is known and has been treated for several centuries. In the advanced stages of the disease, it leads to significant limitation of hand function, resulting in reduced quality of life of the patient. Dupuytren's disease (DD) is a life-long disease with a variable course and a heterogeneous clinical presentation...
2018: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/29644533/systematic-review-of-clinical-outcomes-following-various-treatment-options-for-patients-with-extraabdominal-desmoid-tumors
#2
Kortnye Smith, Jayesh Desai, Smaro Lazarakis, David Gyorki
BACKGROUND: Desmoid tumors (DT) are rare clonal proliferations that arise from mesenchymal cells. These tumors do not metastasize but are locally aggressive, and their growth may lead to significant morbidity. Their clinical course is both variable and unpredictable; tumors may rapidly progress but in other instances remain stable or regress without intervention. AIMS: To examine current treatment of DT and assist with decision-making at time of presentation. METHODS: A literature search was conducted of MEDLINE and Cochrane databases for published studies (1995-July 2015) using the search terms fibromatosis aggressive, desmoid with drug therapy, radiation therapy, prevention and control, radiotherapy, surgery, and therapy...
April 11, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29643736/desmoid-fibromatosis-of-the-lower-abdominal-wall-in-irrua-nigeria
#3
Oluwafemi Olasupo Awe, Sylvester Eluehike
Desmoid fibromatosis (desmoid tumors) is rare tumors. It can occur as intra-abdominal, extraabdominal, or abdominal wall tumor depending on the site. The abdominal wall type is usually sporadic, but few have been associated with familial adenomatous polyposis. They are commonly seen in young females who are pregnant with a history of the previous cesarean section scar or within the 1st year of the last childbirth. There is an association between this tumor, presence of estrogen receptors, and abdominal trauma...
January 2018: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/29619843/current-concepts-review-plantar-fibromatosis
#4
Melissa Espert, Michael R Anderson, Judith F Baumhauer
No abstract text is available yet for this article.
April 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29603334/ultrasonography-of-plantar-fibromatosis-updated-case-series-review-of-the-literature-and-a-novel-descriptive-appearance-termed-the-comb-sign
#5
Blake E Cohen, Naveen S Murthy, Gavin A McKenzie
The purpose of this series is to review the appearance of plantar fibromatosis with high-resolution ultrasonography (US) and highlight a new imaging sign termed the "comb sign." A retrospective study was performed for patients with a clinical diagnosis of plantar fibromatosis. Charts of 43 patients (age range, 26-77 years; mean age, 54 years) were reviewed to gather patient demographics and symptoms. Several US characteristics were evaluated with emphasis on any new imaging features. A total of 57 plantar fibromas in 43 patients were examined...
March 30, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29564660/diagnostic-imaging-and-ceus-findings-in-a-rare-case-of-desmoid-type-fibromatosis-a-case-report
#6
REVIEW
Massimo Valentino, Mauro Liberatore, Fabrizio Maghella, Valeria De Soccio, Carlo De Felice, Daniela Messineo, Francesco Maria Drudi
Desmoid-type fibromatosis (DF), also known as aggressive fibromatosis, is a locally aggressive benign fibroblastic neoplasm that can infiltrate or recur but cannot metastasize. It is rare, with an estimated annual incidence of two to four new cases per million people. Most DFs occur sporadically, but it may also be associated with the hereditary syndrome familial adenomatous polyposis. Treatment is necessary when the disease is symptomatic, especially in case of compression of critical structures. When possible, surgical resection is the treatment of choice; however, recurrence is common...
March 21, 2018: Journal of Ultrasound
https://www.readbyqxmd.com/read/29563740/sporadic-retroperitoneal-fibrosis-a-gentle-giant
#7
Pavan Sugoor, Amit Gupta, Shraddha Patkar, Bharat Rekhi, Mahesh Goel
Fibromatosis covers a broad spectrum of benign fibrous tissue proliferation and is characterized by slow growing, locally infiltrative growth pattern with a high propensity for local recurrence. We report on a case of multicentric fibromatosis originating from the retroperitoneal space and submandibular triangle, in an 18-year-old lady. Computed tomography revealed a retroperitoneal abdominopelvic tumor extending from the left sub-diaphragmatic space to the pelvic inlet which had enveloped the solid viscera in the left upper quadrant with a displaced celiac axis...
March 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29562221/assessment-of-physician-s-systemic-treatment-preferences-for-patients-with-advanced-desmoid-type-fibromatosis-experience-based-medicine-in-the-absence-of-high-level-evidence
#8
Patrick Schöffski, Annelies Requilé, Tom van Cann
No abstract text is available yet for this article.
March 23, 2018: Oncology Research and Treatment
https://www.readbyqxmd.com/read/29552447/omental-fibromatosis-treated-by-laparoscopic-wide-surgical-resection
#9
David Martin, Mirza Muradbegovic, Snezana Andrejevic-Blant, David Petermann, Luca Di Mare
The current report presents a case of an omental fibromatosis discovered incidentally in a 46-year-old woman with no particular medical history and few symptoms. A surgical biopsy was performed initially, and microscopic examination revealed myofibroblastic proliferation. After additional immunohistochemical and molecular analyses, omental fibromatosis was diagnosed. Omental fibromatosis, also called intra-abdominal desmoid, is a rare and benign tumour but can be locally aggressive. Majority of cases are asymptomatic, and difficult to diagnose based on clinical presentation and radiological investigation...
February 2018: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/29534358/-lipofibromatosis-a-clinicopathological-analysis-of-eight-cases
#10
Q Y Lao, M Sun, L Yu, J Wang
Objective: To investigate the clinicopathological characteristics and differential diagnosis of lipofibromatosis. Methods: The clinicopathological features and immunohistochemical profiles in 8 cases of lipofibromatosis diagnosed at Fudan University Shanghai Cancer Center from January 2008 to June 2017 were studied. Molecular analysis of β-catenin mutation by Sanger sequencing, NTKR1 and ETV6 rearrangements by FISH were performed. The follow up information was evaluated and the literature was reviewed. Results: There were 4 males and 4 females with a median age of 1...
March 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29534260/two-genetic-variants-associated-with-plantar-fascial-disorders
#11
Stuart K Kim, John P A Ioannidis, Marwa A Ahmed, Andrew L Avins, John P Kleimeyer, Michael Fredericson, Jason L Dragoo
Plantar fascial disorder is comprised of plantar fasciitis and plantar fibromatosis. Plantar fasciitis is the most common cause of heel pain, especially for athletes involved in running and jumping sports. Plantar fibromatosis is a rare fibrous hyperproliferation of the deep connective tissue of the foot. To identify genetic loci associated with plantar fascial disorders, a genome-wide association screen was performed using publically available data from the Research Program in Genes, Environment and Health including 21,624 cases of plantar fascial disorders and 80,879 controls...
March 13, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29517699/misdiagnosis-of-aggressive-fibromatosis-of-the-abdominal-wall-a-case-report-and-literature-review
#12
REVIEW
Xiaoxia Liu, Shan Zong, Yingli Cui, Ying Yue
RATIONALE: Aggressive fibromatosis (AF) of abdominal wall is also called desmoid tumor, ligament tumor, fibrous tissue tumor hyperplasia, tendon membrane fibroma or soft tissue ligament fibroma, etc. Aggressive fibromatosis of abdominal wall was first described by MacFarlane in 1832, and it was named for the first time by Muller according to its general appearance and texture in 1838. This disease has been mistaken for a benign lesions for a long time because when the cells were examined by pathology often show normal mitosis, and distant metastases are not found clinically, but actually the disease is locally invasive and shows a local invasive growth...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29507725/desmoid-fibromatosis-of-the-chest-wall
#13
QiHao Ong, Janice Wong, Sanjay Sinha, Nand Kejriwal
We report a case of desmoid fibromatosis of the chest wall. A 70-year-old woman was referred to our hospital with right shoulder blade pain and paresthesia over the right upper breast. Chest X-ray and computed tomography demonstrated a 5 cm right apical mass in the chest. Biopsy of the mass demonstrated features of desmoid fibromatosis. The patient subsequently underwent surgical resection of the mass and received adjuvant radiation therapy for microscopic positive margins. In conclusion, although desmoid tumour of the chest is rare, it is worth considering in the differential diagnoses of chest wall tumours...
May 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29501289/treatment-of-extensive-post-tonsillectomy-oropharyngeal-stenosis-secondary-to-fibromatosis
#14
Brian Chang, Jennifer F Ha, David Zopf
Aggressive fibromatosis is an uncommon, benign tumor of fibroblastic origin with high potential for local invasion. Less than a quarter of these lesions are located in the head and neck, and although extremely rare, associations have been demonstrated with physical trauma. We describe a unique case of oropharyngeal fibromatosis with traumaticetiology, managed successfully with surgical excision of the lesion with negative surgical margins. A 5-year old patient was found to have an aggressive fibromatosis causing oropharyngeal stenosis following tonsillectomy...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29487969/giant-fibroepithelial-polyp-of-the-thigh-and-retroperitoneal-fibromatosis-in-a-young-woman-a-rare-case
#15
Ruchi Gupta, Shuchi Smita, Ruchi Sinha, Neetu Sinha, Lakshmi Sinha
We present a case of 20-year-old woman who presented with a large pedunculated skin covered mass lesion arising from the left thigh, measuring 40 × 25 cm, with no history of pain or skin ulceration and a feeling of a lump with dragging pain in the left side of the abdomen for about 7 years. Subsequently, ultrasound, contrast-enhanced computed tomography, and magnetic resonance imaging of abdomen and left thigh region were carried out. The lesion was broad-based toward the left upper thigh with a central core of interspersed fat supplied by branches of the superficial and deep femoral arteries...
February 27, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29487630/fibromatosis-of-the-breast-mimicking-cancer-a-case-report
#16
Maria Carmela Grimaldi, Chiara Trentin, Roberto Lo Gullo, Enrico Cassano
Breast fibromatosis, also referred to as desmoid tumor or aggressive fibromatosis, is a very rare, locally aggressive disease that does not metastasize. Bilateral lesions are extremely rare and are found in only 4% of patients with breast fibromatosis. Tumor recurrence following surgery occurs in 18%-29% of patients, most often within the first 2 years after surgery. In this report, we discuss a case of breast fibromatosis, mimicking a breast carcinoma both clinically and radiologically, that presented clinically with dimpling of the skin of the left breast in a 31-year-old woman...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29485080/radiation-therapy-for-aggressive-fibromatosis-the-association-between-local-control-and-age
#17
James E Bates, Christopher G Morris, Nicole M Iovino, Michael Rutenberg, Robert A Zlotecki, C Parker Gibbs, Mark Scarborough, Daniel J Indelicato
PURPOSE: Radiation therapy (RT) is often used in the treatment of unresectable or recurrent aggressive fibromatosis (also known as desmoid tumor) typically with excellent local control. Prior reports have suggested that local control in pediatric patients with aggressive fibromatosis is poor. We aimed to report a long-term single-institution experience with the radiotherapeutic treatment of these tumors with a focus on age-dependent outcomes. METHODS AND MATERIALS: A total of 101 patients treated with RT for aggressive fibromatosis between 1975 and 2015 at a single institution were identified...
March 15, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29469067/histopathologic-review-of-400-biopsies-and-resection-specimens-of-trunk-and-extremity-based-soft-tissue-tumors
#18
R Badanale, B Rekhi, N A Jambhekar, A Gulia, J Bajpai, S Laskar, N Khanna, G Chinnaswamy, A Puri
AIMS: To review various pathologic parameters in diagnosed cases of trunk and extremity-based soft tissue tumors (STTs), in order to identify concordance rate between initial biopsy and resection specimen and discrepancies between initial and review diagnosis, by a specialist pathologist. MATERIALS AND METHODS: Over a 2-year-period, 400 retrospectively diagnosed STTs (553 specimens) including referral and "in-house" cases were studied. The reviewing specialist pathologist was blinded to the initial diagnoses...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29455674/aggressive-fibromatosis-in-the-infratemporal-fossa-presenting-as-trismus-a-case-report
#19
Sunil Munakomi
BACKGROUND: Here we report a very rare entity of an infratemporal region aggressive fibromatosis in a 23-year-old Tharu man who had presented with the symptoms of painless but progressive trismus. CASE PRESENTATION: We describe a case of aggressive fibromatosis in a 23-year-old Tharu man. Radiological imaging as well as an immunohistochemistry panel from a biopsy indicated a diagnosis of an aggressive fibromatosis. Since there was no aggravation in his trismus following surgery and because of his poor socioeconomic status, he was advised to attend regular follow-up visits without any adjuvant therapy...
February 19, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29439260/nephrocalcinosis-in-amelogenesis-imperfecta-caused-by-the-fam20a-mutation
#20
Mine Koruyucu, Figen Seymen, Genco Gencay, Koray Gencay, Elif Bahar Tuna, Teo Jeon Shin, Hong-Keun Hyun, Young-Jae Kim, Jung-Wook Kim
BACKGROUND/AIMS: Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the FAM20A gene result in amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether AI patients with known -FAM20A mutations also have nephrocalcinosis. METHODS: Complete oral and radiological examinations were performed for all participating family members...
February 13, 2018: Nephron
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