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https://www.readbyqxmd.com/read/28222493/mobilising-culture-against-domestic-violence-in-migrant-and-ethnic-communities-practitioner-perspectives-from-aotearoa-new-zealand
#1
Rachel Simon-Kumar, Priya A Kurian, Faith Young-Silcock, Nirmala Narasimhan
Studies on domestic violence in ethnic minority communities highlight that social norms, family structures and cultural practices are among the key triggers of violence against women. Not surprisingly, most anti-violence interventions in these communities aim to redeem women from the oppressive features of these cultures. More recently, however, emergent scholarship advocates mobilising, rather than erasing, culture within existing anti-violence strategies. This paper explores the nature of culturally informed interventions used by front-line workers...
February 21, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28222167/emergence-and-development-of-gut-motility-in-the-chicken-embryo
#2
N R Chevalier, V Fleury, S Dufour, V Proux-Gillardeaux, A Asnacios
The gastrointestinal tract transports the food bolus by peristalsis. Gut motility starts at an early age in the developing embryo, well before it is required for nutrition of the organism. We present a comprehensive kinematic study of the emergence and physiological development of gut motility in all regions of the lower digestive tract of the chicken embryo from embryonic days E5 through E9. We characterized motility emergence time, propagation patterns, speed, frequency and amplitude of peristalsis waves...
2017: PloS One
https://www.readbyqxmd.com/read/28222091/perceived-benefits-and-barriers-of-cervical-cancer-screening-among-chinese-american-women
#3
Wei-Chen Tung, Minggen Lu, Michelle Granner
PURPOSE/OBJECTIVES: To explore the perceived benefits and barriers to cervical cancer screening among Chinese American women using stages of the Transtheoretical Model of Change.
. DESIGN: Cross-sectional design with self-report surveys. 
. SETTING: Chinese communities (e.g., churches, supermarkets, restaurants) in Northern California and Northern Nevada. 
. SAMPLE: 121 Chinese women aged 21-65 years living in Northern California and Northern Nevada...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28222082/challenges-encountered-by-vietnamese-nurses-when-caring-for-patients-with-cancer
#4
Ly Thuy Nguyen, Lourdes Clemenceau Annoussamy, Virginia T LeBaron
Providing holistic care is acknowledged as central to providing quality care for patients with cancer, but providing competent nursing care consistent with these approaches remains a challenge for nurses in Vietnam. Obstacles for Vietnamese oncology nurses include their low status, the limited scope of nursing practice, work overload in a hierarchical system, and cultural beliefs that view death and dying as taboo. Additional research to support oncology nurses in Vietnam must acknowledge the merits of improving nursing education as an important strategy for enhancing nursing autonomy, quality of care, and outcomes for the increasing number of patients with cancer in low- and middle-income countries...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28221769/manipulation-of-the-precursor-supply-in-yeast-significantly-enhances-the-accumulation-of-prenylated-%C3%AE-carbolines
#5
Katja Backhaus, Lena Ludwig-Radtke, Xiulan Xie, Shu-Ming Li
The tryptophan derivative 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) is present in many plants and foods including fermentation products of the baker's yeast Saccharomyces cerevisiae. MTCA is formed from tryp-tophan and acetaldehyde via a Pictet-Spengler reaction. In this study, up to 9 mg/l of MTCA were detected as a mixture of (1S,3S) and (1R,3S) isomers in a ratio of 2.2:1 in Saccharomyces cerevisiae cultures. To the best of our knowledge, this is the first report on the presence of MTCA in laboratory baker's yeast cultures...
February 21, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28221713/reconfigurable-microscale-frameworks-from-concatenated-helices-with-controlled-chirality
#6
Seog-Jin Jeon, Ryan C Hayward
The utility of helical structures in driving motion of microorganisms and plants has inspired efforts to develop synthetic stimuli-responsive helical architectures for self-motile and shape-morphing systems. While several approaches to responsive helices based on hydrogels and liquid crystalline polymers have been reported, they have so far been limited to macroscopic (cm scale) dimensions, and have not been applied to concatenated helices with more than two segments. Here, a robust method for microfabrication of helices inspired by Bauhinia seedpods, based on trilayer samples consisting of rigid plastic stripes sandwiching a swellable temperature-responsive hydrogel, is reported and the formation of responsive shape-controlled frameworks from concatenated multiple helices (multihelices) with controlled chirality is demonstrated...
February 21, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28221101/identification-of-a-novel-epitope-in-the-c-terminus-of-hcv-e2-protein-that-induces-potent-and-cross-reactive-neutralizing-antibodies
#7
Soma Das, Ranajoy Mullick, Anuj Kumar, Himani Tandon, Mihika Bose, K Gouthamchandra, Madhavi Chandra, Bagepally Ravishankar, M N Khaja, Narayanaswamy Srinivasan, Saumitra Das, Shaila Melkote Subbarao, Anjali Anoop Karande
Hepatitis C virus (HCV) is a leading cause of chronic viral hepatitis, but an effective vaccine is still not available to prevent infection. Use of neutralizing antibodies could be a potential therapeutic option. In this study, presence of anti-HCV antibodies in HCV-infected patients' was assessed from 50 patients and examined for the presence of neutralizing antibodies using the 'hepatitis C virus like particles'. Antibodies from two samples exhibited significant inhibitory activity suggesting that these may neutralize viral infection...
February 3, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28220955/profiles-of-adolescent-religiousness-using-latent-profile-analysis-implications-for-psychopathology
#8
Gregory S Longo, Bethany C Bray, Jungmeen Kim-Spoon
Prior research has documented robust associations between adolescent religiousness/spirituality (R/S) and psychopathology outcomes including externalizing and internalizing symptomatology, yet no previous studies have examined these associations with adolescent R/S profiles using a person-centred approach. We examined whether there are identifiable subgroups characterized by unique multidimensional patterns of R/S experiences and how these experiences may be related to externalizing and internalizing symptomatology...
March 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/28220863/engineering-botulinum-neurotoxin-c1-as-a-molecular-vehicle-for-intra-neuronal-drug-delivery
#9
Edwin J Vazquez-Cintron, Phillip H Beske, Luis Tenezaca, Bao Q Tran, Jonathan M Oyler, Elliot J Glotfelty, Christopher A Angeles, Aurelia Syngkon, Jean Mukherjee, Suzanne R Kalb, Philip A Band, Patrick M McNutt, Charles B Shoemaker, Konstantin Ichtchenko
Botulinum neurotoxin (BoNT) binds to and internalizes its light chain into presynaptic compartments with exquisite specificity. While the native toxin is extremely lethal, bioengineering of BoNT has the potential to eliminate toxicity without disrupting neuron-specific targeting, thereby creating a molecular vehicle capable of delivering therapeutic cargo into the neuronal cytosol. Building upon previous work, we have developed an atoxic derivative (ad) of BoNT/C1 through rationally designed amino acid substitutions in the metalloprotease domain of wild type (wt) BoNT/C1...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28220590/biosynthesis-and-mass-spectral-fragmentation-pathways-of-13-c-and-15-n-labeled-cytochalasin-d-produced-by-xylaria-arbuscula
#10
Luciana da Silva Amaral, Taicia Pacheco Fill, Luiz Fernando Arruda Santos, Edson Rodrigues-Filho
The fungus Xylaria arbuscula was isolated as an endophyte from Cupressus lusitanica and has shown to be a prominent producer of cytochalasans, mainly cytochalasin C, D and Q. Cytochalasans comprise an important class of fungal secondary metabolites that have aroused attention due to their uncommon molecular structures and pronounced biological activities. Due to the few published studies on the ESI-MS/MS fragmentation of this important class of secondary metabolites, in the first part of our work we studied the cytochalasin D fragmentation pathways using an ESI-Q-ToF mass spectrometer coupled with liquid chromatography...
February 21, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28220518/describing-student-performance-a-comparison-among-clinical-preceptors-across-cultural-contexts
#11
Kerry Wilbur, Noha Hassaballa, Omaima S Mahmood, Emily K Black
CONTEXT: Health professional student evaluation during experiential training is notably subjective and assessor judgements may be affected by socio-cultural influences. OBJECTIVES: This study sought to explore how clinical preceptors in pharmacy conceptualise varying levels of student performance and to identify any contextual differences that may exist across different countries. METHODS: The qualitative research design employed semi-structured interviews...
February 20, 2017: Medical Education
https://www.readbyqxmd.com/read/28220459/-how-would-you-call-this-in-english-being-reflective-about-translations-in-international-cross-cultural-qualitative-research
#12
Esther Helmich, Sayra Cristancho, Laura Diachun, Lorelei Lingard
INTRODUCTION: Medical education researchers increasingly collaborate in international teams, collecting data in different languages and from different parts of the world, and then disseminating them in English-language journals. Although this requires an ever-present need to translate, it often occurs uncritically. With this paper we aim to enhance researchers' awareness and reflexivity regarding translations in qualitative research. METHODS: In an international study, we carried out interviews in both Dutch and English...
February 20, 2017: Perspectives on Medical Education
https://www.readbyqxmd.com/read/28220125/hgf-secreted-by-activated-kupffer-cells-induces-apoptosis-of-plasmodium-infected-hepatocytes
#13
Lígia Antunes Gonçalves, Joana Rodo, Lurdes Rodrigues-Duarte, Luciana Vieira de Moraes, Carlos Penha-Gonçalves
Malaria liver stage infection is an obligatory parasite development step and represents a population bottleneck in Plasmodium infections, providing an advantageous target for blocking parasite cycle progression. Parasite development inside hepatocytes implies a gross cellular insult evoking innate host responses to counteract intra-hepatocytic infection. Using primary hepatocyte cultures, we investigated the role of Kupffer cell-derived hepatocyte growth factor (HGF) in malaria liver stage infection. We found that Kupffer cells from Plasmodium-infected livers produced high levels of HGF, which trigger apoptosis of infected hepatocytes through a mitochondrial-independent apoptosis pathway...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28220113/diverse-plant-associated-pleosporalean-fungi-from-saline-areas-ecological-tolerance-and-nitrogen-status-dependent-effects-on-plant-growth
#14
Yuan Qin, Xueyu Pan, Christian Kubicek, Irina Druzhinina, Komal Chenthamara, Jessy Labbé, Zhilin Yuan
Similar to mycorrhizal mutualists, the rhizospheric and endophytic fungi are also considered to act as active regulators of host fitness (e.g., nutrition and stress tolerance). Despite considerable work in selected model systems, it is generally poorly understood how plant-associated fungi are structured in habitats with extreme conditions and to what extent they contribute to improved plant performance. Here, we investigate the community composition of root and seed-associated fungi from six halophytes growing in saline areas of China, and found that the pleosporalean taxa (Ascomycota) were most frequently isolated across samples...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28219292/a-manner-of-being-body-languages-of-socio-economic-development
#15
Alexandra Antohin
This article proposes to move forward analytical work on the human aspect of socio-economic development, by featuring how personal decisions about physical appearance in effect negotiate socio-ethnic positions and desired economic aims that arise from new technologies of living. By envisioning how the body can serve as a conduit of consciousness-making, tattoos work as one cultural practice that produces an interplay between traditional precedents and contemporary trends and permits reflecting on how the categorizations of rural/urban can behave as a dialectical medium for internal anxieties and debates regarding social transformation...
July 2016: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28217699/the-female-urinary-microbiota-urinary-health-and-common-urinary-disorders
#16
REVIEW
Linda Brubaker, Alan J Wolfe
This review provides the clinical context and updated information regarding the female urinary microbiota (FUM), a resident microbial community within the female bladder of many adult women. Microbial communities have variability and distinct characteristics in health, as well as during community disruption (dysbiosis). Information concerning characteristics of the FUM in health and disease is emerging. Sufficient data confirms that the microbes that compose the FUM are not contaminants and are cultivatable under appropriate conditions...
January 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28217575/working-as-a-family-physician-in-canada-and-portugal-how-different-is-it
#17
Ana Nunes Barata
BACKGROUND: The work of a family physician is quite different in each country, and if we consider different continents, differences are even more remarkable. Social and cultural contexts justify a particular organization, not only of the health-care system but also its providers as well. OBJECTIVES: By analyzing different health-care systems, new ideas may come about which may trigger positive changes in a health-care service to diminish healthcare disparities. METHODS: Description and comparison of the Primary Healthcare Service in Canada and Portugal...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28216383/large-scale-analysis-of-crispr-cas9-cell-cycle-knockouts-reveals-the-diversity-of-p53-dependent-responses-to-cell-cycle-defects
#18
Kara L McKinley, Iain M Cheeseman
Defining the genes that are essential for cellular proliferation is critical for understanding organismal development and identifying high-value targets for disease therapies. However, the requirements for cell-cycle progression in human cells remain incompletely understood. To elucidate the consequences of acute and chronic elimination of cell-cycle proteins, we generated and characterized inducible CRISPR/Cas9 knockout human cell lines targeting 209 genes involved in diverse cell-cycle processes. We performed single-cell microscopic analyses to systematically establish the effects of the knockouts on subcellular architecture...
February 9, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28216060/incidence-of-fever-in-labor-and-risk-of-neonatal-sepsis
#19
Craig V Towers, Angela Yates, Nikki Zite, Casey Smith, Lindsey Chernicky, Bobby Howard
BACKGROUND: The current recommendation regarding the management of a term newborn delivered of a mother with an intrapartum fever or a diagnosis of clinical chorioamnionitis is that the neonate should have baseline laboratory work drawn along with blood cultures and be universally treated with antibiotics until culture results return. These guidelines report that the rate of intrapartum fever is about 3%; however, a few large studies suggest that the rate is higher at about 7%. OBJECTIVE: To prospectively evaluate the rate of fever during labor in a large number of deliveries and determine the rate of early onset neonatal sepsis in newborns delivered from mothers with an intrapartum fever compared with the newborns that delivered from mothers that did not have an intrapartum fever...
February 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28215372/the-managing-epilepsy-well-network-advancing-epilepsy-self-management
#20
EDITORIAL
Martha Sajatovic, Barbara C Jobst, Ross Shegog, Yvan A Bamps, Charles E Begley, Robert T Fraser, Erica K Johnson, Dilip K Pandey, Rakale C Quarells, Peter Scal, Tanya M Spruill, Nancy J Thompson, Rosemarie Kobau
Epilepsy, a complex spectrum of disorders, affects about 2.9 million people in the U.S. Similar to other chronic disorders, people with epilepsy face challenges related to management of the disorder, its treatment, co-occurring depression, disability, social disadvantages, and stigma. Two national conferences on public health and epilepsy (1997, 2003) and a 2012 IOM report on the public health dimensions of epilepsy highlighted important knowledge gaps and emphasized the need for evidence-based, scalable epilepsy self-management programs...
March 2017: American Journal of Preventive Medicine
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