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https://www.readbyqxmd.com/read/28212257/matched-case-control-comparative-study-of-laparoscopic-versus-open-pancreaticoduodenectomy-for-malignant-lesions
#1
Yazan S Khaled, Kavi Fatania, Jenifer Barrie, Nicola De Liguori, Rahul Deshpande, Derek A O'Reilly, Basil J Ammori
INTRODUCTION: Advances in surgical technologies allowed safe laparoscopic pancreaticoduodenectomy (LPD). The aim of this study is to compare the oncologic outcomes of LPD to open pancreaticoduodenectomy (OPD) in terms of safety and recurrence rate. MATERIALS AND METHODS: A cohort of 30 patients were matched for age, sex, American Society of Anaesthesiologists, tumor size, pancreatic duct diameter, and histopathologic diagnosis on a 1:1 basis (15 LPD, 15 OPD). Comparison between groups was performed on intention-to-treat basis...
February 16, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28212072/neural-network-based-solutions-for-stochastic-optimal-control-using-path-integrals
#2
Karthikeyan Rajagopal, Sivasubramanya Nadar Balakrishnan, Jerome R Busemeyer
In this paper, an offline approximate dynamic programming approach using neural networks is proposed for solving a class of finite horizon stochastic optimal control problems. There are two approaches available in the literature, one based on stochastic maximum principle (SMP) formalism and the other based on solving the stochastic Hamilton-Jacobi-Bellman (HJB) equation. However, in the presence of noise, the SMP formalism becomes complex and results in having to solve a couple of backward stochastic differential equations...
March 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28211292/clinical-and-functional-outcome-of-open-primary-repair-of-triangular-fibrocartilage-complex-tears-associated-with-distal-radius-fractures
#3
Faisal Johandi, Sreedharan Sechachalam
PURPOSE: We evaluate the clinical and functional outcome of open primary repair of acute TFCC tears in distal radius fracture, when there is gross intraoperative distal radioulnar joint (DRUJ) instability after fixation of the distal radius, in the absence of an ulnar styloid fracture or when the ulnar fracture fragment is too small to be fixed. METHODS: A retrospective review of our institution's distal radius fracture database over a 4-year period (January 2010 to December 2013)...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28211267/efficient-and-selective-uptake-of-tco4-by-a-cationic-metal-organic-framework-material-with-open-ag-sites
#4
Daopeng Sheng, Lin Zhu, Chao Xu, Chengliang Xiao, Yanlong Wang, Yaxing Wang, Lanhua Chen, Juan Diwu, Jing Chen, Zhifang Chai, Thomas E Albrecht-Schmitt, Shuao Wang
99Tc is one of the most problematic radioisotopes in used nuclear fuel owing to its combined features of high fission yield, long half-life, and high environmental mobility. There are only a handful of functional materials that can remove TcO4- anion from aqueous solution and identifying for new, stable materials with high anion-exchange capacities, fast kinetics, and good selectivity remains a challenge. We report here an 8-fold interpenetrated three-dimensional cationic metal-organic framework material, SCU-100, which is assembled from a tetradentate neutral nitrogen-donor ligand and two-coordinate Ag+ cations as potential open metal sites...
February 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28211246/dna-amplification-in-the-field-move-over-pcr-here-comes-lamp
#5
Patricia L M Lee
It would not be an exaggeration to say that among molecular technologies, it is PCR (polymerase chain reaction) that underpins the discipline of molecular ecology as we know it today. With PCR, it has been possible to target the amplification of particular fragments of DNA, which can then be analysed in a multitude of ways. The capability of PCR to amplify DNA from a mere handful of copies further means that conservationists and ecologists are able to sample DNA unobtrusively and with minimal disturbance to the environment and the organisms of interest...
March 2017: Molecular Ecology Resources
https://www.readbyqxmd.com/read/28211206/variable-familial-exudative-vitreoretinopathy-in-a-family-harbouring-variants-in-both-fzd4-and-tspan12
#6
Patrik Schatz, Arif O Khan
PURPOSE: To report a family affected by familial exudative vitreoretinopathy (FEVR) in which more severe disease phenotypes segregated with digenic rather than monogenic variants in FEVR-related genes. METHODS: Phenotype was documented with high-resolution imaging of retinal structure and wide-field fundus photography. Next-generation sequencing (NGS) of known genes involved in FEVR was performed. RESULTS: Three affected individuals within a family with FEVR presented with variable disease severity...
February 16, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28211205/locking-interconversion-of-aromatic-oligoamide-foldamers-by-intramolecular-side-chain-crosslinking-toward-absolute-control-of-helicity-in-synthetic-aromatic-foldamers
#7
Lu Zheng, Chengyuan Yu, Yulin Zhan, Xuebing Deng, Ying Wang, Hua Jiang
A series of foldamers of 8-amino-2-quinolinecarboxylic acid were stapled by intramolecular ring-closing olefin metathesis to generate the constrained aromatic foldamers with varying lengths of hydrocarbon side-chains. Investigations clearly revealed that the side-chain crosslinkers are capable of completely locking the interconversions of the stapled aromatic foldamers over a wide range of temperature in CDCl3, even in C2D2Cl4. Hence, the stapled foldamers with the short hydrocarbon crosslinker can be easily separated by silica gel chromatography to generate foldamers with stable, absolute one-handed helicity...
February 16, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28210793/a-national-population-based-cohort-study-of-urethral-injection-therapy-for-female-stress-and-mixed-urinary-incontinence-the-danish-urogynaecological-database-2007-2011
#8
Margrethe Foss Hansen, Gunnar Lose, Ulrik Schiøler Kesmodel, Kim Oren Gradel
INTRODUCTION AND HYPOTHESIS: Urethral injection therapy (UIT) has been performed since the early 20th century and a variety of agents have been launched. In 2006, polyacrylamide hydrogel (PAGH) was introduced and is now widely used as an agent. The objective was to evaluate the efficacy of PAGH based on a national population over a 5-year period (2007-2011) and the influence of patient-related factors, surgeon experience, and department volume. METHODS: A retrospective cohort study was carried out based on data from the Danish Urogynaecological Database (DugaBase)...
February 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28210564/more-misinformation-on-breast-cancer-screening
#9
COMMENT
Daniel B Kopans
Unfortunately, a great deal of misinformation has accumulated in the breast cancer screening literature that is based on flawed analyses in an effort to reduce access to screening. Quite remarkably, much of this has come from publications in previously highly respected medical journals. In several papers the intervention (mammography screening) is faulted yet the analyses provided no data on who participated in mammography screening, and which cancers were detected by mammography screening. It is remarkable that a highly respected journal can fault an intervention with no data on the intervention...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28210544/cataracts-and-strabismus-associated-with-hand-rearing-using-artificial-milk-formulas-in-bengal-tiger-panthera-tigris-spp-tigris-cubs
#10
Rogério Ribas Lange, Leandro Lima, Erika Frühvald, Vera Sônia Nunes da Silva, Aparecida Sônia de Souza, Fabiano Montiani-Ferreira
The aim of this investigation is to describe the potential contributing nutritional factors involved in the development of ophthalmic and dermatologic changes in four Bengal tiger (Panthera tigris spp tigris) cubs fed an artificial milk formula. The affected animals were compared with two other tiger cubs that had been nursed by their dam naturally. After the first clinical signs appeared, the tiger cubs underwent ophthalmic evaluation. Severe symmetric generalized alopecia over the trunk, sparing the head and distal portion of the front and rear limbs, bilateral cataracts and strabismus were noticed...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28210445/evaluation-of-conventional-protaper-hand-and-protaper-rotary-instrumentation-system-for-apical-extrusion-of-debris-irrigants-and-bacteria-an-in-vitro-randomized-trial
#11
Pinky Kalra, Arathi Rao, Ethel Suman, Ramya Shenoy, Baranya-Shrikrishna Suprabha
BACKGROUND: Endodontic instrumentation carries the risk of over extrusion of debris and bacteria. The technique used and the type of instrumentation influences this risk. AIM: The purpose of this study was to evaluate and compare the K-file, ProTaper hand and ProTaper rotary instrumentation systems for the amount of apically extruded debris, irrigant solution and intracanal bacteria. DESIGN: Experimental single blinded randomized type of in vitro study with sample of 30 single rooted teeth...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210035/effects-of-observation-of-hand-movements-reflected-in-a-mirror-on-cortical-activation-in-patients-with-stroke
#12
Moon-Young Chang, Hwan-Hee Kim, Kyeong-Mi Kim, Jae-Seop Oh, Chel Jang, Tae-Hyung Yoon
[Purpose] The purpose of this study was to examine what changes occur in brain waves when patients with stroke receive mirror therapy intervention. [Subjects and Methods] The subjects of this study were 14 patients with stroke (6 females and 8 males). The subjects were assessed by measuring the alpha and beta waves of the EEG (QEEG-32 system CANS 3000). The mirror therapy intervention was delivered over the course of four weeks (a total of 20 sessions). [Results] Relative alpha power showed statistically significant differences in the F3, F4, O1, and O2 channels in the situation comparison and higher for hand observation than for mirror observation...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28209409/interplay-between-river-dynamics-and-international-borders-the-hirmand-river-between-iran-and-afghanistan
#13
Saleh Yousefi, Saskia Keesstra, Hamid Reza Pourghasemi, Nicola Surian, Somayeh Mirzaee
Fluvial dynamics in riverine borders can play an important role in political relationships between countries. Rivers move and evolve under the influence of natural processes and external drivers (e.g. land use change in river catchments). The Hirmand River is an important riverine border between Iran and Afghanistan. The present study shows the evolution and lateral shifting of the Hirmand River along the international border (25.6km) over a period of 6 decades (1955-2015). Seven data series of aerial photos, topographic maps and Landsat images were used to analyze land cover and channel changes in the study reach...
February 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28208849/finger-length-ratio-2d-4d-in-central-india-and-an-attempt-to-verify-fraternal-birth-order-effect-a-population-based-cross-sectional-study
#14
Arjun Maitra, Chaitali Maitra, Dilip Kumar Jha, Rakesh Biswas
INTRODUCTION: A normal physiology of a human being is not mere a series of functions occurring with specific intensities and timing. There are lot of factors that may change the normal physiological activity within normal limits. Finger length ratio is one of the markers of intrauterine androgen exposure and it is debated and contradicted by many authors. Digit ratio varies among the ethnicities. Many Indian studies show that there is considerable difference in finger length ratio in different population...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208736/time-elastic-generative-model-for-acceleration-time-series-in-human-activity-recognition
#15
Mario Munoz-Organero, Ramona Ruiz-Blazquez
Body-worn sensors in general and accelerometers in particular have been widely used in order to detect human movements and activities. The execution of each type of movement by each particular individual generates sequences of time series of sensed data from which specific movement related patterns can be assessed. Several machine learning algorithms have been used over windowed segments of sensed data in order to detect such patterns in activity recognition based on intermediate features (either hand-crafted or automatically learned from data)...
February 8, 2017: Sensors
https://www.readbyqxmd.com/read/28208503/onset-of-shear-thinning-in-glassy-liquids-shear-induced-small-reduction-of-effective-density
#16
Akira Furukawa
We propose a simple mechanism for describing the onset of shear thinning in a high-density glassy liquid. In a shear flow, along the compression axis, the overlap between neighboring particles is more enhanced than that at equilibrium, meaning that the "effective" size is reduced along this axis. On the other hand, along the extension axis perpendicular to the compression axis, the average structural configurations are stretched, but it does not indicate the expansion of the "effective" size itself. This asymmetric shear flow effect for particles results in a small reduction of the "effective" density...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28208199/systemic-thrombolytic-therapy-for-acute-pulmonary-embolism-who-is-a-candidate
#17
Stavros V Konstantinides, Stefano Barco
Pulmonary embolism (PE) is a major cause of both acute and long-term morbidity for a large number of patients worldwide, and massive PE is frequently fatal. Right ventricular (RV) dysfunction is a key determinant of prognosis in the acute phase of PE. Patients with clinically overt RV failure, that is, with cardiogenic shock or persistent hypotension at presentation (acute high-risk PE), are clearly in need of immediate reperfusion treatment with systemic thrombolysis or, alternatively, surgical or catheter-directed techniques...
February 2017: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28207002/detecting-natural-adaptation-of-the-streptococcus-thermophilus-crispr-cas-systems-in-research-and-classroom-settings
#18
Alexander P Hynes, Marie-Laurence Lemay, Luc Trudel, Hélène Deveau, Michel Frenette, Denise M Tremblay, Sylvain Moineau
CRISPR (clustered regularly interspaced short palindromic repeats)-Cas systems have been adapted into a powerful genome-editing tool. The basis for the flexibility of the tool lies in the adaptive nature of CRISPR-Cas as a bacterial immune system. Here, we describe a protocol to experimentally demonstrate the adaptive nature of this bacterial immune system by challenging the model organism for the study of CRISPR adaptation, Streptococcus thermophilus, with phages in order to detect natural CRISPR immunization...
March 2017: Nature Protocols
https://www.readbyqxmd.com/read/28206672/assessment-of-a-novel-point-of-care-ultrasound-curriculum-s-effect-on-competency-measures-in-family-medicine-graduate-medical-education
#19
Paul Bornemann
OBJECTIVES: Point-of-care ultrasound has been shown to decrease the use of expensive diagnostic studies and improve quality outcome measures. Currently, there is a large desire for training in family medicine residencies, but very few programs have established curricula. We sought to develop a family medicine residency curriculum and evaluate it with tools we developed. We wanted our curriculum to be easy to adopt by other residency programs, even if they did not have many well-trained ultrasound faculty...
February 16, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28205480/extensor-tendon-instability-due-to-sagittal-band-injury-in-a-martial-arts-athlete-a-case-report
#20
Andrew Kochevar, Ghazi Rayan
A Taekwondo participant sustained a hand injury from punching an opponent that resulted in painful instability of the ring finger extensor digitorum communis tendon due to sagittal band damage. His symptoms resolved after reconstructive surgery on the sagittal band (SB) with stabilization of the extensor tendon over the metacarpophalangeal joint.
March 2017: Journal of Hand Surgery Asian-Pacific Volume
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