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https://www.readbyqxmd.com/read/28741979/systematic-review-of-the-literature-on-triclosan-and-health-outcomes-in-humans
#1
Michael Goodman, Daniel Q Naiman, Judy S LaKind
The ability of epidemiologic evidence to inform regulatory decisions is largely dependent on the coherence and quality of the published literature. This systematic review examines the quality and consistency of studies assessing health outcomes associated with exposure to triclosan (TCS), an antimicrobial chemical with a short physiologic half-life. We used elements of the Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals instrument to evaluate aspects of study quality. Each methodological domain - overall design, exposure assessment, and data analysis - was categorized according to three tiers where Tier 1 indicated the highest quality...
July 25, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28741413/modulating-children-s-manual-preference-through-spontaneous-nondominant-hand-use
#2
Juliana Maia Garcia, Luis Augusto Teixeira
We evaluated the effect of repeated use of the nonpreferred hand on young children's manual preference by positioning toys in the left hemifield in egocentric coordinates to induce right-handed 4- to 5-year-olds to use their left hands spontaneously. We induced motor activities in the laterally biased workspace by presenting tasks in a ludic context over different days, similar to their daily kindergarten experience. Preceding and following these lateralized experiences, the children were tested on a task requiring reaching, grasping, and inserting cards into a slot...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/28740941/effects-of-whole-body-vibration-intervention-on-handgrip-strength-of-brazilian-healthy-soldiers
#3
Danielle Soares Morel, Eloá Moreira-Marconi, Samuel Brandão Sobrinho Neto, Laisa Liane Paineiras Domingos, Patrícia Lopes de Souza, Danúbia da Cunha de Sá Caputo, Glenda Dias Costa, Cláudia Ferreira de Figueiredo, Roberto Carlos Resende Carmo, Patrícia de Castro de Paiva, Cintia Renata Sousa Gonçalves, Cristiane Ribeiro Kütter, Eliane de Oliveira Guedes de Aguiar, Mario Bernardo-Filho
BACKGROUND: Whole body vibration (WBV) exercises have been investigated as an alternative and complementary method to traditional resistance programs for fitness improvements in healthy subjects. Active militaries must have a high fitness level and have to improve some physical abilities to accomplish some specific tasks in Army, as climb ropes, climb walls and pull up. MATERIALS AND METHODS: Seven young and healthy soldiers from Brazilian Army were exposed to mechanical vibration in a push-up position, with different frequencies, as 25 (first session), 30 (second session), 35 (third session), 40 (fourth session) and 45 Hz (fifth session)...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28738276/the-impact-of-accelerated-high-frequency-rtms-on-brain-neurochemicals-in-treatment-resistant-depression-insights-from-1-h-mr-spectroscopy
#4
Chris Baeken, Jean-Pascal Lefaucheur, Peter Van Schuerbeek
OBJECTIVE: Although accelerated repetitive transcranial magnetic stimulation (rTMS) designs seem to be able to alleviate mood over a relatively short period of time, no studies yet examined the cellular effects on neurochemicals with regard to working mechanisms, safety and neural integrity. METHODS: Eighteen right-handed antidepressant-free unipolar treatment resistant depressed (TRD) patients participated in this sham-controlled accelerated high frequency (aHF)-rTMS (1)H MR spectroscopy study applied to the left dorsolateral prefrontal cortex (DLPFC)...
July 6, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28737902/absorption-of-low-energy-uv-radiation-by-human-telomere-g-quadruplexes-generates-long-lived-guanine-radical-cations
#5
Akos Banyasz, Lara Martínez-Fernández, Clémence Balty, Marion Perron, Thierry Douki, Roberto Improta, Dimitra Markovitsi
Telomeres, which are involved in cell division, carcinogenesis, and aging and constitute important therapeutic targets, are prone to oxidative damage. This propensity has been correlated with the presence of guanine-rich sequences, capable of forming four-stranded DNA structures (G-quadruplexes). Here, we present the first study on oxidative damage of human telomere G-quadruplexes without mediation of external molecules. Our investigation has been performed for G-quadruplexes formed by folding of GGG(TTAGGG)3 single strands in buffered solutions containing Na(+) cations (TEL21/Na(+))...
July 24, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28737285/role-of-endoscopic-ultrasound-guided-fine-needle-aspiration-biopsy-in-the-diagnosis-of-lymphoma-of-the-pancreas-a-clinicopathological-study-of-nine-cases
#6
S Sadaf, A Loya, N Akhtar, M A Yusuf
OBJECTIVE: Endoscopic ultrasound-guided-fine needle aspiration (EUS-FNA) is an established first-line procedure in the management of solid and cystic pancreatic masses. Lymphoma is an uncommon diagnosis in EUS-FNA of the pancreas, and it is more common for such a diagnosis to be because of secondary involvement of the pancreas by a lymphoproliferative disorder than for this to represent isolated primary pancreatic lymphoma (PPL). We present the clinical, EUS and cytological features of these lesions...
July 24, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28736689/induced-pluripotent-stem-cells-global-research-trends
#7
REVIEW
Takaharu Negoro, Hanayuki Okura, Akifumi Matsuyama
The induced pluripotent stem cell (iPSC) was first described more than 10 years ago and is currently used in various basic science and clinical research fields. The aim of this report is to examine the trends in research using iPSCs over the last 10 years. The 2006-2016 PubMed database was searched using the MeSH term "induced pluripotent stem cells." Only original research articles were selected, with a total of 3323 articles. These were classified according to research theme into reprogramming, differentiation protocols for specific cells and/or tissues, pathophysiological research on diseases, and discovery of new drugs, and then the trends over the years were analyzed...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28736668/in-vivo-photoacoustics-and-high-frequency-ultrasound-imaging-of-mechanical-high-intensity-focused-ultrasound-hifu-ablation
#8
Khalid Daoudi, Martijn Hoogenboom, Martijn den Brok, Dylan Eikelenboom, Gosse J Adema, Jürgen J Fütterer, Chris L de Korte
The thermal effect of high intensity focused ultrasound (HIFU) has been clinically exploited over a decade, while the mechanical HIFU is still largely confined to laboratory investigations. This is in part due to the lack of adequate imaging techniques to better understand the in-vivo pathological and immunological effects caused by the mechanical treatment. In this work, we explore the use of high frequency ultrasound (US) and photoacoustics (PA) as a potential tool to evaluate the effect of mechanical ablation in-vivo, e...
April 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28736508/3-dof-force-sensing-motorized-micro-forceps-for-robot-assisted-vitreoretinal-surgery
#9
Berk Gonenc, Alireza Chamani, James Handa, Peter Gehlbach, Russell H Taylor, Iulian Iordachita
In vitreoretinal surgery, membrane peeling is a prototypical task where a layer of fibrous tissue is delaminated off the retina with a micro-forceps by applying very fine forces that are mostly imperceptible to the surgeon. Previously we developed sensitized ophthalmic surgery tools based on fiber Bragg grating (FBG) strain sensors, which were shown to precisely detect forces at the instrument's tip in two degrees of freedom perpendicular to the tool axis. This paper presents a new design that employs an additional sensor to capture also the tensile force along the tool axis...
June 1, 2017: IEEE Sensors Journal
https://www.readbyqxmd.com/read/28736088/fetopathological-examination-for-the-fetuses-with-down-syndrome-in-tunisia-epidemiological-study-and-associated-malformations
#10
Meriem Aloui, Kaouther Nasri, Nadia Ben Jemaa, Meriem Sahraoui, Aida Masmoudi, Dorra Zghal, Dalenda Chelli, Habiba Chaâbouni, Abdel Majid Ben Hamida, Soumeya Siala Gaigi, Raja Marrakchi
BACKGROUND: For Down syndrome (DS), traditional epidemiological studies to determine the prevalence, cause, and clinical significance of the syndrome have been conducted over the last 100 years. In Tunisia, the current work is the first in-depth study in epidemiology of DS from fetopathological data. AIM OF THE STUDY: The aim of this epidemiological study was to determine the impact of some feto-maternal characteristics in occurrence of DS and to search the frequency of associated congenital malformations with this syndrome...
May 8, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28735756/incidence-and-determinants-of-hyperkalemia-and-hypokalemia-in-a-large-healthcare-system
#11
Erik Nilsson, Alessandro Gasparini, Johan Ärnlöv, Hairong Xu, Karin M Henriksson, Josef Coresh, Morgan E Grams, Juan Jesus Carrero
BACKGROUND: Hypo- and hyperkalemia in clinical settings are insufficiently characterized and large-scale data from Europe lacking. We studied incidence and determinants of these abnormalities in a large Swedish healthcare system. METHODS: Observational study from the Stockholm CREAtinine Measurements project, including adult individuals from Stockholm accessing healthcare in 2009 (n=364,955). Over 3-years, we estimated the incidence of hypokalemia, defined as potassium<3...
July 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28735225/no-consistent-cooling-of-the-real-hand-in-the-rubber-hand-illusion
#12
Alyanne M de Haan, Haike E Van Stralen, Miranda Smit, Anouk Keizer, Stefan Van der Stigchel, H Chris Dijkerman
In the rubber hand illusion (RHI), participants view a rubber hand that is stroked synchronously with their real, hidden hand. This procedure results in experiencing an increased sense of ownership over the rubber hand and demonstrates how multisensory information (vision, touch) can influence the sense of body ownership. However, it has also been suggested that a (lack of) sense of ownership over an own body part may in turn influence bodily processes. This suggestion has previously been supported by the observation that a decrease in skin temperature in the real hand correlated with ownership over the rubber hand...
July 20, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28735203/grape-stalk-application-for-caffeine-removal-through-adsorption
#13
Rodrigo Portinho, Odivan Zanella, Liliana Amaral Féris
Concern over emerging pollutants presence in water resources is growing, justifying the search for alternative or additional techniques to those applied in conventional water treatment processes. Use of adsorption with agricultural wastes directly as adsorbents or as precursors for activated carbon synthesis is a viable method, combining removal efficiency, low cost and biodegradability of the material applied. This study investigated the employability of grape stalk, a waste from grape industrialization process without effective use, in caffeine removal from aqueous solution...
July 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28734718/shoulder-activity-level-and-progression-of-degenerative-cuff-disease
#14
Jay D Keener, Nathan W Skelley, Georgia Stobbs-Cucchi, Karen Steger-May, Aaron M Chamberlain, Alex W Aleem, Robert H Brophy
BACKGROUND: This study prospectively examined the relationship of direct and indirect measures of shoulder activity with the risks of tear progression and pain development in subjects with an asymptomatic degenerative rotator cuff tear. METHODS: A cohort of asymptomatic degenerative rotator cuff tears was prospectively monitored annually, documenting tear size progression with ultrasound imaging and potential shoulder pain development. Shoulder activity level, self-reported occupational and physical demand level, and hand dominance were compared with risks of tear enlargement and future pain development...
July 19, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28732553/diversity-application-and-synthetic-biology-of-industrially-important-aspergillus-fungi
#15
Hee-Soo Park, Sang-Cheol Jun, Kap-Hoon Han, Seung-Beom Hong, Jae-Hyuk Yu
The filamentous fungal genus Aspergillus consists of over 340 officially recognized species. A handful of these Aspergillus fungi are predominantly used for food fermentation and large-scale production of enzymes, organic acids, and bioactive compounds. These industrially important Aspergilli primarily belong to the two major Aspergillus sections, Nigri and Flavi. Aspergillus oryzae (section Flavi) is the most commonly used mold for the fermentation of soybeans, rice, grains, and potatoes. Aspergillus niger (section Nigri) is used in the industrial production of various enzymes and organic acids, including 99% (1...
2017: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/28732453/real-world-chart-review-study-of-adverse-events-management-in-patients-taking-tyrosine-kinase-inhibitors-to-treat-metastatic-renal-cell-carcinoma
#16
Sandy Srinivas, Dara Stein, Dana Y Teltsch, Sunning Tao, Laura Cisar, Krishnan Ramaswamy
Purpose The purpose is to describe management of adverse events of special interest across tyrosine kinase inhibitors approved for metastatic renal cell carcinoma. Methods We conducted a retrospective chart review in metastatic renal cell carcinoma patients initiating tyrosine kinase inhibitor monotherapy between 15 November 2010 and 15 November 2013, and experiencing ≥ 1 adverse events of special interest (diarrhea, fatigue, hand-foot syndrome, hypertension, or stomatitis/mucositis) within 3 months of initiation...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28732316/a-user-friendly-technical-set-up-for-infrared-photography-of-forensic-findings
#17
Thomas Rost, Nicole Kalberer, Eva Scheurer
Infrared photography is interesting for a use in forensic science and forensic medicine since it reveals findings that normally are almost invisible to the human eye. Originally, infrared photography has been made possible by the placement of an infrared light transmission filter screwed in front of the camera objective lens. However, this set-up is associated with many drawbacks such as the loss of the autofocus function, the need of an external infrared source, and long exposure times which make the use of a tripod necessary...
July 10, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28732208/longitudinal-investigation-of-the-parietal-lobe-anatomy-in-bipolar-disorder-and-its-association-with-general-functioning
#18
Adele Ferro, Carolina Bonivento, Giuseppe Delvecchio, Marcella Bellani, Cinzia Perlini, Nicola Dusi, Veronica Marinelli, Mirella Ruggeri, A Carlo Altamura, Benedicto Crespo-Facorro, Paolo Brambilla
The parietal lobe (PL) supports cognitive domains, including attention and memory, which are impaired in bipolar disorder (BD). Although cross-sectional voxel-based morphometry studies found reduced PL grey matter (GM) in BD, none has longitudinally focused on PL anatomy in BD, relating it to patients' functioning. Thirty-eight right-handed BD patients and 42 matched healthy subjects (HS) underwent a Magnetic Resonance Imaging (MRI) scan at baseline. Seventeen BD patients and 16 matched HS underwent a follow-up MRI...
June 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28730744/improving-hospital-discharge-arrangements-for-people-who-are-homeless-a-realist-synthesis-of-the-intermediate-care-literature
#19
REVIEW
Michelle Cornes, Martin Whiteford, Jill Manthorpe, Joanne Neale, Richard Byng, Nigel Hewett, Michael Clark, Alan Kilmister, James Fuller, Robert Aldridge, Michela Tinelli
This review presents a realist synthesis of "what works and why" in intermediate care for people who are homeless. The overall aim was to update an earlier synthesis of intermediate care by capturing new evidence from a recent UK government funding initiative (the "Homeless Hospital Discharge Fund"). The initiative made resources available to the charitable sector to enable partnership working with the National Health Service (NHS) in order to improve hospital discharge arrangements for people who are homeless...
July 20, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28730687/efficacy-of-abatacept-in-patients-with-rheumatoid-arthritis-as-assessed-by-magnetic-resonance-imaging-of-bilateral-hands
#20
Yuji Kukida, Akiko Kasahara, Takahiro Seno, Takuya Inoue, Risa Sagawa, Takashi Kida, Amane Nakabayashi, Hidetake Nagahara, Ken Murakami, Toshifumi Sugitani, Satoshi Morita, Hirotoshi Ito, Ryo Oda, Hiroyoshi Fujiwara, Masataka Kohno, Yutaka Kawahito
AIM: To examine the efficacy of abatacept in patients with rheumatoid arthritis (RA) using magnetic resonance imaging (MRI) of bilateral hands. METHOD: This prospective study included 35 RA patients. MRI of bilateral hands was performed at baseline and after 12 months of treatment with intravenous abatacept. MRI images were scored for synovitis, osteitis, erosion and joint space narrowing (JSN) according to the RA MRI Scoring System (RAMRIS). The primary endpoint was the change in RAMRIS score from baseline...
July 21, 2017: International Journal of Rheumatic Diseases
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