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https://www.readbyqxmd.com/read/28342992/estimating-removals-of-contaminants-of-emerging-concern-from-wastewater-treatment-plants-the-critical-role-of-wastewater-hydrodynamics
#1
Zeina Baalbaki, Tamanna Sultana, Chris Metcalfe, Viviane Yargeau
Accurate data is needed to evaluate the capacity of wastewater treatments plants (WWTPs) to remove contaminants of emerging concern (CECs). The variability of CEC removals reported in the literature has raised questions about the methods used to estimate removals. In this study, we used the recently proposed "fractionated approach" to account for the influence of hydrodynamics in WWTPs and applied this method for estimating the removal of 23 target CECs. Data on the conductivity and temperature of wastewater at two WWTPs were used to determine the hydraulic model that best described the flow regime of treatment units...
March 19, 2017: Chemosphere
https://www.readbyqxmd.com/read/28342677/prevalence-of-voice-disorders-in-singers-systematic-review-and-meta-analysis
#2
Pedro Melo Pestana, Susana Vaz-Freitas, Maria Conceição Manso
OBJECTIVE: The study aimed to review the prevalence of self-reported voice disorders in singers. STUDY DESIGN: The study is a systematic review and meta-analysis. METHODS: A systematic review of five major scientific databases was conducted. An extensive search strategy was used considering the rules of each database. Original articles were included only if they had data related to self-perception of dysphonia in the past. Furthermore, heterogeneity and its relative significance were assessed...
March 22, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28340430/bilateral-sequential-motor-cortex-stimulation-and-skilled-task-performance-with-non-dominant-hand
#3
Milan B Jelić, Saša R Filipović, Sladjan D Milanović, Vuk B Stevanović, Ljubica Konstantinović
OBJECTIVE: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. METHODS: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation...
March 6, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28339997/straight-run-vs-sex-separate-rearing-for-2-broiler-genetic-lines-part-1-live-production-parameters-carcass-yield-and-feeding-behavior
#4
M J Da Costa, S Zaragoza-Santacruz, T J Frost, J Halley, G M Pesti
The objective of this experiment was to evaluate the effects of raising broilers under sex separate and straight-run conditions for 2 broiler strains. Day-old Ross 308 and Ross 708 chicks (n = 1,344) were separated by sex and placed in 48 pens according to the rearing type: sex separate (28 males or 28 females) or straight-run (14 males + 14 females). There were 3 dietary phases: starter (zero to 17 d), grower (17 to 32 d), and finisher (32 to 48 d). Birds' individual BW and feed intakes were measured at 12, 17, 25, 32, 42, and 48 d to evaluate performance...
March 4, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339636/a-before-after-study-of-multidisciplinary-out-of-hours-handover-combining-management-and-frontline-efforts-to-create-sustainable-improvement
#5
Christopher Pennell, Lorna Flynn, Belinda Boulton, Tracey Hughes, Graham Walker, Peter McCulloch
Objective: The importance of implementation strategy in systems improvement is increasingly recognized and both 'bottom-up' and 'top-down' approaches have significant barriers. A trial of a combined approach involving frontline and managerial staff therefore seems merited. We attempted to improve handover using a Human Factors-based approach integrated with a combined 'top and bottom' implementation strategy. Design: A before-after study was conducted across 9 months...
February 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28339311/lung-rads-category-4x-does-it-improve-prediction-of-malignancy-in-subsolid-nodules
#6
Kaman Chung, Colin Jacobs, Ernst T Scholten, Jin Mo Goo, Helmut Prosch, Nicola Sverzellati, Francesco Ciompi, Onno M Mets, Paul K Gerke, Mathias Prokop, Bram van Ginneken, Cornelia M Schaefer-Prokop
Purpose To evaluate the added value of Lung CT Screening Reporting and Data System (Lung-RADS) assessment category 4X over categories 3, 4A, and 4B for differentiating between benign and malignant subsolid nodules (SSNs). Materials and Methods SSNs on all baseline computed tomographic (CT) scans from the National Lung Cancer Trial that would have been classified as Lung-RADS category 3 or higher were identified, resulting in 374 SSNs for analysis. An experienced screening radiologist volumetrically segmented all solid cores and located all malignant SSNs visible on baseline scans...
March 24, 2017: Radiology
https://www.readbyqxmd.com/read/28339133/prospective-comparison-of-diagnostic-accuracy-between-point-of-care-and-conventional-ultrasound-in-a-general-diagnostic-department-implications-for-resource-limited-settings
#7
Steffen J A Haider, Roberta diFlorio-Alexander, David H Lam, Joo Y Cho, Jae Ho Sohn, Robert Harris
OBJECTIVES: To compare the diagnostic accuracy of hand-held point of care (POC) versus conventional sonography in a general diagnostic setting with the intention to inform medical providers or clinicians on the rational use of POC ultrasound in resource limited settings. METHODS: Over 3 months in 2010, 47 patients were prospectively enrolled at a single academic center to obtain 54 clinical conventional ultrasound examinations and 54 study-only POC ultrasound examinations...
March 24, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28338585/a-16-year-journey-in-the-study-of-rheumatoid-hand-disease
#8
Kevin C Chung, Sandra V Kotsis
Evidence-based medicine is a relatively new concept in hand surgery. A lack of high-level evidence often leads to uncertainty in the effectiveness of various procedures and regional variation in their use. Rheumatoid hand surgery has been plagued by a lack of quality data that has caused controversy between rheumatologists and hand surgeons. Research over the past 16 years has strived to provide data that can be used to provide evidence-based care for rheumatoid arthritis (RA) patients. The Silicone Arthroplasty in Rheumatoid Arthritis (SARA) Study is a prospective, long-term cohort study of RA patients with severe metacarpophalangeal joint deformity who have elected to undergo or to not undergo metacarpophalangeal joint arthroplasty...
March 3, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28338392/the-effects-of-low-intensity-therapeutic-ultrasound-litus-on-measurable-outcomes-a-critically-appraised-topic
#9
Sarah Daniels, Gabriela Santiago, Jennifer Cuchna, Bonnie Van Lunen
Therapeutic Ultrasound (US) is a popular modality among healthcare professionals and is used to treat a variety of musculoskeletal conditions.(1) Throughout the past 70 years of clinical use,(2) ultrasound has been shown to be an effective way to decrease pain,(2,3) increase tissue temperature,(4) and decrease tissue stiffness of trigger points,(5) amidst other benefits. Treatment parameters with US are typically high-intensity and occur over a short period of time (minutes). The US machine is large and stationary, forcing patients to be non-mobile for the duration of their treatment...
March 24, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28338139/adsorption-of-small-inorganic-molecules-on-a-defective-mos2-monolayer
#10
César González, Blanca Biel, Yannick J Dappe
We present a theoretical study of molecular adsorption on defects on a MoS2 monolayer. Based on Density Functional Theory, our calculations confirm that small inorganic molecules, such as CO2, CO, H2O, NO, NO2, H2 and N2, remain bonded to the pristine monolayer through weak van der Waals interactions, suggesting that the molecules may easily diffuse over the clean monolayer. On the other hand, the introduction of defects can lead to three different situations, depending on the defect and the molecule considered: physisorption, chemical (strong) bonding to the metallic defects, namely the Mo substitutional atoms on the S vacancies, and dissociation, that can take place spontaneously at 0 K in some specific cases or by the effect of thermal agitation in molecules such as CO2 or NO2 on the S vacancy...
March 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28337673/progression-free-survival-as-a-surrogate-for-overall-survival-in-clinical-trials-of-targeted-therapy-in-advanced-solid-tumors
#11
Stefan Michiels, Everardo D Saad, Marc Buyse
Over the past 15 years, targeted therapy has revolutionized the systemic treatment of cancer. In parallel, there has been a growing debate on the choice of end points in clinical trials in oncology. This debate basically hinges on the choice between overall survival (OS) and progression-free survival (PFS). PFS is advantageous because it is measured earlier than OS, requires a smaller sample size than OS to achieve the desired power, and is not influenced by cross-over. On the other hand, PFS is prone to measurement error and bias, and may not capture the entire treatment effect on the outcomes of most interest to patients with an incurable disease: a prolonged survival and improved quality of life...
March 23, 2017: Drugs
https://www.readbyqxmd.com/read/28337543/superiority-of-stapled-side-to-side-gastrojejunostomy-over-conventional-hand-sewn-end-to-side-gastrojejunostomy-for-reducing-the-risk-of-primary-delayed-gastric-emptying-after-subtotal-stomach-preserving-pancreaticoduodenectomy
#12
Yasuhiro Murata, Akihiro Tanemura, Hiroyuki Kato, Naohisa Kuriyama, Yoshinori Azumi, Masashi Kishiwada, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Shuji Isaji
BACKGROUND AND PURPOSE: Delayed gastric emptying (DGE) is the most common complication following pancreaticoduodenectomy (PD). The clinical efficacy of stapled side-to-side anastomosis using a laparoscopic stapling device during alimentary reconstruction in PD is not well understood and its superiority over conventional hand-sewn end-to-side anastomosis remains controversial. The objective of this study was to evaluate the effectiveness of the stapled side-to-side anastomosis in preventing the development of DGE after PD...
March 23, 2017: Surgery Today
https://www.readbyqxmd.com/read/28336835/improving-powder-magnetic-core-properties-via-application-of-thin-insulating-silica-nanosheet-layers-on-iron-powder-particles
#13
Toshitaka Ishizaki, Hideyuki Nakano, Shin Tajima, Naoko Takahashi
A thin, insulating layer with high electrical resistivity is vital to achieving high performance of powder magnetic cores. Using layer-by-layer deposition of silica nanosheets or colloidal silica over insulating layers composed of strontium phosphate and boron oxide, we succeeded in fabricating insulating layers with high electrical resistivity on iron powder particles, which were subsequently used to prepare toroidal cores. The compact density of these cores decreased after coating with colloidal silica due to the substantial increase in the volume, causing the magnetic flux density to deteriorate...
December 23, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28336096/multigenerational-effects-of-two-glucocorticoids-prednisolone-and-dexamethasone-on-life-history-parameters-of-crustacean-ceriodaphnia-dubia-cladocera
#14
Navdeep Bal, Anupama Kumar, Jun Du, Dayanthi Nugegoda
Synthetic glucocorticoids (GCs) such as dexamethasone (DEX) and prednisolone (PDS) have been used since the 1940s to cure inflammatory and auto-immune disorders. Their use has been linked to a host of deleterious effects in aquatic ecosystems such as osteoporosis in vertebrates, developmental impairments in molluscs and reduced fecundity and growth in cladocerans. Apart from these handful of studies, the effects of GCs on aquatic biota are largely unknown. The present study is a first of its kind aiming to assess the multi-generational exposure effects of DEX and PDS on the life history parameters of Ceriodaphnia dubia (C...
March 20, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28335810/structured-relearning-of-activities-of-daily-living-in-dementia-the-randomized-controlled-redali-dem-trial-on-errorless-learning
#15
Sebastian Voigt-Radloff, Maartje M E de Werd, Rainer Leonhart, Danielle H E Boelen, Marcel G M Olde Rikkert, Klaus Fliessbach, Stefan Klöppel, Bernhard Heimbach, Andreas Fellgiebel, Richard Dodel, Gerhard W Eschweiler, Lucrezia Hausner, Roy P C Kessels, Michael Hüll
BACKGROUND: Errorless learning (EL) is a method for optimizing learning, which uses feed-forward instructions in order to prevent people from making mistakes during the learning process. The majority of previous studies on EL taught patients with dementia artificial tasks of little or no relevance for their daily lives. Furthermore, only a few controlled studies on EL have so far been performed and just a handful of studies have examined the long-term effects of EL. Tasks were not always trained in the patients' natural or home environment, limiting the external validity of these studies...
March 23, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28334999/rewiring-the-primary-somatosensory-cortex-in-carpal-tunnel-syndrome-with-acupuncture
#16
Yumi Maeda, Hyungjun Kim, Norman Kettner, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Rebecca Ong-Sutherland, Pia Mezzacappa, Alexandra Libby, Ishtiaq Mawla, Leslie R Morse, Ted J Kaptchuk, Joseph Audette, Vitaly Napadow
Carpal tunnel syndrome is the most common entrapment neuropathy, affecting the median nerve at the wrist. Acupuncture is a minimally-invasive and conservative therapeutic option, and while rooted in a complex practice ritual, acupuncture overlaps significantly with many conventional peripherally-focused neuromodulatory therapies. However, the neurophysiological mechanisms by which acupuncture impacts accepted subjective/psychological and objective/physiological outcomes are not well understood. Eligible patients (n = 80, 65 female, age: 49...
March 2, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28334802/engagement-strategies-that-foster-community-self-determination-in-participatory-research-insider-ownership-through-outsider-championship
#17
Jon Salsberg, Soultana Macridis, Enrique Garcia Bengoechea, Ann C Macaulay, Spencer Moore
Background.: In order to maximize the benefits of community-based participatory research, effective ownership over the research process must be at least equally in the hands of the community. A previous social network analysis documented that the participatory research process shifted ownership from academic to community partners, but did not show what actions and strategies fostered this shift. Objectives.: This study follows the trajectory of a community-academic partnership and asks, from the perspective of the project stakeholders, which actions and strategies over the lifespan of the research led to the observed shift in ownership and decision-making from the original external academics to the community stakeholders? Methods...
February 18, 2017: Family Practice
https://www.readbyqxmd.com/read/28334676/manual-motor-speed-dysfunction-as-a-neurocognitive-endophenotype-in-euthymic-bipolar-disorder-patients-and-their-healthy-relatives-evidence-from-a-5-year-follow-up-study
#18
P Correa-Ghisays, V Balanzá-Martínez, G Selva-Vera, J Vila-Francés, E Soria-Olivas, J Vivas-Lalinde, C San Martín, A M Borrás, R Ayesa-Arriola, J Sanchez-Moreno, J Sánchez-Ort, B Crespo-Facorro, E Vieta, R Tabarés-Seisdedos
BACKGROUND: Few studies have examined Manual Motor Speed (MMS) in bipolar disorder (BD). The aim of this longitudinal, family study was to explore whether dysfunctional MMS represents a neurocognitive endophenotype of BD. METHODS: A sample of 291 subjects, including 131 BD patients, 77 healthy first-degree relatives (BD-Rel), and 83 genetically-unrelated healthy controls (HC), was assessed with the Finger-Tapping Test (FTT) on three occasions over a 5-year period...
March 16, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28334043/cc-223-blocks-mtorc1-c2-activation-and-inhibits-human-hepatocellular-carcinoma-cells-in-vitro-and-in-vivo
#19
Zichen Xie, Jiqin Wang, Mei Liu, Deshan Chen, Chao Qiu, Keyu Sun
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related human mortalities. Over-activation of mammalian target of rapamycin (mTOR) is important for HCC tumorigenesis and progression. The current study assessed the potential anti-HCC activity by a novel mTOR kinase inhibitor, CC-223. We demonstrate that CC-223, at nM concentrations, induced profound cytotoxic and anti-proliferative activities against established HCC cell lines (HepG2, KYN-2 and Huh-7) and primary human HCC cells. Meanwhile, CC-223 activated caspase-3/-9 and apoptosis in the above HCC cells...
2017: PloS One
https://www.readbyqxmd.com/read/28333585/fast-estimation-of-approximate-matrix-ranks-using-spectral-densities
#20
Shashanka Ubaru, Yousef Saad, Abd-Krim Seghouane
Many machine learning and data-related applications require the knowledge of approximate ranks of large data matrices at hand. This letter presents two computationally inexpensive techniques to estimate the approximate ranks of such matrices. These techniques exploit approximate spectral densities, popular in physics, which are probability density distributions that measure the likelihood of finding eigenvalues of the matrix at a given point on the real line. Integrating the spectral density over an interval gives the eigenvalue count of the matrix in that interval...
March 23, 2017: Neural Computation
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