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https://www.readbyqxmd.com/read/28227698/predicting-brain-stimulation-treatment-outcomes-of-depressed-patients-through-the-classification-of-eeg-oscillations
#1
Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Michael Breakspear, Ahmed Al-Ani, Tjeerd W Boonstra, Colleen K Loo
Major depressive disorder (MDD) is a mental disorder that is characterized by negative thoughts, mood and behavior. Transcranial direct current stimulation (tDCS) has recently emerged as a promising brain-stimulation treatment for MDD. A standard tDCS treatment involves numerous sessions that run over a few weeks, however, not all participants respond to this type of treatment. This study aims to predict which patients improve in mood and cognition in response to tDCS treatment by analyzing electroencephalography (EEG) of MDD patients that was collected at the start of tDCS treatment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227597/long-term-vital-sign-measurement-using-a-non-contact-vital-sign-sensor-inside-an-office-cubicle-setting
#2
T Hall, N A Malone, J Tsay, J Lopez, T Nguyen, R E Banister, D Y C Lie, T Hall, N A Malone, J Tsay, J Lopez, T Nguyen, R E Banister, D Y C Lie, T Hall, J Lopez, N A Malone, T Nguyen, J Tsay, D Y C Lie, R E Banister
Heart and respiration rates can be wirelessly measured by extracting the phase shift caused by the periodic displacement of a patient's chest wall. We have developed a phased-array Doppler-based non-contact vital sign (NCVS) sensor capable of long-term vital signs monitoring using an automatic patient tracking and movement detection algorithm. Our NCVS sensor achieves non-contact heart rate monitoring with accuracies of over 90% (i.e, within ±5 Beats-Per-Minute vs. a reference sensor) across a large number of data points collected over various days of the week inside a typical office cubicle setting at a distance of 1...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227476/a-smartphone-based-system-for-assessing-intraocular-pressure
#3
A Mariakakis, E Wang, S Patel, J C Wen, A Mariakakis, E Wang, S Patel, J C Wen, E Wang, A Mariakakis, S Patel, J C Wen
The measurement of intraocular pressure (IOP) is an important vital sign for the eye, particularly for the diagnosis of glaucoma. Procedures for measuring IOP have been used by eye care professionals for over 100 years, but those without access to such professionals often go undiagnosed. We present a smartphone-based system that can be operated by minimally trained users to measure IOP. The system emulates fixed-force tonometry using a low-cost mechanical attachment to the smartphone. Video is captured through the attachment and then processed in real-time to provide an absolute estimate of the patient's intraocular pressure...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227215/telehomecare-telecommunication-framework-from-remote-patient-monitoring-to-video-visits-and-robot-telepresence
#4
Pierre Lepage, Dominic Letourneau, Mathieu Hamel, Simon Briere, Helene Corriveau, Michel Tousignant, Francois Michaud, Pierre Lepage, Dominic Letourneau, Mathieu Hamel, Simon Briere, Helene Corriveau, Michel Tousignant, Francois Michaud, Simon Briere, Dominic Letourneau, Helene Corriveau, Michel Tousignant, Francois Michaud, Mathieu Hamel, Pierre Lepage
Over the last few years, the number of remote patient monitoring (RPM) products and of videoconferencing systems has exploded. There is also a significant number of research initiatives addressing the use of service robots for assistance in daily living activities. From a technological standpoint, providing telehomecare services is certainly feasible. However, one technological barrier is to have access to a telecommunication platform that can be adapted to address the broad range of specifications and requirements of clinical and telehealth applications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226570/a-wearable-signal-acquisition-system-for-physiological-signs-including-throat-ppg
#5
Yizhou Zhong, Yun Pan, Ling Zhang, Kwang-Ting Cheng, Yizhou Zhong, Yun Pan, Ling Zhang, Kwang-Ting Cheng, Yizhou Zhong, Ling Zhang, Kwang-Ting Cheng, Yun Pan
This paper presents a wearable signal acquisition system, which can measure physiological signs, i.e., electrocardiogram (ECG) and photoplethysmogram (PPG). The system is comprised of two parts: (1) an ECG sensor implemented in the master board which will be mounted on the chest and, (2) a combined PPG and motion sensor implemented in the slave board which will be worn around the neck area. The single-lead ECG, the single-channel PPG, and the 3-channel accelerometer signals are all sampled at 200Hz, and transmitted to an Android app through Bluetooth® low energy (BLE) in real time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225783/heart-and-skeletal-muscle-inflammation-hsmi-disease-diagnosed-on-a-british-columbia-salmon-farm-through-a-longitudinal-farm-study
#6
Emiliano Di Cicco, Hugh W Ferguson, Angela D Schulze, Karia H Kaukinen, Shaorong Li, Raphaël Vanderstichel, Øystein Wessel, Espen Rimstad, Ian A Gardner, K Larry Hammell, Kristina M Miller
Heart and skeletal muscle inflammation (HSMI) is an emerging disease of marine-farmed Atlantic Salmon (Salmo salar), first recognized in 1999 in Norway, and later also reported in Scotland and Chile. We undertook a longitudinal study involving health evaluation over an entire marine production cycle on one salmon farm in British Columbia (Canada). In previous production cycles at this farm site and others in the vicinity, cardiac lesions not linked to a specific infectious agent or disease were identified. Histologic assessments of both live and moribund fish samples collected at the farm during the longitudinal study documented at the population level the development, peak, and recovery phases of HSMI...
2017: PloS One
https://www.readbyqxmd.com/read/28225687/reducing-iodine-contrast-volume-in-ct-angiography-of-the-abdominal-aorta-using-integrated-tube-potential-selection-and-weight-based-method-without-compromising-image-quality
#7
Rogerio Vasconcelos, Terri J Vrtiska, Thomas A Foley, Thanila A Macedo, Juan C Montoya Cardona, Eric E Williamson, Cynthia H McCollough, Joel G Fletcher
OBJECTIVE: The purpose of this study is to determine whether image quality was maintained when a weight-based protocol incorporating tube potential selection was used to select lower iodine contrast volumes for aortic CT angiography (CTA). MATERIALS AND METHODS: Patients with potentially decreased renal function underwent CTA performed with the iodinated contrast volume determined using a table incorporating different tube potentials and patient weights. The image quality of CTA examinations performed with a reduced iodine volume (hereafter known as "low-iodine CTA examinations"), internal control CTA examinations (i...
March 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28225313/efficacy-and-safety-of-a-new-topical-testosterone-replacement-gel-therapy-for-the-treatment-of-male-hypogonadism
#8
Glenn Cunningham, Laurence Belkoff, Gerald Brock, Mitchell Efros, Marc Gittelman, Dario Carrara, Anders Neijber, Masakazu Ando, Jules Mitchel
OBJECTIVE: Testosterone replacement therapy is indicated for male hypogonadism. This study aimed to evaluate the efficacy and safety of Testosterone gel 2% (Tgel) over 90-days. METHODS: This phase 3, open-label, non-comparator study was conducted in adult hypogonadal men (two consecutive fasting serum testosterone values <300 ng/dL and >86% subjects with symptoms consistent with testosterone deficiency). Subjects applied Tgel 23 mg/day (single pump-actuation using hands-free cap applicator)...
February 22, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28223940/reconsideration-of-serial-visual-reversal-learning-in-octopus-octopus-vulgaris-from-a-methodological-perspective
#9
Alexander Bublitz, Severine R Weinhold, Sophia Strobel, Guido Dehnhardt, Frederike D Hanke
Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the stimuli are reversed: the former positive becomes the negative stimulus and vice versa. If an animal improves its performance over reversals, it is ascribed advanced cognitive abilities. Reversal learning has been tested in octopus in a number of studies...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28223458/mutation-of-the-n-terminal-region-of-chikungunya-virus-capsid-protein-implications-for-vaccine-design
#10
Adam Taylor, Xiang Liu, Ali Zaid, Lucas Y H Goh, Jody Hobson-Peters, Roy A Hall, Andres Merits, Suresh Mahalingam
Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nucleolus. In encephalitic alphaviruses, nuclear translocation induces host cell transcriptional shutoff; however, the role of capsid protein nucleolar localization in arthritogenic alphaviruses remains unclear. Using recombinant enhanced green fluorescent protein (EGFP)-tagged expression constructs and CHIKV infectious clones, we describe a nucleolar localization sequence (NoLS) in the N-terminal region of capsid protein, previously uncharacterized in CHIKV...
February 21, 2017: MBio
https://www.readbyqxmd.com/read/28222871/evaluation-of-hypersensitivity-after-the-placement-of-metal-ceramic-crowns-cemented-with-two-luting-agents-long-term-results-of-a-prospective-clinical-study
#11
Carla Kozmacs, Katharina Schaper, Hans-Christoph Lauer, Andree Piwowarczyk
STATEMENT OF PROBLEM: Different luting materials are available for the cementation of fixed dental prostheses. Postcementation hypersensitivity is an occasional complication in the definitive delivery. How the choice of luting agent affects long-term postcementation sensitivity is unknown. PURPOSE: The purpose of this prospective, randomized, controlled, split-mouth clinical trial was to compare the hypersensitivity of 2 cementation methods for metal ceramic crowns...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28222834/acute-and-chronic-outcomes-of-gas-bubble-disease-in-a-colony-of-african-clawed-frogs-xenopus-laevis
#12
Julia Y Tsai, Stephen A Felt, Donna M Bouley, Sherril L Green
Gas-bubble disease occurs in aquatic species that are exposed to water that is supersaturated with gases. In February 2007, municipal water supersaturated with gas was inadvertently pumped into the vivarium's aquatic housing systems and affected approximately 450 adult female Xenopus laevis. The inflow of supersaturated water was stopped immediately, the holding tanks aggressively aerated, and all experimental manipulations and feeding ceased. Within the first 6 h after the event, morbidity approached 90%, and mortality reached 3...
February 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28222225/daylight-photodynamic-therapy-vs-conventional-photodynamic-therapy-as-skin-cancer-preventive-treatment-in-patients-with-face-and-scalp-cancerization-an-intra-individual-comparison-study
#13
Elena Sotiriou, Demetrios Ioannides, Fotini Vrani, Elizabeth Lazaridou, Efstratios Vakirlis, Aimilios Lallas, Zoe Apalla
BACKGROUND: Individuals with medical history of non-melanoma skin cancers (NMSCs) usually develop multiple and/or recurrent malignant lesions around the site of the primary neoplasm. The latter represents the clinical expression of the "field cancerization" theory; supporting the presence of multiple malignant clones of dysplastic keratinocytes over the entire epithelium that potentially can progress into clinical lesions. Taking into consideration that the burden of NMSCs on public health and health-care cost is high, adequate control of recurrences and management of field change is challenging...
February 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28220287/the-yield-of-initial-conventional-mri-in-115-cases-of-angiographically-confirmed-spinal-vascular-malformations
#14
Amgad El Mekabaty, Carlos A Pardo, Philippe Gailloud
MRI is the primary screening tool for patients with myelopathy. The decision to obtain additional imaging, notably spinal angiography, is generally based on initial MRI findings. This study retrospectively analyzed the yield of initial MRI in a cohort of patients with angiographically confirmed vascular malformations. MRI obtained at symptom onset was available in 115 patients with either high-flow (29 cases) or low-flow (86 cases) vascular malformations. MRI was classified as "positive" when the report mentioned a vascular malformation or "negative" when considered normal or when another diagnosis was suggested...
February 20, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28220264/treatment-of-stage-ii-medication-related-osteonecrosis-of-the-jaw-with-necrosectomy-and-autologous-bone-marrow-mesenchymal-stem-cells
#15
Pit Jacob Voss, Akihiko Matsumoto, Esteban Alvarado, Rainer Schmelzeisen, Fabian Duttenhöfer, Philipp Poxleitner
Treatment strategies for medication-related osteonecrosis of the jaw (MRONJ) remain controversial. Although the AAOMS suggests a conservative approach, a surgical management with necrosectomy is often required when conservative management has failed. Moreover, recent studies have shown promising results using an early stage surgical treatment. Over the past decade, cell-based bone regeneration utilizing bone marrow mesenchymal stem cells (MSCs) received increased attention. MSCs are known to promote wound healing and induce new bone formation in compromised tissue...
February 20, 2017: Odontology
https://www.readbyqxmd.com/read/28219714/relationship-between-physical-activity-and-hip-pain-in-persons-with-and-without-cam-or-pincer-morphology-a-population-based-case-control-study
#16
Jacek A Kopec, Jolanda Cibere, Linda C Li, Charlie Zhang, Morgan Barber, Hong Qian, Hubert Wong, Gavin Steininger, Helen Prlic, Jacqueline Simatovic, Charles Ratzlaff, Eric C Sayre, Joanna Ye, Bruce B Forster, John M Esdaile
OBJECTIVES: The purpose of the study was to determine if physical activity (PA) is a risk factor for persistent or recurrent hip pain in young and middle-aged persons with and without radiographic findings of cam or pincer morphology (CPM). METHODS: A population sample of persons aged 20-49 with (cases) and without (controls) hip pain in Metro Vancouver, Canada, was selected through random digit dialing. Self-reported PA was expressed as average energy expenditure (MET-hours) per year, over lifetime...
February 17, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28218888/using-clinical-signs-and-symptoms-for-medical-management-of-radiation-casualties-2015-nato-exercise
#17
H Dörr, M Abend, W F Blakely, D L Bolduc, D Boozer, T Costeira, T Dant, A De Amicis, S De Sanctis, M Dondey, M Drouet, F Entine, S Francois, G Gagna, N Guitard, F Hérodin, M Hoefer, A Lamkowski, G La Sala, F Lista, P Loiacono, M Majewski, P Martigne, D Métivier, X Michel, J Pateux, J Pejchal, G Reeves, D Riccobono, Z Sinkorova, L Soyez, D Stricklin, A Tichy, M Valente, C R Woodruff, L Zarybnicka, M Port
The utility of early-phase (≤5 days) radiation-induced clinical signs and symptoms (e.g., vomiting, diarrhea, erythema and changes in blood cell counts) was examined for the prediction of later occurring acute radiation syndrome (ARS) severity and the development of medical management strategies. Medical treatment protocols for radiation accident victims (METREPOL) was used to grade ARS severities, which were assigned response categories (RCs). Data on individuals (n = 191) with mild (RC1, n = 45), moderate (RC2, n = 19), severe (RC3, n = 20) and fatal (RC4, n = 18) ARS, as well as nonexposed individuals (RC0, n = 89) were generated using either METREPOL (n = 167) or the system for evaluation and archiving of radiation accidents based on case histories (SEARCH) database (n = 24), the latter comprised of real-case descriptions...
February 20, 2017: Radiation Research
https://www.readbyqxmd.com/read/28218373/the-use-of-polycarbonate-urethane-as-an-acetabular-shell-bearing-surface-a-5-year-prospective-study
#18
Sabine Mai, Burkhard Mai, Werner E Siebert
AIM: To evaluate the clinical performance of a polycarbonate-urethane liner as a bearing material inside a cobalt-chrome acetabular shell. METHODS: Between December 2007 and July 2011, this material combination was used in 27 total hip replacement patients, most of whom had an indication of osteoarthritis. This report focuses on the first 5-year results of the clinical use of this material combination in the TriboFit® Hip System. RESULTS: Mean Harris Hip Score showed significant improvement from 40 to 86 after 5 years, similar to studies in the literature...
February 8, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28217818/psychosocial-needs-and-interventions-for-heart-failure-patients-and-families-receiving-palliative-care-support-a-systematic-review
#19
REVIEW
John G Cagle, Morgan Bunting, Anne Kelemen, Joonyup Lee, Dorothy Terry, Ryan Harris
Although diseases of the heart are the leading cause of death in the USA, palliative care research has largely focused on populations of cancer patients. However, a diagnosis of heart failure differs substantially than that of cancer. They differ in terms of signs and symptoms, disease trajectories, treatment options, stigma, and prognosis. Additionally, the populations affected by these differing illnesses are also unique in a number of fundamental ways. Based on these differences, it is reasonable to hypothesize that palliative care patients with heart failure, and their families, have a distinct set of psychosocial needs...
February 20, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28217545/comparative-clinical-and-radiographic-evaluation-of-mineralized-cancellous-bone-allograft-puros-%C3%A2-and-autogenous-bone-in-the-treatment-of-human-periodontal-intraosseous-defects-6-months-follow-up-study
#20
B Ravinder Reddy, J Sudhakar, Nichenametla Rajesh, V Sandeep, Y Muralidhar Reddy, W R Gnana Sagar
AIMS: Several materials have been introduced as bone grafts, i.e., autografts, allograft, xenografts, and alloplastic grafts, and studies have shown them to produce greater clinical bone defect fill than open flap debridement alone. The aim of this clinical and radiological 6-month study was to compare and evaluate the clinical outcome of deep intraosseous defects following reconstructive surgery with the use of mineralized cancellous bone allograft (Puros(®)) or autogenous bone. MATERIALS AND METHODS: Ten patients with 12 sites exhibiting signs of moderate generalized chronic periodontitis were enrolled in the study...
December 2016: Journal of International Society of Preventive & Community Dentistry
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