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https://www.readbyqxmd.com/read/29332922/role-of-gene-polymorphisms-haplotypes-and-plasma-level-of-tgf-%C3%AE-1-in-susceptibility-to-in-stent-restenosis-following-coronary-implantation-of-bare-metal-stent-in-chinese-han-patients
#1
Hai-Jian Chen, Ni Mo, Yan-Feng Zhang, Guo-Zhu Su, Han-Dong Wu, Fang Pei
Transforming growth factor (TGF)-β1 has been implicated in the pathogenesis of restenosis. However, the role of TGF-β1 polymorphisms in development of in-stent restenosis (ISR) after coronary bare metal stent (BMS) implantation in Chinese Han population has not been reported to date. The aim of this study was to explore the association between TGF-β1 gene polymorphisms (-509C/T and 869T/C) and its plasma level in Chinese Han patients with BMS-ISR.We investigated 419 patients after successful coronary stent placement...
January 15, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29331986/sex-differences-in-impact-of-coronary-artery-calcification-to-predict-coronary-artery-disease
#2
Yoko M Nakao, Yoshihiro Miyamoto, Masahiro Higashi, Teruo Noguchi, Mitsuru Ohishi, Isao Kubota, Hiroyuki Tsutsui, Tomohiro Kawasaki, Yutaka Furukawa, Michihiro Yoshimura, Hideaki Morita, Kunihiro Nishimura, Akiko Kada, Yoichi Goto, Tomonori Okamura, Chuwa Tei, Hitonobu Tomoike, Hiroaki Naito, Satoshi Yasuda
OBJECTIVE: To assess sex-specific differences regarding use of conventional risks and coronary artery calcification (CAC) to detect coronary artery disease (CAD) using coronary CT angiography (CCTA). METHODS: The Nationwide Gender-specific Atherosclerosis Determinants Estimation and Ischemic Cardiovascular Disease Prospective Cohort study is a prospective, multicentre, nationwide cohort study. Candidates with suspected CAD aged 50-74 years enrolled from 2008 to 2012...
January 13, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29330042/differences-in-the-ct-findings-between-vulnerable-plaque-and-culprit-lesions-in-acute-coronary-syndrome
#3
Eun Ju Chun, Jin Hee Han, Seung Min Yoo, Hwa Yeon Lee, In Sup Song, Charles S White
BACKGROUND: The CT finding of "vulnerable plaque" is widely regarded as similar to that of a culprit lesion in an acute coronary syndrome (ACS). However, this hypothesis may not be accurate, since "vulnerable plaques" may substantially change their morphology when they rupture to cause an ACS. METHODS: We retrospectively evaluated coronary CT angiography data sets of 25 patients with ACS who had vulnerable (n = 10) or culprit plaques (n = 15). We analyzed CT features including positive remodeling (PR), low attenuation plaque (LAP), the napkin ring sign (NRS), degree of stenosis (normal, <50%, 50-99%, 100%), and myocardial hypoperfusion in the left ventricle...
January 5, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29324489/comparing-methods-for-cardiac-output-intraoperatively-doppler-derived-cardiac-output-measured-with-3-dimensional-echocardiography-is-not-interchangeable-with-cardiac-output-by-pulmonary-catheter-thermodilution
#4
Karin Graeser, Mikhail Zemtsovski, Klaus F Kofoed, Matilde Winther-Jensen, Jens C Nilsson, Jesper Kjaergaard, Hasse Møller-Sørensen
BACKGROUND: Estimation of cardiac output (CO) is essential in the treatment of circulatory unstable patients. CO measured by pulmonary artery catheter thermodilution is considered the gold standard but carries a small risk of severe complications. Stroke volume and CO can be measured by transesophageal echocardiography (TEE), which is widely used during cardiac surgery. We hypothesized that Doppler-derived CO by 3-dimensional (3D) TEE would agree well with CO measured with pulmonary artery catheter thermodilution as a reference method based on accurate measurements of the cross-sectional area of the left ventricular outflow tract...
January 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29320864/diagnostic-performance-of-static-single-scan-stress-perfusion-cardiac-computed-tomography-in-detecting-hemodynamically-significant-coronary-artery-stenosis-a-comparison-with-combined-invasive-coronary-angiography-and-cardiovascular-magnetic-resonance-myocardial
#5
Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Mi Young Kim, Je Kyoun Shin, Sung Min Ko
Background Non-invasive anatomical and physiological evaluations of coronary artery disease (CAD) may be obtained with static single-scan stress perfusion cardiac computed tomography (SSPCT). Purpose To determine the diagnostic performance of static SSPCT for identifying hemodynamically significant CAD. Material and Methods This prospective study included 29 patients with suspected or known CAD who underwent static SSPCT, cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI), and invasive coronary angiography (ICA)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29311033/lesion-specific-and-vessel-related-determinants-of-fractional-flow-reserve-beyond-coronary-artery-stenosis
#6
Amir Ahmadi, Jonathon Leipsic, Kristian A Øvrehus, Sara Gaur, Emilia Bagiella, Brian Ko, Damini Dey, Gina LaRocca, Jesper M Jensen, Hans Erik Bøtker, Stephan Achenbach, Bernard De Bruyne, Bjarne L Nørgaard, Jagat Narula
OBJECTIVES: The aims of the present study were: 1) to investigate the contribution of the extent of luminal stenosis and other lesion composition-related factors in predicting invasive fractional flow reserve (FFR); and 2) to explore the distribution of various combinations of morphological characteristics and the severity of stenosis among lesions demonstrating normal and abnormal FFR. BACKGROUND: In patients with stable ischemic heart disease, FFR-guided revascularization, as compared with medical therapy alone, is reported to improve outcomes...
January 2, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29310329/impact-of-iterative-reconstruction-vs-filtered-back-projection-on-image-quality-in-320-slice-ct-coronary-angiography-insights-from-the-core320-multicenter-study
#7
Ahmed Fareed, Andrea L Vavere, Elke Zimmermann, Yutaka Tanami, Chloe Steveson, Matthew Matheson, Narinder Paul, Melvin Clouse, Christopher Cox, João A C Lima, Armin Arbab-Zadeh
Iterative reconstruction has been shown to reduce image noise compared with traditional filtered back projection with quantum denoising software (FBP/QDS+) in CT imaging but few comparisons have been made in the same patients without the influence of interindividual factors. The objective of this study was to investigate the impact of adaptive iterative dose reduction in 3-dimensional (AIDR 3D) and FBP/QDS+-based image reconstruction on image quality in the same patients.We randomly selected 100 patients enrolled in the coronary evaluation using 320-slice CT study who underwent CT coronary angiography using prospectively electrocardiogram triggered image acquisition with a 320-detector scanner...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29304060/effectiveness-of-automatic-tube-potential-selection-with-tube-current-modulation-in-coronary-ct-angiography-for-obese-patients-comparison-with-a-body-mass-index-based-protocol-using-the-propensity-score-matching-method
#8
Hong Seon Lee, Young Joo Suh, Kyunghwa Han, Jin Young Kim, Suyon Chang, Dong Jin Im, Yoo Jin Hong, Hye-Jeong Lee, Jin Hur, Young Jin Kim, Byoung Wook Choi
BACKGROUND: Reduced image quality from increased X-ray scatter and image noise can be problematic when coronary computed tomography angiography (CCTA) imaging is performed in obese patients. The aim of this study was to compare the image quality and radiation dose obtained using automatic tube potential selection with tube current modulation (APSCM) with those obtained using a body mass index (BMI)-based protocol for CCTA in obese patients. METHODS: A total of 203 consecutive obese (BMI > 30 kg/m2) patients were retrospectively enrolled, of whom 96 underwent CCTA with APSCM and 107 underwent a BMI-based protocol...
2018: PloS One
https://www.readbyqxmd.com/read/29301713/the-coronary-artery-disease-reporting-and-data-system-cad-rads-prognostic-and-clinical-implications-associated-with-standardized-coronary-computed-tomography-angiography-reporting
#9
Joe X Xie, Ricardo C Cury, Jonathon Leipsic, Matthew T Crim, Daniel S Berman, Heidi Gransar, Matthew J Budoff, Stephan Achenbach, Bríain Ó Hartaigh, Tracy Q Callister, Hugo Marques, Ronen Rubinshtein, Mouaz H Al-Mallah, Daniele Andreini, Gianluca Pontone, Filippo Cademartiri, Erica Maffei, Kavitha Chinnaiyan, Gilbert Raff, Martin Hadamitzky, Joerg Hausleiter, Gudrun Feuchtner, Allison Dunning, Augustin DeLago, Yong-Jin Kim, Philipp A Kaufmann, Todd C Villines, Benjamin J W Chow, Niree Hindoyan, Millie Gomez, Fay Y Lin, Erica Jones, James K Min, Leslee J Shaw
OBJECTIVES: This study sought to assess clinical outcomes associated with the novel Coronary Artery Disease-Reporting and Data System (CAD-RADS) scores used to standardize coronary computed tomography angiography (CTA) reporting and their potential utility in guiding post-coronary CTA care. BACKGROUND: Clinical decision support is a major focus of health care policies aimed at improving guideline-directed care. Recently, CAD-RADS was developed to standardize coronary CTA reporting and includes clinical recommendations to facilitate patient management after coronary CTA...
January 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29296166/multimodal-imaging-for-the-assessment-of-a-cardiac-mass-a-case-of-primary-cardiac-sarcoma
#10
Benjamin Abels, Steffen Pfeiffer, Jana Stix, Johannes Schwab
We present a case of an 85-year-old patient who underwent clinical work-up for chronic heart failure, acute coronary syndrome, and pulmonary embolism, until she was diagnosed with a cardiac mass that was histologically identified as sarcoma. The aim of this educational case report is to raise awareness of cardiac masses and to point out diagnostic hints towards a cardiac tumor on chest X-ray, coronary angiography, echocardiography, and chest CT. Moreover, the vital role of cardiac magnetic resonance for the diagnosis of a cardiac mass is highlighted...
November 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29278631/prevalence-of-coronary-artery-anomalies-detected-by-coronary-ct-angiography-in-canton-sarajevo-bosnia-and-herzegovina
#11
Fuad Zukić, Miro Miljko, Sandra Vegar-Zubović, Adi Behmen, Antonela Krasić Arapović
BACKGROUND: Coronary artery anomalies (CAAs) are congenital variations of one or more of the coronary arteries and they are an uncommon but important cause of chest pain and, in some cases, sudden cardiac death. Anomalies of coronary arteries may be found incidentally in 0.3-1% of healthy individuals. The three types of coronary artery anomalies are anomalies of origin, anomalies of course and anomalies of termination. The purpose of our study was to estimate the frequency of CAAs in Canton Sarajevo, B&H, and to deteremine the prevalence of origin, course and termination anomalies of coronary arteries...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29275779/the-predictive-value-of-positive-affect-and-type-d-personality-for-adverse-cardiovascular-clinical-outcomes-in-patients-with-non-obstructive-coronary-artery-disease
#12
Maria T Bekendam, Willem J Kop, Simone Barzilay, Jos W Widdershoven, Wilbert Aarnoudse, Johan Denollet, Paula M C Mommersteeg
BACKGROUND: Patients with non-obstructive coronary artery disease (NOCAD) continue to experience disabling symptoms. Positive affect (PA) has shown a cardioprotective potential. Type D personality has previously been shown to have a deleterious effect on adverse outcomes in diverse cardiac populations. Little is known about the predictive value of PA and Type D personality for long-term outcomes in NOCAD patients. The aim was to investigate the effect of PA and Type D personality on clinical outcomes...
January 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29261462/contrast-media-for-coronary-ct-angiography-should-an-iso-osmolar-agent-be-used
#13
U Joseph Schoepf
No abstract text is available yet for this article.
January 2018: Radiology
https://www.readbyqxmd.com/read/29260577/coronary-computed-tomography-in-heart-transplant-patients-detection-of-significant-stenosis-and-cardiac-allograft-vasculopathy-image-quality-and-radiation-dose
#14
Anne Günther, Lars Aaberge, Andreas Abildgaard, Asgrimur Ragnarsson, Thor Edvardsen, Jarl Jakobsen, Rune Andersen
Background Cardiac allograft vasculopathy (CAV) is an accelerated form of atherosclerosis unique to heart transplant (HTX) patients. Purpose To investigate the detection of significant coronary artery stenosis and CAV, determinants of image quality, and the radiation dose in coronary computed tomography angiography (CCTA) of HTX patients with 64-slice multidetector CT (64-MDCT). Material and Methods Fifty-two HTX recipients scheduled for invasive coronary angiography (ICA) were prospectively enrolled and underwent CCTA before ICA with intravascular ultrasound (IVUS)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29248657/comprehensive-cardiac-ct-with-myocardial-perfusion-imaging-versus-functional-testing-in-suspected-coronary-artery-disease-the-multicenter-randomized-crescent-ii-trial
#15
Marisa Lubbers, Adriaan Coenen, Marcel Kofflard, Tobias Bruning, Bas Kietselaer, Tjebbe Galema, Marc Kock, Andre Niezen, Marco Das, Marco van Gent, Ewout-Jan van den Bos, Leon van Woerkens, Paul Musters, Suze Kooij, Fay Nous, Ricardo Budde, Miriam Hunink, Koen Nieman
OBJECTIVES: This study sought to assess the effectiveness, efficiency, and safety of a tiered, comprehensive cardiac computed tomography (CT) protocol in comparison with functional testing. BACKGROUND: Although CT angiography accurately rules out coronary artery disease (CAD), incorporation of CT myocardial perfusion imaging as part of a tiered diagnostic approach could improve the clinical value and efficiency of cardiac CT in the diagnostic work-up of patients with angina pectoris...
December 8, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29248654/value-of-myocardial-perfusion-assessment-with-coronary-computed-tomography-angiography-in-patients-with-recent-acute-onset-chest-pain
#16
Mathias H Sørgaard, Jesper J Linde, J Tobias Kühl, Henning Kelbæk, Jens D Hove, Gitte G Fornitz, Tem B S Jørgensen, Merete Heitmann, Charlotte Kragelund, Thomas F Hansen, Jawdat Abdulla, Thomas Engstrøm, Jan S Jensen, Yaffah T Wiegandt, Dan E Høfsten, Lars V Køber, Klaus F Kofoed
OBJECTIVES: The authors sought to perform a randomized controlled trial to evaluate the clinical efficacy of combined examination with coronary computed tomography angiography (CTA) and computed tomography perfusion imaging (CTP) compared to coronary CTA alone. BACKGROUND: Stress myocardial CTP may increase diagnostic specificity when added to coronary CTA in patients suspected of having ischemic heart disease. METHODS: Patients recently hospitalized for acute-onset chest pain, in whom acute coronary syndrome had been ruled out by normal electrocardiograms, normal troponin levels, and relief of symptoms, and who had a clinical indication for outpatient noninvasive testing, were screened for inclusion in the CATCH-2 (CArdiac cT in the treatment of acute CHest pain 2) trial (NCT02014311)...
December 8, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29248645/diagnostic-value-of-transluminal-attenuation-gradient-for-the-presence-of-ischemia-as-defined-by-fractional-flow-reserve-and-quantitative-positron-emission-tomography
#17
Michiel J Bom, Roel S Driessen, Wynand J Stuijfzand, Pieter G Raijmakers, Cornelis C Van Kuijk, Adriaan A Lammertsma, Albert C van Rossum, Niels van Royen, Juhani Knuuti, Maija Mäki, Koen Nieman, James K Min, Jonathon A Leipsic, Ibrahim Danad, Paul Knaapen
OBJECTIVES: The aim of this study was to investigate the incremental diagnostic value of transluminal attenuation gradient (TAG), TAG with corrected contrast opacification (TAG-CCO), and transluminal diameter gradient (TDG) over coronary computed tomography angiography (CTA)-derived diameter stenosis alone for the identification of ischemia as defined by both the invasive reference standard fractional flow reserve (FFR) and the noninvasive reference standard quantitative positron emission tomography (PET)...
December 8, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29247351/round-the-clock-performance-of-coronary-ct-angiography-for-suspected-acute-coronary-syndrome-results-from-the-beacon-trial
#18
Marisa M Lubbers, Admir Dedic, Akira Kurata, Marcel Dijkshoorn, Jeroen Schaap, Jeroen Lammers, Evert J Lamfers, Benno J Rensing, Richard L Braam, Hendrik M Nathoe, Johannes C Post, Pleunie P Rood, Carl J Schultz, Adriaan Moelker, Mohamed Ouhlous, Bas M van Dalen, Eric Boersma, Koen Nieman
OBJECTIVE: To assess the image quality of coronary CT angiography (CCTA) for suspected acute coronary syndrome (ACS) outside office hours. METHODS: Patients with symptoms suggestive of an ACS underwent CCTA at the emergency department 24 hours, 7 days a week. A total of 118 patients, of whom 89 (75 %) presented during office hours (weekdays between 07:00 and 17:00) and 29 (25 %) outside office hours (weekdays between 17:00 and 07:00, weekends and holidays) underwent CCTA...
December 15, 2017: European Radiology
https://www.readbyqxmd.com/read/29246551/comparative-effectiveness-of-coronary-screening-in-heart-valve-surgery-computed-tomography-versus-conventional-coronary-angiography
#19
Wonjae Lee, Joon Bum Kim, Dong Hyun Yang, Cherry Kim, Jihoon Kim, Min Ho Ju, Ho Jin Kim, Joon-Won Kang, Sung-Ho Jung, Young-Hak Kim, Suk Jung Choo, Cheol Whan Lee, Cheol Hyun Chung, Jae Won Lee, Tae-Hwan Lim
BACKGROUND: Although conventional coronary angiography (CAG) is considered the gold standard for coronary artery disease (CAD) screening in the setting of heart valve surgery, coronary artery computed tomography angiography (CCTA) has emerged as an alternative modality. This study was conducted to evaluate the clinical outcomes of CCTA compared with conventional CAG for CAD screening in patients undergoing heart valve surgery. METHODS: A total of 3150 consecutive patients aged >40 years or with coronary risk factors undergoing elective valve operations between 2001 and 2015 were evaluated...
November 14, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29239297/dynamic-flow-imaging-using-320-detector-row-ct-and-motion-coherence-analysis-in-coronary-aneurysms-associated-with-kawasaki-disease
#20
Yamato Shimomiya, Michinobu Nagao, Yuzo Yamasaki, Takashi Shirasaka, Masatoshi Kondo, Tsukasa Kojima, Akihiro Nishie, Kenichiro Yamamura, Hiroshi Honda
Introduction We propose a new dynamic flow imaging using 320-detector row CT, and investigate the assessment of coronary flow in aneurysms of Kawasaki disease in adulthood. METHODS: Six patients with Kawasaki disease and coronary aneurysms associated (26.7 years old) and six controls were enrolled. Dynamic coronary CT angiography with 320-row CT was continuously performed at mid-diastole throughout 15-25 cardiac cycles with prospective Electrocardiogram gating after injection of contrast media...
December 14, 2017: Cardiology in the Young
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