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https://www.readbyqxmd.com/read/29777908/breast-cancer-in-the-gcc-countries-a-focus-on-brca1-2-and-non-brca1-2-genes
#1
REVIEW
Sumaya Rahman, Hatem Zayed
The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with very high consanguineous marriage rates. Although breast cancer is on the rise in the GCC countries, there are dearth of studies reporting on the genetic epidemiology of breast cancer. In this study, we investigated the frequency of BRCA1/2 and non-BRCA1/2 mutations in breast cancer patients in the GCC countries...
May 16, 2018: Gene
https://www.readbyqxmd.com/read/29772398/molecular-epidemiology-and-characterization-of-picobirnaviruses-in-small-ruminant-populations-in-india
#2
Yashpal Singh Malik, Shubhankar Sircar, Kuldeep Dhama, Rashmi Singh, Souvik Ghosh, Krisztián Bányai, Anastasia N Vlasova, Touil Nadia, Raj Kumar Singh
Picobirnavirus (PBV) is recognized as a putative cause of diarrhea and respiratory illnesses. Although PBV has been reported in several mammalian (including humans) and avian host species, data pertaining to its presence in small ruminants are limited. We report, here, PBV infection in small ruminants (ovine and caprine), in India. From January 2015 to December 2017, 400 samples were tested for the presence of PBV, using an RT-PCR assay specific for the genome segment-2. The overall rate of PBV infection was 35...
May 14, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29764376/methicillin-resistant-staphylococcus-aureus-in-emergency-department-patients-in-the-united-arab-emirates
#3
Muna Al Jalaf, Hanan Fadali, Rasha Alanee, Firas Najjar, Zulfa Al Deesi, Rania M Seliem, Eric J Nilles
BACKGROUND: Since the 1990s, community-associated methicillin resistant staphylococcus aureus (CA-MRSA) has emerged as an important global cause of skin and soft tissue infections. Little is known about the epidemiology of this pathogen in the Middle East. METHODS: We conducted a prospective observational study in a single large teaching hospital in Dubai to identify the incidence of community-acquired methicillin resistant staphylococcus aureus (MRSA) among ambulatory patients presenting with purulent skin and soft tissue infections...
May 15, 2018: BMC Emergency Medicine
https://www.readbyqxmd.com/read/29755807/assessing-the-prevalence-and-incidence-of-asthma-and-chronic-obstructive-pulmonary-disease-in-the-eastern-mediterranean-region
#4
Mohammadreza Masjedi, Elaheh Ainy, Faried Zayeri, Rogayeh Paydar
OBJECTIVES: This study conducted in 2016 aimed to assess the prevalence and incidence of asthma and chronic obstructive pulmonary disease (COPD) in the Eastern Mediterranean Region (EMR). MATERIAL AND METHODS: A meta-analysis to evaluate the published research relating to asthma and COPD was conducted using data from 23 EMR Office (EMRO) countries and searching using the web of science, PubMed, SciVerse Scopus, Google scholar, and MEDLINE databases. The keywords entered were all EMRO countries (Afghanistan, Bahrain, Djibouti, Egypt, Islamic republic Iran, Iraq, Jordan, Kuwait, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arab, Somalia, Sudan, Syrian Arab Republic, Tunisia, the United Arab Emirates, Yemen republic, and Cyprus) and asthma OR chronic obstructive pulmonary disease (COPD) OR (chronic bronchitis)...
April 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29751756/prevalence-of-asthma-among-the-adult-general-population-of-five-middle-eastern-countries-results-of-the-snapshot-program
#5
Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz, Abdelkader El Hasnaoui
BACKGROUND: Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated. The SNAPSHOT program was conducted to obtain updated information. METHODS: SNAPSHOT is a cross-sectional epidemiological program carried out in five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia, and the United Arab Emirates, the latter three grouped into a Gulf cluster) to collect data on asthma, allergic rhinitis, benign prostatic hyperplasia and bipolar disorder...
May 11, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29738011/prevalence-of-hepatitis-b-c-and-hiv-among-patients-attending-a-teaching-dental-hospital-a-7-year-retrospective-study-from-the-united-arab-emirates
#6
Suhail H Al-Amad
OBJECTIVES: To determine the seroprevalence and case characteristics of hepatitis B, C and human immunodeficiency virus (HIV), and their transmissibility from patients to dental personnel following percutaneous and mucocutaneous injuries. METHODS: All incidents of sharp and splash injuries reported between January 2010 and January 2017 were retrospectively reviewed and analyzed. Descriptive statistics were calculated using the Statistical Package for the Social Science (SPSS)...
May 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29737819/eating-disorders-and-body-image-concerns-as-influenced-by-family-and-media-among-university-students-in-sharjah-uae
#7
Hadia Radwan, Hayder A Hasan, Lina Najm, Sara Zaurub, Faridah Jami, Fahimeh Javadi, Lina Adeeb Deeb, Amani Iskandarani
BACKGROUND AND OBJECTIVES: Eating disorders (ED) can be influenced by psychological and socio-cultural factors. The aim of this study was to explore the association between parental and media influences and body image concerns as factors in the onset of ED. METHODS AND STUDY DESIGN: A cross-sectional study was conducted among 662 students (407 women and 255 men) attending one of three universities in United Arab Emirates (UAE). The study employed an online self-administered questionnaire with validated scales: Eating Attitudes Test-26 (EAT-26), Body Shape Questionnaire (BSQ), Media Influences Scale, and Family Influences Scale (FIS)...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29732592/transcranial-doppler-ultrasound-in-peninsular-arab-patients-with-sickle-cell-disease
#8
Adekunle Adekile, Meaad Hassan, Akram Asbeutah, Mohamed Al-Hinai, Omar Trad, Nayef Farhan
OBJECTIVES: Transcranial Doppler ultrasound is used to identify patients with sickle cell disease (SCD) at risk for stroke. We performed transcranial Doppler studies in patients from 4 countries in the Arabian Peninsula (Kuwait, Oman, Iraq, and United Arab Emirates) to document the prevalence of abnormal transcranial Doppler findings. METHODS: The patients were recruited from outpatient clinics and studied in a steady state. Transcranial Doppler examinations were performed with standard equipment by experienced operators...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29718919/climate-change-impacts-on-marine-biodiversity-fisheries-and-society-in-the-arabian-gulf
#9
Colette C C Wabnitz, Vicky W Y Lam, Gabriel Reygondeau, Lydia C L Teh, Dalal Al-Abdulrazzak, Myriam Khalfallah, Daniel Pauly, Maria L Deng Palomares, Dirk Zeller, William W L Cheung
Climate change-reflected in significant environmental changes such as warming, sea level rise, shifts in salinity, oxygen and other ocean conditions-is expected to impact marine organisms and associated fisheries. This study provides an assessment of the potential impacts on, and the vulnerability of, marine biodiversity and fisheries catches in the Arabian Gulf under climate change. To this end, using three separate niche modelling approaches under a 'business-as-usual' climate change scenario, we projected the future habitat suitability of the Arabian Gulf (also known as the Persian Gulf) for 55 expert-identified priority species, including charismatic and non-fish species...
2018: PloS One
https://www.readbyqxmd.com/read/29717269/multiple-genetic-variations-confer-risks-for-obesity-and-type-2-diabetes-mellitus-in-arab-descendants-from-uae
#10
Wael Osman, Guan K Tay, Habiba Alsafar
BACKGROUND: The United Arab Emirates (UAE) is one of the countries most threatened with obesity. Here we investigated associations between hundreds of single-nucleotide polymorphisms (SNPs) and the following obesity indicators: body mass index (BMI), waist circumference (WC), and height. We also investigated the associations between obesity-related genes with type 2 diabetes mellitus (T2DM). METHODS: We tested 87, 58, and 586 SNPs in a previous genome-wide significance level for associations with BMI (n = 880), WC (n = 455), and height (n = 897), respectively...
March 12, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29717208/high-prevalence-of-diabetes-among-migrants-in-the-united-arab-emirates-using-a-cross-sectional-survey
#11
Nabil Sulaiman, Salah Albadawi, Salah Abusnana, Maisoon Mairghani, Amal Hussein, Fatheya Al Awadi, Abdulrazak Madani, Paul Zimmet, Jonathan Shaw
In 2011, the United Arab Emirates (UAE) had the 10th highest diabetes prevalence globally, but this was based on data that excluded migrants who comprise 80% of the population. This study assessed diabetes prevalence across the UAE population. A random sample of migrants was recruited from the visa renewal centers. Data were collected using interviews, anthropometric measurements and fasting blood for glucose, lipids and genetic analyses. 2724 adults completed the questionnaires and blood tests. Of these, 81% were males, 65% were ≤40 years old and 3% were above 60 years...
May 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29706469/what-drives-intentional-overdose-with-non-prescription-drugs-a-cross-sectional-study
#12
K A Al Kubaisi, M D SteCroix, D Vinson, M N Hassan, M R Baig, S L Sharif, A R Abduelkarem
BACKGROUND: Use of overdosage of Non-Prescription Drugs (NPD) among university students is a serious public health issue. However, there are no extensive studies that measured the prevalence of taking more than the recommended dose of NPD and/or identified the risk associated with this behavior among university students. OBJECTIVES: This study was undertaken to assess the prevalence and associated risks of self-overdosage with NPDs in university students in United Arab Emirates (UAE)...
April 26, 2018: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29698434/evaluation-of-a-photographic-food-atlas-as-a-tool-for-quantifying-food-portion-size-in-the-united-arab-emirates
#13
Habiba I Ali, Carine Platat, Najoua El Mesmoudi, Mohamed El Sadig, Ihab Tewfik
Although, United Arab Emirates (UAE) has one of the highest prevalence of overweight, obesity and type 2 diabetes in the world, however, validated dietary assessment aids to estimate food intake of individuals and populations in the UAE are currently lacking. We conducted two observational studies to evaluate the accuracy of a photographic food atlas which was developed as a tool for food portion size estimation in the UAE. The UAE Food Atlas presents eight portion sizes for each food. Study 1 involved portion size estimations of 13 food items consumed during the previous day...
2018: PloS One
https://www.readbyqxmd.com/read/29690112/filling-the-gap-of-whip-spider-distribution-in-asia-phrynichus-persicus-sp-n-arachnida-amblypygi-a-new-phrynichidae-from-iran
#14
Gustavo Silva De Miranda, Alireza Zamani
The whip spider genus Phrynichus (Phrynichidae, Amblypygi) is widely distributed in Africa, the Arabian Peninsula and Asia with a total of 17 species. No records, however, are known from several countries in the Middle East. Here we provide the first record of a whip spider from Iran (Ilam Province), with the description and illustration of a new species, Phrynichus persicus sp. n. This discovery fills a gap in the distribution of the group that is known from both sides of this biogeographically interesting region and is also the northernmost record of the family Phrynichidae...
April 23, 2018: Zootaxa
https://www.readbyqxmd.com/read/29689483/evaluation-of-background-radiation-dose-contributions-in-the-united-arab-emirates
#15
Braden Goddard, Emmanuel Bosc, Sarra Al Hasani, Cody Lloyd
The natural background radiation consists of three main components; cosmic, terrestrial, and skyshine. Although there are currently methods available to measure the total dose rate from background radiation, no established methods exist that allow for the measurement of each component the background radiation. This analysis consists of a unique methodology in which the dose rate contribution from each component of the natural background radiation is measured and calculated. This project evaluates the natural background dose rate in the Abu Dhabi City region from all three of these components using the developed methodology...
April 21, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29688032/setting-up-an-epathology-service-at-cleveland-clinic-abu-dhabi-joint-collaboration-with-cleveland-clinic-united-states
#16
Ayoub Nahal, Crystal Mildred O Batac, Renee J Slaw, Thomas W Bauer
CONTEXT: - The production of whole slide images is the most advanced form of digital pathology, in which a high-resolution digital scanner is used to rapidly scan glass microscope slides and produce a computer-generated whole slide image that can be saved, stored in a network-attached storage device, and accessed through slide management software within the hospital domain and remotely by authorized users. Digital transformation of glass slides has revolutionized the practice of anatomic pathology by facilitating and expediting consultative services, improving clinical workflow, and becoming an indispensable tool in education and research...
April 24, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29685658/novel-founder-intronic-variant-in-slc39a14-in-two-families-causing-manganism-and-potential-treatment-strategies
#17
Lance H Rodan, Marissa Hauptman, Alissa M D'Gama, Anita E Qualls, Siqi Cao, Karin Tuschl, Fatma Al-Jasmi, Jozef Hertecant, Susan J Hayflick, Marianne Wessling-Resnick, Edward T Yang, Gerard T Berry, Andrea Gropman, Alan D Woolf, Pankaj B Agrawal
Congenital disorders of manganese metabolism are rare occurrences in children, and medical management of these disorders is complex and challenging. Homozygous exonic mutations in the manganese transporter SLC39A14 have recently been associated with a pediatric-onset neurodegenerative disorder characterized by brain manganese accumulation and clinical signs of manganese neurotoxicity, including parkinsonism-dystonia. We performed whole exome sequencing on DNA samples from two unrelated female children from the United Arab Emirates with progressive movement disorder and brain mineralization, identified a novel homozygous intronic mutation in SLC39A14 in both children, and demonstrated that the mutation leads to aberrant splicing...
April 6, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29673847/challenges-in-the-management-of-type-2-diabetes-among-native-women-in-the-united-arab-emirates
#18
Walaa Abuelmagd, Bachar Afandi, Helle Håkonsen, Seham Khmidi, Else-Lydia Toverud
AIM: To investigate type 2 diabetes mellitus (T2DM) management in native female patients in the United Arab Emirates (UAE). METHODS: Ninety women from the outpatient diabetes clinic at Tawam Hospital, UAE, were interviewed face-to-face using a structured questionnaire. Glycated hemoglobin (HbA1c), blood pressure, lipid panel, weight and body mass index (BMI) were extracted from medical records. RESULTS: Mean age was 57.5 (SD:12.7) years. Forty-five participants (50...
April 16, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29667204/public-stigma-and-attitudes-toward-psychological-help-seeking-in-the-united-arab-emirates-the-mediational-role-of-self-stigma
#19
Zahir Vally, Brettjet L Cody, Maryam A Albloshi, Safeya N M Alsheraifi
PURPOSE: Scholars argue that public stigma is predictive of self-stigma, and self-stigma is a primary predictor of attitudes toward seeking psychological help (ATPH). This assertion remains undetermined outside of the United States. This study examines a potential mediational model in which internalized stigma was hypothesized to mediate the relationship between public stigma and ATPH using a sample in the United Arab Emirates. DESIGN AND METHODS: Cross-sectional, correlational design; 114 students completed measures of public stigma, self-stigma, and ATPH...
April 17, 2018: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/29666646/shisha-smoking-habit-among-dental-school-students-in-the-united-arab-emirates-enabling-factors-and-barriers
#20
Natheer H Al-Rawi, Ahmed S Alnuaimi, Asmaa T Uthman
Objectives: The objective of the present study was to assess shisha smoking among dental school students in Sharjah, United Arab Emirates (UAE). In addition, the role of suggested barriers and enabling factors in shisha smoking was also evaluated. Methods: A cross-sectional questionnaire-based survey was conducted at the College of Dental Medicine, University of Sharjah, between February and May 2016. The questions were adapted from previously published water pipe smoking studies...
2018: International Journal of Dentistry
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