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Roohollah Shirani Faradonbeh, Mahdi Hasanipanah, Hassan Bakhshandeh Amnieh, Danial Jahed Armaghani, Masoud Monjezi
Air overpressure (AOp) is one of the most adverse effects induced by blasting in the surface mines and civil projects. So, proper evaluation and estimation of the AOp is important for minimizing the environmental problems resulting from blasting. The main aim of this study is to estimate AOp produced by blasting operation in Miduk copper mine, Iran, developing two artificial intelligence models, i.e., genetic programming (GP) and gene expression programming (GEP). Then, the accuracy of the GP and GEP models has been compared to multiple linear regression (MLR) and three empirical models...
May 21, 2018: Environmental Monitoring and Assessment
Wen-Long Wang, Qian-Yuan Wu, Nan Huang, Zi-Bin Xu, Min-Yong Lee, Hong-Ying Hu
UV based advanced oxidation processes (UV-AOPs) that efficiently eliminate organic pollutants during water treatment have been the subject of numerous investigations. Most organic pollutants are not completely mineralized during UV-AOPs but are partially oxidized into transformation products (TPs), thereby adding complexity to the treated water and posing risks to humans, ecological systems, and the environment. While the degradation kinetics and mechanisms of pollutants have been widely documented, there is little information about the risks associated with TPs...
May 15, 2018: Water Research
Aleš Čelar, Ekrem Tafaj, Alexandra Graf, Stefan Lettner
OBJECTIVES: Malocclusions affect about two-thirds of the population and orthodontic treatment is justified in 65% of these. However, the associations between anterior and posterior occlusal plane (AOP, POP) inclinations and Angle classification are lacking. PATIENTS AND METHODS: In a retrospective study, lateral cephalometric radiograph tracings of 230 previously untreated Caucasians, aged 13 to 49 years, yielded inclines of the bisector occlusal plane, AOP, and POP...
May 17, 2018: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
Salatiel Wohlmuth da Silva, Alan Nelson Arenhart Heberle, Alexia Pereira Santos, Marco Antônio Siqueira Rodrigues, Valentín Pérez-Herranz, Andréa Moura Bernardes
Antibiotics are not efficiently removed in conventional wastewater treatments. In fact, different Advanced Oxidation Process (AOPs), including ozone, peroxide, UV radiation, among others, are being investigated in the elimination of microcontaminants. Most of AOPs proved to be efficient on the degradation of antibiotics, but the mineralization is on the one hand not evaluated or on the other hand not high. At this work, the UV-based hybrid process, namely Photo-assisted electrochemical Oxidation (PEO), was applied aiming the mineralization of microcontaminants such as the antibiotics Amoxicillin (AMX), Norfloxacin (NOR) and Azithromycin (AZI)...
May 17, 2018: Environmental Technology
Ximei Zhang, Feng Huang, Weixuan Li, Jun-Long Dang, Jia Yuan, Julie Wang, Dong-Lan Zeng, Can-Xing Sun, Yan-Ying Liu, Qian Ao, Hongmei Tan, Wenru Su, Xiaoxian Qian, Nancy Olsen, Song Guo Zheng
Atherosclerosis is the major cause of cardiovascular diseases. Current evidences indicate that inflammation is involved in the pathogenesis of atherosclerosis. Human gingiva-derived mesenchymal stem cells (GMSC) have shown anti-inflammatory and immunomodulatory effects on autoimmune and inflammatory diseases. However, the function of GMSC in controlling atherosclerosis is far from clear. The present study is aimed to elucidate the role of GMSC in atherosclerosis, examining the inhibition of GMSC on macrophage foam cell formation, and further determining whether GMSC could affect the polarization and activation of macrophages under different conditions...
2018: Frontiers in Immunology
Bahattin Tuncali, Hakan Boya, Zeynep Kayhan, Sukru Arac
OBJECTIVE: The aim of this study was to compare the limb occlusion pressure (LOP) determination and arterial occlusion pressure (AOP) estimation methods for tourniquet pressure setting in adult patients undergoing knee arthroplasty under combined spinal-epidural anesthesia. METHODS: Ninety-three patients were randomized into two groups. Pneumatic tourniquet inflation pressures were adjusted based either on LOP determination or AOP estimation in Group 1 (46 patients, 38 female and 8 male; mean age: 67...
May 8, 2018: Acta Orthopaedica et Traumatologica Turcica
Devagi Kanakaraju, Beverley D Glass, Michael Oelgemöller
Pharmaceuticals, which are frequently detected in natural and wastewater bodies as well as drinking water have attracted considerable attention, because they do not readily biodegrade and may persist and remain toxic. As a result, pharmaceutical residues pose on-going and potential health and environmental risks. To tackle these emerging contaminants, advanced oxidation processes (AOPs) such as photo-Fenton, sonolysis, electrochemical oxidation, radiation and ozonation etc. have been applied to remove pharmaceuticals...
May 7, 2018: Journal of Environmental Management
Shaodong Hou, Li Ling, Dionysios D Dionysiou, Yuru Wang, Jiajia Huang, Kaiheng Guo, Xuchun Li, Jingyun Fang
Halides and natural organic matter (NOM) are inevitable in aquatic environment and influence the degradation of contaminants in sulfate radical (SO4•‒)-based advanced oxidation processes. This study investigated the formation of chlorate in the co-exposure of SO4•‒, chloride (Cl‒), bromide (Br‒) and/or NOM in UV/persulfate (UV/PDS) and cobalt(II)/peroxymonosulfate (Co/PMS) systems. The formation of chlorate increased with increasing Cl‒ concentration in the UV/PDS system, however, in the Co/PMS system, it initially increased and then decreased...
May 10, 2018: Environmental Science & Technology
James J Foster, Shelby E Temple, Martin J How, Ilse M Daly, Camilla R Sharkey, David Wilby, Nicholas W Roberts
In "Polarisation vision: overcoming challenges of working with a property of light we barely see" (Foster et al. 2018) we provide a basic description of how Stokes parameters can be estimated and used to calculate the angle of polarisation (AoP).
May 3, 2018: Die Naturwissenschaften
Mylena Spina-Cruz, Milena Guedes Maniero, José Roberto Guimarães
Advanced oxidation processes (AOPs) have been highly efficient in degrading contaminants of emerging concern (CEC). This study investigated the efficiency of photolysis, peroxidation, photoperoxidation, and ozonation at different pH values to degrade doxycycline (DC) in three aqueous matrices: fountain, tap, and ultrapure water. More than 99.6% of DC degradation resulted from the UV/H2 O2 and ozonation processes. Also, to evaluate the toxicity of the original solution and throughout the degradation time, antimicrobial activity tests were conducted using Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) bacteria, and acute toxicity test using the bioluminescent marine bacterium (Vibrio fischeri)...
May 8, 2018: Environmental Science and Pollution Research International
Yu-Mei Tan, Jeremy A Leonard, Stephen Edwards, Justin Teeguarden, Alicia Paini, Peter Egeghy
Over time, risk assessment has shifted from establishing relationships between exposure to a single chemical and a resulting adverse health outcome, to evaluation of multiple chemicals and disease outcomes simultaneously. As a result, there is an increasing need to better understand the complex mechanisms that influence risk of chemical and non-chemical stressors, beginning at their source and ending at a biological endpoint relevant to human or ecosystem health risk assessment. Just as the Adverse Outcome Pathway (AOP) framework has emerged as a means of providing insight into mechanism-based toxicity, the exposure science community has seen the recent introduction of the Aggregate Exposure Pathway (AEP) framework...
June 2018: Current Opinion in Toxicology
Luke Hughes, Owen Jeffries, Mark Waldron, Ben Rosenblatt, Conor Gissane, Bruce Paton, Stephen D Patterson
Background: Total arterial occlusive pressure (AOP) is used to prescribe pressures for surgery, blood flow restriction exercise (BFRE) and ischemic preconditioning (IPC). AOP is often measured in a supine position; however, the influence of body position on AOP measurement is unknown and may influence level of occlusion in different positions during BFR and IPC. The aim of this study was therefore to investigate the influence of body position on AOP. Methods: Fifty healthy individuals (age = 29 ± 6 y) underwent AOP measurements on the dominant lower-limb in supine, seated and standing positions in a randomised order...
2018: PeerJ
Eduard Rott, Bertram Kuch, Claudia Lange, Philipp Richter, Amélie Kugele, Ralf Minke
Effluent of a municipal wastewater treatment plant (WWTP) was treated on-site with the UV/chlorine (UV/HOCl) advanced oxidation process (AOP) using a pilot plant equipped with a medium pressure UV lamp with an adjustable performance of up to 1 kW. Results obtained from parallel experiments with the same pilot plant, where the state of the art UV/H₂O₂ AOP was applied, were compared regarding the removal of emerging contaminants (EC) and the formation of adsorbable organohalogens (AOX). Furthermore, the total estrogenic activity was measured in samples treated with the UV/chlorine AOP...
May 7, 2018: International Journal of Environmental Research and Public Health
J Rodríguez-Chueca, C García-Cañibano, R-J Lepistö, Á Encinas, J Pellinen, J Marugán
This study explores the enhancement of UV-C tertiary treatment by sulfate radical based Advanced Oxidation Processes (SR-AOPs), including photolytic activation of peroxymonosulfate (PMS) and persulfate (PS) and their photocatalytic activation using Fe(II). Their efficiency was assessed both for the inactivation of microorganisms and the removal or micropollutants (MPs) in real wastewater treatment plant effluents. Under the studied experimental range (UV-C dose 5.7-57 J/L; UV-C contact time 3 to 28 s), the photolysis of PMS and PS (0...
April 21, 2018: Journal of Hazardous Materials
Sarek A Shen, Aria Jafari, David Bracken, John Pang, Adam S DeConde
BACKGROUND: Endoscopic sinus surgery (ESS) is generally well tolerated, yet a subset of patients require an additional opiate prescription in the postoperative period. The purpose of this study was to quantify differences in both preoperative and immediate postoperative 22-item Sino-Nasal Outcome Test (SNOT-22) scores between patients with a single prescription and those requiring additional opiate prescriptions (AOPs). METHODS: Patients undergoing ESS between November 2016 and August 2017 were reviewed retrospectively...
May 3, 2018: International Forum of Allergy & Rhinology
Pengpeng Qiu, Beomguk Park, Jongbok Choi, Binota Thokchom, Aniruddha B Pandit, Jeehyeong Khim
Heterogeneous sonocatalysis, as an emerging advanced oxidation process (AOP), has shown immense potential in water treatment and been widely demonstrated to remove persistent organic compounds in the past decade. The present article aims to provide a comprehensive review on the development of a heterogeneous catalyst for enhancing the ultrasonic degradation rate of organic pollutants from a viewpoint of sonocatalytic mechanism. The rational design and fundamentals for preparing sonocatalysts are presented in the context of facilitating the heterogeneous nucleation and photo-thermal-catalytic effects as well as considering the mechanical stability and separation capacity of the heterogeneous catalyst...
July 2018: Ultrasonics Sonochemistry
Michał Gągol, Andrzej Przyjazny, Grzegorz Boczkaj
Cavitation has become on the most often applied methods in a number of industrial technologies. In the case of oxidation of organic pollutants occurring in the aqueous medium, cavitation forms the basis of numerous advanced oxidation processes (AOPs). This paper presents the results of investigations on the efficiency of oxidation of the following groups of organic compounds: organosulfur, nitro derivatives of benzene, BTEX, and phenol and its derivatives in a basic model effluent using hydrodynamic and acoustic cavitation combined with external oxidants, i...
July 2018: Ultrasonics Sonochemistry
Evelyn Stinckens, Lucia Vergauwen, Gerald T Ankley, Ronny Blust, Veerle M Darras, Daniel L Villeneuve, Hilda Witters, David C Volz, Dries Knapen
The adverse outcome pathway (AOP) framework can be used to help support the development of alternative testing strategies aimed at predicting adverse outcomes caused by triggering specific toxicity pathways. In this paper, we present a case-study demonstrating the selection of alternative in chemico assays targeting the molecular initiating events of established AOPs, and evaluate use of the resulting data to predict higher level biological endpoints. Based on two AOPs linking inhibition of the deiodinase (DIO) enzymes to impaired posterior swim bladder inflation in fish, we used in chemico enzyme inhibition assays to measure the molecular initiating events for an array of 51 chemicals...
April 21, 2018: Aquatic Toxicology
Deborah M Proctor, Mina Suh, Grace Chappell, Susan J Borghoff, Chad M Thompson, Karin Wiench, Lavorgie Finch, Robert Ellis-Hutchings
The utility of rodent forestomach tumor data for hazard and risk assessment has been examined for decades because humans do not have a forestomach, and these tumors occur by varying modes of action (MOAs). We have used the MOA for ethyl acrylate (EA) to develop an Adverse Outcome Pathway (AOP) for forestomach tumors caused by non-genotoxic initiating events. These tumors occur secondary to site of contact induced epithelial cytotoxicity and regenerative repair-driven proliferation. For EA, the critical initiating event (IE) is epithelial cytotoxicity, and supporting key events (KEs) at the cellular and tissue level are increased cell proliferation (KE1) resulting in sustained hyperplasia (KE2), with the adverse outcome of forestomach papillomas and carcinomas...
April 20, 2018: Regulatory Toxicology and Pharmacology: RTP
Gerald T Ankley, Stephen W Edwards
The adverse outcome pathway (AOP) framework serves as a knowledge assembly, interpretation, and communication tool designed to support the translation of pathway-specific mechanistic data into responses relevant to assessing and managing risks of chemicals to human health and the environment. As such, AOPs facilitate the use of data streams often not employed by risk assessors, including information from in silico models, in vitro assays and short-term in vivo tests with molecular/biochemical endpoints. This translational capability can increase the capacity and efficiency of safety assessments both for single chemicals and chemical mixtures...
June 1, 2018: Current Opinion in Toxicology
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