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https://www.readbyqxmd.com/read/29240176/highly-efficient-optical-parametric-amplifier-tunable-from-near-to-mid-ir-for-driving-extreme-nonlinear-optics-in-solids
#1
E A Migal, F V Potemkin, V M Gordienko
We have developed a robust optical parametric amplifier (OPA) based on three-AgGaS2-crystal pumping by a Cr:Forsterite GW femtosecond laser system, generating 150 fs pulses in dual bands of 1.6-2.0 μm (signal wave) and 3.5-5.5 μm (idler wave). By introducing a negative prechirp to the pump, a combined efficiency in two waves of greater than 10% was achieved, with signal energy up to 110 μJ and idler energy up to 43 μJ. Operation parameters of the system (intensity up to 90  TW/cm2) make OPA a promising tool for driving nonlinear optical phenomena, including generation of optical harmonics and laser-induced extreme states of matter in solids and liquids...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29239582/health-promotion-among-the-population-of-foreign-origin-in-finland-involves-special-issues
#2
Anu E Castaneda, Hannamaria Kuusio, Natalia Skogberg, Karolina Tuomisto, Sinikka Kytö, Emmi Salmivuori, Satu Jokela, Johanna Mäki-Opas, Tiina Laatikainen, Päivikki Koponen
The population of foreign origin in Finland is a heterogenic group, diverse for example with respect to reasons for and age at migration. While migration to Finland is a recent phenomenon, the size of the population of foreign origin has grown rapidly and will continue to increase. Changes in the population structure need to be taken into account in health promotion. For example lifestyle, health status, functional capacity, mental health, infectious diseases and reproductive health differ in foreign origin population compared with the general Finnish population...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29226666/fluorogenic-detection-of-monoamine-neurotransmitters-in-live-cells
#3
Kallol Bera, Anand Kant Das, Ananya Rakshit, Bidyut Sarkar, Anoop Rawat, Barun Kumar Maity, Sudipta Maiti
Monoamine neurotransmission is key to neuromodulation, but imaging monoamines in live neurons has remained a challenge. Here we show that externally added ortho-phthalaldehyde (OPA) can permeate live cells and form bright fluorogenic adducts with intracellular monoamines (e.g. setrotonin, dopamine and nor-epinephrine) and with L-DOPA, which can be imaged sensitively using conventional single-photon excitation in a fluorescence microscope. The peak excitation and emission wavelengths (λex = 401 nm and λem = 490 nm for serotonin; λex = 446 nm and λem = 557 nm for dopamine; and λex = 446 nm and λem = 544 nm for nor-epinephrine) are accessible to most modern confocal imaging instruments...
December 11, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29225719/methane-optical-density-measurements-with-an-integrated-path-differential-absorption-lidar-from-an-airborne-platform
#4
Haris Riris, Kenji Numata, Stewart Wu, Brayler Gonzalez, Michael Rodriguez, Stan Scott, Stephan Kawa, Jianping Mao
We report on an airborne demonstration of atmospheric methane (CH4) measurements with an Integrated Path Differential Absorption (IPDA) lidar using an optical parametric amplifier (OPA) and optical parametric oscillator (OPO) laser transmitter and sensitive avalanche photodiode detector. The lidar measures the atmospheric CH4 absorption at multiple, discrete wavelengths near 1650.96 nm. The instrument was deployed in the fall of 2015, aboard NASA's DC-8 airborne laboratory along with an in-situ spectrometer and measured CH4 over a wide range of surfaces and atmospheric conditions from altitudes of 2 km to 13 km...
July 2017: Journal of Applied Remote Sensing
https://www.readbyqxmd.com/read/29215305/cerebrovascular-function-and-mitochondrial-bioenergetics-after-ischemia-reperfusion-in-male-rats
#5
Ibolya Rutkai, Ivan Merdzo, Sanjay V Wunnava, Genevieve T Curtin, Prasad Vg Katakam, David W Busija
The underlying factors promoting increased mitochondrial proteins, mtDNA, and dilation to mitochondrial-specific agents in male rats following tMCAO are not fully elucidated. Our goal was to determine the morphological and functional effects of ischemia/reperfusion (I/R) on mitochondria using electron microscopy, Western blot, mitochondrial oxygen consumption rate (OCR), and Ca2+ sparks activity measurements in middle cerebral arteries (MCAs) from male Sprague Dawley rats (Naïve, tMCAO, Sham). We found a greatly increased OCR in ipsilateral MCAs (IPSI) compared with contralateral (CONTRA), Sham, and Naïve MCAs...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29214017/morphological-bactericidal-fast-acting-effects-of-peracetic-acid-a-high-level-disinfectant-against-staphylococcus-aureus-and-pseudomonas-aeruginosa-biofilms-in-tubing
#6
T Chino, Y Nukui, Y Morishita, K Moriya
Background: The bactericidal effect of disinfectants against biofilms is essential to reduce potential endoscopy-related infections caused by contamination. Here, we investigated the bactericidal effect of a high-level disinfectant, peracetic acid (PAA), against Staphylococcus aureus and Pseudomonas aeruginosa biofilm models in vitro. Methods: S. aureus and P. aeruginosa biofilms were cultured at 35 °C for 7 days with catheter tubes. The following high-level disinfectants (HLDs) were tested: 0...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29209783/acute-effect-on-ambulatory-blood-pressure-from-aerobic-exercise-a-randomised-cross-over-study-among-female-cleaners
#7
Charlotte Lund Rasmussen, Line Nielsen, Marie Linander Henriksen, Karen Søgaard, Peter Krustrup, Andreas Holtermann, Mette Korshøj
PURPOSE: High occupational physical activity (OPA) is shown to increase the risk for elevated blood pressure, cardiovascular diseases and mortality. Conversely, aerobic exercise acutely lowers the blood pressure up to 25 h post exercise. However, it is unknown if this beneficial effect also apply for workers exposed to high levels of OPA. Cleaners constitute a relevant occupational group for this investigation because of a high prevalence of OPA and cardiovascular disease. Accordingly, the objective was to investigate the acute effects on ambulatory blood pressure from a single aerobic exercise session among female cleaners...
December 5, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29202298/impact-of-ph-and-application-time-of-meta-phosphoric-acid-on-resin-enamel-and-resin-dentin-bonding
#8
A F M Cardenas, F S F Siqueira, M C Bandeca, S O Costa, M V S Lemos, V P Feitora, A Reis, A D Loguercio, J C Gomes
PURPOSE: To evaluate the immediate microshear resin-enamel bond strength (μSBS) and the immediate and 6-month microtensile bond strength (μTBS) and nanoleakage (NL) of the adhesive interface performed by different pHs of 40% meta-phosphoric acid (MPA) were compared with conventional 37% ortho-phosphoric acid (OPA) under different application times. Additionally, the enamel etching patterns were evaluated and the chemical/morphological changes induced by these differents groups were evaluated...
November 22, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29159320/immunogenicity-and-persistence-of-the-13-valent-pneumococcal-conjugate-vaccine-pcv13-in-patients-with-untreated-smoldering-multiple-myeloma-smm-a-pilot-study
#9
Mathilde Bahuaud, Hélène Bodilis, Marion Malphettes, Anaïs Maugard Landre, Caroline Matondo, Didier Bouscary, Frédéric Batteux, Odile Launay, Jean-Paul Fermand
Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder that frequently progress to multiple myeloma (MM), a disease at high risk of pneumococcal infections. Moreover, if the polysaccharide vaccine is poorly immunogenic in MM, the 13-valent conjugated vaccine has never been tested in clonal plasma cell disorders. We evaluated its immunogenicity for 7 serotypes in 20 patients ≥ 50 years of age with smoldering multiple myeloma (SMM) pre and post routine-vaccination with PCV13. Concentrations of IgG specific for 7 serotypes were measured at baseline, 1, 6, and 12 months after vaccination by standardized ELISA and an Opsonophagocytic Assay (OPA)...
November 2017: Heliyon
https://www.readbyqxmd.com/read/29145138/exposure-to-selected-limonene-oxidation-products-4-opa-ipoh-4-amch-induces-oxidative-stress-and-inflammation-in-human-lung-epithelial-cell-lines
#10
Dorelia Lipsa, Josefa Barrero-Moreno, Mehmet Coelhan
Limonene oxidation products (LOPs) have gained interest on their harmful health effects over time. Recently, studies have shown that the selected LOPs: 4-oxopentanal (4-OPA), 3-isopropenyl-6-oxo-heptanal (IPOH) and 4-acetyl-1-methylcyclohexene (4-AMCH) have sensory irritation effects in mice and inflammatory effects in human lung cells. This study was therefore undertaken to investigate the potential capacity of 4-OPA, IPOH and 4-AMCH to cause cell membrane damage, oxidative stress and inflammation in human bronchial (16HBE14o-) and alveolar (A549) epithelial cell lines...
October 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/29142388/analysis-of-free-amino-acids-in-different-extracts-of-orthosiphon-stamineus-leaves-by-high-performance-liquid-chromatography-combined-with-solid-phase-extraction
#11
Armaghan Shafaei, Nor Hidayah Ab Halim, Norhidayah Zakaria, Zhari Ismail
Background: Orthosiphon stamineus (OS) Benth is a medicinal plant and native in Southeast Asia. Previous studies have shown that OS leaves possess antioxidant, cytotoxic, diuretic, antihypertensive, and uricosuric effects. These beneficial effects have been attributed to the presence of primary and secondary metabolites such as polyphenols, amino acids, and flavonoids. Objective: To develop and validate an high-performance liquid chromatography (HPLC)-diode array detector (DAD) method combined with solid-phase extraction that involves precolumn derivatization with O-phthaladehyde for simultaneous analysis of free amino acids in OS leaves extracts...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29111013/genotype-phenotype-and-oct-correlations-in-autosomal-dominant-optic-atrophy-related-to-opa1-gene-mutations-report-of-13-italian-families
#12
E Pretegiani, F Rosini, A Rufa, G N Gallus, E Cardaioli, P Da Pozzo, S Bianchi, V Serchi, M Collura, R Franceschini, S Bianchi Marzoli, M T Dotti, A Federico
Mutations in OPA1 are responsible of 32-89% cases of Autosomal Dominant Optic Atrophy (ADOA). OPA1 ADOA usually presents in childhood with bilateral, progressive visual loss due to retinal ganglion cells neurodegeneration, but environmental factors are supposed to influence onset and phenotype. Sixty Italian OPA1 mutations carriers (fifty-two symptomatic), belonging to thirteen families, underwent neuro-ophthalmologic evaluation. Visual acuity (n=60) and Optical Coherence Tomography (OCT) (n=12) were compared in missense mutations (OPA-M) versus haploinsufficiency-inducing mutations (OPA-H) and correlated with age...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29110107/effect-of-light-conditions-and-chemical-characteristics-of-water-on-dissipation-of-glyphosate-in-aqueous-medium
#13
Veena Yadav, Pervinder Kaur, Paawan Kaur
The present study was conducted to determine the effect of light conditions and chemical properties of water on dissipation of glyphosate. The residues of glyphosate and aminomethylphosphonic acid (AMPA) were quantified using fluorescence spectrophotometer after derivatization with 9-fluoroenylmethoxycarbonyl chloride (FMOC-Cl) and orthopthaldehyde (OPA). Average percent recoveries of glyphosate and AMPA from distilled, tap, and ground water ranged from 87.5 to 94.9, 87.3 to 93.7, and 80.6 to 92.0, respectively, with relative standard deviation less than 10%...
November 6, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29104631/ocular-pulse-amplitude-in-different-types-of-glaucoma-using-dynamic-contour-tonometry-diagnosis-and-follow-up-of-glaucoma
#14
Lingyan Cheng, Yuzhi Ding, Xuanchu Duan, Zhifeng Wu
The aim of the present study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma using dynamic contour tonometry (DCT), to evaluate ocular and systemic factors associated with the OPA and to verify whether OPA measured by DCT is an independent predictor for glaucoma diagnosis. A total of 217 eyes of 217 participants in the following five groups were included in this cross-sectional study: Chronic angle closure glaucoma (CACG), primary open angle glaucoma, normal tension glaucoma (NTG), suspected open angle glaucoma (SOAG) and normal control (NC)...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29101713/muscle-relaxants-as-a-risk-factor-for-vis-%C3%A3-tergo-during-penetrating-keratoplasty-a-prospective-interventional-study
#15
Miltiadis Fiorentzis, Emanuela Morinello, Anja Viestenz, Hanna Zuche, Berthold Seitz, Arne Viestenz
INTRODUCTION: This study aimed to investigate the influence of three muscle relaxants on intraocular pressure (IOP), ocular pulse amplitude (OPA), and vis-à-tergo (VAT) in patients undergoing penetrating keratoplasty (PKP) under general anesthesia. METHODS: Ninety-five patients undergoing PKP were included in this prospective single-center interventional study. IOP and OPA were measured with a dynamic contour tonometer before and 5 min after onset of general anesthesia...
November 3, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29099122/the-intrinsic-basicity-of-the-phosphate-backbone-exceeds-that-of-uracil-and-thymine-residues-protonation-of-the-phosphate-moiety-is-preferred-over-the-nucleobase-for-pdthd-and-purd
#16
R R Wu, L A Hamlow, C C He, Y-W Nei, G Berden, J Oomens, M T Rodgers
The gas-phase conformations of the protonated forms of thymidine-5'-monophosphate and uridine-5'-monophosphate, [pdThd+H](+) and [pUrd+H](+), are investigated by infrared multiple photon dissociation (IRMPD) action spectroscopy and electronic structure calculations. The IRMPD action spectra of [pdThd+H](+) and [pUrd+H](+) are measured over the IR fingerprint and hydrogen-stretching regions using the FELIX free electron laser and an OPO/OPA laser system. Low-energy conformations of [pdThd+H](+) and [pUrd+H](+) and their relative stabilities are computed at the MP2(full)/6-311+G(2d,2p)//B3LYP/6-311+G(d,p) and B3LYP/6-311+G(2d,2p)//B3LYP/6-311+G(d,p) levels of theory...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29094169/objectively-measured-occupational-and-leisure-time-physical-activity-cross-sectional-associations-with-sleep-problems
#17
Eivind Schjelderup Skarpsno, Paul Jarle Mork, Tom Ivar Lund Nilsen, Marie Birk Jørgensen, Andreas Holtermann
Objectives This study aimed to investigate (i) the associations between occupational physical activity (OPA) and leisure-time physical activity (LTPA) with insomnia symptoms and non-restorative sleep and (ii) the joint associations between OPA and LTPA with insomnia symptoms and non-restorative sleep, respectively. Methods Data were drawn from a cross-sectional study including 650 workers in the Danish PHysical ACTivity cohort with Objective measurements (DPhacto). OPA and LTPA were measured with accelerometers on the thigh and upper back for up to six consecutive days and subsequently divided into quartiles of "very low", "low", "medium" and "high" activity...
November 2, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29093787/significance-of-stabilometry-for-assessing-postoperative-body-sway-in-patients-with-cervical-myelopathy
#18
Shinji Tanishima, Hideki Nagashima, Hiroyuki Ishii, Satoru Fukata, Toshiyuki Dokai, Taiki Murakami, Yasuo Morio
Study Design: Prospective study. Purpose: To examine the changes in body sway using stabilometry in patients who underwent cervical laminoplasty for cervical myelopathy. Overview of Literature: Although the patients of cervical myelopathy complain body sway there are few report to examine body sway objectively. Methods: Patients who received treatment for cervical myelopathy between October 2010 and February 2013 were included...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29082342/euclidean-genetic-distances-of-four-manila-clam-ruditapes-philippinarum-populations-analyzed-by-pcr-research
#19
Jong-Man Yoon
The PCR analysis was performed on DNA samples extracted from a total of 20 individuals using six oligonucleotides primers. The author accomplished clustering analyses to reveal the Euclidean genetic distances among four clam populations from Gochang, Seocheon, Taean and Anmyeon of the Korean peninsula. The oligonucleotides primer OPA-08 generated 5 unique loci to each population, approximately 550 bp and 600 bp, respectively, in the MCS population. Especially, the primer OPA-20 generated 15 unique loci to each population, which were identifying each population, approximately 400 bp, 750 bp and 800 bp, in the MCT population...
September 2017: Balsaeng'gwa Saengsig
https://www.readbyqxmd.com/read/29080224/safety-tolerability-and-pharmacokinetics-of-l-ornithine-phenylacetate-in-patients-with-acute-liver-injury-failure-and-hyperammonemia
#20
R Todd Stravitz, Michelle Gottfried, Valerie Durkalski, Robert J Fontana, A James Hanje, David Koch, Bilal Hameed, Daniel Ganger, Ram M Subramanian, Stan Bukofzer, William R Ravis, Kristen Clasen, Averell Sherker, Lanna Little, William M Lee
Cerebral edema remains a significant cause of morbidity and mortality in patients with acute liver failure (ALF) and has been linked to elevated blood ammonia levels. L-ornithine phenylacetate (OPA) may decrease ammonia by promoting its renal excretion as phenylacetylglutamine (PAGN), decreasing the risk of cerebral edema. We evaluated the safety, tolerability, and pharmacokinetics of OPA in patients with ALF and acute liver injury (ALI), including those with renal failure. Forty-seven patients with ALI/ALF and ammonia ≥60µM were enrolled...
October 28, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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