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https://www.readbyqxmd.com/read/28822863/an-x-ray-absorption-fine-structure-spectroscopy-study-of-metal-sorption-to-graphene-oxide
#1
Allison R Showalter, Thomas A Duster, Jennifer E S Szymanowski, Chongzheng Na, Jeremy B Fein, Bruce A Bunker
Remediation and prevention of environmental contamination by toxic metals is an ongoing issue. Additionally, improving water filtration systems is necessary to prevent toxic metals from circulating through the water supply. Graphene oxide (GO) is a highly sorptive material for a variety of heavy metals under different ionic strength conditions over a wide pH range, making it a promising candidate for use in metal adsorption from contaminated sites or in filtration systems. We present X-ray absorption fine structure (XAFS) spectroscopy results investigating the binding environment of Cd (II), U(VI) and Pb(II) ions onto multi-layered graphene oxide (MLGO)...
August 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28822830/chronic-kidney-disease-in-long-term-survivors-after-allogeneic-hematopoietic-stem-cell-transplantation-retrospective-analysis-at-a-single-institute
#2
Tomoyasu Jo, Yasuyuki Arai, Tadakazu Kondo, Toshiyuki Kitano, Masakatsu Hishizawa, Kouhei Yamashita, Akifumi Takaori-Kondo
The number of patients eligible for allogeneic stem cell transplantation (allo-HSCT) has increased because of improvements in transplantation procedures. Among long-term survivors of allo-HSCT, chronic kidney disease (CKD) is a major cause of morbidity. We retrospectively analyzed the clinical data of 106 consecutive patients with a median age of 43 (17-73) years who had undergone allo-HSCT at our institution between January 2001 and September 2009. Patients who died within 5 years after transplantation or had CKD at the time of transplantation were excluded in this study...
August 16, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28822586/intravenous-mannitol-versus-placebo-during-partial-nephrectomy-in-patients-with-normal-kidney-function-a-double-blind-clinically-integrated-randomized-trial
#3
Massimiliano Spaliviero, Nicholas E Power, Katie S Murray, Daniel D Sjoberg, Nicole E Benfante, Melanie L Bernstein, James Wren, Paul Russo, Jonathan A Coleman
BACKGROUND: Mannitol is currently used as a renal protective agent to mitigate the effects of renal ischemia during nephron-sparing surgery (NSS). This routine practice lacks rigorous methodological study. OBJECTIVE: To assess the effect on renal function outcomes after surgery of mannitol infusion prior to renal ischemia during NSS. DESIGN, SETTING, PARTICIPANTS: This prospective, randomized, placebo-controlled, double-blind trial included 199 patients with a preoperative estimated glomerular filtration rate (eGFR) >45ml/min/1...
August 16, 2017: European Urology
https://www.readbyqxmd.com/read/28822537/impaired-renal-function-should-not-be-a-barrier-to-transplantation-in-patients-with-cystic-fibrosis
#4
Todd C Crawford, J Trent Magruder, Joshua C Grimm, Alejandro Suarez-Pierre, Xun Zhou, Jinny S Ha, Robert S Higgins, Stephen R Broderick, Jonathan B Orens, Pali Shah, Christian A Merlo, Bo S Kim, Errol L Bush
BACKGROUND: Previous studies have demonstrated an association between pretransplantation renal dysfunction (PRD) and increased mortality after lung transplantation (LT). The purpose of this study was to determine whether PRD impacts survival after LT in patients with cystic fibrosis (CF). METHODS: We queried the United Network for Organ Sharing (UNOS) database to identify all adult (≥18 years) recipients with CF who underwent isolated LT from May 4, 2005 to December 31, 2014...
August 16, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28822343/the-control-of-disinfection-byproducts-and-their-precursors-in-biologically-active-filtration-processes
#5
REVIEW
Chao Liu, Christopher I Olivares, Ameet J Pinto, Chance V Lauderdale, Jess Brown, Meric Selbes, Tanju Karanfil
While disinfection provides hygienically safe drinking water, the disinfectants react with inorganic or organic precursors, leading to the formation of harmful disinfection byproducts (DBPs). Biological filtration is a process in which an otherwise conventional granular filter is designed to remove not only fine particulates but also dissolved organic matters (e.g., DBP precursors) through microbially mediated degradation. Recently, applications of biofiltration in drinking water treatment have increased significantly...
August 4, 2017: Water Research
https://www.readbyqxmd.com/read/28822048/evaluation-of-methods-to-determine-adsorption-of-polycyclic-aromatic-hydrocarbons-to-dispersed-carbon-nanotubes
#6
Berit Glomstad, Lisbet Sørensen, Jingfu Liu, Mohai Shen, Florian Zindler, Bjørn M Jenssen, Andy M Booth
A number of methods have been reported for determining hydrophobic organic compound adsorption to dispersed carbon nanotubes (CNTs), but their accuracy and reliability remain uncertain. We have evaluated three methods to investigate the adsorption of phenanthrene (a model polycyclic aromatic hydrocarbon, PAH) to CNTs with different physicochemical properties: dialysis tube (DT) protected negligible depletion solid phase microextraction (DT-nd-SPME), ultracentrifugation, and filtration using various types of filters...
August 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28821713/evaluating-the-causal-relation-of-apoa-iv-with-disease-related-traits-a-bidirectional-two-sample-mendelian-randomization-study
#7
Salome Mack, Stefan Coassin, Julien Vaucher, Florian Kronenberg, Claudia Lamina
Apolipoprotein A-IV (apoA-IV) has been observed to be associated with lipids, kidney function, adiposity- and diabetes-related parameters. To assess the causal relationship of apoA-IV with these phenotypes, we conducted bidirectional Mendelian randomization (MR) analyses using publicly available summary-level datasets from GWAS consortia on apoA-IV concentrations (n = 13,813), kidney function (estimated glomerular filtration rate (eGFR), n = 133,413), lipid traits (HDL cholesterol, LDL cholesterol, triglycerides, n = 188,577), adiposity-related traits (body-mass-index (n = 322,206), waist-hip-ratio (n = 210,088)) and fasting glucose (n = 133,010)...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821595/a-computational-model-of-1-5-ag-dynamics-during-pregnancy
#8
Seyedeh M Zekavat, Slava Butkovich, Grace J Young, David M Nathan, Danny Petrasek
The importance of 1,5-anhydroglucitol (1,5-AG) as an intermediate biomarker for diabetic pregnancy is multi-fold: (1) it serves as a reliable indicator of moderate-level glycemic control, especially during early gestation; (2) it has been associated with increased risk of diabetes, independent of HbA1c and fasting glucose; and (3) it is an independent risk factor for the development of eclampsia during pregnancy. However, the clinical use of this biomarker during pregnancy has been underutilized due to physiological changes in glomerular filtration rate, plasma volume, and other hemodynamic parameters which have been hypothesized to bias gestational serum 1,5-AG concentrations...
August 2017: Physiological Reports
https://www.readbyqxmd.com/read/28821307/determination-of-residues-of-diazinon-and-chlorpyrifos-in-lavender-and-rosemary-leaves-by-gas-chromatography
#9
Mamdouh R Rezk, Abd El-Aziz B Abd El-Aleem, Shaban M Khalile, Omneya K El-Naggar
A sensitive gas chromatographic (GC) GC method has been developed for the determination of diazinon and chlorpyrifos residues in lavender and rosemary leaves. The developed method consists of blending weighed samples of chopped leaves with sodium sulfate as the dehydrating agent, extraction with ethyl acetate, filtration, evaporation with a rotary evaporator, and, finally, capillary GC determination of the pesticides. The recoveries of the method were greater than 90%, and the LOQ was less than 0.1 µg/mL...
August 18, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28821094/decoration-of-open-pore-network-in-polyvinylidene-fluoride-mwcnts-with-chitosan-for-the-removal-of-reactive-orange-16-dye
#10
Maria Wasim, Sadia Sagar, Aneela Sabir, Muhammad Shafiq, Tahir Jamil
Inspired by the hydrophilic, biocompatible, adsorbent properties of chitosan. A simple, adaptable, green synthesis method was developed to prepare a thin film composite membranes using chitosan as a pore decorating material for the removal of anionic dye-Reactive orange 16 (RO-16). The hydrophilic chitosan was used to fill up the porous hydrophobic PVDF substrate, modified by MWCNTs. The dye rejection was carried out through the formation of a strong electrostatic interaction between the cationic group of chitosan surface and the anionic group of RO-16 dye...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821058/exploration-of-permeability-and-antifouling-performance-on-modified-cellulose-acetate-ultrafiltration-membrane-with-cellulose-nanocrystals
#11
Jinling Lv, Guoquan Zhang, Hanmin Zhang, Fenglin Yang
Cellulose nanocrystals (CNCs) were introduced into cellulose diacetate (CDA) matrix via immerged phase-inversion process, aiming to improve the filtration and antifouling performance of CNCs/CDA blending membrane. The effects of CNCs on membrane morphologies, hydrophilicity, permeability and antifouling property were investigated. Results showed that the incorporation of CNCs into CDA membrane could effectively enhance the permeability and antifouling property of CNCs/CDA blending membrane by optimizing membrane microstructure and improving membrane hydrophilicity...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820993/changing-profiles-of-bound-water-content-and-distribution-in-the-activated-sludge-treatment-by-nacl-addition-and-ph-modification
#12
Dong-Qin He, Ying-Jie Zhang, Chuan-Shu He, Han-Qing Yu
Currently the dewatering of activated sludge from wastewater treatment plants is a problem not well solved. Extracellular polymeric substances (EPS), including loosely bound EPS (LB-EPS) and tightly bound EPS (TB-EPS), are highly hydrated biopolymers and play important roles in sludge dewatering. In the present work, two types of treatments, i.e., salt addition and pH modification, were proposed to evaluate the effects of bound water content and its distribution on the dewatering performance of activated sludge...
August 10, 2017: Chemosphere
https://www.readbyqxmd.com/read/28819846/filter-adapted-fluorescent-in-situ-hybridization-fa-fish-for-filtration-enriched-circulating-tumor-cells
#13
Marianne Oulhen, Emma Pailler, Vincent Faugeroux, Françoise Farace
Circulating tumor cells (CTCs) may represent an easily accessible source of tumor material to assess genetic aberrations such as gene-rearrangements or gene-amplifications and screen cancer patients eligible for targeted therapies. As the number of CTCs is a critical parameter to identify such biomarkers, we developed fluorescent in situ hybridization (FISH) for CTCs enriched on filters (filter-adapted-FISH, FA-FISH). Here, we describe the FA-FISH protocol, the combination of immunofluorescent staining (DAPI/CD45) and FA-FISH techniques, as well as the semi-automated microscopy method that we developed to improve the feasibility and reliability of FISH analyses in filtration-enriched CTC...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28819845/automated-microfluidic-filtration-and-immunocytochemistry-detection-system-for-capture-and-enumeration-of-circulating-tumor-cells-and-other-rare-cell-populations-in-blood
#14
Michael Pugia, Mark Jesus M Magbanua, John W Park
Isolation by size using a filter membrane offers an antigen-independent method for capturing rare cells present in blood of cancer patients. Multiple cell types, including circulating tumor cells (CTCs), captured on the filter membrane can be simultaneously identified via immunocytochemistry (ICC) analysis of specific cellular biomarkers. Here, we describe an automated microfluidic filtration method combined with a liquid handling system for sequential ICC assays to detect and enumerate non-hematologic rare cells in blood...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28819844/fourier-ptychographic-microscopy-for-rapid-high-resolution-imaging-of-circulating-tumor-cells-enriched-by-microfiltration
#15
Anthony Williams, Jaebum Chung, Changhuei Yang, Richard J Cote
Examining the hematogenous compartment for evidence of metastasis has increased significantly within the oncology research community in recent years, due to the development of technologies aimed at the enrichment of circulating tumor cells (CTCs), the subpopulation of primary tumor cells that gain access to the circulatory system and are responsible for colonization at distant sites. In contrast to other technologies, filtration-based CTC enrichment, which exploits differences in size between larger tumor cells and surrounding smaller, non-tumor blood cells, has the potential to improve CTC characterization through isolation of tumor cell populations with greater molecular heterogeneity...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28819843/microfilter-based-capture-and-release-of-viable-circulating-tumor-cells
#16
Siddarth Rawal, Zheng Ao, Ram H Datar, Ashutosh Agarwal
Microfilters with slot-pore geometry can be used for size-based capture of circulating tumor cells (CTC) from the blood of cancer patients. The slot pore geometry reduces the shear stress that the cells would typically experience during filtration process and allows the cells to remain viable. The microfilter provides a platform capable of high CTC capture efficiency; however, the release of these cells from the filter following capture is nontrivial, possibly due to the strong nonspecific electrostatic adhesion of CTC to the microfilter surface...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28819835/efficacy-and-safety-of-linagliptin-in-2681-asian-patients-stratified-by-age-obesity-and-renal-function-a-pooled-analysis-of-randomized-clinical-trials
#17
Guang Ning, Tushar Bandgar, Uwe Hehnke, Jisoo Lee, Juliana C N Chan
INTRODUCTION: Asian patients with type 2 diabetes (T2D) are younger, leaner, and more likely to develop renal dysfunction than White populations. In this multiethnic analysis of data from phase 3 trials, we investigated the efficacy and safety of the dipeptidyl peptidase-4 inhibitor linagliptin in Asians stratified by these subphenotypes. METHODS: Data from randomized, double-blind, placebo-controlled trials evaluating linagliptin (as monotherapy, add-on therapy to metformin ± sulfonylurea, combined with pioglitazone or added to insulin) were pooled with efficacy data from 11 randomized trials of at least 24 weeks and safety data from 15 trials of various durations...
August 17, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28819739/oligosaccharide-elicitor-prepared-from-salecan-triggers-the-defense-responses-of-arabidopsis-thaliana-col0-against-botrytis-cinerea-infection
#18
Haiyang Xu, Jing Li, Shiming Wang, Linxiang Xu, Rui Cheng, Jianfa Zhang
Oligosaccharides from the water-soluble β-glucan, Salecan, were investigated to evaluate the activation effect on the defense responses of Arabidopsis thaliana Col0. Salecan oligosaccharides (ScOs, DP 5-10) were prepared at first by acid hydrolysis and gel filtration chromatography and then employed for foliar spray on Arabidopsis seedlings and plants. After ScOs treatment, increase of hydrogen peroxide was histologically and analytically detected in leaves. Transcription levels of several indicator genes which correspond to the signaling pathways and pathogenesis-related proteins were up-regulated at different time by means of quantitative RT-PCR analysis...
August 17, 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28819681/low-level-environmental-cadmium-exposure-induces-kidney-tubule-damage-in-the-general-population-of-korean-adults
#19
Sang-Yong Eom, Mi-Na Seo, Young-Sub Lee, Kyung-Su Park, Young-Seoub Hong, Seok-Joon Sohn, Yong-Dae Kim, Byung-Sun Choi, Ji-Ae Lim, Ho-Jang Kwon, Heon Kim, Jung-Duck Park
Cadmium (Cd) is the most potent nephrotoxic heavy metal and may affect bone; it also has a long biological half-life in the human body. This study was designed to assess the effect of environmental low-level Cd exposure on kidney function and bone in the general population. The subjects of this cross-sectional study were 1907 healthy Korean adults who had not been exposed to Cd occupationally. We analyzed the concentrations of Cd in the urine, markers of renal tubule damage, such as β2-microglobulin (β2-MG) and N-acetyl-β-D-glucosaminidase (NAG) activity in the urine, calculated the estimated glomerular filtration rate (eGFR) using serum creatinine, and measured bone mineral density (BMD)...
August 17, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28819637/cigarette-smoking-and-its-hazards-in-kidney-transplantation
#20
REVIEW
Muhammad Abdul Mabood Khalil, Jackson Tan, Said Khamis, Muhammad AshhadUllah Khalil, Rabeea Azmat, Arslan Rahat Ullah
Cigarette smoking affects many organs. It causes vasoconstriction through activation of sympathetic nervous system which leads to elevation of blood pressure and reduction in glomerular filtration rate and filtration pressure. It also causes thickening of renal arterioles. Cigarette smoking increases the risk of microalbuminuria and accelerates progression of microalbuminuria to macroalbuminuria. Furthermore, it causes rapid loss of glomerular filtration rate in chronic kidney disease patients. After kidney donation, these factors may be injurious to the solitary kidney...
2017: Advances in Medicine
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