keyword
MENU ▼
Read by QxMD icon Read
search

luyten

keyword
https://www.readbyqxmd.com/read/28816769/do-psychosocial-factors-predict-muscle-strength-pain-or-physical-performance-in-patients-with-knee-osteoarthritis
#1
Isabel A C Baert, Mira Meeus, Armaghan Mahmoudian, Frank P Luyten, Jo Nijs, Sabine M P Verschueren
OBJECTIVE: The aim of this study was to examine the relationship of psychosocial factors, namely, pain catastrophizing, kinesiophobia, and maladaptive coping strategies, with muscle strength, pain, and physical performance in patients with knee osteoarthritis (OA)-related symptoms. METHODS: A total of 109 women (64 with knee OA-related symptoms) with a mean age of 65.4 years (49-81 years) were recruited for this study. Psychosocial factors were quantified by the Pain Catastrophizing Scale, Tampa Scale for Kinesiophobia, and Pain Coping Inventory...
August 14, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28765085/a-preregistered-direct-replication-attempt-of-the-retrieval-extinction-effect-in-cued-fear-conditioning-in-rats
#2
Laura Luyten, Tom Beckers
In 2009, Monfils and colleagues proposed a behavioral procedure that was said to result in a permanent attenuation of a previously established fear memory, thereby precluding a possible return of fear after extinction (Monfils, Cowansage, Klann, & LeDoux, 2009). By presenting a single retrieval trial one hour before standard extinction training, they found an enduring reduction of fear. The retrieval-extinction procedure holds great clinical potential, particularly for anxiety patients, but the findings are not undisputed, and several conceptual replications have failed to reproduce the effect...
July 29, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28745946/mentalization-based-treatment-for-borderline-personality-disorder-in-adults-and-adolescents-for-whom-when-and-how
#3
Dine J Feenstra, Patrick Luyten, Dawn L Bales
Borderline personality disorder (BPD) is common in clinical practice. Psychotherapy is the treatment of choice, and mentalization-based treatment (MBT) is one of the empirically supported treatments that are currently available. For adults, two variants of MBT (MBT day hospital [MBT-DH] and MBT intensive outpatient [MBT-IOP]) have been developed and empirically evaluated. The authors review research on the development, efficacy, and implementation of MBT. In conclusion, the authors focus on the implementation of treatment programs for BPD patients...
July 26, 2017: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/28740372/pharmacological-treatment-of-osteoporosis-in-the-oldest-old
#4
REVIEW
A Vandenbroucke, F P Luyten, J Flamaing, E Gielen
The incidence of osteoporotic fractures increases with age. Consequently, the global prevalence of osteoporotic fractures will increase with the aging of the population. In old age, osteoporosis is associated with a substantial burden in terms of morbidity and mortality. Nevertheless, osteoporosis in old age continues to be underdiagnosed and undertreated. This may, at least partly, be explained by the fact that evidence of the antifracture efficacy of osteoporosis treatments comes mainly from randomized controlled trials in postmenopausal women with a mean age of 70-75 years...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28680639/subtypes-of-borderline-personality-disorder-patients-a-cluster-analytic-approach
#5
Maaike L Smits, Dine J Feenstra, Dawn L Bales, Jasmijn de Vos, Zwaan Lucas, Roel Verheul, Patrick Luyten
BACKGROUND: The borderline personality disorder (BPD) population is notably heterogeneous, and this has potentially important implications for intervention. Identifying distinct subtypes of patients may represent a first step in identifying which treatments work best for which individuals. METHODS: A cluster-analysis on dimensional personality disorder (PD) features, as assessed with the SCID-II, was performed on a sample of carefully screened BPD patients (N = 187) referred for mentalization-based treatment...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28675858/mentalization-in-adults-with-attention-deficit-hyperactivity-disorder-comparison-with-controls-and-patients-with-borderline-personality-disorder
#6
Nader Perroud, Deborah Badoud, Sébastien Weibel, Rosetta Nicastro, Roland Hasler, Anne-Lise Küng, Patrick Luyten, Peter Fonagy, Alexandre Dayer, Jean-Michel Aubry, Paco Prada, Martin Debbané
Emotion dysregulation and interpersonal hardships constitute core features of borderline personality disorder (BPD). Research has established the link between these core dysregulations and fluctuations in the capacity to appreciate the mental states that underlie behavior (mentalizing, operationalized as reflective functioning (RF)). As emotion dysregulation and interpersonal hardships also characterize adults with attention deficit hyperactivity disorder (ADHD), this study sought to examine the potential RF impairments affecting this population...
June 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28675808/delayed-primary-palatal-closure-in-resource-poor-countries-speech-results-in-ugandan-older-children-and-young-adults-with-cleft-lip-and-palate
#7
Laura Bruneel, Anke Luyten, Kim Bettens, Evelien D'haeseleer, Cleo Dhondt, Andrew Hodges, George Galiwango, Hubert Vermeersch, Kristiane Van Lierde
AIMS: Unrepaired clefts still regularly occur in resource-poor countries as a result of limited health-care access. The purpose of the present study was to report resonance, airflow and articulation characteristics following delayed (≥8years) primary palatal closure. METHODS: Fifteen Ugandan participants with cleft (lip and) palate (CP±L) were included as well as 15 age- and gender-matched Ugandan subjects without clefts. Palatal closure was performed at a mean age of 15;10 years using the Sommerlad technique...
June 20, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28674505/vulnerability-or-sensitivity-to-the-environment-methodological-issues-trends-and-recommendations-in-gene-environment-interactions-research-in-human-behavior
#8
REVIEW
Caroline Leighton, Alberto Botto, Jaime R Silva, Juan Pablo Jiménez, Patrick Luyten
Research on the potential role of gene-environment interactions (GxE) in explaining vulnerability to psychopathology in humans has witnessed a shift from a diathesis-stress perspective to differential susceptibility approaches. This paper critically reviews methodological issues and trends in this body of research. Databases were screened for studies of GxE in the prediction of personality traits, behavior, and mental health disorders in humans published between January 2002 and January 2015. In total, 315 papers were included...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28618001/three-dimensional-cell-culture-models-for-anticancer-drug-screening-worth-the-effort
#9
REVIEW
Eddy-Tim Verjans, Jordi Doijen, Walter Luyten, Bart Landuyt, Liliane Schoofs
High attrition of new oncology drug candidates in clinical trials is partially caused by the poor predictive capacity of artificial monolayer cell culture assays early in drug discovery. Monolayer assays do not take the natural three-dimensional (3D) microenvironment of cells into account. As a result, false positive compounds often enter clinical trials, leading to high dropout rates and a waste of time and money. Over the past two decades, tissue engineers and cell biologists have developed a broad range of 3D in vitro culturing tools that better represent in vivo cell biology...
June 15, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28603948/limb-derived-cells-as-a-paradigm-for-engineering-self-assembling-skeletal-tissues
#10
Warnakulasuriya A Fernando, Ioannis Papantoniou, Luis F Mendes, Gabriella Nilsson Hall, Kathleen Bosmans, Wai L Tam, Liliana M Teixeira, Malcolm Moos, Liesbet Geris, Frank P Luyten
Mimicking developmental events has been proposed as a strategy to engineer tissue constructs for regenerative medicine. However, this approach has not yet been investigated for skeletal tissues. Here we demonstrate that ectopic implantation of mouse embryonic day 14.5 long bone anlagen, dissociated into single cells and randomly incorporated in a bioengineered construct, give rise to epiphyseal growth plate like structures, bone, and marrow, which share many morphological and molecular similarities to epiphyseal units that form after transplanting intact long bone anlage, demonstrating substantial robustness and autonomy of complex tissue self-assembly and the overall organogenesis process...
June 11, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28594312/warning-about-the-use-of-critical-size-defects-for-the-translational-study-of-bone-repair-analysis-of-a-sheep-tibial-model
#11
Johan Lammens, Marina Maréchal, Lisbet Geris, Joshua Van der Aa, Hadewych Van Hauwermeiren, Frank P Luyten, Hendrik Delport
The repair of large long bone defects requires complex surgical procedures as the bone loss cannot simply be replaced by autologous grafts due to an insufficient bone stock of the human body. Tissue engineering strategies and the use of Advanced Therapy Medicinal Products (ATMPs) for these reconstructions remain a considerable challenge, in particular since robust outcomes in well-defined large animal models are lacking. To be suitable as a model for treatment of human sized bone defects, we developed a large animal model in both skeletally immature and mature sheep and made close observations on the spontaneous healing of defects...
July 3, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28575752/dynamic-and-static-knee-alignment-at-baseline-predict-structural-abnormalities-on-mri-associated-with-medial-compartment-knee-osteoarthritis-after-2-years
#12
Armaghan Mahmoudian, Jaap H van Dieёn, Sjoerd M Bruijn, Isabel A C Baert, Gert S Faber, Frank P Luyten, Sabine M P Verschueren
BACKGROUND: Dynamic and static varus alignment, both, have been reported as risk factors associated with structural progression of knee osteoarthritis. However the association of none of the static and dynamic alignment with structural, clinical, and functional progression associated with knee osteoarthritis has not been assessed yet in a longitudinal study. METHODS: Forty-seven women with early and established medial knee osteoarthritis were evaluated. Static and dynamic alignment as well as MRI detected structural features, clinical, and functional characteristics of patients were assessed at baseline and at 2 years follow-up...
May 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28574598/integrin-linked-kinase-regulates-bone-formation-by-controlling-cytoskeletal-organization-and-modulating-bmp-and-wnt-signaling-in-osteoprogenitors
#13
Marian Dejaeger, Anna-Marei Böhm, Naomi Dirckx, Joke Devriese, Elena Nefyodova, Ruben Cardoen, René St-Arnaud, Jos Tournoy, Frank P Luyten, Christa Maes
Cell-matrix interactions constitute a fundamental aspect of skeletal cell biology and play essential roles in bone homeostasis. These interactions are primarily mediated by transmembrane integrin receptors, which mediate cell adhesion and transduce signals from the extracellular matrix to intracellular responses via various downstream effectors, including integrin-linked kinase (ILK). ILK functions as adaptor protein at focal adhesion sites, linking integrins to the actin cytoskeleton, and has been reported to act as a kinase phosphorylating signaling molecules such as GSK-3β and Akt...
June 2, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28569524/mentalizing-as-a-mechanism-of-change-in-the-treatment-of-patients-with-borderline-personality-disorder-a-parallel-process-growth-modeling-approach
#14
Celine De Meulemeester, Kristof Vansteelandt, Patrick Luyten, Benedicte Lowyck
Although a number of effective psychotherapeutic treatments have been developed for borderline personality disorder (BPD), little is known about the mechanisms of change explaining the effects of these treatments. There is increasing evidence that impairments in mentalizing or reflective functioning-the capacity to reflect on the internal mental states of the self and others-are a central feature of BPD. To date, no study has directly investigated the core assumption of the mentalization-based approach to BPD, that changes in this capacity are associated with treatment outcome in BPD patients...
June 1, 2017: Personality Disorders
https://www.readbyqxmd.com/read/28543929/prevalence-and-impact-of-childhood-adversities-and-post-traumatic-stress-disorder-in-women-with-fibromyalgia-and%C3%A2-chronic-widespread-pain
#15
E Coppens, P Van Wambeke, B Morlion, N Weltens, H Giao Ly, J Tack, P Luyten, L Van Oudenhove
OBJECTIVE: This study investigates the prevalence of different types of childhood adversities (CA) and posttraumatic stress disorder (PTSD) in female patients with Fibromyalgia or Chronic Widespread Pain (FM/CWP) compared to patients with Functional Dyspepsia (FD) and achalasia. In FM/CWP, we also investigated the association between CA and PTSD on the one hand and pain severity on the other. METHODS: Patient samples consisted of 154 female FM/CWP, 83 female FD and 53 female achalasia patients consecutively recruited from a tertiary care hospital...
May 24, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28506841/definition-of-a-critical-size-osteochondral-knee-defect-and-its-negative-effect-on-the-surrounding-articular-cartilage-in-the-rat
#16
H Katagiri, L F Mendes, F P Luyten
BACKGROUND: Joint trauma is predisposing to the incidence of osteoarthritis (OA) of the knee. There is a limited knowledge on the impact of posttraumatic osteochondral defects on the whole joint. This study was designed to define a critical size osteochondral defect in the knee of rats and to investigate a possible association between osteochondral defects and degeneration of the surrounding joint surface. METHODS: Cylindrical osteochondral defects of different sizes were created in the knee joint of rats...
September 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28472162/the-parental-reflective-functioning-questionnaire-development-and-preliminary-validation
#17
Patrick Luyten, Linda C Mayes, Liesbet Nijssens, Peter Fonagy
This paper reports on three studies on the development and validation of the Parental Reflective Functioning Questionnaire (PRFQ), a brief, multidimensional self-report measure that assesses parental reflective functioning or mentalizing, that is, the capacity to treat the infant as a psychological agent. Study 1 investigated the factor structure, reliability, and relationships of the PRFQ with demographic features, symptomatic distress, attachment dimensions, and emotional availability in a socially diverse sample of 299 mothers of a child aged 0-3...
2017: PloS One
https://www.readbyqxmd.com/read/28448663/prame-as-a-potential-target-for-immunotherapy-in-metastatic-uveal-melanoma
#18
Gülçin Gezgin, Sietse J Luk, Jinfeng Cao, Mehmet Dogrusöz, Dirk M van der Steen, Renate S Hagedoorn, Daniëlle Krijgsman, Pieter A van der Velden, Matthew G Field, Gregorius P M Luyten, Karoly Szuhai, J William Harbour, Ekaterina S Jordanova, Mirjam H M Heemskerk, Martine J Jager
Importance: Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentially expressed antigen in melanoma), which can potentially be targeted by adoptive T-cell therapy. Objective: To determine whether there may be a rationale for PRAME-directed T-cell therapy for metastatic UM. Design, Setting, and Participants: An experimental study using a retrospective cohort of 64 patients with UM (median follow-up, 62 months) was conducted from January 8, 2015, to November 20, 2016, at the Leiden University Medical Center...
June 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28447814/undetected-scars-self-criticism-attachment-and-romantic-relationships-among-otherwise-well-functioning-childhood-sexual-abuse-survivors
#19
Dana Lassri, Patrick Luyten, Peter Fonagy, Golan Shahar
BACKGROUND: Studies have consistently demonstrated the negative impact of childhood sexual abuse (CSA) on intimate relationships. The majority of studies have focused on revictimization in at-risk or clinical samples, with very few addressing the impact of CSA on otherwise well-functioning adults and even fewer investigating the psychological mechanisms involved. To fill this gap, this study focuses on the effect of CSA on "normative" (nonviolent) romantic relationships in otherwise well-functioning young women, and the mediating role of personality dimension self-criticism and attachment in this regard...
April 27, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28434823/influence-of-serum-and-polystyrene-plate-type-on-stability-of-candida-albicans-biofilms
#20
Purity N Kipanga, Walter Luyten
Adhesion is a crucial initial step in microbial biofilm formation. Firm attachment to a target surface subsequently ensures successful colonization and survival despite turbulent conditions. In the laboratory, polystyrene plates are commonly used in biofilm experiments and the 'washing/rinse steps' before staining are critical for assaying biofilm viability. However, these rinse steps risk the removal (partially or entirely) of the formed biofilm, resulting in inconsistent results. The aim of the present study was to optimize conditions for firmer biofilms, less prone to disruption and thus significantly reducing well-to-well variability...
April 21, 2017: Journal of Microbiological Methods
keyword
keyword
81652
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"