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https://www.readbyqxmd.com/read/29052257/utility-of-reproductive-life-plans-in-identification-of-potentially-teratogenic-medication-use-a-pilot-study
#1
Natalie DiPietro Mager, Caitlin Mills, April Snelling
BACKGROUND: Teratogenic medications increase risks of miscarriage, fetal death, and/or birth defects. It is important to identify whether women of childbearing potential are taking these medications and to minimize exposure to these agents through change in drug therapy before conception and/or use of effective contraception to prevent conception. OBJECTIVE: To determine the utility of reproductive life plans as tools to identify women using potentially teratogenic medications...
October 20, 2017: Birth
https://www.readbyqxmd.com/read/28759402/access-to-emergency-contraception-after-removal-of-age-restrictions
#2
COMPARATIVE STUDY
Tracey A Wilkinson, Porsche Clark, Sally Rafie, Aaron E Carroll, Elizabeth Miller
BACKGROUND: Levonorgestrel emergency contraception (EC) is safe and effective for postcoital pregnancy prevention. Starting in 2013, the US Food and Drug Administration removed age restrictions, enabling EC to be sold over the counter to all consumers. We sought to compare the availability and access for female adolescents with the 2012 study, using the same study design. METHODS: Female mystery callers posing as 17-year-old adolescents in need of EC used standardized scripts to telephone 979 pharmacies in 5 US cities...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28721311/from-kaua-i-to-hawai-i-island-interisland-differences-in-emergency-contraceptive-pill-availability
#3
Holly Bullock, Mary Tschann, Jennifer Elia, Bliss Kaneshiro, Jennifer Salcedo
Emergency contraceptive pills (ECPs) are medications used after unprotected intercourse, underprotected intercourse, or sexual assault to decrease the risk of pregnancy. Availability of ECPs in Hawai'i's retail pharmacies was last assessed in 2007, following over-the-counter access to levonorgestrel ECPs (LNG-ECP) for women age 18 years or older and prior to U.S. Food and Drug Administration (FDA) approval of prescription-only ulipristal acetate (UPA). We conducted a county-by-county subanalysis from a larger observational population-based study on statewide availability of ECPs in Hawai'i's pharmacies...
July 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28639423/emergency-contraceptive-pill-users-risk-perceptions-for-sexually-transmitted-infections-and-future-unintended-pregnancy
#4
Mary T Hickey, Michele G Shedlin
BACKGROUND AND PURPOSE: The availability of emergency contraception pills (ECP) over the counter (OTC) has the potential to reduce the incidence of unintended pregnancy; however, the increased risk for sexually transmitted infection (STI) acquisition, related to unprotected intercourse, has not been adequately addressed. The purpose of this study is to gain insight into risk perceptions for STIs and subsequent unintended pregnancy in women who have purchased ECP OTC. METHODS: Twenty-one women, aged 18-24, attending a private university in an urban setting, who purchased and used ECP OTC participated in 1-h, individual interviews...
September 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28551410/perceptions-and-attitudes-of-community-pharmacists-toward-professional-ethics-and-ethical-dilemmas-in-the-workplace
#5
Jadranka Vuković Rodríguez, Živka Juričić
BACKGROUND: Formal training in pharmacy ethics is relatively new in Croatia, and the professional code of ethics is more than 20 years old. Very little is known about how practicing pharmacists implement ethical considerations and relevant professional guidelines in their work. OBJECTIVES: This study aimed to provide the first description of the perceptions and attitudes of Croatian community pharmacists toward ethics in pharmacy practice, how often they face certain ethical dilemmas and how they resolve them...
May 22, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28442191/barriers-to-single-dose-levonorgestrel-only-emergency-contraception-access-in-retail-pharmacies
#6
Van Mimi Chau, Carol A Stamm, Laura Borgelt, Michelle Gaffaney, Alia Moore, Rachel Z Blumhagen, Leanne Rupp, Daniel Topp, Christine Gilroy
OBJECTIVES: In February 2014, the Food and Drug Administration updated its regulations to make all single-dose levonorgestrel-only emergency contraception (LNG-EC) available over the counter. This study examines the availability and access to LNG-EC shortly after this policy change, and any additional barriers to obtaining LNG-EC in Colorado retail pharmacies. STUDY DESIGN: From June to July 2014, three female interviewers posing as women seeking LNG-EC conducted a telephone survey of all 633 Colorado retail pharmacies listed in The Little Blue Book (2014) phone directory...
September 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28349341/knowledge-and-opinion-of-pharmacists-on-emergency-contraceptive-pills-in-hungary
#7
Melinda Vanya, Maria Matuz, Ria Benko, Reka Viola, Attila Horvath-Sziklai, Gyongyvér Soos, Gyorgy Bartfai
Background Emergency contraceptive pills (ECPs) are used to prevent unintended pregnancy. There is a worldwide intention to improve access to ECPs; therefore, identifying potential barriers to introducing over-the counter (OTC) access is of utmost importance. As pharmacists are the key personnel to convey accurate drug information, their knowledge and attitude on ECPs is important. Objective We aimed to conduct a nationwide study to assess pharmacists' knowledge on ECPs and to survey their opinion on sales category change of ECPs (i...
June 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28344968/pulmonary-embolism-in-a-healthy-woman-using-the-oral-contraceptives-containing-desogestrel
#8
Min-Jeong Park, Gyun-Ho Jeon
Venous thromboembolism is well known as one of the rare but serious adverse effects of combined oral contraceptives (COCs). The COCs with third and fourth generation progestogens were found to have higher risk of venous thrombosis than those with second generation progestogens. We present a case of pulmonary embolism in a 23-year-old nulligravid woman who was using COCs containing the third generation progestogen (desogestrel). At the time of presentation of the adverse effect, she had been using the COCs for 4 months...
March 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28314704/over-the-counter-access-to-oral-contraceptives-for-adolescents
#9
REVIEW
Krishna K Upadhya, John S Santelli, Tina R Raine-Bennett, Melissa J Kottke, Daniel Grossman
Oral contraceptives (OCs) are used by millions of women in the U.S. The requirement to obtain OCs by prescription from a clinician may serve as a barrier to contraceptive initiation and continuation for women, in particular adolescents. Over-the-counter (OTC) availability would reduce this barrier and could further reduce unintended pregnancy rates. This review explores the scientific issues and regulatory processes involved in switching OCs to OTC status for minor adolescents. We review: (1) the regulatory criteria for switching a drug to OTC status; (2) risk of pregnancy and safety during use of OCs including combined oral contraceptives and progestin-only pills for adolescents; (3) the ability of adolescents to use OCs consistently and correctly; (4) OTC access to OCs and potential effect on sexual risk behaviors; and (5) the potential for reduced opportunities for clinicians to counsel and provide recommended reproductive health care to adolescents...
June 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28283499/metabolite-identification-reaction-phenotyping-and-retrospective-drug-drug-interaction-predictions-of-17-deacetylnorgestimate-the-active-component-of-the-oral-contraceptive-norgestimate
#10
Deepak Ahire, Sarmistha Sinha, Barry Brock, Ramaswamy Iyer, Sandhya Mandlekar, Murali Subramanian
Ortho-Tri-Cyclen® (OTC), a two drug cocktail comprising of ethinylestradiol (EE) and norgestimate (13-ethyl-17-acetoxy-18, 19-dinor-17α-pregn-4-en-20yn-3 oxime), is commonly prescribed to avert unwanted pregnancies in women of reproductive age. In vivo, norgestimate undergoes extensive and rapid deacetylation to produce 17-deacetylnorgestimate (NGMN), an active circulating metabolite that likely contributes significantly to norgestimate efficacy. Despite being of primary significance, the metabolism and reaction phenotyping of NGMN have not been previously reported...
March 10, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/28042350/evaluating-the-practice-of-iranian-community-pharmacists-regarding-oral-contraceptive-pills-using-simulated-patients
#11
Nazanin Foroutan, Fatemeh Dabaghzadeh
BACKGROUND: As oral contraceptive pills are available over the counter in pharmacies, pharmacists are professionally responsible for checking and informing patients about every aspect of taking these drugs. Simulated patient method is a new and robust way to evaluate professional performance of pharmacists. OBJECTIVE: The aim of the present study was to evaluate the pharmacy practice of Iranian pharmacists regarding over-the-counter use of oral contraceptive pills using simulated patient method...
October 2016: Pharmacy Practice
https://www.readbyqxmd.com/read/27896473/experience-with-oral-emergency-contraception-since-the-otc-switch-in-germany
#12
Marion Kiechle, Miriam Neuenfeldt
PURPOSE: In March 2015, the oral emergency contraceptives levonorgestrel (LNG) and ulipristal acetate (UPA) were released from prescription-only status in Germany. The main research question is to analyse whether the OTC status of oral emergency contraceptives has an influence on the patterns of use. METHODS: All information is based on searches for public domain sources on emergency contraception. Searches were made for scientific publications, statistics, and surveys...
March 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27785169/non-prescription-dispensing-of-emergency-oral-contraceptives-recommendations-from-the-german-federal-chamber-of-pharmacists-bundesapothekerkammer
#13
Martin Schulz, Ralf Goebel, Claudia Schumann, Petra Zagermann-Muncke
BACKGROUND: Emergency hormonal contraceptives (EHC) are contraceptives used to prevent unintended pregnancy following unprotected sexual intercourse (USI) or contraceptive failure. The EHCs available without a prescription include medicines containing levonorgestrel (LNG) in more than 80 countries and, recently, based on an EU-switch ellaOne®, which contains ulipristal acetate (UPA). EHCs work by stopping or delaying ovulation. Those containing LNG can be used up to 72 hours after USI or contraceptive failure, while UPA can be used up to 120 hours...
July 2016: Pharmacy Practice
https://www.readbyqxmd.com/read/27683515/investigation-of-social-demographic-and-health-variations-in-the-usage-of-prescribed-and-over-the-counter-medicines-within-a-large-cohort-south-yorkshire-uk
#14
Mark A Green, Emma Little, Richard Cooper, Clare Relton, Mark Strong
OBJECTIVES: Prescribed and over-the-counter (non-prescribed) medicine usage has increased in recent years; however, there has been less investigation of the socioeconomic predictors of use. This has been due to a lack of data, especially for over-the-counter medicines. Our study aims to understand how prescribed and over-the-counter medicine patterns vary by demographic, social and health characteristics within a large population cohort. DESIGN: Cross-sectional data analysis...
2016: BMJ Open
https://www.readbyqxmd.com/read/27682018/access-to-emergency-contraception-in-the-over-the-counter-era
#15
Kelly Cleland, Jamie Bass, Florida Doci, Angel M Foster
INTRODUCTION: After years of complex regulatory changes, levonorgestrel (LNG) emergency contraception (EC) is now approved for unrestricted sale in the United States. Timely access to EC pills is critical because they are more likely to work the sooner they are taken. This study assesses whether LNG EC is sold in accordance with current Food and Drug Administration regulations. METHODS: We distributed an online questionnaire through an EC-focused listserv for reproductive health professionals, asking data collectors to visit local stores and document product names, price, over-the-counter shelf availability, and misinformation about age restrictions...
November 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/27486050/the-power-of-the-patient-question-a-secret-shopper-study
#16
Joanne Peters, Karishma Desai, Daniel Ricci, Dan Chen, Monny Singh, Betty Chewning
OBJECTIVES: To examine the effect of one standardized patient question on the length, number and type of new topics pharmacists addressed. To explore how community pharmacists counsel secret shoppers on two types of over-the-counter (OTC) medications-ibuprofen (IB) and emergency contraceptives (EC). METHODS: 25 pharmacists from 7 independent, midwestern community pharmacies consented to have secret shoppers purchase an OTC medication and to have their consultations audio-recorded...
September 2016: Patient Education and Counseling
https://www.readbyqxmd.com/read/27385872/evaluation-of-pharmacists-services-for-dispensing-emergency-contraceptive-pills-in-delhi-india-a-mystery-shopper-study
#17
Pikee Saxena, Archana Mishra, Aruna Nigam
BACKGROUND: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. OBJECTIVE: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. MATERIAL AND METHODS: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery shoppers posed as customers over a period of 6 months...
July 2016: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/27321899/sexual-and-contraceptive-behaviors-among-adolescents-requesting-emergency-contraception
#18
Carrie Cwiak, Brandon Howard, Jennifer Hsieh, Nancy Ricciotti, Gina S Sucato
STUDY OBJECTIVE AND DESIGN: Unintended pregnancy rates in the United States remain high among adolescents. Emergency contraception (EC) provides the only option for pregnancy prevention after unprotected sex. To better define the population of adolescents who request and use EC pills, we performed a post hoc analysis of an over-the-counter simulation study of EC pills. SETTING: Teen reproductive health clinics in 5 cities. PARTICIPANTS: Adolescents between the ages of 13 and 17 years who requested EC...
December 2016: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27293493/important-but-incomplete-plan-b-as-an-avenue-for-post-assault-care
#19
Michelle L Munro, Kristy K Martyn, Rebecca Campbell, Sandra Graham-Bermann, Julia S Seng
Many survivors of rape do not seek post-assault care. The recent change in status of emergency contraception (EC), such as Plan B, to an over-the-counter (OTC) product may be further changing post-assault care-seeking. This descriptive study will quantify OTC EC use in the post-assault period and elicit survivors' desires for care. Data were collected from women purchasing OTC EC at university pharmacies (n=55) and students in an undergraduate university class (n=165). Quantitative results indicate annual prevalence rates of post-assault OTC EC use as 5...
December 2015: Sexuality Research & Social Policy
https://www.readbyqxmd.com/read/27261868/emergency-contraception
#20
REVIEW
Pelin Batur, Lisa N Kransdorf, Petra M Casey
Emergency contraception (EC) may help prevent pregnancy in various circumstances, such as contraceptive method failure, unprotected sexual intercourse, or sexual assault, yet it remains underused. There are 4 approved EC options in the United States. Although ulipristal acetate requires a provider's prescription, oral levonorgestrel (LNG) is available over the counter for women of all ages. The most effective method of EC is the copper intrauterine device, which can be left in place for up to 10 years for efficacious, cost-effective, hormone-free, and convenient long-term primary contraception...
June 2016: Mayo Clinic Proceedings
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