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https://www.readbyqxmd.com/read/27928876/increased-levels-of-alphab-crystallin-in-vitreous-fluid-of-patients-with-proliferative-diabetic-retinopathy-and-correlation-with-vascular-endothelial-growth-factor
#1
Wei Chen, Qianyi Lu, Li Lu, Huaijin Guan
BACKGROUND: AlphaB-crystallin has been shown to have angiogenic properties. The purpose of this study was to determine the levels of alphaB-crystallin in the vitreous fluid of patients with proliferative diabetic retinopathy (PDR) and to confirm the association between the expression level of alphaB-crystallin and vascular endothelial growth factor (VEGF). METHODS: Vitreous samples were collected before vitrectomy from 46 eyes of 46 consecutive patients with PDR and 19 patients without diabetes mellitus (DM) had vitrectomy for idiopathic macular hole (IMH)...
December 7, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27913441/size-and-vitreomacular-attachment-of-primary-full-thickness-macular-holes
#2
Elise Philippakis, Franck Amouyal, Aude Couturier, Elise Boulanger-Scemama, Alain Gaudric, Ramin Tadayoni
PURPOSE: To study the relationship between the size of primary full-thickness macular hole (MH) and the vitreomacular attachment status. DESIGN: Single-centre retrospective observational case series. METHODS: The records of 100 consecutive eyes operated for primary full-thickness MH were retrospectively reviewed. The vitreous status and MH diameter were assessed on the preoperative optical coherence tomography scans. MH were classified depending on the presence or absence of vitreomacular traction (VMT) and their size as small (<250 µm), medium (250-400 µm) and large (>400 µm), as suggested in the International VMT Study Group Classification...
December 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27911448/inverted-internal-limiting-membrane-flap-technique-as-a-useful-procedure-for-macular-hole-associated-retinal-detachment-in-highly-myopic-eyes
#3
H Sasaki, A Shiono, J Kogo, R Yomoda, Y Munemasa, M Syoda, H Otake, H Kurihara, Y Kitaoka, H Takagi
PurposeTo determine whether the inverted internal limiting membrane (ILM) flap technique contributes to high reattachment and closure rates in patients with macular hole-associated retinal detachment (MHRD).Patients and methodsIn all, 15 eyes of 15 patients with MHRD undergoing 25-gauge pars plana vitrectomy with the inverted ILM flap technique or ILM peeling. The patients were divided into the inverted ILM flap technique group (6 eyes) and ILM peeling group (9 eyes). The logarithm of minimal angle of resolution best-corrected visual acuity (BCVA) and retinal attachment and macular hole closure rates were compared between the two groups before and after surgery...
December 2, 2016: Eye
https://www.readbyqxmd.com/read/27911425/-biometric-parameters-of-vitrectomized-eyes
#4
S V Asatryan, V K Surguch, S I Kharlap, T A Shchegoleva
AIM: To analyze changes in various biometric parameters after vitrectomy. MATERIAL AND METHODS: A total of 50 patients (50 eyes) were followed up. All of them underwent vitrectomy for idiopathic epiretinal fibrosis and macular hole. In addition to the standard ophthalmic examination, we performed a combined ultrasound study and ultrasound biomicroscopy before and after the surgery (at 2-3 weeks and 6 months). Variation statistics was applied to assess the results using the SPSS Statistica 20 software...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27902639/air-tamponade-combined-with-nonsupine-positioning-in-macular-hole-surgery-for-pseudophakic-eyes
#5
Vegard A Forsaa, Jørgen Krohn
PURPOSE: To investigate the closure rate of primary full-thickness macular hole, following intraocular air tamponade combined with a nonsupine positioning regimen. METHODS: A prospective study of patients with full-thickness macular hole, who underwent pars plana vitrectomy with internal limiting membrane peeling and intraocular air tamponade followed by 3 days of nonsupine positioning. Outcome measures were primary full-thickness macular hole closure and improvement in best-corrected visual acuity after 6 months...
November 29, 2016: Retina
https://www.readbyqxmd.com/read/27898707/long-term-changes-in-intraocular-pressure-after-vitrectomy-for-rhegmatogenous-retinal-detachment-epi-retinal-membrane-or-macular-hole
#6
Kentaro Yamamoto, Takeshi Iwase, Hiroko Terasaki
PURPOSE: To determine the long-term changes in the intraocular pressure (IOP) following vitrectomy for rhegmatogenous retinal detachment (RRD), epiretinal membrane (ERM), and macular hole (MH), and to investigate the relationship between the retinal disease and the incidence of late-onset IOP elevation. METHODS: This was a retrospective, observational, comparative study. We reviewed the medical records of 54 eyes of 54 RRD patients, 117 eyes of 117 ERM patients, and 75 eyes of 75 MH patients who underwent 20-, 23- or 25-gauge vitrectomy...
2016: PloS One
https://www.readbyqxmd.com/read/27893098/vitreal-cytokine-profile-differences-between-eyes-with-epiretinal-membranes-or-macular-holes
#7
Souska Zandi, Christoph Tappeiner, Isabel B Pfister, Alain Despont, Robert Rieben, Justus G Garweg
Purpose: Cytokines play an important role in cell signaling in inflammatory and repair processes, also within the posterior segment of the eye. These molecules are thus implicated in the pathophysiology of several vitreoretinal diseases. In the present study, we compared vitreal cytokine profiles in patients with idiopathic epiretinal membranes (ERMs) and idiopathic full-thickness macular holes (MHs) without epiretinal membranes. Methods: Native vitreal humor was collected during elective pars plana vitrectomy for the treatment of macular pathologies (group 1: ERM; group 2: MH) from patients without any other ocular or systemic disease...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27889502/role-of-lamellar-hole-associated-epiretinal-proliferation-in-lamellar-macular-holes
#8
Roberto dell'Omo, Gianni Virgili, Stanislao Rizzo, Serena De Turris, Giovanni Coclite, Dario Giorgio, Ermanno dell'Omo, Ciro Costagliola
PURPOSE: To compare the morphologic and functional characteristics and response to surgery of lamellar macular holes (LMHs) with and without lamellar hole-associated epiretinal proliferation (LHEP) and standard epiretinal membrane (ERM). DESIGN: Retrospective observational case series. METHODS: Setting: Vitreoretinal clinical practice. STUDY POPULATION: Eigthy-four eyes of 84 patients. The included eyes must present an irregular foveal contour and schitic or cavitated lamellar separation of neurosensory retina on spectral-domain optical coherence tomography (SD-OCT) and an area of increased autofluorescence on blue- fundus autofluorescence (B-FAF)...
November 23, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27885039/th17-cell-frequency-and-il-17a-concentrations-in-peripheral-blood-mononuclear-cells-and-vitreous-fluid-from-patients-with-diabetic-retinopathy
#9
Hui Chen, Xiangrong Ren, Nanying Liao, Feng Wen
OBJECTIVE: To quantify T helper (Th)17 cells and determine interleukin (IL)-17A levels in peripheral blood mononuclear cell (PBMC) culture and vitreous fluid from patients with type 2 diabetes mellitus (T2DM) with diabetic retinopathy (DR). METHODS: Th17 cell frequency and IL-17A concentrations in PBMCs from 60 patients with T2DM with DR, 30 without DR and 30 sex- and age-matched healthy individuals were measured by flow cytometry and enzyme-linked immunosorbent assay (ELISA), respectively...
November 24, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27881586/iatrogenic-parafoveal-macular-hole-following-nd-yag-posterior-hyaloidotomy-for-premacular-haemorrhage
#10
Ravi Bypareddy, Rohan Chawla, Shorya Vardhan Azad, Brijesh Takkar
Premacular sub-internal limiting membrane (sub-ILM) haemorrhage is a known cause of sudden profound loss of vision. Neodymium-doped yttrium aluminium garnet (ND-YAG) posterior hyaloidotomy is an inexpensive, effective and safe treatment modality for rapid drainage of haemorrhage covering the macula. An 18-year-old male patient presented to us with a history of Nd-YAG posterior hyaloidotomy for Valsalva-related premacular bleed. At the posterior pole, a cavity formed by the detached ILM with a central defect in ILM-posterior hyaloid complex was evident...
November 23, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27853954/spectral-domain-optical-coherence-tomography-findings-in-idiopathic-lamellar-macular-hole
#11
Elena Zampedri, Federica Romanelli, Francesco Semeraro, Barbara Parolini, Rino Frisina
BACKGROUND: To evaluate demographic, functional, and morphological parameters of idiopathic lamellar macular hole (ILMH). METHODS: Observational longitudinal retrospective study. Optical coherence tomography examinations and corresponding clinical charts of a series of consecutive patients affected by ILMH, between January 2010 and March 2015, from the database of the Department of Ophthalmology of Trento Hospital, Italy, have been collected and examined. Demographic and functional parameters were: age (year), gender (male/female), eye (right/left), lens status, best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution (LogMAR)...
November 16, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27849651/duration-of-prone-positioning-after-macular-hole-surgery-determined-by-swept-source-optical-coherence-tomography
#12
Masahiko Sano, Makoto Inoue, Yuji Itoh, Yoshiyuki Kita, Kazunari Hirota, Takashi Koto, Akito Hirakata
PURPOSE: To compare the closure rate of macular hole closure and duration of the prone positioning after macular hole (MH) surgery with two protocols for halting the prone positioning. METHODS: The authors studied 129 eyes of 125 consecutive patients with MH who had undergone vitrectomy. In 60 eyes of 59 patients, the prone positioning was halted after detecting an MH closure in the swept-source optical coherence tomographic images (SS group). In 69 eyes of 66 patients, the prone position was halted by the surgeon's decision (conventional group)...
November 15, 2016: Retina
https://www.readbyqxmd.com/read/27847628/sulfur-hexafluoride-sf6-versus-perfluoropropane-c3f8-tamponade-and-short-term-face-down-position-for-macular-hole-repair-a-randomized-prospective-study
#13
Giamberto Casini, Pasquale Loiudice, Stefano De Cillà, Paolo Radice, Marco Nardi
BACKGROUND: To compare early visual and anatomical outcomes after either sulfur hexafluoride (SF6) or perfluoropropane (C3F8) tamponade for macular hole repair. METHODS: 147 eyes affected by primary full-thickness macular hole underwent pars plana vitrectomy with dye assisted removal of the internal limiting membrane and gas tamponade. Prone position was prescribed for 48 h after surgery. All patients were divided into 3 groups depending on the size of the hole: small (<250 µm), medium (>250-<400 µm) or large (>400 µm)...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27833968/posterior-vitreous-detachment-and-macular-anatomical-changes-a-tomographic-electroretinographic-study
#14
Alin Ştefan Ştefănescu-Dima, Cornelia Andreea Corîci, Maria Rodica Mănescu, Teodor Nicuşor Sas, Maria Iancău, Carmen LuminiŢa Mocanu
AIM: Posterior vitreous detachment (PVD) is a physiological phenomenon due to aging characterized by separation of the vitreous cortex from the retina and may induce a variety of pathological events at the vitreoretinal junction. The aim of this study is to highlight in vivo anatomical and functional changes in early stages of PVD allowing the correct treatment. MATERIAL AND METHODS: Non-consecutive case series; optical coherence tomography (OCT) relies on analyzing the reflectivity of coherent light from different anatomical interfaces within posterior vitreous and retinal histological layers, thus acquiring transverse sections through vitreoretinal interface, sensory retina, retinal pigment epithelium and choroid...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27832339/vitrectomy-and-scleral-imbrication-in-patients-with-myopic-traction-maculopathy-and-macular-hole-retinal-detachment
#15
Yoshimasa Ando, Akito Hirakata, Arisa Ohara, Reiji Yokota, Tadashi Orihara, Kazunari Hirota, Takashi Koto, Makoto Inoue
PURPOSE: To determine the outcomes of vitrectomy with scleral imbrication in highly myopic eyes with either myopic traction maculopathy (MTM) or macular hole retinal detachment (MHRD). METHODS: The medical records of 17 patients who had undergone vitrectomy with internal limiting membrane (ILM) peeling and scleral imbrication for MTM or MHRD were reviewed. The best-corrected visual acuities (BCVAs), the axial length, the macular hole (MH) closure rate, and the shape of the posterior segment determined by optical coherence tomography were evaluated...
November 10, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27831970/spontaneous-closure-of-a-macular-hole-after-four-failed-vitrectomies-in-the-setting-of-nf-1
#16
Kendall W Wannamaker, Robert A Sharpe, Jan A Kylstra
PURPOSE: To present the case of a patient who developed spontaneous closure of an idiopathic macular hole after four failed attempts at surgical closure. METHODS: This is a retrospective case review of the medical record of a single patient. No statistical analysis was performed. The patient is a 71-year-old white woman with neurofibromatosis Type 1 who presented to the retina clinic of one of the authors. RESULTS: The patient underwent four vitrectomies with long acting gas by two surgeons over the course of 2 years...
November 9, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27824317/concomitant-macular-hole-and-central-serous-chorioretinopathy-after-blunt-eye-trauma
#17
Kemal Tekin, Mehmet Citirik, Muhammed Atalay, Mehmet Yasin Teke
PURPOSE: To report concomitant macular hole and central serous chorioretinopathy after blunt trauma. METHODS: Case presentation. A 31-year-old man presented with a complaint of a reduction in visual acuity and blurred vision in the right eye after blunt eye trauma. The patient did not have a history of any systemic disorders and drug administration. RESULTS: On ocular examination, best corrected visual acuity was 2/20 in the right eye and 20/20 in the left eye...
October 11, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27813527/pneumatic-release-of-focal-vitreomacular-traction
#18
M G Claus, E Feron, M Veckeneer
PurposeTo study the efficacy of a single intravitreal injection of expansile gas as a valuable alternative to current treatment options (conservative, pharmacological, and surgical) in patients with symptomatic, focal vitreomacular traction (VMT).Patients and methodsThis study comprises a retrospective, interventional case series of patients. Twenty eyes in seventeen patients with symptomatic and persisting focal VMT were treated in an outpatient setting with an intravitreal gas injection of 0.2 ml. In 19 eyes, 100% hexafluoroethane (C2F6) was used...
November 4, 2016: Eye
https://www.readbyqxmd.com/read/27813165/successful-closure-of-full-thickness-macular-hole-associated-with-circumscribed-choroidal-haemangioma
#19
Vinod Kumar, Jatinder K Bhati, Raghav Ravani, Parijat Chandra, Atul Kumar
No abstract text is available yet for this article.
November 3, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27806814/visual-outcomes-of-macular-hole-surgery
#20
Hussain Ahmad Khaqan, Lubna, Farrukh Jameel, Muhammad
OBJECTIVE: To determine the mean visual improvement after internal limiting membrane (ILM) peeling assisted with brilliant blue staining of ILM in macular hole, and stratify the mean visual improvement in different stages of macular hole. STUDY DESIGN: Quasi-experimental study. PLACE AND DURATION OF STUDY: Eye outpatient department (OPD), Lahore General Hospital, Lahore from October 2013 to December 2014. METHODOLOGY: Patients with macular hole underwent measurement of best corrected visual acuity (BCVA) and fundus examination with indirect slit lamp biomicroscopy before surgery...
October 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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