Alessandra Coin, Marianna Noale, Pietro Gareri, Caterina Trevisan, Andrea Bellio, Filippo Fini, Angela Marie Abbatecola, Stefania Del Signore, Alba Malara, Enrico Mossello, Stefano Fumagalli, Stefano Volpato, Fabio Monzani, Giuseppe Bellelli, Gianluca Zia, Raffaele Antonelli Incalzi
BACKGROUND AND OBJECTIVES: Depression is highly prevalent in older adults, especially in those with dementia. Trazodone, an antidepressant, has shown to be effective in older patients with moderate anxiolytic and hypnotic activity; and a common off-label use is rising for managing behavioral and psychological symptoms of dementia (BPSD). The aim of the study is to comparatively assess the clinical profiles of older patients treated with trazodone or other antidepressants. METHODS: This cross-sectional study involved adults aged ≥ 60 years at risk of or affected with COVID-19 enrolled in the GeroCovid Observational study from acute wards, geriatric and dementia-specific outpatient clinics, as well as long-term care facilities (LTCF)...
May 19, 2023: European Geriatric Medicine