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https://www.readbyqxmd.com/read/28441271/alternative-payment-models-and-urology
#1
Deborah R Kaye, David C Miller, Chad Ellimoottil
PURPOSE OF REVIEW: The Medicare Access and CHIP Reauthorization Act (MACRA) is a historic bill that was recently passed that establishes how quality measurement and practice patterns will affect physician reimbursement. Alternative payment models (APMs) are an essential component of MACRA and Medicare's vision of paying for high-value care. This review describes APMs in the context of MACRA and their impact on urology. RECENT FINDINGS: The majority of urologists will be affected by MACRA...
April 22, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28441087/using-the-payoff-time-in-decision-analytic-models-a-case-study-for-using-statins-in-primary-prevention
#2
Alexander Thompson, Bruce Guthrie, Katherine Payne
BACKGROUND: The payoff time represents an estimate of when the benefits of an intervention outweigh the costs. It is particularly useful for benefit-harm decision making for interventions that have deferred benefits but upfront harms. The aim of this study was to expand the application of the payoff time and provide an example of its use within a decision-analytic model. METHODS: Three clinically relevant patient vignettes based on varying levels of estimated 10-year cardiovascular risk (10%, 15%, 20%) were developed...
March 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28440660/implementation-of-whole-slide-imaging-for-clinical-purposes-issues-to-consider-from-the-perspective-of-early-adopters
#3
Andrew J Evans, Mohamed E Salama, Walter H Henricks, Liron Pantanowitz
CONTEXT: - There is growing interest in the use of digital pathology, especially whole slide imaging, for diagnostic purposes. Many issues need to be considered when incorporating this technology into a clinical laboratory. The College of American Pathologists established a Digital Pathology Committee to support the development of College programs related to digital pathology. One of its many initiatives was a panel discussion entitled "Implementing Whole-Slide Imaging for Clinical Use: What to Do and What to Avoid," given for 3 years at the College's annual meetings starting in 2014...
April 25, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28440109/the-demography-of-words-the-global-decline-in-non-numeric-fertility-preferences-1993-2011
#4
Margaret Frye, Lauren Bachan
This paper examines the decline in non-numeric responses to questions about fertility preferences among women in the developing world. These types of response-such as 'don't know' or 'it's up to God'-have often been interpreted through the lens of fertility transition theory as an indication that reproduction has not yet entered women's 'calculus of conscious choice'. However, this has yet to be investigated cross-nationally and over time. Using 19 years of data from 32 countries, we find that non-numeric fertility preferences decline most substantially in the early stages of a country's fertility transition...
April 25, 2017: Population Studies
https://www.readbyqxmd.com/read/28440083/systems-metabolomics-for-prediction-of-metabolic-syndrome
#5
Estelle Pujos-Guillot, Marion Brandolini, Mélanie Pétéra, Dhouha Grissa, Charlotte Joly, Bernard Lyan, Eléonore Herquelot, Sébastien Czernichow, Marie Zins, Marcel Goldberg, Blandine Comte
The evolution of human health is a continuum of transitions, involving multifaceted processes at multiple levels and there is an urgent need for integrative biomarkers that can characterize and predict progression towards disease development. The objective of this work was to perform a systems metabolomics approach to predict metabolic syndrome (MetS) development. A case-control design was used within the French occupational GAZEL cohort (n=112 males: discovery study; n=94: replication/validation study). Our integrative strategy was to combine untargeted metabolomics with clinical, sociodemographic and food habit parameters to describe early phenotypes and build multidimensional predictive models...
April 25, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28439873/gender-development-in-transgender-preschool-children
#6
Anne A Fast, Kristina R Olson
An increasing number of transgender children-those who express a gender identity that is "opposite" their natal sex-are socially transitioning, or presenting as their gender identity in everyday life. This study asks whether these children differ from gender-typical peers on basic gender development tasks. Three- to 5-year-old socially transitioned transgender children (n = 36) did not differ from controls matched on age and expressed gender (n = 36), or siblings of transgender and gender nonconforming children (n = 24) on gender preference, behavior, and belief measures...
April 25, 2017: Child Development
https://www.readbyqxmd.com/read/28439741/effect-of-victimization-on-impulse-control-and-binge-drinking-among-serious-juvenile-offenders-from-adolescence-to-young-adulthood
#7
Jordan P Davis, Tara M Dumas, Benjamin L Berey, Gabriel J Merrin, Joseph R Cimpian, Brent W Roberts
A vast literature has found longitudinal effects of early life stress on substance use and self-regulatory processes. These associations may vary by period-specific development among youth involved in the juvenile justice system. The current study used an accelerated longitudinal design and auto-regressive latent trajectory with structure residuals (ALT-SR) model to examine the within-person cross-lagged associations between binge drinking, impulse control, and victimization from 15 to 25 years of age. A large sample (N = 1100) of justice-involved youth were followed longitudinally for 7 years (M age baseline  = 15...
April 24, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28439410/the-mental-health-of-unemployed-brussels-youth-the-role-of-social-and-material-resources
#8
Kelly Huegaerts, Vanessa Puig-Barrachina, Christophe Vanroelen
BACKGROUND: In the aftermath of the 2008 Great Recession, youth unemployment rates in the Brussels Capital Region (BCR) increased. The aim of this study is firstly to investigate the evolution of the mental health gap between employed and unemployed youth and secondly to examine the association of material and social resources with mental health of youth entering the labour market in the BCR. METHODS: Two data sources are used to answer the research questions: the Belgian Health Interview Survey (HIS) data (1997 to 2013; 18- to 29-year-olds; N = 5,562), and the authors' own primary data collection among Brussels youth in the transition from education to employment (2015; 18- to 29-year-olds; N = 1,151; BCR-sample)...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28439394/seasonal-variation-in-effects-of-herbivory-on-foliar-nitrogen-of-a-threatened-conifer
#9
Robert N Schaeffer, Nicole E Soltis, Jennifer L Martin, Aden L Brown, Sara Gómez, Evan L Preisser, Colin M Orians
Invasive herbivores can dramatically impact the nitrogen (N) economy of native hosts. In deciduous species, most N is stored in stem tissues, while in evergreen conifer species N is stored in needles, making them potentially more vulnerable to herbivory. In eastern forests of the USA, the long-lived, foundational conifer eastern hemlock (Tsuga canadensis) is under the threat of extirpation by the invasive hemlock woolly adelgid (HWA: Adelges tsugae). We assessed the impact of HWA infestation on the patterns of seasonal foliar N availability in hemlock planted in a deciduous forest understory...
March 2017: AoB Plants
https://www.readbyqxmd.com/read/28439357/resident-dyads-providing-transition-care-to-adolescents-and-young-adults-with-chronic-illnesses-and-neurodevelopmental-disabilities
#10
Richard J Chung, Joan Jasien, Gary R Maslow
BACKGROUND: Youth with special health care needs often experience difficulty transitioning from pediatric to adult care. These difficulties may derive in part from lack of physician training in transition care and the challenges health care providers experience establishing interdisciplinary partnerships to support these patients. OBJECTIVE: This educational innovation sought to improve pediatrics and adult medicine residents' interdisciplinary communication and collaboration...
April 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28439350/transgender-related-education-in-plastic-surgery-and-urology-residency-programs
#11
Shane D Morrison, Geolani W Dy, H Jonathan Chong, Sarah K Holt, Nicholas B Vedder, Mathew D Sorensen, Byron D Joyner, Jeffrey B Friedrich
BACKGROUND: With increasing public awareness of and greater coverage for gender-confirming surgery by insurers, more transgender patients are likely to seek surgical transition. The degree to which plastic surgery and urology trainees are prepared to treat transgender patients is unknown. OBJECTIVE: We assessed the number of hours dedicated to transgender-oriented education in plastic surgery and urology residencies, and the impact of program director (PD) attitudes on provision of such training...
April 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28439143/dynamics-of-urban-informal-labor-supply-in-the-united-states
#12
Samara R Gunter
OBJECTIVE: This study provides the first panel data estimates of informal work in the US and explores relationships between informal- and regular-sector participation among urban parents of young children. METHODS: I examine determinants of informal-sector participation in five waves of data from the Fragile Families and Child Wellbeing Study using probit, pooled Tobit, and fixed effects OLS models. RESULTS: Approximately 53 percent of urban fathers and 32 percent of urban mothers with young children pursue informal work over a nine-year period...
March 2017: Social Science Quarterly
https://www.readbyqxmd.com/read/28438820/use-of-an-argatroban-based-purge-solution-in-a-percutaneous-ventricular-assist-device
#13
Benjamin Laliberte, Brent N Reed
PURPOSE: The use of an argatroban-based percutaneous ventricular assist device (pVAD) purge solution in a patient with suspected heparin-induced thrombocytopenia (HIT) is described. SUMMARY: A 70-year-old woman in cardiogenic shock was admitted to a coronary care unit after being discovered unresponsive at home. A transthoracic echocardiogram revealed a low ejection fraction and findings consistent with takotsubo cardiomyopathy. Administration of multiple inotropes and vasopressors was initially required for hemodynamic support...
May 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28438467/the-role-of-impulsivity-in-psychostimulant-and-stress-induced-dopamine-release-review-of-human-imaging-studies
#14
REVIEW
Wendy M Bosker, Irene Neuner, N Jon Shah
Drug addiction is a debilitating disorder and its pivotal problem is the high relapse rate. To solve this problem, the aim is to prevent people from becoming addicted in the first place. One of the key questions that is still unanswered is why some people become addicted to drugs and others, who take drugs regularly, do not. In recent years extensive research has been done to untangle the many factors involved in this disorder. Here, we review some of the factors that are related to dopamine, i.e., impulsivity and stress (hormones), and aim to integrate this into a neurobiological model...
April 21, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28438246/does-dual-task-coordination-performance-decline-in-later-life
#15
María V Sebastián, Roberto Mediavilla
BACKGROUND: This cross-sectional study examined whether changes occur in people’s capacity to coordinate two simultaneous tasks (dual-task) when transitioning from adulthood to later life. The central executive, Baddeley’s working memory model component, is responsible for this coordination. Contradictory results have been reported regarding the relationship between ageing and dual-task performance; but these seem to be related to methodological issues that have been addressed in this study...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28438232/real-life-impact-of-executive-function-impairments-in-adults-who-were-born-very-preterm
#16
Jasmin Kroll, Vyacheslav Karolis, Philip J Brittain, Chieh-En Jane Tseng, Sean Froudist-Walsh, Robin M Murray, Chiara Nosarti
OBJECTIVES: Children and adolescents who were born very preterm (≤32 weeks' gestation) are vulnerable to experiencing cognitive problems, including in executive function. However, it remains to be established whether cognitive deficits are evident in adulthood and whether these exert a significant effect on an individual's real-lifeachievement. METHODS: Using a cross-sectional design, we tested a range of neurocognitive abilities, with a focus on executive function, in a sample of 122 very preterm individuals and 89 term-born controls born between 1979 and 1984...
April 25, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28438065/reduced-expression-of-eukaryotic-translation-initiation-factor-3-subunit-e-and-its-possible-involvement-in-the-epithelial-mesenchymal-transition-in-endometriosis
#17
Xianjun Cai, Minhong Shen, Xishi Liu, Sun-Wei Guo
Epithelial-mesenchymal transition (EMT) is now well documented to be involved in the development of endometriosis through the promotion of invasion and fibrogenesis. To date, several factors have been reported to be involved in EMT in endometriosis. The eukaryotic translation initiation factor 3 subunit e (eIF3e) protein is a component of the multisubunit eIF3 complex essential for cap-dependent translation initiation. The aim of this study was to investigate whether eIF3e is involved in EMT in endometriosis...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28437294/sleep-detriments-associated-with-quick-returns-in-rotating-shift-work-a-diary-study
#18
Øystein Vedaa, Erik Mørland, Marit Larsen, Anette Harris, Eilin Erevik, Børge Sivertsen, Bjørn Bjorvatn, Siri Waage, Ståle Pallesen
OBJECTIVE: We aimed to compared sleep characteristics associated with quick returns (QRs, <11 hours between shift intervals) with those associated with other common shift transitions. METHODS: Sixty-seven nurses completed a 2-week work and sleep diary (94.0% female, mean age 47.7 years). A multilevel fixed effects model was used to examine the sleep in QRs compared with two consecutive night shifts, two consecutive evening shifts, and two consecutive day shifts, respectively...
April 21, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28437219/factors-affecting-sexual-function-in-midlife-women-results-from-the-midlife-women-s-health-study
#19
Rebecca L Smith, Lisa Gallicchio, Jodi A Flaws
OBJECTIVE: The objective of this study was to estimate the importance of risk factors affecting sexual function in sexually active midlife women. MATERIALS AND METHODS: A cohort of 780 women undergoing the menopausal transition was surveyed each year for up to 7 years. Data were collected from sexually active women on sexual function, including frequencies of enjoyment, arousal, orgasm, passion for partner, satisfaction with partner, pain, lack of lubrication, fantasizing, and sexual activity...
February 28, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28436833/proactive-control-in-early-and-middle-childhood-an-erp-study
#20
Sarah Elke, Sandra A Wiebe
Children experience important cognitive control improvements in the transition to school. This study examined 4-5-year-olds' (n=17) and 7-8-year-olds' (n=22) ability to proactively deploy cognitive control. Children performed a cued task-switching paradigm presenting them with a cue indicating which attribute, color or shape, they should use to sort the upcoming stimulus. Following both cue and stimulus, we analyzed two event-related potentials: the P2 and P3, positive peaks reflecting sensory and attentional components of cognitive control, respectively...
April 14, 2017: Developmental Cognitive Neuroscience
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