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https://www.readbyqxmd.com/read/27914302/progressive-multi-atlas-label-fusion-by-dictionary-evolution
#1
Yantao Song, Guorong Wu, Khosro Bahrami, Quansen Sun, Dinggang Shen
Accurate segmentation of anatomical structures in medical images is important in recent imaging based studies. In the past years, multi-atlas patch-based label fusion methods have achieved a great success in medical image segmentation. In these methods, the appearance of each input image patch is first represented by an atlas patch dictionary (in the image domain), and then the latent label of the input image patch is predicted by applying the estimated representation coefficients to the corresponding anatomical labels of the atlas patches in the atlas label dictionary (in the label domain)...
November 24, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27914279/identification-and-quantification-of-4-methylethcathinone-4-mec-and-3-4-methylenedioxypyrovalerone-mdpv-in-hair-by-lc-ms-ms-after-chronic-administration
#2
Jean Claude Alvarez, Isabelle Etting, Emuri Abe, Antoine Villa, Nicolas Fabresse
4-Methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) are synthetic cathinones. The objective of this study was to develop a method in order to measure these compounds in hair of a patient. After decontamination, 20mg of hair were grinded and incubated in phosphate buffer pH 5.0 in presence of 100ng of MDMA-d5 used as internal standard. Double basic liquid-liquid extraction was performed. Samples were separated on a 1.9μm Hypersil GOLD PFP column (100×2.1mm) using gradient elution. Compounds were detected by a LCQ TSQ Vantage XP triple-quadrupole mass spectrometer...
November 24, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27913063/a-novel-approach-to-falls-classification-in-parkinson-s-disease-development-of-the-fall-related-activity-classification-frac
#3
Annie Ross, Alison J Yarnall, Lynn Rochester, Sue Lord
BACKGROUND: Falls are a major problem for people with Parkinson's disease (PD). Despite years of focused research knowledge of falls aetiology is poor. This may be partly due to classification approaches which conventionally report fall frequency. This nosology is blunt, and does not take into account causality or the circumstances in which the fall occurred. For example, it is likely that people who fall from a postural transition are phenotypically different to those who fall during high level activities...
September 3, 2016: Physiotherapy
https://www.readbyqxmd.com/read/27912026/how-mammalian-predation-contributes-to-tropical-tree-community-structure
#4
C E Timothy Paine, Harald Beck, John Terborgh
The recruitment of seedlings from seeds is the key demographic transition for rain forest trees. Though tropical forest mammals are known to consume many seeds, their effects on tree community structure remain little known. To evaluate their effects, we monitored 8,000 seeds of 24 tree species using exclosure cages that were selectively permeable to three size classes of mammals for up to 4.4 years. Small and medium-bodied mammals removed many more seeds than did large mammals, and they alone generated beta diversity and negative density dependence, whereas all mammals reduced diversity and shaped local species composition...
December 2016: Ecology
https://www.readbyqxmd.com/read/27911468/radical-cystectomy-and-cutaneous-ureterostomy-in-4-dogs-with-trigonal-transitional-cell-carcinoma-description-of-technique-and-case-series
#5
Rafael Ricardo Huppes, Leandro Z Crivellenti, Andrigo Barboza De Nardi, Bruno Roque Lima, Cristiane Alves Cintra, Jorge Luiz Costa Castro, Christopher A Adin
OBJECTIVE: To describe radical cystectomy followed by cutaneous ureterostomy as a treatment of invasive bladder neoplasia in dogs. STUDY DESIGN: Retrospective study. ANIMALS: Client-owned dogs with transitional cell carcinoma of the bladder trigone (n=4). METHODS: Perioperative complications and long-term outcomes of dogs that underwent cutaneous ureterostomy following radical cystectomy and lymphadenectomy for transitional cell carcinoma of the urinary bladder trigone were reviewed...
December 1, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27911422/-diagnostic-potential-of-optical-coherence-tomography-for-small-choroidal-melanomas
#6
A F Brovkina, A S Stoyukhina, I V Musatkina
AIM: To investigate the sequence of OCT manifestations in choroidal melanoma (CM) with account to its growth. MATERIAL AND METHODS: A total of 28 CM patients were examined. Of them, 18 patients with early CM, 10 - with medium-sized CM. The mean patient age at diagnosis was 60.54±5.31 years. Tumor location was macular (15 eyes) or perimacular (13 eyes), its prominence varied from 0.98 to 4.9 mm and basal diameter - from 5.08 to 18.9 mm. Additionally to OCT, tumor autofluorescence was studied in all cases...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27910708/myo-inositol-and-melatonin-in-the-menopausal-transition
#7
Rosario D'Anna, Angelo Santamaria, Grazia Giorgianni, Alberto Vaiarelli, Giuseppe Gullo, Flavia Di Bari, Salvatore Benvenga
INTRODUCTION: The aim of the study was to evaluate the effects on serum insulin and serum thyroid profile of a dietary supplement, myo-inositol, given alone or in combination with melatonin to women during menopausal transition. METHODS: Forty women aged 45-55 years and at least 6 months of amenorrhea were enrolled in this study. They were randomly assigned to two groups of 20 each. One group took myo-inositol (myo-Ins) (2 g twice a day) and the other group took 2 g/d myo-Ins plus 3 g/d melatonin before sleeping...
December 2, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27910116/the-cost-effectiveness-of-testing-for-ns5a-resistance-associated-polymorphisms-at-baseline-in-genotype-1a-infected-treatment-na%C3%A3-ve-and-treatment-experienced-subjects-treated-with-all-oral-elbasvir-grazoprevir-regimens-in-the-united-states
#8
E H Elbasha, M N Robertson, C Nwankwo
BACKGROUND: The presence of baseline NS5A resistance-associated variants (RAVs) impacted treatment response in HCV genotype 1a (GT1a)-infected patients treated with elbasvir/grazoprevir (EBR/GZR) for 12 weeks, but not patients treated with EBR/GZR and ribavirin (RBV) for 16 weeks. AIM: We assessed the cost-effectiveness of baseline testing for NS5A RAVs in EBR/GZR-treated patients compared without testing and with current treatments for GT1a patients. METHODS: We simulated the course of treatment with EBR/GZR, ledipasvir/sofosbuvir (LDV/SOF) and ombitasvir/paritaprevir/ritonavir+dasabuvir (3D) with or without RBV and natural history of disease of GT1a patients...
December 1, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27909585/developmental-idealism-body-weight-and-shape-and-marriage-entry-in-transitional-china
#9
Hongwei Xu
New trends toward later and less marriage are emerging in post-reform China. Previous research has examined the changing individual-level socioeconomic and demographic characteristics shaping marriage entry in Chinese adults. Employing a cultural model known as developmental idealism (DI), this study argues that a new worldview specifying an ideal body type has become popular in the West and that this new worldview has been exported to China. This new part of the DI package is likely stratified by gender, has a stronger impact on women than on men, and has likely penetrated urban areas more than rural areas...
April 2016: Chinese Journal of Sociology
https://www.readbyqxmd.com/read/27909366/standing-on-the-precipice-evaluating-final-year-physiotherapy-students-perspectives-of-their-curriculum-as-preparation-for-primary-health-care-practice
#10
Sinead McMahon, Grainne O'Donoghue, Catherine Doody, Geraldine O'Neill, Terry Barrett, Tara Cusack
Purpose: To explore final-year physiotherapy students' perceptions of primary health care practice to determine (1) aspects of their curriculum that support their learning, (2) deficiencies in their curriculum, and (3) areas that they believe should be changed to adequately equip them to make the transition from student to primary health care professional. Methods: Framework analysis methodology was used to analyze group opinion obtained using structured group feedback sessions. Sixty-eight final-year physiotherapy students from the four higher education institutions in Ireland participated...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27909000/distinct-contributions-of-dorsal-and-ventral-streams-to-imitation-of-tool-use-and-communicative-gestures
#11
Andrea Dressing, Kai Nitschke, Dorothee Kümmerer, Tobias Bormann, Lena Beume, Charlotte S M Schmidt, Vera M Ludwig, Irina Mader, Klaus Willmes, Michel Rijntjes, Christoph P Kaller, Cornelius Weiller, Markus Martin
Imitation of tool-use gestures (transitive; e.g., hammering) and communicative emblems (intransitive; e.g., waving goodbye) is frequently impaired after left-hemispheric lesions. We aimed 1) to identify lesions related to deficient transitive or intransitive gestures, 2) to delineate regions associated with distinct error types (e.g., hand configuration, kinematics), and 3) to compare imitation to previous data on pantomimed and actual tool use. Of note, 156 patients (64.3 ± 14.6 years; 56 female) with first-ever left-hemispheric ischemic stroke were prospectively examined 4...
November 30, 2016: Cerebral Cortex
https://www.readbyqxmd.com/read/27907264/the-legacy-of-large-regime-shifts-in-shallow-lakes
#12
Joy M Ramstack Hobbs, William O Hobbs, Mark B Edlund, Kyle D Zimmer, Kevin M Theissen, Natalie Hoidal, Leah M Domine, Mark A Hanson, Brian R Herwig, James B Cotner
Ecological shifts in shallow lakes from clear-water macrophyte-dominated to turbid-water phytoplankton-dominated are generally thought of as rapid short-term transitions. Diatom remains in sediment records from shallow lakes in the Prairie Pothole Region of North America provide new evidence that the long-term ecological stability of these lakes is defined by the legacy of large regime shifts. We examine the modern and historical stability of 11 shallow lakes. Currently, four of the lakes are in a clear-water state, three are consistently turbid-water, and four have been observed to change state from year to year (transitional)...
December 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/27907261/fitting-state-space-integral-projection-models-to-size-structured-time-series-data-to-estimate-unknown-parameters
#13
J Wilson White, Kerry J Nickols, Daniel Malone, Mark H Carr, Richard M Starr, Flora Cordoleani, Marissa L Baskett, Alan Hastings, Louis W Botsford
Integral projection models (IPMs) have a number of advantages over matrix-model approaches for analyzing size-structured population dynamics, because the latter require parameter estimates for each age or stage transition. However, IPMs still require appropriate data. Typically they are parameterized using individual-scale relationships between body size and demographic rates, but these are not always available. We present an alternative approach for estimating demographic parameters from time series of size-structured survey data using a Bayesian state-space IPM (SSIPM)...
December 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/27907223/-mental-retirement-trajectories-of-work-engagement-preceding-retirement-among-older-workers
#14
Astrid de Wind, Fenna Rm Leijten, Trynke Hoekstra, Goedele A Geuskens, Alex Burdorf, Allard J van der Beek
Objectives Before actual retirement, employees may already distance themselves from work, which could be referred to as "mental retirement". However, trajectories of work motivation, ie, work engagement, have not been studied yet. The present study aimed to (i) identify different trajectories of work engagement among older workers approaching the retirement age, and (ii) examine their associations with actual retirement. Methods In total 3171 employees aged 55-62 years, who participated in the Dutch Study on Transitions in Employment, Ability and Motivation were included in this study...
December 1, 2016: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/27906313/experimental-study-on-the-transition-of-plasmonic-resonance-modes-in-double-ring-dimers-by-conductive-junctions-in-the-terahertz-regime
#15
Huifang Zhang, Chun Li, Caihong Zhang, Xueqian Zhang, Jianqiang Gu, Biaobing Jin, Jiaguang Han, Weili Zhang
Plasmonic dimers that made from two subwavelength particles have drawn much attention in the recent years, which are quite promising in local field enhancement, sensing, high frequency conductance probing and electron tunneling. In this work, we experimentally investigate the mode transition effect of different plasmonic resonances in double-ring dimers when introducing conductive junction at the dimer gap in the terahertz regime. Without the junction, the dimers support a single dipolar bonding dimer plasmonic (BDP) mode...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906029/trends-in-clinical-characteristics-and-outcomes-of-pre-art-care-at-a-large-hiv-clinic-in-nairobi-kenya-a-retrospective-cohort-study
#16
Jared O Mecha, Elizabeth N Kubo, Lucy W Nganga, Peter N Muiruri, Lilian N Njagi, Immaculate N Mutisya, Justine J Odionyi, Syokau C Ilovi, Mary Wambui, Christopher Githu, Richard Ngethe, Elizabeth M Obimbo, Zipporah W Ngumi
BACKGROUND: The success of antiretroviral therapy in resource-scarce settings is an illustration that complex healthcare interventions can be successfully delivered even in fragile health systems. Documenting the success factors in the scale-up of HIV care and treatment in resource constrained settings will enable health systems to prepare for changing population health needs. This study describes changing demographic and clinical characteristics of adult pre-ART cohorts, and identifies predictors of pre-ART attrition at a large urban HIV clinic in Nairobi, Kenya...
November 14, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905981/correlates-of-meal-skipping-in-young-adults-a-systematic-review
#17
REVIEW
Felicity J Pendergast, Katherine M Livingstone, Anthony Worsley, Sarah A McNaughton
BACKGROUND: Meal skipping rates may be highest during young adulthood, a period of transition and development. Although these dietary behaviours may increase future risk of chronic disease, limited research has investigated correlates of meal skipping in young adults. METHODS: A systematic literature search was conducted to identify studies that investigated correlates of meal skipping behaviours in young adults (aged 18-30 years). EBSCO host, MEDLINE Complete, Global Health, Scopus, EMBASE, Web of Science and Informit platforms were searched for eligible articles...
December 1, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27905955/future-healthy-life-expectancy-among-older-adults-in-the-us-a-forecast-based-on-cohort-smoking-and-obesity-history
#18
Bochen Cao
BACKGROUND: In the past three decades, the elderly population in the United States experienced increase in life expectancy (LE) and disability-free life expectancy (LE(ND)), but decrease in life expectancy with disability (LE(D)). Smoking and obesity are two major risk factors that had negative impacts on these trends. While smoking prevalence continues to decline in recent decades, obesity prevalence has been growing and is currently at a high level. This study aims to forecast the healthy life expectancy for older adults aged 55 to 85 in the US from 2011 to 2040, in relation to their smoking and obesity history...
July 12, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905948/changes-in-life-expectancy-1950-2010-contributions-from-age-and-disease-specific-mortality-in-selected-countries
#19
Jochen Klenk, Ulrich Keil, Andrea Jaensch, Marcus C Christiansen, Gabriele Nagel
BACKGROUND: Changes of life expectancy over time serve as an interesting public health indicator for medical, social and economic developments within populations. The aim of this study was to quantify changes of life expectancy between 1950 and 2010 and relate these to main causes of death. METHODS: Pollard's actuarial method of decomposing life expectancy was applied to compare the contributions of different age- and disease-groups on life expectancy in 5-year intervals...
May 23, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905943/social-patterns-and-differentials-in-the-fertility-transition-in-the-context-of-hiv-aids-evidence-from-population-surveillance-rural-south-africa-1993-2013
#20
Brian Houle, Athena Pantazis, Chodziwadziwa Kabudula, Stephen Tollman, Samuel J Clark
BACKGROUND: Literature is limited on the effects of high prevalence HIV on fertility in the absence of treatment, and the effects of the introduction of sustained access to antiretroviral therapy (ART) on fertility. We summarize fertility patterns in rural northeast South Africa over 21 years during dynamic social and epidemiological change. METHODS: We use data for females aged 15-49 from the Agincourt health and socio-demographic surveillance system (1993-2013)...
March 25, 2016: Population Health Metrics
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