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https://www.readbyqxmd.com/read/28620023/synthetic-biology-engineering-of-biofilms-as-nanomaterials-factories
#1
REVIEW
Peter Q Nguyen
Bottom-up fabrication of nanoscale materials has been a significant focus in materials science for expanding our technological frontiers. This assembly concept, however, is old news to biology - all living organisms fabricate themselves using bottom-up principles through a vast self-organizing system of incredibly complex biomolecules, a marvelous dynamic that we are still attempting to unravel. Can we use what we have gleaned from biology thus far to illuminate alternative strategies for designer nanomaterial manufacturing? In the present review article, new synthetic biology efforts toward using bacterial biofilms as platforms for the synthesis and secretion of programmable nanomaterials are described...
June 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28595994/-news-techniques-of-pacing-in-congenital-heart-diseases
#2
Mathieu Le Bloa, Jean-Benoît Thambo
The number of children and adult with congenital heart disease requiring implantation of cardiac pacemaker or cardioverter defibrillator is constantly increasing. The lead between stimulation/defibrillation site and the generator constitutes the main weakpoint of those devices despite the numerous recent technological advances: use of bipolar probes, corticoid elution electrodes, insulation improvement, magnetic resonance imaging (MRI) compatibility. Risk of device failure remains high in this population. Long term adverse events with endovascular devices remain high...
June 5, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28590895/a-qualitative-case-study-of-smartphone-connected-hearing-aids-influences-on-patients-clinicians-and-patient-clinician-interactions
#3
Stella L Ng, Shanon Phelan, MaryAnn Leonard, Jason Galster
BACKGROUND: Innovations in hearing aid technology influence clinicians and individuals who use hearing aids. Little research, to date, explains the innovation adoption experiences and perspectives of clinicians and patients, which matter to a field like audiology, wherein technology innovation is constant. By understanding clinician and patient experiences with such innovations, the field of audiology may develop technologies and ways of practicing in a manner more responsive to patients' needs, and attentive to society's influence...
June 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28566099/health-technology-assessment-the-scientific-career-of-a-policy-concept
#4
Cyril Benoit, Philippe Gorry
OBJECTIVES: The aim of this work was to provide a comprehensive overview of the evolution of the health technology assessment (HTA) concept in the scientific literature through a scientometric approach. METHODS: A literature search was conducted, by selecting publications, as well as news from the media, containing "health technology assessment" in their title, abstracts, or keywords. We then undertook a bibliometric and network analysis on the corpus of 2,865 publications thus obtained...
June 1, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28526922/advances-in-systemic-therapy-for-metastatic-breast-cancer-future-perspectives
#5
REVIEW
S P Corona, N Sobhani, A Ianza, G Roviello, G Mustacchi, M Bortul, F Zanconati, D Generali
Breast cancer (BC) is the most common cancer in women worldwide. One in eight women will develop the disease in her lifetime. Notwithstanding the incredible progress made in this field, BC still represents the second most common cause of cancer-related death in women. Targeted drugs have revolutionised breast cancer treatment and improved the prognosis as well as the life expectancy of millions of women. However, the phenomenon of primary and secondary pharmacological resistance is becoming increasingly evident, limiting the efficacy of these agents and calling for a better in-depth knowledge and understanding of the biology as well as the biochemical crosstalk underlying the disease...
July 2017: Medical Oncology
https://www.readbyqxmd.com/read/28511767/finding-the-virtue-in-virtual-care
#6
Zachary Hafner
It's going to take a lot of work. The good news is that great progress is already being made. As technology and consumer expectations continue to evolve, we can expect virtual care to play an increasingly important role in ushering in truly integrated care.
April 2017: Managed Care
https://www.readbyqxmd.com/read/28493015/u-s-news-media-coverage-of-pharmaceutical-pollution-in-the-aquatic-environment-a-content-analysis-of-the-problems-and-solutions-presented-by-actors
#7
Benjamin Blair, Daniel Zimny-Schmitt, Murray A Rudd
Pharmaceutical pollution in the aquatic environment is an issue of concern that has attracted attention by the news media. Understanding the factors that contribute to media framing of pharmaceutical pollution may lead to a better understanding of the management and governance of this issue, including why these pollutants are generally unregulated at this time. This study conducted a content analysis of 405 newspaper articles (81 had substantive information on the topic) from 2007 to 2014, using the search terms "water" and "pharmaceuticals" in the Chicago Tribune, Denver Post, Los Angeles Times, New York Daily News, New York Times, USA Today, Wall Street Journal, and Washington Post...
May 10, 2017: Environmental Management
https://www.readbyqxmd.com/read/28396304/comparing-crowdsourcing-and-friendsourcing-a-social-media-based-feasibility-study-to-support-alzheimer-disease-caregivers
#8
Daniel Robert Bateman, Erin Brady, David Wilkerson, Eun-Hye Yi, Yamini Karanam, Christopher M Callahan
BACKGROUND: In the United States, over 15 million informal caregivers provide unpaid care to people with Alzheimer disease (AD). Compared with others in their age group, AD caregivers have higher rates of stress, and medical and psychiatric illnesses. Psychosocial interventions improve the health of caregivers. However, constraints of time, distance, and availability inhibit the use of these services. Newer online technologies, such as social media, online groups, friendsourcing, and crowdsourcing, present alternative methods of delivering support...
April 10, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28371156/materials-devices-and-systems-of-soft-bioelectronics-for-precision-therapy
#9
REVIEW
Hao Wu, Wei Gao, Zhouping Yin
The potential applications of soft bioelectronics in biomedical research and clinical trials have inspired a great deal of research interest in the past decade. While there has been significant amount of work in the fabrication and characterization of soft and stretchable sensors for monitoring of physical conditions and vital signs of human body, the development of soft bioelectronics based medical treatment and intervention systems has just begun. In addition to health monitoring, active treatments are essential for disease control in the healthcare domain, and medical therapy and surgery realized by sophisticated soft bioelectronic systems are better demonstrations of their utility in healthcare...
May 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28370445/media-hype-patient-and-scientific-perspectives-on-misleading-medical-news
#10
Israel Robledo, Joseph Jankovic
In this age of digital technology, Internet, and social media we are increasingly subjected to an information and disinformation overload. This includes not only political and economic information but also medical news, which is often presented as a "new discovery", "miracle cure" or some other press hyperbole. In this viewpoint article we present patient and scientific perspectives some recent episodes of medical hype related to Parkinson's disease research, including proposed therapies such as nilotinib, marijuana, stem cells and other controversial therapies that have attracted the mainstream and social media...
April 3, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28353352/detecting-changes-in-newspaper-reporting-of-suicide-after-a-statewide-social-marketing-campaign
#11
Michele Abbott, Rajeev Ramchand, Margaret Chamberlin, William Marcellino
A social marketing campaign was introduced in California in 2012, promoting media adherence to consensus-based guidelines on reporting about suicide. We examine adherence to these guidelines by applying quantitative scores to articles in California and a national control group in two six-month intervals prior to and following campaign implementation. Utilizing a difference-in-difference approach, we found no significant effect of the campaign, though the type of article content was a significant indicator of the overall score...
March 29, 2017: Health Communication
https://www.readbyqxmd.com/read/28347443/digital-disease-detection-a-systematic-review-of-event-based-internet-biosurveillance-systems
#12
Jesse O'Shea
BACKGROUND: Internet access and usage has changed how people seek and report health information. Meanwhile,infectious diseases continue to threaten humanity. The analysis of Big Data, or vast digital data, presents an opportunity to improve disease surveillance and epidemic intelligence. Epidemic intelligence contains two components: indicator based and event-based. A relatively new surveillance type has emerged called event-based Internet biosurveillance systems. These systems use information on events impacting health from Internet sources, such as social media or news aggregates...
May 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28088881/an-industry-update-the-latest-developments-in-therapeutic-delivery
#13
Iain Simpson
This Industry Update covers the period from 1 October through to 31 October 2016, and is based on information sourced from company press releases, scientific literature, patents and various news websites. The month saw several news items covering drug-delivery devices, including a new sensor to monitor and support the use of inhalers; launch in the UK of a new autoinjector for Cimzia(®), UCB's rheumatoid arthritis drug; and approval of Roche's Lucentis(®) in a prefilled syringe. Research was also published to show the value of continuous blood pressure monitoring in dementia management...
February 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28077490/improving-uniformity-in-brain-death-determination-policies-over-time
#14
Hilary H Wang, Panayiotis N Varelas, Galen V Henderson, Eelco F M Wijdicks, David M Greer
OBJECTIVE: To demonstrate that progress has been made in unifying brain death determination guidelines in the last decade by directly comparing the policies of the US News and World Report's top 50 ranked neurologic institutions from 2006 and 2015. METHODS: We solicited official hospital guidelines in 2015 from these top 50 institutions, generated summary statistics of their criteria as benchmarked against the American Academy of Neurology Practice Parameters (AANPP) and the comparison 2006 cohort in 5 key categories, and statistically compared the 2 cohorts' compliance with the AANPP...
February 7, 2017: Neurology
https://www.readbyqxmd.com/read/28035492/factors-influencing-the-use-of-a-mobile-app-for-reporting-adverse-drug-reactions-and-receiving-safety-information-a-qualitative-study
#15
Sieta T de Vries, Lisa Wong, Alastair Sutcliffe, François Houÿez, Carmen Lasheras Ruiz, Peter G M Mol
INTRODUCTION: A mobile app may increase the reporting of adverse drug reactions (ADRs) and improve the communication of new drug safety information. Factors that influence the use of an app for such two-way risk communication need to be considered at the development stage. OBJECTIVE: Our aim was to reveal the factors that may influence healthcare professionals (HCPs) and patients to use an app for two-way risk communication. METHODS: Focus group discussions and face-to-face interviews were conducted in the Netherlands, Spain and the UK...
May 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27932913/lifewatchgreece-portal-development-architecture-implementation-and-challenges-for-a-biodiversity-research-e-infrastructure
#16
Alexandros Gougousis, Nicolas Bailly
BACKGROUND: Biodiversity data is characterized by its cross-disciplinary character, the extremely broad range of data types and structures, and the plethora of different data sources providing resources for the same piece of information in a heterogeneous way. Since the web inception two decades ago, there are multiple initiatives to connect, aggregate, share, and publish biodiversity data, and to establish data and work flows in order to analyze them. The European program LifeWatch aims at establishing a distributed network of nodes implementing virtual research environment in Europe to facilitate the work of biodiversity researchers and managers...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27806923/it-s-time-for-innovation-in-the-health-insurance-portability-and-accountability-act-hipaa
#17
Karen Colorafi, Bryan Bailey
Whether it is the result of a tragic news story, a thoughtful commentary, or a segment on the entertainment networks, patient privacy rights are never far from the top of our minds. The Privacy and Security Rules contained in the Health Insurance Portability and Accountability Act of 1996 (HIPAA) represent a concerted effort to protect the privacy and security of the volumes of patient data generated by the health care system. However, the last twenty years has seen innovations and advancements in health information technology that were unimaginable at that time...
November 2, 2016: JMIR Medical Informatics
https://www.readbyqxmd.com/read/27778227/high-tech-or-high-risk-an-analysis-of-media-reports-about-robotic-surgery
#18
Zita Ficko, Kevin Koo, Elias S Hyams
Robotic surgery continues to increase in popularity and prevalence. The adoption of robotic technology has generated controversy and frequent media coverage. We evaluate recent reports of surgical robotics in the lay press to characterize its objectivity. LexisNexis and Factiva consumer news databases were queried for articles pertaining to robotic surgery published during 2010-2015 in the three highest circulation national (US) newspapers as well as New England regional newspapers. Two independent reviewers performed content analysis and assessed headline bias with strong reliability (mean κ = 0...
October 24, 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/27714472/function-preserving-gastrectomy-based-on-the-sentinel-node-concept-in-early-gastric-cancer
#19
REVIEW
Hiroya Takeuchi, Osamu Goto, Naohisa Yahagi, Yuko Kitagawa
Recent meta-analyses and a prospective multicenter trial of sentinel node (SN) mapping in early gastric cancer have demonstrated acceptable SN detection rates and accuracy of determination of lymph node status. SN mapping may play a key role in obtaining individual metastatic information. It also allows modification of surgical procedures, including function-preserving gastrectomy in patients with early gastric cancer. A dual-tracer method that uses radioactive colloids and blue dye is currently considered the most reliable method for the stable detection of SNs in patients with early gastric cancer...
March 2017: Gastric Cancer
https://www.readbyqxmd.com/read/27698665/evaluation-and-verification-of-the-global-rapid-identification-of-threats-system-for-infectious-diseases-in-textual-data-sources
#20
Andrew G Huff, Nathan Breit, Toph Allen, Karissa Whiting, Christopher Kiley
The Global Rapid Identification of Threats System (GRITS) is a biosurveillance application that enables infectious disease analysts to monitor nontraditional information sources (e.g., social media, online news outlets, ProMED-mail reports, and blogs) for infectious disease threats. GRITS analyzes these textual data sources by identifying, extracting, and succinctly visualizing epidemiologic information and suggests potentially associated infectious diseases. This manuscript evaluates and verifies the diagnoses that GRITS performs and discusses novel aspects of the software package...
2016: Interdisciplinary Perspectives on Infectious Diseases
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