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Nabil Mokrani, Philippe Gillard
This paper presents a physical and statistical approach to laser-induced breakdown in n-decane/N2  + O2 mixtures as a function of incident or absorbed energy. A parametric study, with pressure, fuel purity and equivalence ratio, was conducted to determine the incident and absorbed energies involved in producing breakdown, followed or not by ignition. The experiments were performed using a Q-switched Nd-YAG laser (1064 nm) inside a cylindrical 1-l combustion chamber in the range of 1-100 mJ of incident energy...
March 26, 2018: Journal of Hazardous Materials
Jennifer B Ganz, Kevin M Ayres
Single-case experimental designs (SCEDs), or small-n experimental research, are frequently implemented to assess approaches to improving outcomes for people with disabilities, particularly those with low-incidence disabilities, such as some developmental disabilities. SCED has become increasingly accepted as a research design. As this literature base is needed to determine what interventions are evidence-based practices, the acceptance of SCED has resulted in increased critiques with regard to methodological quality...
April 12, 2018: Research in Developmental Disabilities
Kai-Yang Leong, Feng Wang
The surface tension of nanoscale droplets of water was studied with molecular dynamics simulations using the BLYPSP-4F water potential. The internal pressure of the droplet was measured using an empirical correlation between the pressure and density, established through a series of bulk simulations performed at pressures from 1 to 1000 bars. Such a procedure allows for reliable determination of internal pressure without the need to calculate the local virial. The surface tension, estimated with the Young-Laplace relation, shows good agreement with the Tolman equation with a Tolman length of -0...
April 14, 2018: Journal of Chemical Physics
Yuebian Zhang, Wenwei Liu, Zhancheng Li, Zhi Li, Hua Cheng, Shuqi Chen, Jianguo Tian
We design and numerically analyze a high-quality (Q)-factor, high modulation depth, multiple Fano resonance device based on periodical asymmetric paired bars in the near-infrared regime. There are four sharp Fano peaks arising from the interference between subradiant modes and the magnetic dipole resonance mode that can be easily tailored by adjusting different geometric parameters. The maximal Q-factor can exceed 105 in magnitude, and the modulation depths ΔT can reach nearly 100%. Combining the narrow resonance line-widths with strong near-field confinement, we demonstrate an optical refractive index sensor with a sensitivity of 370 nm/RIU and a figure of merit of 2846...
April 15, 2018: Optics Letters
Prabhat Suman, Sarthak Mishra, Harish Chander
Metastatic spread of the cancer is usually the consequence of the activation of signaling pathways that generate cell motility and tissue invasion. Metastasis involves the reorganization of cytoskeleton and cell shape for the swift movement of the cells through extracellular matrix. Previously, we have described the invasive and metastatic role played by one of the members (Toca-1) of CIP4 subfamily of F-BAR proteins. In the present study, we address the role of another member (FBP17) of same family in the invasion breast cancer cells...
April 12, 2018: Medical Oncology
Francesco Passamonti, Margherita Maffioli
Myeloproliferative neoplasms (MPNs) include essential thrombocythemia, polycythemia vera (PV) and primary myelofibrosis (PMF). Phenotype-driver mutations of JAK2, CALR and MPL genes are present in MPNs and can be variably combined with additional mutations. Driver mutations entail a constitutive activation of the JAK2/STAT pathway, the key signaling cascade in MPNs. Among JAK2 inhibitors (JAKis), ruxolitinib (RUX) has been approved for the treatment of intermediate and high risk myelofibrosis (MF) and of PV inadequately controlled by or intolerant of hydroxyurea...
April 12, 2018: Blood
Xuezi Yao, Zhen Zhou, Man He, Beibei Chen, Yong Liang, Bin Hu
In this work, poly(1-vinylimidazole-ethyleneglycol dimethacrylate) (poly(VI-EDMA)) monolith coated stir bars were synthesized by one-pot polymerization, and they exhibited higher extraction efficiency and faster extraction dynamics for selected PFAAs than commercial ethylene glycol modified silicone (EG-silicone) and polydimethylsiloxane (PDMS) coated stir bars. Taking eleven PFAAs as target analytes, including C4-C12 perfluoroalkyl carboxylates (PFCAs) and C6, C8 perfluoroalkane sulfonates (PFSAs), a method combining monolith-based stir bar sorptive extraction (SBSE) with high performance liquid chromatography (HPLC) - electrospray tandem mass spectrometry (ESI-MS/MS) was proposed for the determination of multiplex PFAAs in environmental water samples...
April 6, 2018: Journal of Chromatography. A
Emmanuel Kamba Mebourou, Balázs Bernáth, Dominique Schenker, Patrick M Guerin
Organisms respond to environmental stimuli in ways that optimize survival and reproduction. Tsetse fly life-history is characterized by high investment in progeny by the pregnant female and low birth rate. This places constraints on tsetse populations across the sub-Saharan biotopes they colonize where extreme climatic conditions militate against survival. Controlling metabolic rate is crucial in biotopes where daily swings in temperature can exceed 20 o C. Tsetse acquire their nutrient requirements from the blood meal...
April 9, 2018: Journal of Insect Physiology
Yael S Rodger, Gili Greenbaum, Micha Silver, Shirli Bar-David, Gidon Winters
Genetic diversity and structure of populations at the edge of the species' spatial distribution are important for potential adaptation to environmental changes and consequently, for the long-term survival of the species. Here, we combined classical population genetic methods with newly developed network analyses to gain complementary insights into the genetic structure and diversity of Acacia tortilis, a keystone desert tree, at the northern edge of its global distribution, where the population is under threat from climatic, ecological, and anthropogenic changes...
2018: PloS One
Yvonne C DePorre, James R Annand, Sukanta Bar, Corinna S Schindler
A synthetic method for the efficient construction of β-hydroxylactones and lactams bearing α-quaternary carbon centers is described. This transformation relies on an electronically differentiated Lewis base catalyst, which is uniquely capable of promoting a reductive aldol reaction of α,α-disubstituted and α,α,β-trisubstituted enones. This approach provides a valuable synthetic alternative for carbon-carbon bond formation in complex molecular settings due to its orthogonal reactivity compared to that of traditional aldol reactions...
April 12, 2018: Organic Letters
Will J R Stone, Joseph J Campo, André Lin Ouédraogo, Lisette Meerstein-Kessel, Isabelle Morlais, Dari Da, Anna Cohuet, Sandrine Nsango, Colin J Sutherland, Marga van de Vegte-Bolmer, Rianne Siebelink-Stoter, Geert-Jan van Gemert, Wouter Graumans, Kjerstin Lanke, Adam D Shandling, Jozelyn V Pablo, Andy A Teng, Sophie Jones, Roos M de Jong, Amanda Fabra-García, John Bradley, Will Roeffen, Edwin Lasonder, Giuliana Gremo, Evelin Schwarzer, Chris J Janse, Susheel K Singh, Michael Theisen, Phil Felgner, Matthias Marti, Chris Drakeley, Robert Sauerwein, Teun Bousema, Matthijs M Jore
The original version of this Article contained errors in Fig. 3. In panel a, bars from a chart depicting the percentage of antibody-positive individuals in non-infectious and infectious groups were inadvertently included in place of bars depicting the percentage of infectious individuals, as described in the Article and figure legend. However, the p values reported in the Figure and the resulting conclusions were based on the correct dataset. The corrected Fig. 3a now shows the percentage of infectious individuals in antibody-negative and -positive groups, in both the PDF and HTML versions of the Article...
April 11, 2018: Nature Communications
Jinny Ha, Robert A Sikorski, James V O'Connor
No abstract text is available yet for this article.
January 1, 2018: American Surgeon
Zlatko Matjačić, Matjaž Zadravec, Andrej Olenšek
BACKGROUND: For stroke survivors, balance deficits that persist after the completion of the rehabilitation process lead to a significant risk of falls. We have recently developed a balance-assessment robot (BAR-TM) that enables assessment of balancing abilities during walking. The purpose of this study was to test feasibility of using the BAR-TM in an experimental perturbed-balance training program with a selected high-functioning stroke survivor. METHODS: A control and an individual with right-side chronic hemiparesis post-stroke were studied...
April 11, 2018: Journal of Neuroengineering and Rehabilitation
Taki Karsli, Murat Soner Balcioglu
Objective: The first stage in both breeding and programmes for the conservation of genetic resources are the identification of genetic diversity in the relevant population. The aim of the present study is to identify genetic diversity of six brown layer pure chicken lines (Rhode Island Red (RIRI, RIRII), Barred Rock (BARI, BARII), Columbian Rock (COL) and Line 54 (L-54)) with microsatellite markers. Furthermore, the study aims to employ its findings to discuss the possibilities for the conservation and sustainable use of these lines that have been bred as closed populations for a long period of time...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
Shimi Barda, Tomer Bar-Noy, Amnon Botchan, Ofer Lehavi, Haim Yavetz, Ron Hauser
BACKGROUND: Male infertility is solely responsible for approximately 20% of all infertility in couples. Various factors have been proposed as having a negative effect on sperm quality; however, the reasons for the global decline in sperm parameters during the last few decades are still controversial. OBJECTIVES: To investigate the fluctuations of semen parameters (sperm concentration, motility, and morphology) in three sperm quality groups and to examine the trends of those parameters in the same men over time...
April 2018: Israel Medical Association Journal: IMAJ
Ilya V Novikov, Marina A Pigaleva, Sergei S Abramchuk, Vyacheslav S Molchanov, Olga E Philippova, Marat O Gallyamov
Chitosan-based hydrogels with stabilized Ag nanoparticles were synthesized in the aqueous solutions of carbonic acid, i.e. water saturated with CO2 under pressure in hundreds of bars. Such a medium is biocompatible and self-neutralizing at decompression. The influence of various parameters, such as chitosan molecular weight, molar ratio of chitosan to silver, additional stabilization of gels by genipin as a cross-linking agent, on the structure of the chitosan/Ag composites was investigated using transmission electron microscopy, scanning electron microscopy, X-ray diffraction analysis, rheology measurements...
June 15, 2018: Carbohydrate Polymers
Ji-Hye Seo, Mukul Sharma, Erich Osterberg, Brian P Jackson
Here we use two chemical separation procedures to determine exceptionally low Os concentrations (~10-15 g g-1) and Os isotopic composition in polar snow/ice. Melt water weighing approximately 50 g is spiked with 190Os tracer solution and frozen at -20 °C in quartz-glass ampoules. A mixture of H2O2 and HNO3 is then added and the sample is heated to 300 °C at 100 bar using a High Pressure Asher. This allows tracer Os to be equilibrated with the sample as all Os species are oxidized to OsO4. The resulting OsO4 is extracted using either distillation (Method-I) or solvent-extraction (Method-II), purified, and measured using negative thermal ionization mass spectrometry (N-TIMS)...
April 8, 2018: Analytical Chemistry
Alexandre P Sater, Leonard T Rael, Allen H Tanner, Mark J Lieser, David L Acuna, Charles W Mains, David Bar-Or
Within the first few hours of a traumatic brain injury, the activity of extracellular matrix degradative enzymes increases. As a result, the blood brain barrier becomes disrupted as secondary white matter injury increases. Anoikis, a form of apoptosis, results from cells detaching from the extracellular matrix leading to cell death. This "homelessness" (anoikis) of cells hinders recovery progression, exacerbating brain injury while disrupting synaptic plasticity and other central nervous system functions...
April 5, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
Robert J Obermeyer, Nina S Cohen, Sheema Gaffar, Robert E Kelly, M Ann Kuhn, Frazier W Frantz, Margaret M McGuire, James F Paulson
BACKGROUND/PURPOSE: Our previously published data suggested several risk factors for infection after the Nuss procedure. We aimed to further elucidate these findings. METHODS: An IRB-approved (14-03-WC-0034), single institution, retrospective review was performed to evaluate the incidence of postoperative Nuss bar infections associated with seven variables. These were subjected to bivariate and multivariable analyses. A broad definition of infection was used including cellulitis, superficial infection with drainage, or deep infection occurring at any time postoperatively...
March 8, 2018: Journal of Pediatric Surgery
Bar Cohn, Amit K Prasad, Lev Chuntonov
Narrowband vibrational molecular transitions interacting with the broadband resonance of infrared plasmonic antennas lead to Fano lineshapes observed in linear (FTIR) and third-order (transient absorption and 2DIR) spectroscopic experiments. Both molecular and plasmonic components are inherently dissipative, and the effects associated with their coupling can be observed, in principle, when measuring the corresponding ultrafast quantum dynamics. We used 2DIR spectroscopy to study the waiting time evolution of quantum coherence excited in the carbonyl stretching modes of rhodium (acetylacetonato) dicarbonyl molecules, which were embedded in an 80 nm-thick polymer film spin-coated on an array of infrared half-wavelength gold antennas...
April 7, 2018: Journal of Chemical Physics
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