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https://www.readbyqxmd.com/read/28448801/the-placental-factor-in-spontaneous-preterm-birth-in-twin-vs-singleton-pregnancies
#1
Eran Weiner, Ann Dekalo, Ohad Feldstein, Elad Barber, Letizia Schreiber, Jacob Bar, Michal Kovo
OBJECTIVE: The association between infection and inflammatory response in singleton preterm birth (PTB) is well established, yet, less is known about PTB in twins. We aimed to compare the placental component and pregnancy outcome in pregnancies complicated with PTB of singletons vs. twin deliveries. We hypothesized that due to different underlying mechanisms, placental inflammatory lesions will be more prevalent in placentas derived from singleton pregnancies than twins. STUDY DESIGN: Labor characteristics, neonatal outcome and placental histopathology reports of spontaneous PTB at 24-33(6)/7 weeks, from 1/2008-12/2015, were reviewed...
April 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28448667/association-between-facial-rejuvenation-and-observer-ratings-of-youth-attractiveness-success-and-health
#2
Kristin L Bater, Lisa E Ishii, Ira D Papel, Theda C Kontis, Patrick J Byrne, Kofi D O Boahene, Jason C Nellis, Masaru Ishii
Importance: Surgical procedures for the aging face-including face-lift, blepharoplasty, and brow-lift-consistently rank among the most popular cosmetic services sought by patients. Although these surgical procedures are broadly classified as procedures that restore a youthful appearance, they may improve societal perceptions of attractiveness, success, and health, conferring an even larger social benefit than just restoring a youthful appearance to the face. Objectives: To determine if face-lift and upper facial rejuvenation surgery improve observer ratings of age, attractiveness, success, and health and to quantify the effect of facial rejuvenation surgery on each individual domain...
April 27, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28448046/a-novel-technique-for-raman-analysis-of-highly-radioactive-samples-using-any-standard-micro-raman-spectrometer
#3
Jean-Yves Colle, Mohamed Naji, Mark Sierig, Dario Manara
A novel approach for the Raman measurement of nuclear materials is reported in this paper. It consists of the enclosure of the radioactive sample in a tight capsule that isolates the material from the atmosphere. The capsule can optionally be filled with a chosen gas pressurized up to 20 bars. The micro-Raman measurement is performed through an optical-grade quartz window. This technique permits accurate Raman measurements with no need for the spectrometer to be enclosed in an alpha-tight containment. It therefore allows the use of all options of the Raman spectrometer, like multi-wavelength laser excitation, different polarizations, and single or triple spectrometer modes...
April 12, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28447865/a-versatile-stretch-sensor-for-measuring-physiological-movement-using-a-centre-loaded-end-supported-load-cell
#4
Syrpailyne Wankhar, Albert A Kota, Dheepak Selvaraj
Acquisition of movement of some body parts can provide important physiological information. In clinical practice as well as for research purposes different types of sensors such as piezoelectric crystals, conductive rubber and optical displacement sensors are used for such measurements. Each of these sensors is associated with its problems. This paper discusses the use of a stretch sensor constructed using a small metal bar, approximately the size of a zipper slider that can be sewn into a fabric in the form of a belt...
April 27, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/28447688/influence-of-cosolvents-self-crowding-temperature-and-pressure-on-the-sub-nanosecond-dynamics-and-folding-stability-of-lysozyme
#5
S R Al-Ayoubi, P H Schummel, M Golub, J Peters, R Winter
We studied the effects of temperature and hydrostatic pressure on the dynamical properties and folding stability of highly concentrated lysozyme solutions in the absence and presence of the osmolytes trimethylamine-N-oxide (TMAO) and urea. Elastic incoherent neutron scattering (EINS) was applied to determine the mean-squared displacement (MSD) of the protein's hydrogen atoms to yield insights into the effects of these cosolvents on the averaged sub-nanosecond dynamics in the pressure range from ambient up to 4000 bar...
April 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28445466/human-pluripotent-stem-cells-recurrently-acquire-and-expand-dominant-negative-p53-mutations
#6
Florian T Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier, Robert E Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A McCarroll, Kevin Eggan
Human pluripotent stem cells (hPS cells) can self-renew indefinitely, making them an attractive source for regenerative therapies. This expansion potential has been linked with the acquisition of large copy number variants that provide mutated cells with a growth advantage in culture. The nature, extent and functional effects of other acquired genome sequence mutations in cultured hPS cells are not known. Here we sequence the protein-coding genes (exomes) of 140 independent human embryonic stem cell (hES cell) lines, including 26 lines prepared for potential clinical use...
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28445085/regenerative-surgery-in-the-treatment-of-cosmetic-defect-following-nuss-procedure
#7
Flavio Facchini, Marco Ghionzoli, Alessandra Martin, Sara Tanini, Sara Ugolini, Roberto Lo Piccolo, Antonio Messineo
BACKGROUND: In the past decade, the minimally invasive repair of pectus excavatum (MIRPE) has become the treatment of choice for severe pectus excavatum (PE), proving acceptable to excellent cosmetic results. Recently, autologous fat grafting (FG) has been identified in aesthetic and reconstructive surgery to ideally handle volume and contour defects. We report our experience about FG in the treatment of residual minor defects after MIRPE and a proposal for a new indication of this largely adopted technique...
April 26, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28445012/drug-resistance-patterns-of-multidrug-and-extensively-drug-resistant-tuberculosis-in-korea-amplification-of-resistance-to-oral-second-line-drugs
#8
Chang Ki Kim, So Youn Shin, Hee Jin Kim, Kyungwon Lee
We aimed to analyze the drug resistance patterns of multidrug-resistant and extensively drug-resistant tuberculosis (TB) and the difference of drug resistance among various settings for health care in Korea. The data of drug susceptibility testing in 2009 was analyzed in order to secure sufficient number of patients from various settings in Korea. Patients were categorized by types of institutions into four groups, which comprised new and previously treated patients from public health care centers (PHC), the private sector, and Double-barred Cross clinics (DBC)...
July 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28444141/imaging-blood-brain-barrier-dysfunction-as-a-biomarker-for-epileptogenesis
#9
Guy Bar-Klein, Svetlana Lublinsky, Lyn Kamintsky, Iris Noyman, Ronel Veksler, Hotjensa Dalipaj, Vladimir V Senatorov, Evyatar Swissa, Dror Rosenbach, Netta Elazary, Dan Z Milikovsky, Nadav Milk, Michael Kassirer, Yossi Rosman, Yonatan Serlin, Arik Eisenkraft, Yoash Chassidim, Yisrael Parmet, Daniela Kaufer, Alon Friedman
A biomarker that will enable the identification of patients at high-risk for developing post-injury epilepsy is critically required. Microvascular pathology and related blood-brain barrier dysfunction and neuroinflammation were shown to be associated with epileptogenesis after injury. Here we used prospective, longitudinal magnetic resonance imaging to quantitatively follow blood-brain barrier pathology in rats following status epilepticus, late electrocorticography to identify epileptic animals and post-mortem immunohistochemistry to confirm blood-brain barrier dysfunction and neuroinflammation...
April 23, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28444014/photoelastic-analysis-of-stress-generated-by-connecticut-intrusion-arch-cia
#10
Alessandro Schwertner, Renato Rodrigues de Almeida, Alcides Gonini, Marcio Rodrigues de Almeida
OBJECTIVE: The present in vitro study evaluated, by means of the photoelastic technique, the effects generated by the Connecticut Intrusion Arch (CIA), with a 90o bend on the distal surface of molar tubes and using the 4 x 2 appliance on the anterior and posterior regions of the upper dental arch. METHODS: Five models were manufactured, in which two different clinical situations were correlated: 1) use of intrusion arch not cinched back and transpalatal bar for anchorage (Group 1); 2) use of intrusion arch cinched back and transpalatal bar for anchorage (Group 2)...
February 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28443865/simultaneous-use-of-mofs-mil-101-cr-and-zif-11-in-thin-film-nanocomposite-membranes-for-organic-solvent-nanofiltration
#11
Carlos Echaide-Górriz, Marta Navarro, Carlos Téllez, Joaquín Coronas
The MOFs Cr carboxylate MIL-101(Cr) and Zn imidazolate ZIF-11 have different chemical and textural properties. These properties have been combined to prepare thin film nanocomposite (TFN) membranes for organic solvent nanofiltration (OSN) with the two MOFs simultaneously embedded in the same membrane. The TFN membrane containing only ZIF-11 permeated faster than that with only MIL-101(Cr) when filtering sunset yellow (SY) (4.9 L m(-2) h(-1) bar(-1)) and acridine orange (AO) (3.2 L m(-2) h(-1) bar(-1)), although MIL-101(Cr) alone gave rise in both cases to better rejections (above 90%)...
April 26, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28443361/the-effect-of-alkali-on-the-product-distribution-from-black-liquor-conversion-under-supercritical-water
#12
Y Hawangchu, D Atong, V Sricharoenchaikul
Lignin in chemical pulping waste, or black liquor (BL), can be converted into various products via supercritical water gasification (SCWG). However, the inherited alkaline contents from the pulping chemicals may affect the product yields and properties. In this research, the influence of the residual alkali on the product distribution via SCWG of soda BL and kraft BL was evaluated. The SCWG was performed in a batch quartz reactor for 10 min at various temperatures (673, 773 and 873 K) and pressures (250, 300 and 400 bar)...
April 26, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28443021/functional-and-biochemical-endothelial-profiling-in-vivo-in-a-murine-model-of-endothelial-dysfunction-comparison-of-effects-of-1-methylnicotinamide-and-angiotensin-converting-enzyme-inhibitor
#13
Anna Bar, Mariola Olkowicz, Urszula Tyrankiewicz, Edyta Kus, Krzysztof Jasinski, Ryszard T Smolenski, Tomasz Skorka, Stefan Chlopicki
Although it is known that 1-methylnicotinamide (MNA) displays vasoprotective activity in mice, as yet the effect of MNA on endothelial function has not been demonstrated in vivo. Here, using magnetic resonance imaging (MRI) we profile the effects of MNA on endothelial phenotype in mice with atherosclerosis (ApoE/LDLR(-/-)) in vivo, in comparison to angiotensin (Ang) -converting enzyme (ACE) inhibitor (perindopril), with known vasoprotective activity. On a biochemical level, we analyzed whether MNA- or perindopril-induced improvement in endothelial function results in changes in ACE/Ang II-ACE2/Ang-(1-7) balance, and L-arginine/asymmetric dimethylarginine (ADMA) ratio...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28442004/multi-response-optimization-of-process-parameters-for-imidacloprid-removal-by-reverse-osmosis-using-taguchi-design
#14
Nevim Genç, Esra Can Doğan, Ali Oğuzhan Narcı, Emine Bican
  In this study, a multi-response optimization method using Taguchi's robust design approach is proposed for imidacloprid removal by reverse osmosis. Tests were conducted with different membrane type (BW30, LFC-3, CPA-3), transmembrane pressure (TMP = 20, 25, 30 bar), volume reduction factor (VRF = 2, 3, 4), and pH (3, 7, 11). Quality and quantity of permeate are optimized with the multi-response characteristics of the total dissolved solid (TDS), conductivity, imidacloprid, and total organic carbon (TOC) rejection ratios and flux of permeate...
May 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28440865/generation-of-wavy-structure-on-lipid-membrane-by-peripheral-proteins-a-linear-elastic-analysis
#15
Paritosh Mahata, Sovan Lal Das
We carry out a linear elastic analysis to study wavy structure generation on lipid membrane by peripheral membrane proteins. We model the lipid membrane as linearly elastic and anisotropic material. The hydrophobic insertion by proteins into the lipid membrane has been idealized as penetration of rigid rodlike inclusions into the membrane and the electrostatic interaction between protein and membrane has been modeled by a distributed surface traction acting on the membrane surface. With the proposed model we study curvature generation by several binding domains of peripheral membrane proteins containing BAR domains and amphipathic alpha-helices...
April 25, 2017: FEBS Letters
https://www.readbyqxmd.com/read/28440593/single-domain-ferromagnet-of-noncentrosymmetric-uniaxial-magnetic-ions-and-magnetoelectric-interaction
#16
Hyun-Joo Koo, Elijah E Gordon, Myung-Hwan Whangbo
The feasibility of a single-domain ferromagnet based on uniaxial magnetic ions was examined. For a noncentrosymmetric uniaxial magnetic ion of magnetic moment μ at a site of local electric dipole moment p, it is unknown to date whether μ prefers to be parallel or antiparallel to μ. The nature of this magnetoelectric interaction was probed in terms of analogical reasoning based on the Rashba effect and density functional theory (DFT) calculations. We show that μ and p prefer an antiparallel arrangement, predict that Fe-doped CaZnOS is a single-domain ferromagnet like a bar magnet, and find the probable cause for the ferromagnetism and weak magnetization hysteresis in Fe-doped hexagonal ZnO and ZnS at very low dopant concentrations...
April 25, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28439277/expression-of-pennisetum-glaucum-eukaryotic-translational-initiation-factor-4a-pgeif4a-confers-improved-drought-salinity-and-oxidative-stress-tolerance-in-groundnut
#17
Tata Santosh Rama Bhadra Rao, Juturu Vijaya Naresh, Palakolanu Sudhakar Reddy, Malireddy K Reddy, Garladinne Mallikarjuna
Eukaryotic translational initiation factor 4A belong to family of helicases, involved in multifunctional activities during stress and non-stress conditions. The eIF4A gene was isolated and cloned from semi-arid cereal crop of Pennisetum glaucum. In present study, the PgeIF4A gene was expressed under the regulation of stress inducible Arabidopsis rd29A promoter in groundnut (cv JL-24) with bar as a selectable marker. The de-embryonated cotyledons were infected with Agrobacterium tumefaciens (LBA4404) carrying rd29A:PgeIF4A construct and generated high frequency of multiple shoots in phosphinothricin medium...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28438696/altered-temporal-lobe-white-matter-lipid-ion-profiles-in-an-experimental-model-of-sporadic-alzheimer-s-disease
#18
Ming Tong, Raiane Leão, Gina V Vimbela, Emine B Yalcin, Jared Kay, Alexander Krotow, Suzanne M de la Monte
BACKGROUND: White matter is an early and important yet under-evaluated target of Alzheimer's disease (AD). Metabolic impairments due to insulin and insulin-like growth factor resistance contribute to white matter degeneration because corresponding signal transduction pathways maintain oligodendrocyte function and survival. METHODS: This study utilized a model of sporadic AD in which adult Long Evans rats administered intracerebral streptozotocin (i.c. STZ) developed AD-type neurodegeneration...
April 21, 2017: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/28438525/sociodemographic-factors-associated-with-trans-female-youth-s-access-to-health-care-in-the-san-francisco-bay-area
#19
Elizabeth A Johns, Harry Jin, Colette L Auerswald, Erin C Wilson
PURPOSE: Trans*female youth (TFY) are an underserved population at risk for a variety of poor health outcomes, in part related to barriers to accessing health and mental health care. METHODS: We conducted a secondary analysis of data collected with 250 TFY aged 16-24 years in the San Francisco Bay Area from 2012 to 2014. Logistic regression was used to test associations between sociodemographic variables and barriers to gender identity-based medical and mental health care...
April 21, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28438153/damage-to-the-macula-associated-with-led-derived-blue-laser-exposure-a-case-report
#20
Lingling Liang, Zhihua Cui, Chengwei Lu, Qian Hao, Yajuan Zheng
BACKGROUND: Light emitting diodes laser is emerging as an important source of light replacing conventional lights. It is widely used for illumination in the bar where young people love to go. But not everyone knows about the light damage to the eye especially to the macula. In this article, we report the case of a macular damage induced by LED-derived blue laser in a bar, studied with optical coherence tomography (OCT) to evaluate the retinal lesion and multifocal electroretinography (mfERG) to evaluate functional damage...
April 24, 2017: BMC Ophthalmology
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