keyword
MENU ▼
Read by QxMD icon Read
search

BAR

keyword
https://www.readbyqxmd.com/read/28734255/use-of-electronic-cigarettes-in-public-and-private-settings-in-barcelona-spain
#1
Nuria Matilla-Santander, Marcela Fu, Montse Ballbè, Kailey Bunch, Cristina Lidón-Moyano, Juan Carlos Martín-Sánchez, Esteve Fernández, Jose M Martínez-Sánchez
OBJECTIVES: To describe the prevalence of e-cigarette users who use them in selected indoor public and workplaces, and private venues in Barcelona (Spain) in 2015. METHODS: This is a cross-sectional study of a sample of e-cigarette users (≥ 18 years) from Barcelona (n = 600). We calculated the proportion of e-cigarette users who used the device in public and private settings (in the last 30 days). We fit multivariate logistic regression models adjusted for sex and age to calculate the odds ratios (OR) with their 95% confidence intervals (CI) of e-cigarette use by socio-demographic factors, dual use and nicotine-containing e-cigarettes...
July 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28732022/global-economic-trade-offs-between-wild-nature-and-tropical-agriculture
#2
Luis R Carrasco, Edward L Webb, William S Symes, Lian P Koh, Navjot S Sodhi
Global demands for agricultural and forestry products provide economic incentives for deforestation across the tropics. Much of this deforestation occurs with a lack of information on the spatial distribution of benefits and costs of deforestation. To inform global sustainable land-use policies, we combine geographic information systems (GIS) with a meta-analysis of ecosystem services (ES) studies to perform a spatially explicit analysis of the trade-offs between agricultural benefits, carbon emissions, and losses of multiple ecosystem services because of tropical deforestation from 2000 to 2012...
July 2017: PLoS Biology
https://www.readbyqxmd.com/read/28731731/current-driven-instability-of-the-quantum-anomalous-hall-effect-in-ferromagnetic-topological-insulators
#3
Minoru Kawamura, Ryutaro Yoshimi, Atsushi Tsukazaki, Kei S Takahashi, Masashi Kawasaki, Yoshinori Tokura
The instability of the quantum anomalous Hall (QAH) effect has been studied as a function of the electric current and temperature in ferromagnetic topological insulator thin films. We find that a characteristic current for the breakdown of the QAH effect is roughly proportional to the Hall-bar width, indicating that the Hall electric field is relevant to the breakdown. We also find that electron transport is dominated by variable range hopping (VRH) at low temperatures. Combining the current and temperature dependences of the conductivity in the VRH regime, the localization length of the QAH state is evaluated to be about 5  μm...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731688/the-%C3%AF-configuration-of-the-www-motif-of-a-short-trp-rich-peptide-is-critical-for-targeting-bacterial-membranes-disrupting-preformed-biofilms-and-killing-methicillin-resistant-staphylococcus-aureus
#4
D Zarena, Biswajit Mishra, Tamara Lushnikova, Fangyu Wang, Guangshun Wang
Tryptophan-rich peptides, being short and suitable for large-scale chemical synthesis, are attractive candidates for developing a new generation of antimicrobials to combat antibiotic-resistant bacteria (superbugs). Although there are numerous pictures for membrane-bound structure of a single tryptophan (W), how multiple Trp amino acids assemble themselves and interact with bacterial membranes are poorly understood. This communication presents the three-dimensional structure for an eight-residue Trp-rich peptide (WWWLRKIW-NH2 with 50% W) determined by the improved 2D NMR method, which includes the measurements of 13C and 15N chemical shifts at natural abundance...
July 21, 2017: Biochemistry
https://www.readbyqxmd.com/read/28731163/-corrigendum-fuca1-is-induced-by-wild-type-p53-and-expressed-at-different-levels-in-thyroid-cancers-depending-on-p53-status
#5
Nobuo Tsuchida, Masa-Aki Ikeda, Yoshizumu Ishino, Michele Grieco, Giancarlo Vecchio
Subsequent to the publication of the above paper, the authors noted that there was an error on Fig. 4 of page 2046, in which the symbols of α-L-fucosidase 1 (FUCA1) and fucosyltransferase 8 (FUT8) had been mistakenly labelled the wrong way around (FUCA1 should have been represented by the blue bars, and FUT8 by the red). The corrected version of Fig. 4 is shown below, which now accurately shows how average levels of FUCA1 mRNA were low in the anaplastic thyroid cancer samples (ATCs), whereas expression levels in the papillary thyroid cancer samples (PTCs) were comparable, or slightly higher, than those present in normal thyroid tissues...
July 21, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28730743/inulin-type-fructans-and-whey-protein-both-modulate-appetite-but-only-fructans-alter-gut-microbiota-in-adults-with-overweight-obesity-a-randomized-controlled-trial
#6
Raylene A Reimer, Holly J Willis, Jasmine M Tunnicliffe, Heekuk Park, Karen L Madsen, Adriana Soto-Vaca
SCOPE: Independently, prebiotics and dietary protein have been shown to improve weight loss and/or alter appetite. Our objective was to determine the effect of combined prebiotic and whey protein on appetite, body composition and gut microbiota in adults with overweight/obesity. METHODS AND RESULTS: In a 12 week, placebo-controlled, double-blind study, 125 adults with overweight/obesity were randomly assigned to receive isocaloric snack bars of: 1) Control; 2) Inulin-type fructans (ITF); 3) Whey protein; 4) ITF + Whey protein...
July 21, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28730716/manganese-i-catalyzed-enantioselective-hydrogenation-of-ketones-using-a-defined-chiral-pnp-pincer-ligand
#7
Marcel Garbe, Kathrin Junge, Svenja Walker, Zhihong Wei, Haijun Jiao, Anke Spannenberg, Stephan Bachmann, Michelangelo Scalone, Matthias Beller
A new chiral manganese PNP pincer complex is described. Asymmetric hydrogenation of several prochiral ketones with molecular hydrogen in the presence of this complex proceeds under mild conditions (40 °C, 4 h, 30 bar H₂). Besides high catalytic activity for aromatic substrates, aliphatic ketones are hydrogenated with remarkable selectivities (er up to 92:8). DFT calculations support an outer sphere hydrogenation mechanism as well as the experimentally determined stereochemistry.
July 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28729890/varieties-of-confidence-intervals
#8
Denis Cousineau
Error bars are useful to understand data and their interrelations. Here, it is shown that confidence intervals of the mean (CI M s) can be adjusted based on whether the objective is to highlight differences between measures or not and based on the experimental design (within- or between-group designs). Confidence intervals (CIs) can also be adjusted to take into account the sampling mechanisms and the population size (if not infinite). Names are proposed to distinguish the various types of CIs and the assumptions underlying them, and how to assess their validity is explained...
2017: Advances in Cognitive Psychology
https://www.readbyqxmd.com/read/28729671/linking-rheology-and-printability-for-dense-and-strong-ceramics-by-direct-ink-writing
#9
Amin M'Barki, Lydéric Bocquet, Adam Stevenson
Direct ink writing of dense and strong ceramic objects remains an important open challenge. We develop a universal dimensionless criterion for printing such objects. Boehmite, an Al2O3 precursor, was used to assess the rheological properties leading to dense structures in ceramics manufactured by direct ink writing. Boehmite suspensions undergo time dependent gelation, thus providing a rheological laboratory of flow behaviours that can be correlated with printability requirements. We measured the evolution of rheological properties over several days and quantified the deformation of simple printed shapes at different aging times...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729337/raising-the-bar-for-chronic-gvhd-trials
#10
Nicolaus Kröger
No abstract text is available yet for this article.
July 20, 2017: Blood
https://www.readbyqxmd.com/read/28729161/the-neural-basis-of-precise-visual-short-term-memory-for-complex-recognisable-objects
#11
Michele Veldsman, Daniel J Mitchell, Rhodri Cusack
Recent evidence suggests that visual short-term memory (VSTM) capacity estimated using simple objects, such as colours and oriented bars, may not generalise well to more naturalistic stimuli. More visual detail can be stored in VSTM when complex, recognisable objects are maintained compared to simple objects. It is not yet known if it is recognisability that enhances memory precision, nor whether maintenance of recognisable objects is achieved with the same network of brain regions supporting maintenance of simple objects...
July 17, 2017: NeuroImage
https://www.readbyqxmd.com/read/28728580/lumbar-microdiscectomy-and-post-operative-activity-restrictions-a-protocol-for-a-single-blinded-randomised-controlled-trial
#12
Chris D Daly, Kai Zheong Lim, Jennifer Lewis, Kelly Saber, Mohammed Molla, Naor Bar-Zeev, Tony Goldschlager
BACKGROUND: Lumbar microdiscectomy is the most commonly performed spinal surgery procedure, with over 300,000 cases performed annually in the United States alone. Traditionally, patients were advised to restrict post-operative activity as this was believed to reduce the risk of disc reherniation and progressive instability. However, this practice would often delay patients return to work. In contemporary practice many surgeons do not restrict patient post-operative activity due to the perception this practice is unnecessary...
July 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28726968/evaluation-of-spectral-photon-counting-computed-tomography-k-edge-imaging-for-determination-of-gold-nanoparticle-biodistribution-in-vivo
#13
Salim Si-Mohamed, David P Cormode, Daniel Bar-Ness, Monica Sigovan, Pratap C Naha, Jean-Baptiste Langlois, Lara Chalabreysse, Philippe Coulon, Ira Blevis, Ewald Roessl, Klaus Erhard, Loic Boussel, Philippe Douek
Spectral photon counting computed tomography (SPCCT) is an emerging medical imaging technology. SPCCT scanners record the energy of incident photons, which allows specific detection of contrast agents due to measurement of their characteristic X-ray attenuation profiles. This approach is known as K-edge imaging. Nanoparticles formed from elements such as gold, bismuth or ytterbium have been reported as potential contrast agents for SPCCT imaging. Furthermore, gold nanoparticles have many applications in medicine, such as adjuvants for radiotherapy and photothermal ablation...
July 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28726827/nitrogen-reduction-and-functionalization-by-a-multimetallic-uranium-nitride-complex
#14
Marta Falcone, Lucile Chatelain, Rosario Scopelliti, Ivica Živković, Marinella Mazzanti
Molecular nitrogen (N2) is cheap and widely available, but its unreactive nature is a challenge when attempting to functionalize it under mild conditions with other widely available substrates (such as carbon monoxide, CO) to produce value-added compounds. Biological N2 fixation can do this, but the industrial Haber-Bosch process for ammonia production operates under harsh conditions (450 degrees Celsius and 300 bar), even though both processes are thought to involve multimetallic catalytic sites. And although molecular complexes capable of binding and even reducing N2 under mild conditions are known, with co-operativity between metal centres considered crucial for the N2 reduction step, the multimetallic species involved are usually not well defined, and further transformation of N2-binding complexes to achieve N-H or N-C bond formation is rare...
July 19, 2017: Nature
https://www.readbyqxmd.com/read/28725208/aldo-van-eyck-s-playgrounds-aesthetics-affordances-and-creativity
#15
Rob Withagen, Simone R Caljouw
After World War II, the Dutch architect Aldo van Eyck developed hundreds of playgrounds in the city of Amsterdam. These public playgrounds were located in parks, squares, and derelict sites, and consisted of minimalistic aesthetic play equipment that was supposed to stimulate the creativity of children. Over the last decades, these playgrounds have been studied by sociologists, theorists of art and architecture, and psychologists. Adopting an ecological approach to the human environment, it is argued that the abstract forms of van Eyck's play sculptures indeed stimulate the creativity of the child...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28725048/cd300f-il-5-cross-talk-inhibits-adipose-tissue-eosinophil-homing-and-subsequent-il-4-production
#16
Perri Rozenberg, Hadar Reichman, Israel Zab-Bar, Michal Itan, Metsada Pasmanik-Chor, Carine Bouffi, Udi Qimron, Ido Bachelet, Patricia C Fulkerson, Marc E Rothenberg, Ariel Munitz
Eosinophils and their associated cytokines IL-4 and IL-5 are emerging as central orchestrators of the immune-metabolic axis. Herein, we demonstrate that cross-talk between the Ig-superfamily receptor CD300f and IL-5 is a key checkpoint that modifies the ability of eosinophils to regulate metabolic outcomes. Generation of Il5 (Tg) /Cd300f (-/-) mice revealed marked and distinct increases in eosinophil levels and their production of IL-4 in the white and brown adipose tissues. Consequently, Il5 (Tg) /Cd300f (-/-) mice had increased alternatively activated macrophage accumulation in the adipose tissue...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724773/nkp46-recognizes-the-sigma1-protein-of-reovirus-implications-for-reovirus-based-cancer-therapy
#17
Yotam Bar-On, Yoav Charpak-Amikam, Ariella Glasner, Batya Isaacson, Alexandra Duev-Cohen, Pinchas Tsukerman, Alexander Varvak, Michal Mandelboim, Ofer Mandelboim
The recent approval of onclolytic virus for therapy of melanoma patients has increased the need for precise evaluation of the mechanisms by which oncolytic viruses affect tumor growth. Here we show that the human NK activating receptor, NKp46, and its mouse orthologous protein, NCR1, recognize the reovirus sigma1 protein in a sialic-acid-dependent manner. We identify NKp46/NCR1 binding sites to sigma1 and show that sigma1 binding by NKp46/NCR1 leads to NK cell activation in vitro Finally, we demonstrate that NCR1 activation is essential for reovirus-based therapy in vivo Collectively, we identified sigma1 as a novel ligand for NKp46/NCR1 and demonstrated that NKp46/NCR1 is needed for both clearance of reovirus infections and reovirus-based tumor therapy...
July 19, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28723562/integrative-genomics-identifies-the-molecular-basis-of-resistance-to-azacitidine-therapy-in-myelodysplastic-syndromes
#18
Ashwin Unnikrishnan, Elli Papaemmanuil, Dominik Beck, Nandan P Deshpande, Arjun Verma, Ashu Kumari, Petter S Woll, Laura A Richards, Kathy Knezevic, Vashe Chandrakanthan, Julie A I Thoms, Melinda L Tursky, Yizhou Huang, Zara Ali, Jake Olivier, Sally Galbraith, Austin G Kulasekararaj, Magnus Tobiasson, Mohsen Karimi, Andrea Pellagatti, Susan R Wilson, Robert Lindeman, Boris Young, Raj Ramakrishna, Christopher Arthur, Richard Stark, Philip Crispin, Jennifer Curnow, Pauline Warburton, Fernando Roncolato, Jacqueline Boultwood, Kevin Lynch, Sten Eirik W Jacobsen, Ghulam J Mufti, Eva Hellstrom-Lindberg, Marc R Wilkins, Karen L MacKenzie, Jason W H Wong, Peter J Campbell, John E Pimanda
Myelodysplastic syndromes and chronic myelomonocytic leukemia are blood disorders characterized by ineffective hematopoiesis and progressive marrow failure that can transform into acute leukemia. The DNA methyltransferase inhibitor 5-azacytidine (AZA) is the most effective pharmacological option, but only ∼50% of patients respond. A response only manifests after many months of treatment and is transient. The reasons underlying AZA resistance are unknown, and few alternatives exist for non-responders. Here, we show that AZA responders have more hematopoietic progenitor cells (HPCs) in the cell cycle...
July 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28723561/crosstalk-between-regulatory-t-cells-and-tumor-associated-dendritic-cells-negates-anti-tumor-immunity-in-pancreatic-cancer
#19
Jung-Eun Jang, Cristina H Hajdu, Caroline Liot, George Miller, Michael L Dustin, Dafna Bar-Sagi
Regulatory T (Treg) cell infiltration constitutes a prominent feature of pancreatic ductal adenocarcinoma (PDA). However, the immunomodulatory function of Treg cells in PDA is poorly understood. Here, we demonstrate that Treg cell ablation is sufficient to evoke effective anti-tumor immune response in early and advanced pancreatic tumorigenesis in mice. This response is dependent on interferon-γ (IFN-γ)-producing cytotoxic CD8(+) T cells. We show that Treg cells engage in extended interactions with tumor-associated CD11c(+) dendritic cells (DCs) and restrain their immunogenic function by suppressing the expression of costimulatory ligands necessary for CD8(+) T cell activation...
July 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28723218/aluminum-chloride-mediated-dieckmann-cyclization-for-the-synthesis-of-cyclic-2-alkyl-1-3-alkanediones-one-step-synthesis-of-the-chiloglottones
#20
Ahlam M Armaly, Sukanta Bar, Corinna S Schindler
Cyclic 2-alkyl-1,3-alkanediones are ubiquitous structural motifs in many natural products of biological importance. Reported herein is an AlCl3·MeNO2-mediated Dieckmann cyclization reaction of general synthetic utility that enables direct access to complex 2-alkyl-1,3-dione building blocks from readily available dicarboxylic acid and acid chloride substrates. This new strategy enables direct synthetic access to the chiloglottone plant pheromones from commercial material in a single synthetic transformation...
July 19, 2017: Organic Letters
keyword
keyword
81552
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"