keyword
MENU ▼
Read by QxMD icon Read
search

Psychiatric drug

keyword
https://www.readbyqxmd.com/read/29224006/epigenetic-regulation-of-the-promotor-region-of-vascular-endothelial-growth-factor-a-and-nerve-growth-factor-in-opioid-maintained-patients
#1
Adrian Groh, Kirsten Jahn, Alexandra Burkert, Alexandra Neyazi, Laura Schares, Eva Janke, Marie Rehme, Rilana Schuster, Thomas Hillemacher, Stefan Bleich, Helge Frieling, Annemarie Heberlein
AIMS: The nerve growth factor (NGF) and the vascular endothelial growth factor-A (VEGF-A) may be of importance for psychiatric diseases including substance use disorders. The aim of the study was to identify differences in the regulation of both neuropeptides via the DNA-methylation status of the promotor regions of NGF and VEGF-A in different forms of maintenance therapy for opioid dependence and the related stress regulation via the hypothalamic-pituitary-adrenal axis. METHODS: We compared methylation levels of opioid-dependent patients receiving treatment with diamorphine (n = 28) or levomethadone (n = 54) and similar levels in a healthy control group (n = 72)...
December 8, 2017: European Addiction Research
https://www.readbyqxmd.com/read/29223397/-borneol-suppresses-conditioned-fear-recall-and-anxiety-like-behaviors-in-mice
#2
Bo Cao, Huan-Yu Ni, Jun Li, Ying Zhou, Xin-Lan Bian, Yan Tao, Cheng-Yun Cai, Cheng Qin, Hai-Yin Wu, Lei Chang, Chun-Xia Luo, Dong-Ya Zhu
Fear- and anxiety-related psychiatric disorders have been one of the major chronic diseases afflicting patients for decades, and new compounds for treating such disorders remain to be developed. (+)-Borneol, a bicyclic monoterpene found in several species of Artemisia and Dipterocarpaceae, is widely used for anxiety, pain and anesthesia in Chinese medicine. Meanwhile, it can potentiate GABA (γ-aminobutyric acid) activity directly in recombinant GABAA receptors. The present study was to investigate the effects of (+)-Borneol on both contextual and cued fear recall...
December 6, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29221470/potential-diagnostic-markers-of-olanzapine-efficiency-for-acute-psychosis-a-focus-on-peripheral-biogenic-amines
#3
A E Taraskina, R F Nasyrova, A M Zabotina, D N Sosin, К А Sosina, E E Ershov, M N Grunina, E M Krupitsky
BACKGROUND: Biomarkers are now widely used in many fields of medicine, and the identification of biomarkers that predict antipsychotic efficacy and adverse reactions is a growing area of psychiatric research. Monoamine molecules of the peripheral bloodstream are possible prospective biomarkers based on a growing body of evidence indicating that they may reflect specific changes in neurotransmitters in the brain. The aim of this study was to detect peripheral biogenic amine indicators of patients with acute psychosis and to test the correlations between the biological measures studied and the psychopathological status of the patients...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29220682/searching-online-to-buy-commonly-prescribed-psychiatric-drugs
#4
Scott Monteith, Tasha Glenn
The use of online pharmacies to purchase prescription drugs is increasing. The patient experience when searching to buy commonly prescribed psychiatric drugs was investigated. Using the search term "buy [drug name] online" in Google, 38 frequently prescribed drugs, including 13 with a high potential for abuse, were searched by brand and generic names. The first page of results were analyzed, including with pharmacy certification checkers and ICANN WHOIS. Search results for all drugs yielded 167 pharmacies, of which 147 (88%) did not require a prescription...
November 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29220679/interaction-between-pre-treatment-drug-use-and-heterogeneity-of-psychiatric-diagnosis-predicts-outcomes-in-outpatients-with-co-occurring-disorders
#5
Oladunni Oluwoye, Katherine Hirchak, Emily Leickly, Jordan Skalisky, Sterling McPherson, Debra Srebnik, John M Roll, Richard K Ries, Michael G McDonell
We examined whether the interaction of baseline stimulant use, assessed by urine drug tests, and type of serious mental illness (SMI) diagnosis predicted stimulant use in a trial of contingency management (CM). The interaction between baseline stimulant use and SMI diagnoses was significant in the overall sample (p=0.002) when controlling for the main effects of treatment condition, baseline stimulant use, and SMI diagnosis. Similar results were also found within the CM sample. Individuals with bipolar disorder were more or less likely, depending on their baseline stimulant-drug test results, to use stimulants during treatment compared to those with other SMI diagnoses...
November 29, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29219015/correction-to-zaleski-et%C3%A2-al-guidelines-of-the-brazilian-association-of-studies-on-alcohol-and-other-drugs-abead-for-diagnosis-and-treatment-of-psychiatric-comorbidity-with-alcohol-and-other-substance-and-dependence
#6
https://www.readbyqxmd.com/read/29218228/similar-adverse-events-from-two-disparate-agents-implicate-lipid-inflammatory-mediators-for-a-role-in-anxiety-states
#7
Gordon C McCarter, Lauren B Blanchard
We recently reported a case in which a 54-year-old male experienced maintenance insomnia, generalized anxiety and panic symptoms associated with consumption of a fish oil supplement enriched in eicosapentaenoic acid (EPA). We report here that the same patient has experienced identical but more severe symptoms in response to the use of the leukotriene receptor antagonist montelukast, in accordance with other cases reported to the Food and Drug Administration. Since omega-3 fatty acids like EPA are precursors for the biosynthesis of eicosanoids including leukotrienes, a common factor to these psychiatric adverse events may be perturbations in this highly complex system of lipid inflammatory mediators...
November 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29217682/overexpression-of-the-histone-dimethyltransferase-g9a-in-nucleus-accumbens-shell-increases-cocaine-self-administration-stress-induced-reinstatement-and-anxiety
#8
Ethan M Anderson, Erin B Larson, Daniel Guzman, Anne Marie Wissman, Rachael L Neve, Eric J Nestler, David W Self
Repeated exposure to cocaine induces lasting epigenetic changes in neurons that promote the development and persistence of addiction. One epigenetic alteration involves reductions in levels of the histone dimethyltransferase, G9a, in nucleus accumbens (NAc) after chronic cocaine administration. This reduction in G9a may enhance cocaine reward since overexpressing G9a in the NAc decreases cocaine-conditioned place preference. Thus, we hypothesized that HSV-mediated G9a overexpression in the NAc shell (NAcSh) would attenuate cocaine self-administration and cocaine-seeking behavior...
December 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29212415/effects-of-cognitive-remediation-on-cognitive-and-social-functions-in-individuals-with-schizophrenia
#9
Akihiko Katsumi, Hiroshi Hoshino, Satoshi Fujimoto, Hirooki Yabe, Emi Ikebuchi, Kazuyuki Nakagome, Shin-Ichi Niwa
Individuals with schizophrenia exhibit cognitive impairments, which are related to impairments in social functions. This study investigated the effects of cognitive remediation on cognitive, social, and daily living impairment. Participants were individuals with schizophrenia between 20 and 60 years old (N = 44). Participants were randomly assigned to two groups: a cognitive remediation intervention group and a non-intervention control group. The control group was provided with conventional drug therapy and either day care or occupational therapy...
December 7, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29210144/adolescent-impulsivity-as-a-sex-dependent-and-subtype-dependent-predictor-of-impulsivity-alcohol-drinking-and-dopamine-d2-receptor-expression-in-adult-rats
#10
Lindsey R Hammerslag, Amogh P Belagodu, Olubankole A Aladesuyi Arogundade, Angela G Karountzos, Qingrou Guo, Roberto Galvez, Brent W Roberts, Joshua M Gulley
Impulsivity is a personality trait associated with a heightened risk for drug use and other psychiatric conditions. Because impulsivity-related disorders typically emerge during adolescence, there has been interest in exploring methods for identifying adolescents that will be at risk to develop substance use disorders in adulthood. Here, we used a rodent model to assess inhibitory control (impulsive action) and impulsive decision making (impulsive choice) during adolescence (43-50 days old) or adulthood (93-100 days old) and then examined the impact of development on these impulsivity traits by re-testing rats 50 days later...
December 5, 2017: Addiction Biology
https://www.readbyqxmd.com/read/29209753/-neuroleptic-malignant-syndrome
#11
REVIEW
R Knorr, J Schöllkopf, E Haen
BACKGROUND: Neuroleptic malignant syndrome (NMS) is a rare but severe undesired complication of psychopharmacological treatment. The mortality has shown a significant decrease since its first description. Knowledge of NMS is important for every clinician because of the need for rapid diagnosis and treatment. OBJECTIVE: This article presents a review and critical appraisal of the current study situation for NMS. Recommendations for diagnostics, differential diagnostics and treatment are presented particularly from a clinical perspective...
December 5, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29207008/cannabis-use-and-hypomania-in-young-people-a-prospective-analysis
#12
Steven Marwaha, Catherine Winsper, Paul Bebbington, Daniel Smith
Background: Cannabis use in young people is common and associated with psychiatric disorders. However, the prospective link between cannabis use and bipolar disorder symptoms has rarely been investigated. The study hypothesis was that adolescent cannabis use is associated with hypomania in early adulthood via several potential etiological pathways. Methods: Data were used from the Avon Longitudinal Study of Parents and Children, a UK birth cohort study. The prospective link between cannabis use at age 17 and hypomania at age 22-23 years was tested using regression analysis, adjusted for gender, early environmental risk factors, alcohol and drug use, and depression and psychotic symptoms at age 18 years...
November 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29206984/rational-urine-drug-monitoring-in-patients-receiving-opioids-for-chronic-pain-consensus-recommendations
#13
Charles E Argoff, Daniel P Alford, Jeffrey Fudin, Jeremy A Adler, Matthew J Bair, Richard C Dart, Roy Gandolfi, Bill H McCarberg, Steven P Stanos, Jeffrey A Gudin, Rosemary C Polomano, Lynn R Webster
Objective: To develop consensus recommendations on urine drug monitoring (UDM) in patients with chronic pain who are prescribed opioids. Methods: An interdisciplinary group of clinicians with expertise in pain, substance use disorders, and primary care conducted virtual meetings to review relevant literature and existing guidelines and share their clinical experience in UDM before reaching consensus recommendations. Results: Definitive (e...
December 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29205691/intravenous-immunoglobulin-in-drug-and-device-refractory-patients-with-the-symptoms-of-gastroparesis-an-open-label-study
#14
M Ashat, A Lewis, H Liaquat, A Stocker, L McElmurray, V Vedanarayanan, K Soota, T Howell, A Kedar, J Obert, T L Abell
BACKGROUND: Gastroparesis is a complex clinical entity; many aspects of which remain unknown. Although most patients have idiopathic, diabetic, or postsurgical gastroparesis, many are thought to have measurable neuromuscular abnormalities. Immunotherapy has recently been utilized to treat suspected autoimmune gastrointestinal dysmotility. METHODS: Fourteen patients with symptoms of gastroparesis (Gp) who were refractory to drug/device were selected from 443 Gp patients from 2013 to 2015 who were treated at the University of Louisville motility center...
December 4, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29203842/tolerability-and-adequate-therapeutic-dosage-of-oral-clomipramine-for-the-treatment-of-premature-ejaculation-a-randomized-double-blind-placebo-controlled-fixed-dose-parallel-grouped-clinical-study
#15
Sae Woong Kim, Jin Bong Choi, Su Jin Kim, Kyung Soo Kim, Churl Min Kim, Dong Hyeon Lee, Whan Seok Choi
To evaluate the adequate therapeutic dosage of clomipramine 15 mg/day and clomipramine 30 mg/day in male patients with premature ejaculation (PE), this study enrolled men aged 20-65 years who met diagnostic criteria for PE including Intravaginal Ejaculation Latency Time (IELT) less than 2 min for at least 75% of their sexual intercourses. Subjects received placebo, clomipramine 15 mg, or clomipramine 30 mg prn (2~6 h before intercourse) for 4 weeks. Efficacy was assessed using fold change, percentile change, and mean change of IELT, as well as Drug Coitus Interval Time (DCIT)...
December 4, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29203502/characteristics-of-nps-use-in-patients-admitted-to-acute-psychiatric-services-in-southeast-scotland-a-retrospective-cross-sectional-analysis-following-public-health-interventions
#16
Kyle H Bennett, Helen M Hare, Robert M Waller, Helen L Alderson, Stephen Lawrie
OBJECTIVES: Assess the impact of selective prohibition and seizure of novel psychoactive substances (NPS) supply on NPS use prevalence within psychiatric admissions and evaluate demographic characteristics of current NPS users. DESIGN: A 6-month retrospective cross-sectional analysis of discharge letters between 1 October 2015 and 31 March 2016. SETTING: General psychiatry inpatients and intensive home treatment team (IHTT) community patients at a psychiatric hospital in a Scottish city...
December 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29201800/effect-of-different-sedation-regimes-on-cognitive-functions-in-colonoscopy
#17
Perihan Ekmekçi, Gulbanu Erkan, Hakan Yilmaz, Baturay K Kazbek, Ulku C Köksoy, Güler Doganay, Doganay Filiz Tüzüner
Aim: To compare the effects of propofol/remifentanil and meperidine/midazolam on postprocedure cognitive function. Materials and methods: A total of 100 American Society of Anesthesiologists (ASA) score I to III patients undergoing elective colonoscopy were taken into the study and divided into two groups. Exclusion criteria were patient refusal, mini mental test (MMT) <26, The Amsterdam Preoperative Anxiety and Information Scale (APAIS) >10, advanced cardiopulmonary or psychiatric disease, chronic alcohol abuse, morbid obesity, and known allergy to study drugs...
July 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29201344/combinations-of-qtc-prolonging-drugs-towards-disentangling-pharmacokinetic-and-pharmacodynamic-effects-in-their-potentially-additive-nature
#18
Andreas D Meid, Irene Bighelli, Sarah Mächler, Gerd Mikus, Giuseppe Carrà, Mariasole Castellazzi, Claudio Lucii, Giovanni Martinotti, Michela Nosè, Giovanni Ostuzzi, Corrado Barbui, Walter E Haefeli
Background: Whether arrhythmia risks will increase if drugs with electrocardiographic (ECG) QT-prolonging properties are combined is generally supposed but not well studied. Based on available evidence, the Arizona Center for Education and Research on Therapeutics (AZCERT) classification defines the risk of QT prolongation for exposure to single drugs. We aimed to investigate how combining AZCERT drug categories impacts QT duration and how relative drug exposure affects the extent of pharmacodynamic drug-drug interactions...
December 2017: Therapeutic Advances in Psychopharmacology
https://www.readbyqxmd.com/read/29200972/problems-and-service-needs-among-ex-offenders-with-hiv-risk-behaviors-entering-sober-living-recovery-homes
#19
Douglas L Polcin, Rachael Korcha, Amy A Mericle, Elizabeth Mahoney, Jordana Hemberg
There is currently a nationwide effort to decrease the number of persons who are incarcerated in jails and prisons. However, many ex-offenders on probation or parole do not have access to affordable housing and larger proportions have histories of HIV risk as well as substance abuse problems. In California, sober living houses (SLHs) are becoming an increasingly popular housing option for these individuals. Based largely on the principles of Alcoholics Anonymous (AA), SLHs require abstinence from alcohol and drugs and provide peer support for recovery...
2017: Criminal Justice Studies (Abingdon, England)
https://www.readbyqxmd.com/read/29200567/the-menacing-side-of-valproate-a-case-series-of-valproate-induced-hyperammonemia
#20
Deeksha Elwadhi, Rashmi Prakash, Manushree Gupta
Valproate (VPA) is a well-tolerated and commonly used drug to treat variety of psychiatric and neurological disorders. VPA-induced hyperammonemic encephalopathy is a rare adverse effect which can commonly occur in the background of normal liver function and therapeutic serum levels. Any delay in treatment of VPA-induced hyperammonemic encephalopathy can lead to life-threatening coma thus a strong clinical suspicion, fair understanding of the pathophysiology, and management of this drug-related complication can prevent fatal outcome...
September 2017: Indian Journal of Psychological Medicine
keyword
keyword
81544
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"