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https://www.readbyqxmd.com/read/27918949/an-exploration-of-metacognitive-beliefs-and-thought-control-strategies-in-bipolar-disorder
#1
Tiril Østefjells, Ingrid Melle, Sofie R Aminoff, Tone Hellvin, Roger Hagen, Trine Vik Lagerberg, June Ullevoldsæter Lystad, Jan Ivar Røssberg
BACKGROUND: Metacognitive factors influence depression, but are largely unexplored in bipolar disorders. We examined i) differences in metacognitive beliefs and thought control strategies between individuals with bipolar disorder and controls, and ii) to what extent clinical characteristics were related to levels of metacognitive beliefs and thought control strategies in bipolar disorder. METHOD: Eighty patients with bipolar disorder were assessed for age at onset of affective disorder, number of affective episodes, symptoms of mania and depression, metacognitive beliefs (MCQ-30) and thought control strategies (TCQ)...
November 23, 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27914864/serum-dhea-s-concentration-correlates-with-clinical-symptoms-and-neurocognitive-function-in-patients-with-bipolar-ii-disorder-a-case-controlled-study
#2
Sheng-Yu Lee, Liang-Jen Wang, Cheng-Ho Chang, Chih-Ching Wu, Hsing-Ling Chen, Shih-Hsien Lin, Chin-Liang Chu, Ti Lu, Ru-Band Lu
OBJECTIVES: Dysregulation of the neuroendocrine system including dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and pregnenolone may play a role in the pathophysiology of bipolar II disorder (BP-II). The aims of the current study are to determine (a) the differences in DHEA, DHEA-S and pregnenolone in patients with BP-II and controls; and (b) the correlation of levels of the above hormones, cognitive function, and clinical symptoms. METHODS: Patients diagnosed with BP-II and healthy controls were recruited from psychiatric department...
November 30, 2016: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27900218/a-prospective-randomised-controlled-study-comparing-bipolar-plasma-vaporisation-of-the-prostate-to-monopolar-transurethral-resection-of-the-prostate
#3
Ahmed M Elsakka, Hssan H Eltatawy, Khaled H Almekaty, Ahmed R Ramadan, Tarik A Gameel, Yasser Farahat
OBJECTIVES: To compare the safety and efficacy of bipolar transurethral plasma vaporisation (B-TUVP) as an alternative to the 'gold standard' monopolar transurethral resection of the prostate (M-TURP) for the treatment of benign prostatic hyperplasia (BPH) in a prospective randomised controlled study. PATIENTS AND METHODS: In all, 82 patients indicated for prostatectomy were assigned to two groups, group I (40 patients) underwent B-TUVP and group II (42 patients) underwent M-TURP...
December 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27890741/perisylvian-gaba-levels-in-schizophrenia-and-bipolar-disorder
#4
Murat İlhan Atagün, Elif Muazzez Şıkoğlu, Çağlar Soykan, Can Serdar Süleyman, Semra Ulusoy-Kaymak, Ali Çayköylü, Oktay Algın, Mary Louise Phillips, Dost Öngür, Constance Mary Moore
The aim of this study is to measure GABA levels of perisylvian cortices in schizophrenia and bipolar disorder patients, using proton magnetic resonance spectroscopy ((1)H-MRS). Patients with schizophrenia (n=25), bipolar I disorder (BD-I; n=28) and bipolar II disorder (BD-II; n=20) were compared with healthy controls (n=30). (1)H-MRS data was acquired using a Siemens 3T whole body scanner to quantify right and left perisylvian structures' (including superior temporal lobes) GABA levels. Right perisylvian GABA values differed significantly between groups [χ(2)=9...
November 24, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27889599/patatin-like-phospholipase-domain-containing-protein-3-pnpla3-a-potential-role-in-the-association-between-liver-disease-and-bipolar-disorder
#5
Aileen Kenneson, Jennifer S Funderburk
OBJECTIVE: Due to the increased prevalence of liver disease in patients with bipolar disorder, we examined the potential role of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant among individuals with bipolar disorder and those with no mood disorder. METHODS: We used the National Health and Nutrition Examination Survey (NHANES) database (aged 15-39 years) to identify a group of individuals with a bipolar diagnosis and a control group of individuals with no mood disorder...
November 22, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27886578/kynurenic-acid-and-psychotic-symptoms-and-personality-traits-in-twins-with-psychiatric-morbidity
#6
Magdalena E Kegel, Viktoria Johansson, Lennart Wetterberg, Maria Bhat, Lilly Schwieler, Tyrone D Cannon, Ina Schuppe-Koistinen, Göran Engberg, Mikael Landén, Christina M Hultman, Sophie Erhardt
Increased cytokines and kynurenic acid (KYNA) levels in cerebrospinal fluid (CSF) have been reported in patients with schizophrenia and bipolar disorder. The aim of the present study was to investigate cytokines and kynurenines in the CSF of twin pairs discordant for schizophrenia or bipolar disorder and to study these CSF markers in relation to psychotic symptoms and personality traits. CSF levels of tryptophan (TRP), KYNA, quinolinic acid (QUIN), interleukin (IL)-6, IL-8 and tumor necrosis factor-alpha (TNF-α) were analyzed in 23 twins with schizophrenia or bipolar disorder, and in their not affected co-twins...
November 16, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27881437/casein-kinase-ii-is-required-for-proper-cell-division-and-acts-as-a-negative-regulator-of-centrosome-duplication-in-c-elegans-embryos
#7
Jeffrey C Medley, Megan M Kabara, Michael D Stubenvoll, Lauren E DeMeyer, Mi Hye Song
Centrosomes are the primary microtubule-organizing centers that orchestrate microtubule dynamics during the cell cycle. The correct number of centrosomes is pivotal for establishing bipolar mitotic spindles that ensure accurate segregation of chromosomes. Thus, centrioles must duplicate once per cell cycle, one daughter per mother centriole, the process of which requires highly coordinated actions among core factors and modulators. Protein phosphorylation is shown to regulate the stability, localization and activity of centrosome proteins...
November 23, 2016: Biology Open
https://www.readbyqxmd.com/read/27872258/bipolar-at-risk-criteria-an-examination-of-which-clinical-features-have-optimal-utility-for-identifying-youth-at-risk-of-early-transition-from-depression-to-bipolar-disorders
#8
Jan Scott, Steven Marwaha, Aswin Ratheesh, Iain Macmillan, Alison R Yung, Richard Morriss, Ian B Hickie, Andreas Bechdolf
BACKGROUND: A clinical and research challenge is to identify which depressed youth are at risk of "early transition to bipolar disorders (ET-BD)." This 2-part study (1) examines the clinical utility of previously reported BD at-risk (BAR) criteria in differentiating ET-BD cases from unipolar depression (UP) controls; and (2) estimates the Number Needed to Screen (NNS) for research and general psychiatry settings. METHODS: Fifty cases with reliably ascertained, ET-BD I and II cases were matched for gender and birth year with 50 UP controls who did not develop BD over 2 years...
November 21, 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/27871641/longitudinal-course-of-bipolar-disorder-in-youth-with-high-functioning-autism-spectrum-disorder
#9
Xenia Borue, Carla Mazefsky, Brian T Rooks, Michael Strober, Martin B Keller, Heather Hower, Shirley Yen, Mary Kay Gill, Rasim S Diler, David A Axelson, Benjamin I Goldstein, Tina R Goldstein, Neal Ryan, Fangzi Liao, Jeffrey I Hunt, Daniel P Dickstein, Boris Birmaher
OBJECTIVE: To provide the first longitudinal characterization of mood and psychosocial functioning in youth with comorbid bipolar (BD) and autism spectrum (ASD) disorders. METHOD: The Course and Outcome of Bipolar Youth study followed 368 youth (aged 7-17 years) with DSM-IV bipolar I (BP-I), BP-II, or Not Otherwise Specified (NOS) for, on average, 9 years using the Longitudinal Interval Follow-up Evaluation. This subgroup analysis compared youth with and without ASD on clinical presentation, percentage of time with mood symptomatology, and psychosocial functioning...
December 2016: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27871636/correlates-of-overweight-and-obesity-among-adolescents-with-bipolar-disorder-in-the-national-comorbidity-survey-adolescent-supplement-ncs-a
#10
Benjamin I Goldstein, Carlos Blanco, Jian-Ping He, Kathleen Merikangas
OBJECTIVE: Despite substantial evidence on the prevalence and correlates of overweight and obesity (OW/OB) in adults with bipolar disorder (BD), little is known about this topic in adolescents with BD. METHOD: The method consisted of the National Comorbidity Survey-Adolescent Supplement, a face-to-face survey of mental disorders from 2001 through 2004, using a modified version of the fully structured World Health Organization Composite International Diagnostic Interview...
December 2016: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27858964/evidence-for-clinical-progression-of-unipolar-and-bipolar-disorders
#11
REVIEW
L V Kessing, P K Andersen
OBJECTIVE: It is a widely held belief that affective disorders are progressive of nature; however, some recent reviews have questioned this belief. The objective of the present systematic literature review was to present evidence for associations between number of affective episodes and (i) the risk of recurrence of episodes, (ii) probability of recovery from episodes, (iii) severity of episodes, (iv) the threshold for developing episodes, and (v) progression of cognitive deficits in unipolar and bipolar disorders...
November 10, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27855101/long-term-cost-effectiveness-of-collaborative-care-vs-usual-care-for-people-with-depression-and-comorbid-diabetes-or-cardiovascular-disease-a-markov-model-informed-by-the-coincide-randomised-controlled-trial
#12
Elizabeth M Camacho, Dionysios Ntais, Peter Coventry, Peter Bower, Karina Lovell, Carolyn Chew-Graham, Clare Baguley, Linda Gask, Chris Dickens, Linda M Davies
OBJECTIVES: To evaluate the long-term cost-effectiveness of collaborative care (vs usual care) for treating depression in patients with diabetes and/or coronary heart disease (CHD). SETTING: 36 primary care general practices in North West England. PARTICIPANTS: 387 participants completed baseline assessment (collaborative care: 191; usual care: 196) and full or partial 4-month follow-up data were captured for 350 (collaborative care: 170; usual care: 180)...
October 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27847590/interhemispheric-functional-disconnection-because-of-abnormal-corpus-callosum-integrity-in-bipolar-disorder-type-ii
#13
Fumihiko Yasuno, Takashi Kudo, Kiwamu Matsuoka, Akihide Yamamoto, Masato Takahashi, Jyoji Nakagawara, Kazuyuki Nagatsuka, Hidehiro Iida, Toshifumi Kishimoto
BACKGROUND: A significantly lower fractional anisotropy (FA) value has been shown in anterior parts of the corpus callosum in patients with bipolar disorder. AIMS: We investigated the association between abnormal corpus callosum integrity and interhemispheric functional connectivity (IFC) in patients with bipolar disorder. METHODS: We examined the association between FA values in the corpus callosum (CC-FA) and the IFC between homotopic regions in the anterior cortical structures of bipolar disorder (n=16) and major depressive disorder (n=22) patients with depressed or euthymic states...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/27846411/binge-eating-disorder-and-bipolar-spectrum-disorders-in-obesity-psychopathological-and-eating-behaviors-differences-according-to-comorbidities
#14
Cristina Segura-Garcia, Mariarita Caroleo, Marianna Rania, Elvira Barbuto, Flora Sinopoli, Matteo Aloi, Franco Arturi, Pasquale De Fazio
BACKGROUND: Obesity is not a mental disorder, yet DSM-5 recognizes a strong association between obesity and psychiatric syndromes. Disorders within the Bipolar Spectrum (BSD) and Binge Eating Disorder (BED) are the most frequent psychiatric disorders among obese patients. The aim of this research is to investigate the psychopathological differences and the distinctive eating behaviors that accompany these comorbidities in obese patients. METHODS: One hundred and nineteen obese patients (40 males; 79 females) underwent psychological evaluation and psychiatric interview, and a dietitian evaluated their eating habits...
November 10, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27826323/bipolar-i-and-ii-disorders-a-systematic-review-and-meta-analysis-on-differences-in-comorbid-obsessive-compulsive-disorder
#15
REVIEW
Andrea Amerio, Brendon Stubbs, Anna Odone, Matteo Tonna, Carlo Marchesi, S Nassir Ghaemi
CONTEXT: More than half of the bipolar disorder (BD) cases have an additional diagnosis; one of the most difficult to manage is obsessive-compulsive disorder (OCD). Although some authors recently investigated the co-occurrence of anxiety and BD, the topic remains insufficiently studied. The current study aimed to investigate differences in comorbid OCD between BD-I and BD-II. EVIDENCE ACQUISITION: A systematic review and meta-analysis was conducted on the prevalence and predictors of comorbid BD-I/BD-II and OCD...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27822276/demographic-and-diagnostic-features-of-3147-inpatients-with-mood-disorders-in-iran
#16
Atefeh Ghanbari Jolfaei, Pari Ghadamgahi, Masoud Ahmadzad-Asl, Amir Shabani
OBJECTIVES: To assess and compare demographic and diagnostic characteristics of inpatients with mood disorders in Iran. MATERIALS AND METHODS: We collected the demographic, clinical, and treatment characteristics of patients, who were hospitalized during five years from April 2006 to March 2010, in Iran hospital of psychiatry, a residency training center to evaluate the general clinical picture of the disorder. RESULTS: Overall, 95.3% of subjects had a diagnosis of bipolar I disorder (BID), 2...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27816324/differences-in-clinical-presentation-between-bipolar-i-and-ii-disorders-in-the-early-stages-of-bipolar-disorder-a-naturalistic-study
#17
Maj Vinberg, Rie Lambaek Mikkelsen, Thomas Kirkegaard, Ellen Margrethe Christensen, Lars Vedel Kessing
AIM: In a naturalistic clinical study of patients in the early stages of bipolar disorders the aim was to assess differences between patients with bipolar I (BD I) and bipolar II (BD II) disorders on clinical characteristics including affective symptoms, subjective cognitive complaints, functional level, the presence of comorbid personality disorders and coping strategies. METHODS: Diagnoses were confirmed using the Structured Clinical Interview for DSM-IV Disorders...
October 25, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27813593/case-report-case-study-of-a-patient-presenting-both-type-ii-bipolar-affective-disorder-and-klinefelter-syndrome
#18
H Delavenne, J M Khoury, F Thibaut, F D Garcia
Klinefelter syndrome (KS) is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000. Increased incidences of anxiety, depression, substance abuse, psychotic and behavioral disorders, and sexual disorders have been reported in patients with KS. The aim of this case study was to report a case of a man with untreated KS who was also diagnosed with type II bipolar disorder. This case report raises awareness regarding psychiatric diagnoses that may be associated with such a highly prevalent condition...
October 17, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27810725/physical-and-mental-health-burden-in-cases-of-bipolar-disorder-classified-as-current-former-or-non-tobacco-smokers
#19
R Icick, S Gard, M Barde, M Carminati, A Desage, S Guillaume, J Scott, F Bellivier
BACKGROUND: Tobacco smoking increases the global burden of bipolar disorder (BD). We examined markers of physical and mental health that are associated with tobacco smoking, controlling for confounders that have not always been considered in previous studies of BD. METHODS: Over 600 individuals with BD I or II referred to the French Network for bipolar disorder (FACE-BD) who completed standardized assessments, and could be reliably classified as current (CS) or former smokers (FS), were compared with those who were never smokers (NS) on: BD symptom load and psychiatric comorbidities; prevalence of alcohol and substance use disorders (ASUD); medication usage; functioning and physical health parameters...
September 23, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27810719/prediction-of-near-term-increases-in-suicidal-ideation-in-recently-depressed-patients-with-bipolar-ii-disorder-using-intensive-longitudinal-data
#20
Colin A Depp, Wesley K Thompson, Ellen Frank, Holly A Swartz
BACKGROUND: There are substantial gaps in understanding near-term precursors of suicidal ideation in bipolar II disorder. We evaluated whether repeated patient-reported mood and energy ratings predicted subsequent near-term increases in suicide ideation. METHODS: Secondary data were used from 86 depressed adults with bipolar II disorder enrolled in one of 3 clinical trials evaluating Interpersonal and Social Rhythm Therapy and/or pharmacotherapy as treatments for depression...
October 18, 2016: Journal of Affective Disorders
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