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https://www.readbyqxmd.com/read/28433088/parental-age-and-offspring-psychopathology-in-the-philadelphia-neurodevelopmental-cohort
#1
Alison K Merikangas, Monica E Calkins, Warren B Bilker, Tyler M Moore, Ruben C Gur, Raquel E Gur
OBJECTIVE: Increasing evidence implicates advanced paternal age at offspring birth in neuropsychiatric disorders. Advanced maternal age has also been associated with schizophrenia and other neurodevelopmental disorders, whereas younger maternal age has been linked with behavioral disorders. Few studies have considered the specificity of the associations with respect to comorbidity. In addition, most prior studies have been conducted in clinical samples or registries that may reflect more severe forms of psychopathology...
May 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28428742/a-set-based-mixed-effect-model-for-gene-environment-interaction-and-its-application-to-neuroimaging-phenotypes
#2
Changqing Wang, Jianping Sun, Bryan Guillaume, Tian Ge, Derrek P Hibar, Celia M T Greenwood, Anqi Qiu
Imaging genetics is an emerging field for the investigation of neuro-mechanisms linked to genetic variation. Although imaging genetics has recently shown great promise in understanding biological mechanisms for brain development and psychiatric disorders, studying the link between genetic variants and neuroimaging phenotypes remains statistically challenging due to the high-dimensionality of both genetic and neuroimaging data. This becomes even more challenging when studying gene-environment interaction (G×E) on neuroimaging phenotypes...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28427766/evaluation-of-a-model-of-integrated-care-for-patients-with-chronic-medical-and-psychiatric-illness
#3
Aghaegbulam Uga, Shreedhar Kulkarni, Vineka Heeramun, Kathy Bottum
BACKGROUND: Chronic illnesses are prevalent in general medical and psychiatric practices, causing significant disease burden to care givers and providers. Systems of care that treat individuals with mental illness are often separate from general medical systems of care. OBJECTIVE: This study sought to compare the quality of life, satisfaction with care, and utilization of care in patients with comorbid chronic medical and mental illnesses. METHODS: A total of 64 participants from an integrated medicine and psychiatry clinic (med/psych), were compared with 52 patients from separate internal medicine and psychiatry clinics (within the same institution) for quality of life, satisfaction with care, and utilization of care...
February 20, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28427559/stress-induced-nlrp3-inflammasome-in-human-diseases
#4
Elísabet Alcocer-Gómez, Beatriz Castejón-Vega, Mario D Cordero
Stress is a complex event that induces disturbances to physiological and psychological homeostasis, and it may have a detrimental impact on certain brain and physiological functions. In the last years, a dual role of the stress effect has been studied in order to elucidate the molecular mechanism by which can induce physiological symptoms after psychological stress exposition and vice versa. In this sense, inflammation has been proposed as an important starring. And in the same line, the inflammasome complex has emerged to give responses because of its role of stress sensor...
2017: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/28426367/child-and-adolescent-emergency-and-urgent-mental-health-delivery-through-telepsychiatry-12-month-prospective-study
#5
Nasreen Roberts, Tina Hu, Nicholas Axas, Leanne Repetti
BACKGROUND: The significant gap between children and adolescents presenting for emergency mental healthcare and the shortage of child and adolescent psychiatrists constitutes a major barrier to timely access for psychiatric assessment for rural and remote areas. Unlike remote areas, urban emergency departments have in-house psychiatric consultation. Telepsychiatry may be a solution to ensure the same service for remote areas. However, there is a paucity of studies on the use of telepsychiatry for child and adolescent emergency consults...
April 20, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28424045/a-modified-mediterranean-dietary-intervention-for-adults-with-major-depression-dietary-protocol-and-feasibility-data-from-the-smiles-trial
#6
Rachelle S Opie, Adrienne O'Neil, Felice N Jacka, Josephine Pizzinga, Catherine Itsiopoulos
BACKGROUND: The SMILES trial was the first randomized controlled trial (RCT) explicitly designed to evaluate a dietary intervention, conducted by qualified dietitians, for reducing depressive symptomatology in adults with clinical depression. OBJECTIVES: Here we detail the development of the prescribed diet (modified Mediterranean diet (ModiMedDiet)) for individuals with major depressive disorders (MDDs) that was designed specifically for the SMILES trial. We also present data demonstrating the extent to which this intervention achieved improvements in diet quality...
April 19, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28421479/understanding-medical-students-experience-with-stress-and-its-related-constructs-a-focus-group-study-from-singapore
#7
Julia Farquhar, Desiree Lie, Angelique Chan, Mandy Ow, Arpana Vidyarthi
OBJECTIVE: In order to protect medical students from burnout and its untoward psychiatric effects, it is imperative to understand their stress, burnout, coping, and resilience experiences. This study aimed to derive collective definitions from the medical student perspective, to identify common themes of students' experiences, and to distinguish pre-clinical and clinical year students' experiences relating to these four constructs. METHODS: The authors conducted focus groups of medical students in Singapore across 4 years using a semi-structured question guide...
April 18, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28417648/danish-translation-and-validation-of-kessler-s-10-item-psychological-distress-scale-k10
#8
Camilla Thelin, Benjamin Mikkelsen, Gunnar Laier, Louise Turgut, Bente Henriksen, Lis Raabaek Olsen, Jens Knud Larsen, Sidse Arnfred
BACKGROUND: Psychological distress is a trans-diagnostic feature of mental suffering closely associated with mental disorders. Kessler's 10-item Psychological Distress Scale (K10), a scale with sound psychometric properties, is widely used in epidemiological studies. AIM: To translate and investigate whether K10 is a reliable and valid rating scale for the measurement of psychological distress in a Danish population. METHODS: The translation was carried out according to official WHO translation guidelines...
April 18, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28416810/the-joint-impact-of-cognitive-performance-in-adolescence-and-familial-cognitive-aptitude-on-risk-for-major-psychiatric-disorders-a-delineation-of-four-potential-pathways-to-illness
#9
K S Kendler, H Ohlsson, R S E Keefe, K Sundquist, J Sundquist
How do joint measures of premorbid cognitive ability and familial cognitive aptitude (FCA) reflect risk for a diversity of psychiatric and substance use disorders? To address this question, we examined, using Cox models, the predictive effects of school achievement (SA) measured at age 16 and FCA-assessed from SA in siblings and cousins, and educational attainment in parents-on risk for 12 major psychiatric syndromes in 1 140 608 Swedes born 1972-1990. Four developmental patterns emerged. In the first, risk was predicted jointly by low levels of SA and high levels of FCA-that is a level of SA lower than would be predicted from the FCA...
April 18, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28413938/psychiatric-service-users-experiences-of-emergency-departments-a-cerqual-review-of-qualitative-studies
#10
Kathrine Carstensen, Stina Lou, Lotte Groth Jensen, Nina Konstantin Nissen, Lisbeth Ortenblad, Margarete Pfau, Pia Vedel Ankersen
BACKGROUND: There is increased clinical and political attention towards integrating general and psychiatric emergency departments (ED). However, research into psychiatric service users' experiences regarding general EDs is limited. AIM: To identify and summarize current, qualitative evidence regarding service users' experiences attending EDs. A secondary aim is to apply and test the newly developed CERQual approach to summarizing qualitative review findings. METHODS: A systematic literature review of five databases based on PRISMA guidelines yielded 3334 unique entries...
May 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28413442/specific-coping-strategies-moderate-the-link-between-emotion-expression-deficits-and-nonsuicidal-self-injury-in-an-inpatient-sample-of-adolescents
#11
Kristel Thomassin, Camille Guérin Marion, Myriam Venasse, Anne Shaffer
BACKGROUND: Non-suicidal self-injury (NSSI) is a behavior of increasing prevalence in adolescents with links to various negative mental health and adjustment outcomes. Poor emotion expression has been linked with NSSI use, whereas the use of adaptive coping strategies has been identified as a protective factor against NSSI. The current study examined whether specific coping strategies moderate the relation between poor emotion expression and NSSI, and whether moderation is conditional on adolescent gender...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28413438/a-case-report-of-brief-psychotic-disorder-with-catalepsy-associated-with-sequential-life-threatening-events-in-a-patient-with-advanced-cancer
#12
Mayumi Ishida, Satoshi Kawada, Hideki Onishi
BACKGROUND: Cancer is commonly perceived as life-threatening and universally stressful; however, brief psychotic disorder, which occurs in response to extremely stressful events, has not been reported. CASE PRESENTATION: A 63-year-old woman, who was diagnosed as having pancreatic cancer with liver metastasis, became unresponsive with very little reaction to verbal contact after sequential life-threatening events, such as thrombosis of both pulmonary arteries and stenosis of the third portion of the duodenum, due to disease progression over 3 weeks beginning with oncological emergency hospital admission...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28411665/-the-nursing-care-of-a-suicidal-patient
#13
Harold Simon, Grégory Mykolow, Josselin Guyodo
The management of a suicidal crisis falls within the scope of nursing care. There is a high rate of recurrence in the months following an attempted suicide. The nurse monitoring strategy, based on the principle of the 'recontacting' of patients, has been tested by the team of a post-emergency psychiatric unit of a university hospital.
April 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28411560/comparison-between-the-who-and-niaaa-criteria-for-binge-drinking-on-drinking-features-and-alcohol-related-aftermaths-results-from-a-cross-sectional-study-among-eight-emergency-wards-in-france
#14
Benjamin Rolland, Ingrid de Chazeron, Françoise Carpentier, Fares Moustafa, Alain Viallon, Xavier Jacob, Patrick Lesage, Delphine Ragonnet, Annick Genty, Julie Geneste, Emmanuel Poulet, Maurice Dematteis, Pierre-Michel Llorca, Mickaël Naassila, Georges Brousse
BACKGROUND: Binge drinking (BD) consists of heavy episodic alcohol use. Whereas the World Health Organization (WHO) defines BD as 60g of alcohol or more per occasion, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) conceives BD as drinking 70g (men) or 56g (women) in less than two hours. We compared the subjects delineated by each definition. METHODS: Eight-center cross-sectional study among 11,695 subjects hospitalized in emergency wards. Participants completed the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C), CAGE and Rapid Alcohol Problem Screen 4 (RAPS4-QF) questionnaires...
March 23, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28410824/treated-and-released-urinary-catheterization-in-the-emergency-department-by-sex
#15
Scott Martin Vouri, Margaret A Olsen, Daniel Theodoro, Seth A Strope
BACKGROUND: The prevalence and difference in likely indications of urinary catheterization (UC) in treated-and-released emergency department (ED) visits between men and women are currently unknown. METHODS: This was a cross-sectional analysis using the 2013 National Emergency Department Sample for all treated-and-released visits in persons aged ≥18 years. The prevalence of conditions associated with UC visits in men and women were identified. A hierarchical ranking was used to categorize diagnosis codes identified during ED visits into clinically meaningful categories to assess conditions for UC...
April 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28410563/wernicke-s-encephalopathy-following-reduced-food-intake-due-to-depressive-disorders
#16
Donato Melchionda, Tommaso Martino, Elena Carapelle, Alessandra Lalla, Daniela Cologno, Carlo Avolio
Wernicke's encephalopathy (WE) is an unexpected common neurological disorder caused by thiamine deficiency often due to alcohol abuse, but WE-not alcohol related is also frequent. A prolonged reduction of food intake can cause WE. This condition can arise in depression disorders, especially in the early stages of these psychiatric syndromes. WE is characterized by the triad of signs: ataxia, ocular dysfunctions and confusional state. However, they rarely appear together and this makes the diagnosis particularly difficult, especially when there is not a history of alcohol abuse...
April 14, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28407748/the-role-of-ethnicity-in-pathways-to-emergency-psychiatric-services-for-clients-with-psychosis
#17
Martin Rotenberg, Andrew Tuck, Rachel Ptashny, Kwame McKenzie
BACKGROUND: This study investigates the role of ethnicity in pathways to emergency mental health care in Toronto for clients with psychosis, while taking into account neighborhood factors. Previous literature has focused on Afro-Caribbean clients, reporting an increased risk of accessing mental health care through negative pathways. METHODS: A retrospective chart review for clients from 6 different ethnic origin groups presenting with psychosis - East Asian, South Asian, Black African, Black Caribbean, White European, and White North American - was undertaken in a psychiatric emergency department (ED)...
April 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28402333/maoa-a-novel-decision-maker-of-apoptosis-and-autophagy-in-hormone-refractory-neuroendocrine-prostate-cancer-cells
#18
Yi-Cheng Lin, Yi-Ting Chang, Mel Campbell, Tzu-Ping Lin, Chin-Chen Pan, Hsin-Chen Lee, Jean C Shih, Pei-Ching Chang
Autophagy and apoptosis are two well-controlled mechanisms regulating cell fate. An understanding of decision-making between these two pathways is in its infancy. Monoamine oxidase A (MAOA) is a mitochondrial enzyme that is well-known in psychiatric research. Emerging reports showed that overexpression MAOA is associated with prostate cancer (PCa). Here, we show that MAOA is involved in mediating neuroendocrine differentiation of PCa cells, a feature associated with hormone-refractory PCa (HRPC), a lethal type of disease...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28401275/dimensionality-of-dsm-5-posttraumatic-stress-disorder-and-its-association-with-suicide-attempts-results-from-the-national-epidemiologic-survey-on-alcohol-and-related-conditions-iii
#19
Chiung M Chen, Young-Hee Yoon, Thomas C Harford, Bridget F Grant
BACKGROUND: Emerging confirmatory factor analytic (CFA) studies suggest that posttraumatic stress disorder (PTSD) as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) is best characterized by seven factors, including re-experiencing, avoidance, negative affect, anhedonia, externalizing behaviors, and anxious and dysphoric arousal. The seven factors, however, have been found to be highly correlated, suggesting that one general factor may exist to explain the overall correlations among symptoms...
April 11, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28401046/functional-neuroanatomy-in-panic-disorder-status-quo-of-the-research
#20
Thomas Sobanski, Gerd Wagner
AIM: To provide an overview of the current research in the functional neuroanatomy of panic disorder. METHODS: Panic disorder (PD) is a frequent psychiatric disease. Gorman et al (1989; 2000) proposed a comprehensive neuroanatomical model of PD, which suggested that fear- and anxiety-related responses are mediated by a so-called "fear network" which is centered in the amygdala and includes the hippocampus, thalamus, hypothalamus, periaqueductal gray region, locus coeruleus and other brainstem sites...
March 22, 2017: World Journal of Psychiatry
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