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https://www.readbyqxmd.com/read/29159447/transcriptome-sequencing-of-the-long-nosed-bandicoot-perameles-nasuta-reveals-conservation-and-innovation-of-immune-genes-in-the-marsupial-order-peramelemorphia
#1
Katrina M Morris, Haylee J Weaver, Denis O'Meally, Marion Desclozeaux, Amber Gillett, Adam Polkinghorne
Bandicoots are omnivorous marsupials of the order Peramelemorphia. Conservation concerns and their unique biological characteristics suggest peramelomorphs are worthy research subjects, but knowledge of their genetics and immunology has lagged behind that of other high-profile marsupials. Here, we characterise the transcriptome of the long-nose bandicoot (Perameles nasuta), the first high-throughput data set from any peramelomorph. We investigate the immune gene repertoire of the bandicoot, with a focus on key immune gene families, and compare to previously characterised marsupial and mammalian species...
November 20, 2017: Immunogenetics
https://www.readbyqxmd.com/read/29152923/editorial-in-bed-with-the-devil-recognizing-human-teratogenic-exposures
#2
EDITORIAL
Jan M Friedman
No abstract text is available yet for this article.
November 1, 2017: Birth defects research
https://www.readbyqxmd.com/read/29150526/the-devil-is-in-the-domain-understanding-protein-recognition-of-multiple-rna-targets
#3
REVIEW
Glen R Gronland, Andres Ramos
RNA regulation provides a finely tuned and highly co-ordinated control of gene expression. Regulation is mediated by hundreds to thousands of multi-functional RNA-binding proteins which often interact with large sets of RNAs. In this brief review, we focus on a recent work that highlights how the proteins use multiple RNA-binding domains to interact selectively with the different RNA targets. Deconvoluting the molecular complexity of the RNA regulatory network is essential to understanding cell differentiation and function, and requires accurate models for protein-RNA recognition and protein target selectivity...
November 17, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/29149677/effects-of-deslorelin-implants-on-reproduction-and-feeding-behavior-in-tasmanian-devils-sarcophilus-harrisii-housed-in-free-range-enclosures
#4
Holly R Cope, Carolyn J Hogg, Karen Fagg, Olivia Barnard, Peter J White, Catherine A Herbert
In captive breeding programs, it is becoming increasingly important to maximize the retention of genetic diversity by managing the reproductive contribution of each individual, which can be facilitated through the use of selective contraception. This becomes critical when captive populations are held for several generations, and managers must prevent the confines of housing space and financial support from compromising genetic integrity. For example, the Tasmanian devil insurance population, established in 2006, is strategically managed to equalize founder representation...
November 4, 2017: Theriogenology
https://www.readbyqxmd.com/read/29149421/kribbella-podocarpi-sp-nov-isolated-from-the-leaves-of-a-yellowwood-tree-podocarpus-latifolius
#5
Sarah M Curtis, Iulia Norton, Gareth J Everest, Paul R Meyers
An endophytic actinobacterial strain was isolated from a yellowwood tree growing on the slope of Devil's Peak, Cape Town, South Africa. Analysis of the 16S rRNA gene showed that the strain belongs to the genus Kribbella. Phylogenetic analyses using the 16S rRNA gene and multilocus sequence analysis using the concatenated gene sequences of the gyrB, rpoB, relA, recA and atpD genes showed that strain YPL1(T) is closely related to the type strains of Kribbella karoonensis and Kribbella shirazensis. DDH experiments showed that strain YPL1(T) is a distinct genomic species from its close phylogenetic relative, K...
November 17, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29148600/new-evidence-for-the-recent-divergence-of-devil-s-hole-pupfish-and-the-plausibility-of-elevated-mutation-rates-in-endangered-taxa
#6
Christopher H Martin, Sebastian Höhna
Saglam et al. (2016) recently argued that the Devil's Hole Pupfish (Cyprinodon diabolis), a conservation icon with the smallest known species range, was isolated 60 kya based on a new genomic dataset. If true, this would be a radically long timescale for any species to persist at population sizes less than 500 individuals, in contrast to conservation genetics theory. However, here we argue that their analyses and interpretation are inappropriate. They placed highly restrictive prior distributions on divergence times, which do not appropriately model the large uncertainty and result in removing nearly all uncertainty from their analyses, and chose among models by assuming that pupfishes exhibit human mutation rates...
November 17, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29121323/diastolic-dysfunction-and-sepsis-the-devil-is-in-the-detail
#7
J Poelaert
No abstract text is available yet for this article.
October 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29118585/pain-management-prescription-opioid-mortality-and-the-cdc-is-the-devil-in-the-data
#8
EDITORIAL
Michael E Schatman, Stephen J Ziegler
No abstract text is available yet for this article.
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29114954/maldistribution-or-scarcity-of-nurses-the-devil-is-in-the-detail
#9
Jitske M C Both-Nwabuwe, Maria T M Dijkstra, Ab Klink, Bianca Beersma
AIMS: The goal of this paper was to improve our understanding of nursing shortages across the variety of health care sectors and how this may affect the agenda for addressing nursing shortages. A health care sector comprises a number of health care services for one particular type of patient care, for example, the hospital care sector. BACKGROUND: Most Western countries are shifting health care services from hospital care towards community and home care, thus increasing nursing workforce challenges in home and community care...
November 7, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/29108476/intermittent-catheterization-the-devil-is-in-the-details
#10
Kathleen Christison, Matthias Walter, Jean-Jacques J M Wyndaele, Michael Kennelly, Thomas M Kessler, Vanessa K Noonan, Nader Fallah, Andrei V Krassioukov
During the last few years, the international community debated on urinary tract infection and re-use of catheters when managing neurogenic lower urinary tract dysfunction among individuals with SCI. In this respect, the 2014 Cochrane review by Prieto et al, 'Intermittent Catheterisation for Long-Term Bladder Management', became one of the leading documents that captured mind and attention of clinicians around the world. Although numerous countries switched to single-use catheters as guidelines for management of bladder following SCI, the opinion that was expressed in the 2014 Cochrane review had a strong influence on healthcare providers and agencies to recommend re-use of catheters...
November 6, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29061568/r-chop-14-with-or-without-radiotherapy-in-non-bulky-limited-stage-diffuse-large-b-cell-lymphoma-dlbcl
#11
Thierry Lamy, Gandhi Damaj, Pierre Soubeyran, Emmanuel Gyan, Guillaume Cartron, Krimo Bouabdallah, Rémy Gressin, Jérôme Cornillon, Anne Banos, Katell Le Du, Mohamed Benchalal, Marie-Pierre Moles, Steven Le Gouill, Joel Fleury, Pascal Godmer, Hervé Maisonneuve, Eric Deconinck, Roch Houot, Kamel Laribi, Jean Pierre Marolleau, Olivier Tournilhac, Bernard Branger, Anne Devillers, Jean Philippe Vuilliez, Thierry Fest, Philippe Colombat, Valérie Costes, Vanessa Szablewski, Marie C Béné, Vincent Delwail
The benefit of radiotherapy (RT) following chemotherapy in limited-stage diffuse large B-cell lymphoma (DLBCL) remains controversial. Before the Rituximab (R) era, randomized trials have reported conflicting results. We conducted a randomized trial in patients with non-bulky (tumor size <7cm) limited-stage DLBCL to evaluate the benefit of RT following R-CHOP. Patients were stratified according to the Miller modified IPI (mIPI) including LDH (normal/elevated), ECOG performance status (0-1/2-3), age (<60/>60 yrs) and disease stage (I/II)...
October 23, 2017: Blood
https://www.readbyqxmd.com/read/29055787/occurrence-of-a-stonefish-toxin-like-toxin-in-the-venom-of-the-rabbitfish-siganus-fuscescens
#12
Aya Kiriake, Shoichiro Ishizaki, Yuji Nagashima, Kazuo Shiomi
Rabbitfish belonging to the order Perciformes are well-known venomous fish that are frequently involved in human accidents. However little research has been done into either the whole venom toxicities or the structures and properties of their venom toxins. In this study, we first examined biological activities of the crude venom extract prepared from dorsal spines of Siganus fuscescens, a rabbitfish most commonly found along the coasts of Japan. As a result, the crude venom extract was shown to have mouse-lethal activity, hemolytic activity against rabbit erythrocytes, edema-forming activity and nociceptive activity, similar to the known scorpaeniform fish toxins (stonefish toxins and their analogues)...
October 18, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29052920/treatment-doses-in-idiopathic-pulmonary-fibrosis-the-devil-is-in-the-detail
#13
EDITORIAL
Athol U Wells, Katerina M Antoniou
No abstract text is available yet for this article.
October 20, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29052429/idle-minds-are-the-devil-s-tools-coping-depressed-mood-and-divergent-thinking-in-older-adults
#14
Juan Carlos Mélendez, Vicente Alfonso-Benlliure, Teresa Mayordomo
OBJECTIVES: The main aim was to test a causal relations model of the problem-focused and emotion-focused coping styles, depressed mood, and divergent thinking (DT) in older adults. It was hypothesized that both forms of coping would have a significant effect on predicting depressed mood, and that problem-focused coping and depressed mood would have a significant effect on DT. METHOD: Participants were 135 subjects with ages ranging between 55 and 84 years old, who took part in a personal interview and filled out several questionnaires...
October 20, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29051345/reply-utilizing-and-interpreting-fdg-pet-ct-images-in-patients-referred-for-assessment-of-cardiac-sarcoidosis-the-devil-is-in-the-details
#15
David Birnie, Hiroshi Ohira, Rob Beanlands
No abstract text is available yet for this article.
October 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29047125/how-to-describe-your-data-the-devil-is-in-the-distribution
#16
S W Choi, D M H Lam
No abstract text is available yet for this article.
November 2017: Anaesthesia
https://www.readbyqxmd.com/read/29037291/the-devil-we-know-is-the-use-of-injectable-agents-for-the-treatment-of-mdr-tb-justified
#17
A Reuter, P Tisile, D von Delft, H Cox, V Cox, L Ditiu, A Garcia-Prats, S Koenig, E Lessem, R Nathavitharana, J A Seddon, J Stillo, A von Delft, J Furin
For decades, second-line injectable agents (IAs) have been the cornerstone of treatment for multidrug-resistant tuberculosis (MDR-TB). Although evidence on the efficacy of IAs is limited, there is an expanding body of evidence on the serious adverse events caused by these drugs. Here, we present the results of a structured literature review of the safety and efficacy of IAs. We review the continued widespread use of these agents in the context of therapeutic alternatives-most notably the newer TB drugs, bedaquiline and delamanid-and from the context of human rights, ethics and patient-centered care...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29035158/humanizing-folk-devils-using-ethnography
#18
Peter L Myers
The sociological concepts of the "moral panic" and the deviant "folk devil" apply to the drug panics in the United States over methamphetamine, heroin, and crack cocaine. Mothers or pregnant women who smoke crack cocaine, and their babies, are assigned exaggerated "demonic" attributes that result in stigma and societal rejection. Otherwise, ethnographic studies of drug users demonstrate realities that are other than what might be considered were one to merely look at their use and the consequences. These considerations are examined with respect to the image of folk devils, methadone program attendees, smokers of "blunts," opium den habitués, and others grouped together as negative influences as a result of their drug habits...
October 16, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29027322/inotropes-and-vasopressors-in-acute-heart-failure-when-the-devil-dresses-as-an-angel
#19
EDITORIAL
Andrea Mortara
No abstract text is available yet for this article.
October 12, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29026944/improving-elution-strategies-for-chelex%C3%A2-dgt-passive-samplers
#20
Delphine Devillers, Rémy Buzier, Adeline Charriau, Gilles Guibaud
Elution of Chelex® binding layers, commonly used for the diffusive gradients in thin films technique (DGT), is recognized as the most important contributor to the uncertainty of DGT measurements. Limiting uncertainty requires the use of optimized procedures and suitable elution recoveries (f e ). This work therefore investigated elution robustness to propose improved strategies. A wide range of conditions were investigated for the main elution parameters (Chelex® particle size, elution time, Chelex® loading, and eluent concentration and volume) on Al(III), Cd(II), Co(II), Cr(III), Cu(II), Ni(II), Pb(II), and Zn(II)...
October 12, 2017: Analytical and Bioanalytical Chemistry
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