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https://www.readbyqxmd.com/read/28717758/organization-of-chemotherapy-and-systemic-therapy-services-in-india-the-devil-lies-in-the-details
#1
Sameer Rastogi, Aditi Aggarwal
No abstract text is available yet for this article.
April 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28704749/key-role-of-the-sorption-process-in-alteration-of-metal-and-metalloid-quantification-by-fouling-development-on-dgt-passive-samplers
#2
Delphine Devillers, Rémy Buzier, Malgorzata Grybos, Adeline Charriau, Gilles Guibaud
The DGT technique (diffusive gradients in thin films) is widely used for passive sampling of labile trace metals and metalloids in natural waters. Although development of fouling on the protective membranes is frequently observed, its effect on DGT sampling has been barely investigated. This study evaluates the influence of fouling on sampling of trace cationic metals Cd(II), Cu(II), Ni(II) and Pb(II) and oxyanions As(V), Cr(VI), Sb(V) and Se(VI). Fouling was developed in situ on polycarbonate membranes in four diverse natural freshwater environments and sampling alteration was assessed in controlled laboratory experiments...
July 10, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28699506/natural-or-plant-products-for-the-treatment-of-neurological-disorders-current-knowledge
#3
Mohammad Khalid Parvez
In recent decades, complementary and alternative medicine (CAM) has become very popular in the treatment of several chronic diseases. Natural products as one of the CAM modalities offer potential opportunities to discover lead compounds for novel drug development. The use of CAM or natural products in the prevention of neurodegenerative diseases is comparatively a newer area. Natural therapeutics with anti-oxidative and anti-inflammatory salutations evidently plays a crucial role in protecting neurons. Of these, the most promising are caffeine, trigonelline, shogaol, curcumin, resveratrol, baicalein, wogonin, ginsenosides, tanshinones, withanolides, picrosides, parthenolide, cannabinoids, Devil's claw and white willow bark, including Chinese formulations Renshen Shouwu and Shengmai San...
July 10, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28695294/the-role-of-mhc-genes-in-contagious-cancer-the-story-of-tasmanian-devils
#4
REVIEW
Alison Caldwell, Hannah V Siddle
The Tasmanian devil, a marsupial species endemic to the island of Tasmania, harbours two contagious cancers, Devil Facial Tumour 1 (DFT1) and Devil Facial Tumour 2 (DFT2). These cancers pass between individuals in the population via the direct transfer of tumour cells, resulting in the growth of large tumours around the face and neck of affected animals. While these cancers are rare, a contagious cancer also exists in dogs and five contagious cancers circulate in bivalves. The ability of tumour cells to emerge and transmit in mammals is surprising as these cells are an allograft and should be rejected due to incompatibility between Major Histocompatibility Complex (MHC) genes...
July 11, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28689773/the-toll-like-receptor-ligands-hiltonol-%C3%A2-polyiclc-and-imiquimod-effectively-activate-antigen-specific-immune-responses-in-tasmanian-devils-sarcophilus-harrisii
#5
Amanda L Patchett, Cesar Tovar, Lynn M Corcoran, A Bruce Lyons, Gregory M Woods
Devil facial tumour disease (DFTD) describes two genetically distinct transmissible tumours that pose a significant threat to the survival of the Tasmanian devil. A prophylactic vaccine could protect devils from DFTD transmission. For this vaccine to be effective, potent immune adjuvants will be required. Toll-like receptors (TLRs) promote robust immune responses in human cancer studies and are highly conserved across mammalian species. In this study, we investigated the proficiency of TLR ligands for immune activation in the Tasmanian devil using in vitro mononuclear cell stimulations and in vivo immunisation trials with a model antigen...
July 6, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28683993/the-dance-of-2-devils-mitral-valve-repair-and-functional-mitral-stenosis
#6
EDITORIAL
Bobby Yanagawa, Vincent Chan, Subodh Verma
No abstract text is available yet for this article.
April 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28683871/the-devil-is-in-the-details-failure-to-cap-or-scrub-the-hub-can-lead-to-infection-control-risks
#7
Susan F Paparella
No abstract text is available yet for this article.
July 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/28671777/-cutaneous-infections-in-the-emergency-department-the-devil-in-the-detail
#8
Ioanna Chrysogelou, Olivier Clerc, Vincent Della Santa
Skin and soft tissue infections, which are a common cause of admission, are characterized by a clinical polymorphism leading to diagnostic errors. To a certain point, confusion exists between used terms and indicated treatment, especially since the emergence of methicillin-resistant Staphylococcus aureus (MRSA) infections.The paucity of cutaneous findings early in the course of deep soft tissue infections makes diagnosis challenging for physicians in charge. Some of these infections are warranted to achieve a lower mortality and morbidity by the administration of effective surgical treatment...
August 10, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28670660/memory-t-cells-in-type-1-diabetes-the-devil-is-in-the-detail
#9
REVIEW
Aditi Narsale, Joanna D Davies
PURPOSE OF REVIEW: Therapies that target beta-cell antigen-specific T cells subsets have not been as successful in patients with type 1 diabetes as in mice. This might be explained by complexities in the repertoire of beta-cell antigen-specific T cells and the variety of T cell subsets involved in type 1 diabetes development in human. RECENT FINDINGS: T cells that infiltrate islets of people with type 1 diabetes (i) react towards known islet cell antigens but also unknown antigens, (ii) differ from one patient to another, and (iii) are also present in the circulation, but not in the islets, of healthy people...
August 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28663194/utilizing-and-interpreting-fdg-pet-ct-images-in-patients-referred-for-assessment-of-cardiac-sarcoidosis-the-devil-is-in-the-details
#10
Yang Lu, Darshan C Patel, Nadera Sweiss
No abstract text is available yet for this article.
June 29, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28661167/the-devil-s-in-the-detail-accessibility-of-specific-personal-memories-supports-rose-tinted-self-generalizations-in-mental-health-and-toxic-self-generalizations-in-clinical-depression
#11
Caitlin Hitchcock, Catrin Rees, Tim Dalgleish
Models of memory propose that separate systems underpin the storage and recollection of specific events from our past (e.g., the first day at school), and of the generic structure of our experiences (e.g., how lonely I am), and that interplay between these systems serves to optimize everyday cognition. Specifically, it is proposed that memories of discrete events help define the circumstances (boundary conditions) in which our generalized knowledge applies, thereby enhancing accuracy of memory-dependent cognitive processes...
June 29, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28657865/noninvasive-brain-stimulation-for-depression-the-devil-is-in-the-dosing
#12
COMMENT
Sarah H Lisanby
New England Journal of Medicine, Volume 376, Issue 26, Page 2593-2594, June 2017.
June 29, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28657164/monitoring-imperfect-detection-and-risk-optimization-of-a-tasmanian-devil-insurance-population
#13
Tracy M Rout, Chris Baker, Stewart Huxtable, Brendan A Wintle
Most species are imperfectly detected during biological surveys, creating uncertainty around their abundance or presence at a given location. Decision-makers managing threatened or pest species are regularly faced with this uncertainty, and there are a growing number of examples of managers dealing with imperfect detection. Wildlife diseases have the potential to drive species to extinction, and as such managing species with disease is an important part of conservation. Devil Facial Tumour Disease (DFTD) is one such disease that led to the listing of the Tasmanian devil (Sarcophilus harrisii) as endangered...
June 28, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28653625/between-the-devil-and-the-deep-blue-sea
#14
EDITORIAL
The Lancet Infectious Diseases
No abstract text is available yet for this article.
July 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28646816/the-devil-and-the-details
#15
EDITORIAL
Robert G Keim
No abstract text is available yet for this article.
March 2017: Journal of Clinical Orthodontics: JCO
https://www.readbyqxmd.com/read/28626387/the-case-for-abandoning-therapeutic-chelation-of-copper-ions-in-alzheimer-s-disease
#16
REVIEW
Simon C Drew
The "therapeutic chelation" approach to treating Alzheimer's disease (AD) evolved from the metals hypothesis, with the premise that small molecules can be designed to prevent transition metal-induced amyloid deposition and oxidative stress within the AD brain. Over more than 20 years, countless in vitro studies have been devoted to characterizing metal binding, its effect on Aβ aggregation, ROS production, and in vitro toxicity. Despite a lack of evidence for any clinical benefit, the conjecture that therapeutic chelation is an effective approach for treating AD remains widespread...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28620577/population-structure-of-the-soft-tick-ornithodoros-maritimus-and-its-associated-infectious-agents-within-a-colony-of-its-seabird-host-larus-michahellis
#17
Marlene Dupraz, Céline Toty, Elodie Devillers, Thomas Blanchon, Eric Elguero, Marion Vittecoq, Sara Moutailler, Karen D McCoy
The epidemiology of vector-borne zoonoses depends on the movement of both hosts and vectors, which can differ greatly in intensity across spatial scales. Because of their life history traits and small size, vector dispersal may be frequent, but limited in distance. However, little information is available on vector movement patterns at local spatial scales, and particularly for ticks, transmitting the greatest diversity of recognized infectious agents. To test the degree to which ticks can disperse and disseminate pathogens at local scales, we investigated the temporal dynamics and population structure of the soft tick Ornithodoros maritimus within a colony of its seabird host, the Yellow-legged gull Larus michahellis...
August 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28618299/is-the-devil-in-the-detail-a-randomised-controlled-trial-of-guided-internet-based-cbt-for-perfectionism
#18
Roz Shafran, Tracey D Wade, Sarah J Egan, Radha Kothari, Hannah Allcott-Watson, Per Carlbring, Alexander Rozental, Gerhard Andersson
An internet guided self-help cognitive-behavioural treatment (ICBT) for perfectionism was recently found to be effective (see this issue). Such studies stand in need of replication. The aim of this study was to report the outcomes and predictors of change when the treatment is delivered in a UK setting. A total of 120 people (Mean = 28.9 years; 79% female) were randomised to receive ICBT or wait-list control over 12 weeks (trial registration: NCT02756871). While there were strong similarities between the current study and its Swedish counterpart, there were also important differences in procedural details...
August 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28614869/a-rosa-canina-urtica-dioica-harpagophytum-procumbens-zeyheri-combination-significantly-reduces-gonarthritis-symptoms-in-a-randomized-placebo-controlled-double-blind-study
#19
Margret Moré, Joerg Gruenwald, Ute Pohl, Ralf Uebelhack
The special formulation MA212 (Rosaxan) is composed of rosehip (Rosa canina L.) puree/juice concentrate, nettle (Urtica dioica L.) leaf extract, and devil's claw (Harpagophytum procumbens DC. ex Meisn. or Harpagophytum zeyheri Decne.) root extract and also supplies vitamin D. It is a food for special medical purposes ([EU] No 609/2013) for the dietary management of pain in patients with gonarthritis.This 12-week randomized, placebo-controlled double-blind parallel-design study aimed to investigate the efficacy and safety of MA212 versus placebo in patients with gonarthritis...
June 14, 2017: Planta Medica
https://www.readbyqxmd.com/read/28604113/qsar-models-for-predicting-the-toxicity-of-piperidine-derivatives-against-aedes-aegypti
#20
J P Doucet, E Papa, A Doucet-Panaye, J Devillers
QSAR models are proposed for predicting the toxicity of 33 piperidine derivatives against Aedes aegypti. From 2D topological descriptors, calculated with the PaDEL software, ordinary least squares multilinear regression (OLS-MLR) treatment from the QSARINS software and machine learning and related approaches including linear and radial support vector machine (SVM), projection pursuit regression (PPR), radial basis function neural network (RBFNN), general regression neural network (GRNN) and k-nearest neighbours (k-NN), led to four-variable models...
June 12, 2017: SAR and QSAR in Environmental Research
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