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https://www.readbyqxmd.com/read/29099931/clinical-fractures-among-older-men-with-diabetes-are-mediated-by-diabetic-complications
#1
Richard H Lee, Richard Sloane, Carl Pieper, Kenneth W Lyles, Robert A Adler, Courtney Van Houtven, Joanne LaFleur, Cathleen Colón-Emeric
Introduction: Type 2 diabetes mellitus among older women has been associated with increased bone mineral density, but paradoxically increased fracture risk. Findings among older men have varied, and potential mechanisms have not been fully elucidated. Methods: Retrospective study of male Veterans 65-99 years of age who received primary care in the Veterans Health Administration (VHA) from 2000 to 2010, using administrative data from all 146 VHA medical centers linked to Centers for Medicare and Medicaid Services (CMS) Medicare fee-for-service data...
November 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28989893/an-intriguing-family-with-type-2-diabetes-mellitus-and-complete-heart-block
#2
Gaurav Agarwal, Satish Kumar Singh
Chronic hyperglycaemia of Type 2 Diabetes Mellitus (T2DM) causes long term damage to heart resulting in coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), and sudden death from arrhythmias. A 62 year old male presented to our emergency with complaint of sudden onset giddiness from last 2 hours. This was followed by loss of consciousness. Patient was a known case of T2DM since last 1 year. Family history- patient has two brothers who also have T2DM and both of them also developed Complete Heart Block (CHB) spontaneously...
September 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28989880/arrhythmias-in-type-2-diabetes-mellitus
#3
Gaurav Agarwal, Satish Kumar Singh
Chronic hyperglycaemia of Type 2 diabetes mellitus causes long term damage to heart resulting in coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), and sudden death from arrhythmias. AIMS: To study the prevalence of different types of arrhythmias in T2DM, particularly in association with Cardiac Autonomic Neuropathy (CAN). METHODS: A cross-sectional study including 100 patients of Type 2 Diabetes Mellitus (T2DM) presenting with cardiac arrhythmias, was done at our hospital over 2 years...
September 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28971322/the-diabetic-foot-as-a-proxy-for-cardiovascular-events-and-mortality-review
#4
REVIEW
Isa Dietrich, Gustavo Arruda Braga, Fernanda Gomes de Melo, Ana Carolina Calmon da Costa Silva Silva
PURPOSE OF REVIEW: This article reviewed very recent papers (2016) discussing or bringing clinical evidences of the possible common pathways leading to diabetic foot syndrome (DFS) and increased mortality rates. RECENT FINDINGS: Diabetic patients with diabetic foot syndrome have a mortality rate greater than twofold when compared with non-ulcerated diabetics. In addition, the 5-year mortality rate following amputation is estimated at 39-68%, a life expectancy comparable to aggressive types of cancer or advanced congestive heart failure...
October 2, 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28803840/development-and-validation-of-risk-equations-for-complications-of-type-2-diabetes-recode-using-individual-participant-data-from-randomised-trials
#5
Sanjay Basu, Jeremy B Sussman, Seth A Berkowitz, Rodney A Hayward, John S Yudkin
BACKGROUND: In view of substantial mis-estimation of risks of diabetes complications using existing equations, we sought to develop updated Risk Equations for Complications Of type 2 Diabetes (RECODe). METHODS: To develop and validate these risk equations, we used data from the Action to Control Cardiovascular Risk in Diabetes study (ACCORD, n=9635; 2001-09) and validated the equations for microvascular events using data from the Diabetes Prevention Program Outcomes Study (DPPOS, n=1018; 1996-2001), and for cardiovascular events using data from the Action for Health in Diabetes (Look AHEAD, n=4760; 2001-12)...
October 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28731281/glycaemia-control-and-the-risk-of-hospitalisation-for-infection-in-patients-with-type-2-diabetes-hong-kong-diabetes-registry
#6
Andrea O Y Luk, Eric S H Lau, Kitty K T Cheung, Alice P S Kong, Ronald C W Ma, Risa Ozaki, Francis C C Chow, Wing-Yee So, Juliana C N Chan
BACKGROUND: Infection occurs more commonly in diabetic patients compared with the general population and is an under-recognised but important morbidity in patients with diabetes. We examined the impact of glycaemic control on hospitalisation for infection in a large prospective cohort of Chinese adults with type 2 diabetes. METHODS: Between July 1994 and June 2014, 22 846 patients with type 2 diabetes underwent detailed assessment of metabolic control and diabetes complications...
July 21, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27583583/predictive-model-for-estimating-the-cost-of-incident-diabetes-complications
#7
Jia Zhu, Peter Kahn, Janine Knudsen, Sanjeev N Mehta, Robert A Gabbay
BACKGROUND: The cost of diabetes care accounts for a significant proportion of healthcare expenditures. Cost models based on updated incident complication rates and associated costs are needed to improve financial planning and quality assessment across the U.S. healthcare system. We developed a cost model using published data to estimate the direct medical costs of incident diabetes-related complications in a U.S. population of adults. MATERIALS AND METHODS: A systematic literature review of MEDLINE, EMBASE, and TRIP databases was conducted on studies reporting the incidence and/or cost of diabetes-related complications (cardiovascular disease, neuropathy, nephropathy, ophthalmological disease, and acute metabolic events)...
October 2016: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/26742231/-thiamine-the-road-experience-of-the-vitamin-as-a-manifestation-of-deficiency-in-a-world-of-abundance
#8
REVIEW
Einat Hershkowitz, Arie Markel
Thiamine or vitamin B1 is a water soluble vitamin of the vitamin B complex. It is synthetized by bacteria, fungi and plants and is an essential component of multicellular living organisms. Humans are not able to synthetize this vitamin and have to obtain it from different foods. Thiamin has a vital role in the normal function of the human body. It functions as a coenzyme in the catabolism of carbohydrates and amino acids and has an antioxidant role. It has an essential function in a series of metabolic processes related to energy production and conversion of sugar to ATP, as a catalyst in the Krebs cycle...
October 2015: Harefuah
https://www.readbyqxmd.com/read/25728036/cardiac-autonomic-neuropathy-the-hidden-cardiovascular-comorbidity-in-elderly-patients-with-chronic-obstructive-pulmonary-disease-attending-primary-care-settings
#9
Doha Rasheedy, Hend M Taha
AIM: To quantify the prevalence of chronic comorbidities including cardiac autonomic neuropathy among elderly patients with chronic obstructive pulmonary disease (COPD). METHODS: A cross-sectional study was carried out on 175 elderly male patients with COPD attending Ain Shams University Hospital, Cairo, Egypt. The comorbidities that might alter cardiac autonomic function in patients with COPD were identified. The patients without reported comorbidities underwent arterial blood gas analysis, pulmonary function tests and autonomic function assessment using cardiovascular reflexes...
March 2016: Geriatrics & Gerontology International
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