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https://www.readbyqxmd.com/read/28231421/varying-demographic-impacts-of-different-fisheries-on-three-mediterranean-seabird-species
#1
M Genovart, D Doak, J M Igual, S Sponza, J Kralj, D Oro
Fisheries have an enormous economic importance but reconciling their socio-economic features with the conservation and sustainability of marine ecosystems presents major challenges. Bycatch mortality from fisheries is clearly among the most serious global threats for marine ecosystems, affecting a wide range of top predators. Recent estimates report ca. 200,000 seabirds killed annually by bycatch in European waters. However there is an urgent need to rigorously estimate actual mortality rates and quantify effects of bycatch on populations...
February 23, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28231337/4d-dose-simulation-in-volumetric-arc-therapy-accuracy-and-affecting-parameters
#2
Thilo Sothmann, Tobias Gauer, René Werner
Radiotherapy of lung and liver lesions has changed from normofractioned 3D-CRT to stereotactic treatment in a single or few fractions, often employing volumetric arc therapy (VMAT)-based techniques. Potential unintended interference of respiratory target motion and dynamically changing beam parameters during VMAT dose delivery motivates establishing 4D quality assurance (4D QA) procedures to assess appropriateness of generated VMAT treatment plans when taking into account patient-specific motion characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28231329/changes-in-field-workability-and-drought-risk-from-projected-climate-change-drive-spatially-variable-risks-in-illinois-cropping-systems
#3
Bradley J Tomasek, Martin M Williams, Adam S Davis
As weather patterns become more volatile and extreme, risks introduced by weather variability will become more critical to agricultural production. The availability of days suitable for field work is driven by soil temperature and moisture, both of which may be altered by climate change. We projected changes in Illinois season length, spring field workability, and summer drought risk under three different emissions scenarios (B1, A1B, and A2) down to the crop district scale. Across all scenarios, thermal time units increased in parallel with a longer frost-free season...
2017: PloS One
https://www.readbyqxmd.com/read/28231328/integrating-the-sd-clue-s-and-invest-models-into-assessment-of-oasis-carbon-storage-in-northwestern-china
#4
Youjia Liang, Lijun Liu, Jiejun Huang
Spatio-temporal integrated assessment of land-use change impacts on carbon storage services is a new and important research field in land science and landscape ecology. The objective of this paper is to use an integrated SD-CLUE-S and InVEST model to simulate and predict land-use changes impacts during 2000-2018 on carbon storage at pixel and regional scales in the Zhangye oasis, Northwest China. The SD-CLUE-S model was used to simulate land-use change, and three land-use scenarios (current trend, moderate protection, and strict protection) were defined in collaboration with oasis socioeconomic development and ecological environment conservation by local government...
2017: PloS One
https://www.readbyqxmd.com/read/28231316/a-balanced-solution-to-the-cumulative-threat-of-industrialized-wind-farm-development-on-cinereous-vultures-aegypius-monachus-in-south-eastern-europe
#5
Dimitris P Vasilakis, D Philip Whitfield, Vassiliki Kati
Wind farm development can combat climate change but may also threaten bird populations' persistence through collision with wind turbine blades if such development is improperly planned strategically and cumulatively. Such improper planning may often occur. Numerous wind farms are planned in a region hosting the only cinereous vulture population in south-eastern Europe. We combined range use modelling and a Collision Risk Model (CRM) to predict the cumulative collision mortality for cinereous vulture under all operating and proposed wind farms...
2017: PloS One
https://www.readbyqxmd.com/read/28231278/interplay-between-fungicides-and-parasites-tebuconazole-but-not-copper-suppresses-infection-in-a-daphnia-metschnikowia-experimental-model
#6
Ana P Cuco, Nelson Abrantes, Fernando Gonçalves, Justyna Wolinska, Bruno B Castro
Natural populations are commonly exposed to complex stress scenarios, including anthropogenic contamination and their biological enemies (e.g., parasites). The study of the pollutant-parasite interplay is especially important, given the need for adequate regulations to promote improved ecosystem protection. In this study, a host-parasite model system (Daphnia spp. and the microparasitic yeast Metschnikowia bicuspidata) was used to explore the reciprocal effects of contamination by common agrochemical fungicides (copper sulphate and tebuconazole) and parasite challenge...
2017: PloS One
https://www.readbyqxmd.com/read/28231042/cost-effectiveness-analysis-of-four-simulated-colorectal-cancer-screening-interventions-north-carolina
#7
Kristen Hassmiller Lich, David A Cornejo, Maria E Mayorga, Michael Pignone, Florence K L Tangka, Lisa C Richardson, Tzy-Mey Kuo, Anne-Marie Meyer, Ingrid J Hall, Judith Lee Smith, Todd A Durham, Steven A Chall, Trisha M Crutchfield, Stephanie B Wheeler
INTRODUCTION: Colorectal cancer (CRC) screening rates are suboptimal, particularly among the uninsured and the under-insured and among rural and African American populations. Little guidance is available for state-level decision makers to use to prioritize investment in evidence-based interventions to improve their population's health. The objective of this study was to demonstrate use of a simulation model that incorporates synthetic census data and claims-based statistical models to project screening behavior in North Carolina...
February 23, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28230894/diagnosing-crime-and-diagnosing-disease-bias-reduction-strategies-in-the-forensic-and-clinical-sciences
#8
Joseph J Lockhart, Saty Satya-Murti
Cognitive effort is an essential part of both forensic and clinical decision-making. Errors occur in both fields because the cognitive process is complex and prone to bias. We performed a selective review of full-text English language literature on cognitive bias leading to diagnostic and forensic errors. Earlier work (1970-2000) concentrated on classifying and raising bias awareness. Recently (2000-2016), the emphasis has shifted toward strategies for "debiasing." While the forensic sciences have focused on the control of misleading contextual cues, clinical debiasing efforts have relied on checklists and hypothetical scenarios...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230650/acr-appropriateness-criteria%C3%A2-resectable-pancreatic-cancer
#9
William E Jones, W Waren Suh, May Abdel-Wahab, Ross A Abrams, Nilofer Azad, Prajnan Das, Jadranka Dragovic, Karyn A Goodman, Salma K Jabbour, Andre A Konski, Albert C Koong, Rachit Kumar, Percy Lee, Timothy M Pawlik, William Small, Joseph M Herman
Management of resectable pancreatic adenocarcinoma continues to present a challenge due to a paucity of high-quality randomized studies. Administration of adjuvant chemotherapy is widely accepted due to the high risk of systemic spread associated with pancreatic adenocarcinoma, but the role of radiation therapy is less clear. This paper reviews literature associated with resectable pancreatic cancer to include prognostic factors to aid in the selection of patients appropriate for adjuvant therapies. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
February 22, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28230639/mammalian-target-of-rapamycin-inhibition-clinical-transplantation-liver
#10
Björn Nashan
The evidence base concerning use of mammalian target of rapamycin (mTOR) inhibitor therapy after liver transplantation is evolving rapidly, clarifying their benefits and disadvantages in different clinical scenarios. The H2304 trial showed that starting everolimus at 1 month posttransplant, with reduced tacrolimus, achieves a sustained improvement in renal function versus standard tacrolimus-based therapy, with at least equivalent immunosuppressive efficacy. Randomized studies evaluating early discontinuation of CNI therapy after introduction of an mTOR inhibitor consistently demonstrated a substantial improvement in renal function versus standard CNI therapy...
February 23, 2017: Transplantation
https://www.readbyqxmd.com/read/28230257/a-general-framework-for-the-assessment-of-power-system-vulnerability-to-malicious-attacks
#11
R Piccinelli, G Sansavini, R Lucchetti, E Zio
The protection and safe operations of power systems heavily rely on the identification of the causes of damage and service disruption. This article presents a general framework for the assessment of power system vulnerability to malicious attacks. The concept of susceptibility to an attack is employed to quantitatively evaluate the degree of exposure of the system and its components to intentional offensive actions. A scenario with two agents having opposing objectives is proposed, i.e., a defender having multiple alternatives of protection strategies for system elements, and an attacker having multiple alternatives of attack strategies against different combinations of system elements...
February 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28230170/modeling-continuous-admixture-using-admixture-induced-linkage-disequilibrium
#12
Ying Zhou, Hongxiang Qiu, Shuhua Xu
Recent migrations and inter-ethnic mating of long isolated populations have resulted in genetically admixed populations. To understand the complex population admixture process, which is critical to both evolutionary and medical studies, here we used admixture induced linkage disequilibrium (LD) to infer continuous admixture events, which is common for most existing admixed populations. Unlike previous studies, we expanded the typical continuous admixture model to a more general scenario with isolation after a certain duration of continuous gene flow...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230161/robust-high-dimensional-bioinformatics-data-streams-mining-by-odr-iovfdt
#13
Dantong Wang, Simon Fong, Raymond K Wong, Sabah Mohammed, Jinan Fiaidhi, Kelvin K L Wong
Outlier detection in bioinformatics data streaming mining has received significant attention by research communities in recent years. The problems of how to distinguish noise from an exception and deciding whether to discard it or to devise an extra decision path for accommodating it are causing dilemma. In this paper, we propose a novel algorithm called ODR with incrementally Optimized Very Fast Decision Tree (ODR-ioVFDT) for taking care of outliers in the progress of continuous data learning. By using an adaptive interquartile-range based identification method, a tolerance threshold is set...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230056/threshold-of-long-term-survival-of-a-coastal-delphinid-in-anthropogenically-degraded-environment-indo-pacific-humpback-dolphins-in-pearl-river-delta
#14
Leszek Karczmarski, Shiang-Lin Huang, Stephen C Y Chan
Defining demographic and ecological threshold of population persistence can assist in informing conservation management. We undertook such analyses for the Indo-Pacific humpback dolphin (Sousa chinensis) in the Pearl River Delta (PRD) region, southeast China. We use adult survival estimates for assessments of population status and annual rate of change. Our estimates indicate that, given a stationary population structure and minimal risk scenario, ~2000 individuals (minimum viable population in carrying capacity, MVPk) can maintain the population persistence across 40 generations...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229974/molecular-mechanism-of-endosulfan-action-in-mammals
#15
Robin Sebastian, Sathees C Raghavan
Endosulfan is a broad-spectrum organochlorine pesticide, speculated to be detrimental to human health in areas of active exposure. However, the molecular insights to its mechanism of action remain poorly understood. In two recent studies, our group investigated the physiological and molecular aspects of endosulfan action using in vitro, ex vivo and in vivo analyses. The results showed that apart from reducing fertility levels in male animals, Endosulfan induced DNA damage that triggers compromised DNA damage response leading to undesirable processing of broken DNA ends...
March 2017: Journal of Biosciences
https://www.readbyqxmd.com/read/28229950/development-of-a-model-to-simulate-groundwater-inundation-induced-by-sea-level-rise-and-high-tides-in-honolulu-hawaii
#16
Shellie Habel, Charles H Fletcher, Kolja Rotzoll, Aly I El-Kadi
Many of the world's largest cities face risk of sea-level rise (SLR) induced flooding owing to their limited elevations and proximities to the coastline. Within this century, global mean sea level is expected to reach magnitudes that will exceed the ground elevation of some built infrastructure. The concurrent rise of coastal groundwater will produce additional sources of inundation resulting from narrowing and loss of the vertical unsaturated subsurface space. This has implications for the dense network of buried and low-lying infrastructure that exists across urban coastal zones...
February 20, 2017: Water Research
https://www.readbyqxmd.com/read/28229848/-the-extraction-non-extraction-dilemma-a-case-in-the-border
#17
José Chaqués-Asensi
INTRODUCTION: The extraction-non extraction dilemma is a classic one in the history of orthodontics [2, 19, 30]. In some cases the decision seems to be very clear whereas in some others discrepancies among clinicians can easily be found. Different authors propose different protocols in order to decide whether extractions are necessary in a particular clinical situation. In the last 25 years, the debate has been reframed with new non-extractionists trends based on new treatment philosophies or mechanics...
March 2017: L' Orthodontie Française
https://www.readbyqxmd.com/read/28229473/nurses-response-to-parents-speaking-up-efforts-to-ensure-their-hospitalized-child-s-safety-an-attribution-theory-perspective
#18
Sondos Basharat, Anat Drach-Zahavy
AIM: To understand how attribution processes (control and stability), which the nurse attributes to parental involvement in maintaining child safety, determine the nurse's response to a safety alert. BACKGROUND: Participation of parents in maintaining their child's safety is shown to reduce the incidence of and risk of clinical errors. Unless nurses respond appropriately to parents' safety alerts, this potential source of support could diminish. DESIGN: A 2 (controllability: high vs...
February 22, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28229404/derivation-of-mesenchymal-stem-cells-from-embryonic-stem-cells-a-non-variable-and-inexhaustive-source-of-adult-stem-cells
#19
Glen Lester Sequiera, Niketa Sareen, Ejlal Abu El-Rub, Sanjiv Dhingra
Mesenchymal stem cells (MSCs) provide an opportunity to bring the field of regenerative medicine to realization. A lot of clinical trials are presently trying to establish their applicability in real-world scenarios. Some of the biggest challenges encountered in bringing MSCs from bench to bedside are the number of MSCs required, their procurement from various sources, and the batch-to-batch variability. This often leads to inconclusive results within and between different studies. Therefore, we have hereby proposed a simple protocol to source mesenchymal stem cells through differentiation of embryonic stem cells...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28229070/improving-the-estimation-of-risk-adjusted-grouped-hospital-standardized-mortality-ratios-using-cross-jurisdictional-linked-administrative-data-a-retrospective-cohort-study
#20
Katrina Spilsbury, Diana Rosman, Janine Alan, Anna M Ferrante, James H Boyd, James B Semmens
BACKGROUND: Hospitals and death registries in Australia are operated under individual state government jurisdictions. Some state borders are located in heavily populated areas or are located near to major capital cities. Mortality indicators for hospital located near state borders may not be estimated accurately if patients are lost as they cross state borders. The aim of this study was to evaluate how cross-jurisdictional linkage of state hospital and death records across state borders may improve estimation of the hospital standardized mortality ratio (HSMR), a tool used in Australia as a hospital performance indicator...
2017: Frontiers in Public Health
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