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https://www.readbyqxmd.com/read/29055269/decision-making-measured-by-the-iowa-gambling-task-in-alcohol-use-disorder-and-gambling-disorder-a-systematic-review-and-meta-analysis
#1
REVIEW
Ildikó Kovács, Mara J Richman, Zoltán Janka, Aniko Maraz, Bálint Andó
BACKGROUND AND AIMS: Gambling disorder (GD) and alcohol use disorder (AD) have similar features, such as elevated impulsivity and decision-making deficits, which are directly linked to relapse and poor therapeutic outcomes. Our aim was to assess decision-making characteristics in GD and AD patients compared to healthy controls (HC) based on one of the most frequently used measures of decision-making: the Iowa Gambling Task (IGT). METHODS: In our systematic literature search of three databases, we identified 1198 empirical articles that mentioned decision-making deficits with the use of the IGT in patients diagnosed with either AD or GD...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055224/primary-suction-thrombectomy-for-acute-ischemic-stroke-a-meta-analysis-of-the-current-literature
#2
Jin Pyeong Jeon, Sung-Eun Kim, Chul Ho Kim
OBJECTIVES: We conducted a meta-analysis to assess the angiographic and clinical outcomes for ischemic stroke patients treated with primary suction thrombectomy and to compare the procedural outcomes based on the treatment strategies (primary suction vs. stent retriever thrombectomy). PATIENTS AND METHODS: We conducted a systemic literature review through an online data base from January 2004 through December 2016. The primary outcomes were rate of successful recanalization on final angiogram and good outcome three months after stroke onset...
October 3, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29055223/pituitary-apoplexy-a-single-center-retrospective-study-from-the-neurosurgical-perspective-and-review-of-the-literature
#3
Agnieszka Grzywotz, Bernadette Kleist, Lars C Möller, Volkmar H Hans, Sophia Göricke, Ulrich Sure, Oliver Müller, Ilonka Kreitschmann-Andermahr
OBJECTIVE: Thunderclap headache and visual disturbances are typical clinical features of pituitary apoplexy (PA). Because of the acute symptomatology, many patients are referred to a neurosurgical department without prior endocrinological assessment. It is the aim of the present study to analyze initial presenting symptoms, outcome and associated endocrine disturbances in a cohort of patients with pituitary apoplexy primarily seen by neurosurgeons. PATIENTS AND METHODS: Retrospective single-center study in a neurosurgical department...
October 10, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29055216/thoracic-manual-therapy-is-not-more-effective-than-placebo-thoracic-manual-therapy-in-patients-with-shoulder-dysfunctions-a-systematic-review-with-meta-analysis
#4
REVIEW
Paolo Bizzarri, Luca Buzzatti, Erik Cattrysse, Aldo Scafoglieri
BACKGROUND: Manual treatments targeting different regions (shoulder, cervical spine, thoracic spine, ribs) have been studied to deal with patients complaining of shoulder pain. Thoracic manual treatments seem able to produce beneficial effects on this group of patients. However, it is not clear whether the patient improvement is a consequence of thoracic manual therapy or a placebo effect. OBJECTIVES: To compare the efficacy of thoracic manual therapy and placebo thoracic manual treatment for patients with shoulder dysfunction...
October 14, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29055207/hormonal-contraceptive-use-in-smokers-prevalence-of-use-and-associations-with-smoking-motives
#5
Alicia M Allen, Kim Lundeen, Lynn E Eberly, Sharon S Allen, Mustafa al'Absi, Myra Muramoto, Dorothy Hatsukami
INTRODUCTION: While endogenous sex hormones influence smoking-related outcomes, little is known about the role of hormonal contraceptives (HCs). This is despite dated estimates suggesting that HC use is prevalent among female smokers. Therefore, we sought to update estimates of the prevalence of HC use among female smokers and explore the association of HC use with various smoking motives (SMs). METHODS: This online cross-sectional survey recruited female smokers between the ages of 18-35...
October 13, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055130/randomized-trial-of-combined-cabergoline-and-coasting-in-preventing-ovarian-hyperstimulation-syndrome-during-in-vitro-fertilization-intracytoplasmic-sperm-injection-cycles
#6
Yasmin A Bassiouny, Dina M R Dakhly, Yomna A Bayoumi, Noha M Salaheldin, Hisham M Gouda, Ayman A Hassan
OBJECTIVE: To assess the efficacy of coasting alone, cabergoline alone, or combining both interventions for preventing ovarian hyperstimulation syndrome (OHSS) among high-risk patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment cycles. METHODS: The present randomized controlled trial was conducted at the IVF unit of a university hospital in Cairo between October 28, 2013, and July 31, 2015. Patients undergoing IVF/ICSI considered at risk of OHSS were randomly allocated to coasting, cabergoline, or combined coasting and cabergoline...
October 21, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29055072/reproductive-outcome-of-women-with-congenital-uterine-anomalies-after-assisted-reproduction-a-prospective-observational-study
#7
Matthew Prior, Alison Richardson, Sonia Asif, Lukasz Polanski, Michelle Parris-Larkin, Jane Chandler, Lynne Fogg, Pooja Jassal, Jim G Thornton, Nick J Raine-Fenning
OBJECTIVE: To assess the effect on reproductive outcome of congenital uterine anomalies in subfertile women in women undergoing assisted reproduction. METHODS: All women referred with subfertility between May 2009 and November 2015 who underwent assisted reproduction. As part of their initial assessment each woman was assessed by pelvic three-dimensional ultrasonography. The uterine morphology was classified using the modified American Fertility Society (AFS) classification of congenital anomalies...
October 21, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29055064/clinical-relevance-of-peroxisome-proliferator-activated-receptor-%C3%AE-gene-polymorphisms-with-sepsis
#8
Yu Liu, Wenhui Wan, Fang Fang, Lei Guo, Yusheng Zhao, Xinghu Zhang, Fang Huang
BACKGROUND: Peroxisome proliferator-activated receptor-γ (PPARγ) is a regulator of inflammation. This study aimed to explore associations between PPARγ gene single-nucleotide polymorphisms (SNPs) and susceptibility to and clinical outcome of sepsis in the North China Han population. METHODS: This study included 303 patients with sepsis and 303 controls. We conducted genetic typing for 13 common PPARγ gene SNPs (improved multiplex ligation detection reaction), linkage disequilibrium mapping, and haplotype inference...
October 21, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29055052/pregnancy-prior-to-recurrent-pregnancy-loss-more-often-complicated-by-post-term-birth-and-perinatal-death
#9
Marise M Wagner, Jantien Visser, Harjo Verburg, Chantal W P M Hukkelhoven, Jan M M van Lith, Kitty W M Bloemenkamp
INTRODUCTION: The cause of recurrent pregnancy loss remains often unknown. Possibly, pathophysiological pathways are shared with other pregnancy complications. MATERIAL AND METHODS: All women with secondary recurrent pregnancy loss (SRPL) visiting Leiden University Medical Centre (January 2000-2015) were included in this retrospective cohort to assess whether women with SRPL have a more complicated first pregnancy compared to control women. SRPL was defined as ≥ 3 consecutive pregnancy losses before 22 weeks' gestation, with a previous birth...
October 21, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29054911/ixazomib-significantly-prolongs-progression-free-survival-in-high-risk-relapsed-refractory-myeloma-patients
#10
Hervé Avet-Loiseau, Nizar J Bahlis, Wee-Joo Chng, Tamas Masszi, Luisa Viterbo, Ludek Pour, Peter Ganly, Antonio Palumbo, Michele Cavo, Christian Langer, Andrzej Pluta, Arnon Nagler, Shaji Kumar, Dina Ben-Yehuda, S Vincent Rajkumar, Jesus San-Miguel, Deborah Berg, Jianchang Lin, Helgi van de Velde, Dixie-Lee Esseltine, Alessandra di Bacco, Philippe Moreau, Paul G Richardson
Certain cytogenetic abnormalities are known to adversely impact outcomes in patients with multiple myeloma (MM). The phase 3 TOURMALINE-MM1 study demonstrated a significant improvement in progression-free survival (PFS) with ixazomib-lenalidomide-dexamethasone (IRd) compared with placebo-Rd. This pre-planned analysis assessed the efficacy and safety of IRd versus placebo-Rd according to cytogenetic risk, as assessed using fluorescence in-situ hybridization. High-risk cytogenetic abnormalities were defined as del(17p), t(4;14), and/or t(14;16); additionally, patients were assessed for 1q21 amplification...
October 20, 2017: Blood
https://www.readbyqxmd.com/read/29054834/evaluation-of-web-based-continuing-professional-development-courses-aggregate-mixed-methods-model
#11
Arezoo Ebn Ahmady, Megan Barker, Myra Fahim, Rosa Dragonetti, Peter Selby
BACKGROUND: Many continuing professional development (CPD) Web-based programs are not explicit about underlying theory and fail to demonstrate impact. OBJECTIVE: The aim of this study was to develop and apply an aggregate mixed-methods evaluation model to describe the paradigm, theoretical framework, and methodological approaches used to evaluate a CPD course in tobacco dependence treatment, the Training Enhancement in Applied Cessation Counseling and Health (TEACH) project...
October 20, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/29054833/pregnant-women-s-perceptions-of-the-risks-and-benefits-of-disclosure-during-web-based-mental-health-e-screening-versus-paper-based-screening-randomized-controlled-trial
#12
Dawn Kingston, Anne Biringer, Sander Veldhuyzen van Zanten, Rebecca Giallo, Sarah McDonald, Glenda MacQueen, Lydia Vermeyden, Marie-Paule Austin
BACKGROUND: Pregnant women's perceptions of the risks and benefits during mental health screening impact their willingness to disclose concerns. Early research in violence screening suggests that such perceptions may vary by mode of screening, whereby women view the anonymity of e-screening as less risky than other approaches. Understanding whether mode of screening influences perceptions of risk and benefit of disclosure is important in screening implementation. OBJECTIVE: The objective of this randomized controlled trial was to compare the perceptions of pregnant women randomized to a Web-based screening intervention group and a paper-based screening control group on the level of risk and benefit they perceive in disclosing mental health concerns to their prenatal care provider...
October 20, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29054815/whole-brain-radiotherapy-or-autologous-stem-cell-transplantation-as-consolidation-strategies-after-high-dose-methotrexate-based-chemoimmunotherapy-in-patients-with-primary-cns-lymphoma-results-of-the-second-randomisation-of-the-international-extranodal-lymphoma
#13
Andrés J M Ferreri, Kate Cwynarski, Elisa Pulczynski, Christopher P Fox, Elisabeth Schorb, Paul La Rosée, Mascha Binder, Alberto Fabbri, Valter Torri, Eleonora Minacapelli, Monica Falautano, Fiorella Ilariucci, Achille Ambrosetti, Alexander Roth, Claire Hemmaway, Peter Johnson, Kim M Linton, Tobias Pukrop, Jette Sønderskov Gørløv, Monica Balzarotti, Georg Hess, Ulrich Keller, Stephan Stilgenbauer, Jens Panse, Alessandra Tucci, Lorella Orsucci, Francesco Pisani, Alessandro Levis, Stefan W Krause, Hans J Schmoll, Bernd Hertenstein, Mathias Rummel, Jeffery Smith, Michael Pfreundschuh, Giuseppina Cabras, Francesco Angrilli, Maurilio Ponzoni, Martina Deckert, Letterio S Politi, Jürgen Finke, Michele Reni, Franco Cavalli, Emanuele Zucca, Gerald Illerhaus
BACKGROUND: The International Extranodal Lymphoma Study Group-32 (IELSG32) trial is an international randomised phase 2 study that addresses two key clinical questions in the treatment of patients with newly diagnosed primary CNS lymphoma. Results of the first randomisation have demonstrated that methotrexate, cytarabine, thiotepa, and rituximab (called the MATRix regimen) is the induction combination associated with significantly better outcome compared with the other induction combinations tested...
October 17, 2017: Lancet Haematology
https://www.readbyqxmd.com/read/29054803/comparison-of-short-term-effects-of-mobilization-with-movement-and-kinesiotaping-on-pain-function-and-balance-in-patellofemoral-pain
#14
Serdar Demirci, Gizem Irem Kinikli, Michael J Callaghan, Volga Bayrakci Tunay
OBJECTIVE: The aim of this study was to compare the short-term effects of Mobilization with movement (MWM) and Kinesiotaping (KT) on patients with patellofemoral pain (PFP) respect to pain, function and balance. METHODS: Thirty-five female patients diagnosed with unilateral PFP were assigned into 2 groups. The first group (n = 18) received two techniques of MWM intervention (Straight Leg-Raise with Traction and Tibial Gliding) while KT was applied to the other group (n = 17)...
October 17, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29054782/multi-level-spondylolysis-repair-using-the-smiley-face-technique-with-3d-intraoperative-spinal-navigation
#15
Mathew R Voisin, Christopher D Witiw, Ryan Deorajh, Daipayan Guha, Adetunji Oremakinde, Shelly Wang, Victor Yang
BACKGROUND / OBJECTIVE: Multi-level spondylolysis is a rare cause of progressive lower back pain and patients that fail conservative management are treated surgically. Direct repair methods can maintain mobility and lead to decreased morbidity compared with spinal fusion in single-level spondylolysis. In this paper, we present a patient with non-adjacent multi-level spondylolysis that underwent the 'smiley face' technique of direct multi-level repair without fusion using 3D intraoperative spinal navigation...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29054774/prognostic-significance-of-ultraearly-hematoma-growth-in-spontaneous-intracerebral-hemorrhage-patients-receiving-hematoma-evacuation
#16
Zhiyuan Yu, Jun Zheng, Rui Guo, Lu Ma, Mou Li, Xiaoze Wang, Sen Lin, Chao You, Hao Li
OBJECTIVE: To investigate the association between ultraearly hematoma growth (uHG) and clinical outcome in patients with spontaneous intracerebral hemorrhage (sICH) receiving hematoma evacuation. METHODS: Supratentorial sICH patients receiving hematoma evacuation within 24 hours after ictus were enrolled in this study. uHG was defined as baseline hematoma volume/onset-to-computed tomography (CT) time (ml/h). The outcome was assessed using modified Rankin Scale (mRS) score at 3 months...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29054735/associations-between-neural-reward-processing-and-binge-eating-among-adolescent-girls
#17
Lindsay P Bodell, Jennifer E Wildes, Andrea B Goldschmidt, Rachel Lepage, Kate E Keenan, Amanda E Guyer, Alison E Hipwell, Stephanie D Stepp, Erika E Forbes
PURPOSE: Neuroimaging studies suggest that altered brain responses to food-related cues in reward-sensitive regions characterize individuals who experience binge-eating episodes. However, the absence of longitudinal data limits the understanding of whether reward-system alterations increase vulnerability to binge eating, as theorized in models of the development of this behavior. METHODS: Adolescent girls (N = 122) completed a functional magnetic resonance imaging monetary reward task at age 16 years as part of an ongoing longitudinal study...
October 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29054718/determination-of-the-impact-of-melanoma-surgical-timing-on-survival-using-the-national-cancer-database
#18
Ruzica Z Conic, Claudia I Cabrera, Alok A Khorana, Brian R Gastman
BACKGROUND: The ideal timing for melanoma treatment, predominantly surgery, remains undetermined. Patient concern for receiving immediate treatment often exceeds surgeon or hospital availability, requiring establishment of a safe window for melanoma surgery. OBJECTIVE: To assess the impact of time to definitive melanoma surgery on overall survival. METHODS: Patients with stage I to III cutaneous melanoma and with available time to definitive surgery and overall survival were identified by using the National Cancer Database (N = 153,218)...
September 27, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29054662/assessing-the-ecological-effects-of-water-stress-and-pollution-in-a-temporary-river-implications-for-water-management
#19
Ioannis Karaouzas, Evangelia Smeti, Aikaterini Vourka, Leonidas Vardakas, Aggeliki Mentzafou, Elisabet Tornés, Sergi Sabater, Isabel Muñoz, Nikolaos Th Skoulikidis, Eleni Kalogianni
Temporary rivers are dynamic and complex ecosystems that are widespread in arid and semi-arid regions, such as the Mediterranean. Biotic communities adapted in their intermittent nature could withstand recurrent drought events. However, anthropogenic disturbances in the form of water stress and chemical pollution challenge biota with unpredictable outcomes, especially in view of climate change. In this study we assess the response of the biotic community of a temporary river to environmental stressors, focusing on water stress and pollution...
October 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29054589/baseline-asthma-burden-comorbidities-and-biomarkers-in-omalizumab-treated-patients-in-prospero
#20
Bradley E Chipps, Robert S Zeiger, Allan T Luskin, William W Busse, Benjamin L Trzaskoma, Evgeniya N Antonova, Hooman Pazwash, Susan L Limb, Paul G Solari, Noelle M Griffin, Thomas B Casale
BACKGROUND: Patients included in clinical trials do not necessarily reflect the real-world population. OBJECTIVE: To understand the characteristics, including disease and comorbidity burden, of patients with asthma receiving omalizumab in a real-world setting. METHODS: The Prospective Observational Study to Evaluate Predictors of Clinical Effectiveness in Response to Omalizumab (PROSPERO) was a US-based, multicenter, single-arm, and prospective study...
October 17, 2017: Annals of Allergy, Asthma & Immunology
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