keyword
https://read.qxmd.com/read/38491405/test-retest-reliability-and-concurrent-validity-assessment-of-a-novel-high-frequency-sensor-device-for-anterior-tibial-translation-measurement-in-loaded-and-unloaded-condition-an-exploratory-cross-sectional-study
#21
JOURNAL ARTICLE
Valentin Deiss, Philippe Bähler, Pascal Kolly, Anton Schärer, Philippe Henle, Patric Eichelberger, Nathanael Lutz, Heiner Baur
BACKGROUND: Magnetic resonance imaging (MRI) and manual tests remain the standard for diagnosing anterior cruciate ligament (ACL) rupture. Furthermore, the passive knee displacement, also described as anterior tibial translation (ATT), is used in order to make decisions about surgery or to assess rehabilitation outcomes. Unfortunately, these manual tests are limited to passive situations, and their application to assess knee stability in loaded, weight-bearing positions are missing. Therefore, a new device with high-performance sensors and a new sensor setting was developed...
March 16, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38490890/biomimetic-hepatic-lobules-from-three-dimensional-imprinted-cell-sheets
#22
JOURNAL ARTICLE
Jinglin Wang, Danqing Huang, Hanxu Chen, Yuanjin Zhao
Liver-tissue engineering has proven valuable in treating liver diseases, but the construction of liver tissues with high fidelity remains challenging. Here, we present a novel three-dimensional (3D)-imprinted cell-sheet strategy for the synchronous construction of biomimetic hepatic microtissues with high accuracy in terms of cell type, density, and distribution. To achieve this, the specific composition of hepatic cells in a normal human liver was determined using a spatial proteogenomics dataset. The data and biomimetic hepatic micro-tissues with hexagonal hollow cross-sections indicate that cell information was successfully generated using a homemade 3D-imprinted device for layer-by-layer imprinting and assembling the hepatic cell sheets...
February 28, 2024: Science Bulletin
https://read.qxmd.com/read/38490481/systemically-administered-zoledronic-acid-activates-locally-implanted-synthetic-hydroxyapatite-particles-enhancing-peri-implant-bone-formation-a-regenerative-medicine-approach-to-improve-fracture-fixation
#23
JOURNAL ARTICLE
Vetra Markeviciute, Manoj Puthia, Linnea Arvidsson, Yang Liu, Elin Törnquist, Alessandro Tengattini, Jintian Huang, Yiguang Bai, Corina Vater, Robertas Petrolis, Stefan Zwingenberger, Algimantas Krisciukaitis, Alfredas Smailys, Saulius Lukosevicius, Mindaugas Stravinskas, Hanna Isaksson, Sarunas Tarasevicius, Lars Lidgren, Magnus Tägil, Deepak Bushan Raina
Fracture fixation in an ageing population is challenging and fixation failure increases mortality and societal costs. We report a novel fracture fixation treatment by applying a hydroxyapatite (HA) based biomaterial at the bone-implant interface and biologically activating the biomaterial by systemic administration of a bisphosphonate (zoledronic acid, ZA). We first used an animal model of implant integration and applied a calcium sulphate (CaS)/HA biomaterial around a metallic screw in the tibia of osteoporotic rats...
March 13, 2024: Acta Biomaterialia
https://read.qxmd.com/read/38490146/metal-organic-framework-based-ratiometric-point-of-care-testing-for-quantitative-visual-detection-of-nitrite
#24
JOURNAL ARTICLE
Maosheng Liang, Yifan Gao, Xiaoling Sun, Rong-Mei Kong, Lian Xia, Fengli Qu
Nitrite (NO2 - ) is categorized as a carcinogenic substance and is subjected to severe limitations in water and food. To safeguard the public's health, developing fast and convenient methods for determination of NO2 - is of significance. Point-of-care testing (POCT) affords demotic measurement of NO2 - and shows huge potential in future technology beyond those possible with traditional methods. Here, a novel ratiometric fluorescent nanoprobe (Ru@MOF-NH2 ) is developed by integrating UiO-66-NH2 with tris(2,2'-bipyridyl)ruthenium(II) ([Ru(bpy)3 ]2+ ) through a one-pot approach...
March 12, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38490025/advancing-amyotrophic-lateral-sclerosis-disease-diagnosis-a-lab-on-chip-electrochemical-immunosensor-for-ultra-sensitive-tdp-43-protein-detection-and-monitoring-in-serum-patients
#25
JOURNAL ARTICLE
Antonio Turco, Elisabetta Primiceri, Maria Serena Chiriacò, Velia La Pesa, Francesco Ferrara, Nilo Riva, Angelo Quattrini, Alessandro Romano, Giuseppe Maruccio
The global increase in population aging has led to a rise in neurodegenerative diseases (NDs), posing significant challenges to public health. Developing selective and specific biomarkers for early diagnosis and drug development is crucial addressing the growing burden of NDs. In this context, the RNA-binding protein TDP-43 has emerged as a promising biomarker for amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), and TDP-43-associated proteinopathies. However, existing detection methods suffer from limitations such as cost, complexity, and operator dependence...
March 6, 2024: Talanta
https://read.qxmd.com/read/38490022/an-intelligent-wearable-artificial-pancreas-patch-based-on-a-microtube-glucose-sensor-and-an-ultrasonic-insulin-pump
#26
JOURNAL ARTICLE
Xiaojin Luo, Jiaye Xie, Li Yang, Yue Cui
In order to improve the living standards of diabetes patients and reduce the negative health effects of this disease, the medical community has been actively searching for more effective treatments. In recent years, an artificial pancreas has emerged as an important approach to managing diabetes. Despite these recent advances, meeting the requirements for miniaturized size, accurate sensing and large-volume pumping capability remains a great challenge. Here, we present a novel miniaturized artificial pancreas based on a long microtube sensor integrated with an ultrasonic pump...
March 14, 2024: Talanta
https://read.qxmd.com/read/38489751/gradient-graphene-spiral-sponges-for-efficient-solar-evaporation-and-zero-liquid-discharge-desalination-with-directional-salt-crystallization
#27
JOURNAL ARTICLE
Demin Zhao, Meichun Ding, Tianhao Lin, Zhenying Duan, Rui Wei, Panpan Feng, Jiahui Yu, Chen-Yang Liu, Chenwei Li
Solar desalination is a promising strategy to utilize solar energy to purify saline water. However, the accumulation of salt on the solar evaporator surface severely reduces light absorption and evaporation performance. Herein, a simple and eco-friendly method to fabricate a 3D gradient graphene spiral sponge (GGS sponge) is presented that enables high-rate solar evaporation and zero liquid discharge (ZLD) desalination of high-salinity brine. The spiral structure of the GGS sponge enhances energy recovery, while the gradient network structures facilitate radial brine transport and directional salt crystallization, which cooperate to endow the sponge with superior solar evaporation (6...
March 15, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38489469/virtual-reality-images-created-on-the-back-and-front-of-a-display
#28
JOURNAL ARTICLE
Yoichi Ogata, Mykyta Kolchiba
To better investigate the biological mechanism of microorganisms, we developed a novel, to the best of our knowledge, virtual reality (VR) microscope that incorporates a head-mounted display (HMD) that creates VR images with a digital microscope. This type of VR microscope can be used with any type of optical microscope. The fabricated microscope is quite different from a common bifocal device because it can create VR images on the back and front of a display. If the VR images are displayed with object (OBJ) images, they are observable in [2 × 2] (back and front VR images and OBJ images; 2 × 2 = 4 images)...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38489439/hyperspectral-digital-holography-realized-by-using-an-electro-optical-frequency-comb-via-injection-locking
#29
JOURNAL ARTICLE
Ziwen Long, ZhengChao Yuan, Xinyu Fan, Zuyuan He
Hyperspectral digital holography (HSDH) is a versatile holographic imaging technique that offers large unambiguous depth range and spectroscopic information. In this Letter, we propose a novel, to the best of our knowledge, HSDH system that is realized by using an electro-optical frequency comb (EOFC) via injection locking. In comparison with conventional dual-comb HSDH, the proposed system only requires one EOFC and few other devices, which not only simplifies the system structure and reduces the cost but also improves the imaging speed...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38489426/loading-effect-based-three-dimensional-microfabrication-empowers-on-chip-brillouin-optomechanics
#30
JOURNAL ARTICLE
Peng Lei, Mingyu Xu, Yunhui Bai, Zhangyuan Chen, Xiaopeng Xie
The acousto-optic interaction known as stimulated Brillouin scattering (SBS) has emerged as a fundamental principle for realizing crucial components and functionalities in integrated photonics. However, the main challenge of integrating Brillouin devices is how to effectively confine both optical and acoustic waves. Apart from that, the manufacturing processes for these devices need to be compatible with standard fabrication platforms and streamlined to facilitate their large-scale integration. Here, we demonstrate a novel, to the best of our knowledge, suspended nanowire structure that can tightly confine photons and phonons...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38489103/rendezvous-pierce-technique-establishing-a-channel-through-severe-calcification-in-infrainguinal-arterial-lesions-using-needle-rendezvous
#31
JOURNAL ARTICLE
Takuya Haraguchi, Masanaga Tsujimoto, Yoshifumi Kashima, Katsuhiko Sato, Tsutomu Fujita
BACKGROUND: Severe calcification often prevents device passage and balloon expansion in cases of lower extremity artery disease. To address this limitation, we introduced a novel calcium modification technique called Rendezvous-PIERCE (R-PIERCE). METHODS: A needle was inserted in a retrograde manner and advanced to touch the tip of an antegrade guidewire within the lesion. Then, the guidewire was advanced into the lumen of the needle to achieve partial guidewire externalization, also known as needle rendezvous...
March 15, 2024: CVIR Endovascular
https://read.qxmd.com/read/38488747/self-competitive-growth-of-cspbbr-3-planar-nanowire-array
#32
JOURNAL ARTICLE
Chao Fan, Meiyi Zhu, Xing Xu, Peng Wang, Qinglin Zhang, Xingliang Dai, Ke Yang, Haiping He, Zhizhen Ye
Semiconductor planar nanowire arrays (PNAs) are essential for achieving large-scale device integration. Direct heteroepitaxy of PNAs on a flat substrate is constrained by the mismatch in crystalline symmetry and lattice parameters between the substrate and epitaxial nanowires. This study presents a novel approach termed "self-competitive growth" for heteroepitaxy of CsPbBr3 PNAs on mica. The key to inducing the self-competitive growth of CsPbBr3 PNAs on mica involves restricting the nucleation of CsPbBr3 nanowires in a high-adsorption region, which is accomplished by overlaying graphite sheets on the mica surface...
March 15, 2024: Nano Letters
https://read.qxmd.com/read/38488489/lipidomic-changes-in-a-novel-sepsis-outcome-based-analysis-reveals-potent-pro-inflammatory-and-pro-resolving-signaling-lipids
#33
JOURNAL ARTICLE
Dawoud Sulaiman, Dongyuan Wu, Lauren Page Black, Kevin J Williams, Kiley Graim, Susmita Datta, Srinivasa T Reddy, Faheem W Guirgis
The purpose of this study was to investigate changes in the lipidome of patients with sepsis to identify signaling lipids associated with poor outcomes that could be linked to future therapies. Adult patients with sepsis were enrolled within 24h of sepsis recognition. Patients meeting Sepsis-3 criteria were enrolled from the emergency department or intensive care unit and blood samples were obtained. Clinical data were collected and outcomes of rapid recovery, chronic critical illness (CCI), or early death were adjudicated by clinicians...
March 2024: Clinical and Translational Science
https://read.qxmd.com/read/38488282/strong-linearly-polarized-light-emission-by-coupling-out-of-plane-exciton-to-anisotropic-gap-plasmon-nanocavity
#34
JOURNAL ARTICLE
Kai Xu, Zhen Zou, Wenfei Li, Lan Zhang, Maowen Ge, Tao Wang, Wei Du
With exceptional quantum confinement, 2D monolayer semiconductors support a strong excitonic effect, making them an ideal platform for exploring light-matter interactions and as building blocks for novel optoelectronic devices. Different from the well-known in-plane excitons in transition metal dichalcogenides (TMD), the out-of-plane excitons in indium selenide (InSe) usually show weak emission, which limits their applications as light sources. Here, by embedding InSe in an anisotropic gap plasmon nanocavity, we have realized plasmon-enhanced linearly polarized photoluminescence with an anisotropic ratio up to ∼140, corresponding to degree of polarization (DoP) of ∼98...
March 15, 2024: Nano Letters
https://read.qxmd.com/read/38487978/investigation-of-the-lattice-thermal-transport-properties-of-janus-xclo-x-cr-ir-monolayers-by-first-principles-calculations
#35
JOURNAL ARTICLE
Peng Gao, Xihao Chen, Zonghang Liu, Jiwen Li, Ning Wang
In the context of the global energy crisis, the development of high-performance heat transport devices within nano scales has become increasingly important. Theoretical discovery and evaluation of novel structures with high performance in thermal conductivity by affordable calculations could provide significant instructions for experimental studies focusing on thermoelectric device development. For 2-dimensional (2D) functional materials, their heat transport efficiency is correlated with their electronic properties and structural features...
March 15, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38486923/exploring-eeg-based-motor-imagery-decoding-a-dual-approach-using-spatial-features-and-spectro-spatial-deep-learning-model-ifnet
#36
JOURNAL ARTICLE
Javier V Juan, Rubén Martínez, Eduardo Iáñez, Mario Ortiz, Jesús Tornero, José M Azorín
INTRODUCTION: In recent years, the decoding of motor imagery (MI) from electroencephalography (EEG) signals has become a focus of research for brain-machine interfaces (BMIs) and neurorehabilitation. However, EEG signals present challenges due to their non-stationarity and the substantial presence of noise commonly found in recordings, making it difficult to design highly effective decoding algorithms. These algorithms are vital for controlling devices in neurorehabilitation tasks, as they activate the patient's motor cortex and contribute to their recovery...
2024: Frontiers in Neuroinformatics
https://read.qxmd.com/read/38486302/correction-challenges-and-solutions-to-recruitment-of-neonates-and-children-having-cardiac-surgery-into-a-study-using-a-novel-sampling-device
#37
Terrie Walker-Smith, Daniel Fudulu, Aravind Ramesh, Karen Sheehan, Julie Madden, Lucy Culliford, Jonathan Evans, Gianni D Angelini, Thomas Upton, Ben Gibbison
No abstract text is available yet for this article.
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38485984/proposing-todd-graphene-as-a-novel-porous-2d-carbon-allotrope-designed-for-superior-lithium-ion-battery-efficiency
#38
JOURNAL ARTICLE
E A J Santos, K A L Lima, L A Ribeiro Junior
The category of 2D carbon allotropes has gained considerable interest due to its outstanding optoelectronic and mechanical characteristics, which are crucial for various device applications, including energy storage. This study uses density functional theory calculations, ab initio molecular dynamics (AIMD), and classical reactive molecular dynamics (MD) simulations to introduce TODD-Graphene, an innovative 2D planar carbon allotrope with a distinctive porous arrangement comprising 3-8-10-12 carbon rings. TODD-G exhibits intrinsic metallic properties with a low formation energy and stability in thermal and mechanical behavior...
March 14, 2024: Scientific Reports
https://read.qxmd.com/read/38485796/comparison-of-comfort-and-tear-stability-with-two-novel-silicone-hydrogel-daily-disposable-contact-lenses
#39
JOURNAL ARTICLE
Tatsuya Mimura, Hidetaka Noma, Masao Yamaguchi, Koichiro Shinbo
BACKGROUND: The surface wettability of soft contact lenses (SCLs) affects the wearing comfort. Verofilcon A is a daily disposable silicone hydrogel contact lens with SMARTSURFACE® technology, ensuring high surface wettability. PURPOSE: To evaluate tear stability on the surface of verofilcon A and narafilcon A SCLs and correlate these findings with clinical parameters and patients' discomfort. METHODS: Sixty-two SCL wearers (124 eyes) with SCL discomfort were randomly assigned to use narafilcon A (control SCL) and verofilcon A for 2 weeks each by crossover...
March 14, 2024: International Ophthalmology
https://read.qxmd.com/read/38485764/an-optrode-array-for-spatiotemporally-precise-large-scale-optogenetic-stimulation-of-deep-cortical-layers-in-non-human-primates
#40
JOURNAL ARTICLE
Andrew M Clark, Alexander Ingold, Christopher F Reiche, Donald Cundy, Justin L Balsor, Frederick Federer, Niall McAlinden, Yunzhou Cheng, John D Rolston, Loren Rieth, Martin D Dawson, Keith Mathieson, Steve Blair, Alessandra Angelucci
Optogenetics has transformed studies of neural circuit function, but remains challenging to apply to non-human primates (NHPs). A major challenge is delivering intense, spatiotemporally-precise, patterned photostimulation across large volumes in deep tissue. Such stimulation is critical, for example, to modulate selectively deep-layer corticocortical feedback circuits. To address this need, we have developed the Utah Optrode Array (UOA), a 10×10 glass needle waveguide array fabricated atop a novel opaque optical interposer, and bonded to an electrically addressable µLED array...
March 14, 2024: Communications Biology
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