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https://www.readbyqxmd.com/read/29352061/what-to-do-about-fibrin-rich-tough-clots-comparing-the-solitaire-stent-retriever-with-a-novel-geometric-clot-extractor-in-an-in-vitro-stroke-model
#1
Vernard S Fennell, Swetadri Vasan Setlur Nagesh, Karen M Meess, Liza Gutierrez, Rhys H James, Michael E Springer, Adnan H Siddiqui
BACKGROUND: Despite advances in revascularization tools for large vessel occlusion presenting as acute ischemic stroke, a significant subset of clots remain recalcitrant to current strategies. We assessed the effectiveness of a novel thrombectomy device that was specifically designed to retrieve resistant fibrin rich clots, the geometric clot extractor (GCE; Neuravi, Galway, Ireland), in an in vitro cerebrovascular occlusion stroke model. METHODS: After introducing fibrin rich clot analogues into the middle cerebral artery of the model, we compared the rates of recanalization between GCE and Solitaire flow restoration stent retriever (SR; Medtronic, Minneapolis, Minnesota, USA; control group) cases...
January 19, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29351373/a-facile-space-confined-solid-phase-sulfurization-strategy-for-growth-of-high-quality-ultrathin-molybdenum-disulfide-single-crystals
#2
Dawei Li, Zhiyong Xiao, Sai Mu, Fei Wang, Ying Liu, Jingfeng Song, Xi Huang, Lijia Jiang, Jun Xiao, Lei Liu, Stephen Ducharme, Bai Cui, Xia Hong, Lan Jiang, Jean-Francois Silvain, Yongfeng Lu
Single-crystal transition metal dichalcogenides (TMDs) and TMD-based hetero-junctions have recently attracted significant research and industrial interest owing to their intriguing optical and electrical properties. However, the lack of a simple, low-cost, environmentally friendly, synthetic method and a poor understanding of the growth mechanism post a huge challenge to implementing TMDs in practical applications. In this work, we developed a novel approach for direct formation of high-quality, monolayer and few-layer MoS2 single crystal domains via a single-step rapid thermal processing of a sandwiched reactor with sulfur and molybdenum (Mo) film in a confined reaction space...
January 19, 2018: Nano Letters
https://www.readbyqxmd.com/read/29351223/a-novel-walking-detection-and-step-counting-algorithm-using-unconstrained-smartphones
#3
Xiaomin Kang, Baoqi Huang, Guodong Qi
Recently, with the development of artificial intelligence technologies and the popularity of mobile devices, walking detection and step counting have gained much attention since they play an important role in the fields of equipment positioning, saving energy, behavior recognition, etc. In this paper, a novel algorithm is proposed to simultaneously detect walking motion and count steps through unconstrained smartphones in the sense that the smartphone placement is not only arbitrary but also alterable. On account of the periodicity of the walking motion and sensitivity of gyroscopes, the proposed algorithm extracts the frequency domain features from three-dimensional (3D) angular velocities of a smartphone through FFT (fast Fourier transform) and identifies whether its holder is walking or not irrespective of its placement...
January 19, 2018: Sensors
https://www.readbyqxmd.com/read/29351185/brief-report-lead-levels-in-selected-electronic-cigarettes-from-canada-and-the-united-states
#4
Zachary R Dunbar, Ananth Das, Richard J O'Connor, Maciej L Goniewicz, Binnian Wei, Mark J Travers
Few published studies have investigated the presence of lead in the e-liquid of electronic nicotine delivery systems (ENDS). Lead inhalation is associated with increased risk of stroke, heart disease, and other diseases. This study used a novel application of graphite furnace technology to compare the concentration of lead between e-liquids of different packaging and product designs using e-liquids that are or were commercially available in the United States and Canada. Eleven nicotine-free disposable ENDS devices and 12 bottled refill solutions that contained nicotine were purchased from retailers in Canada and the United States between 2015 and 2017...
January 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29350946/electrical-control-of-structural-and-physical-properties-via-strong-spin-orbit-interactions-in-sr_-2-iro_-4
#5
G Cao, J Terzic, H D Zhao, H Zheng, L E De Long, Peter S Riseborough
Electrical control of structural and physical properties is a long-sought, but elusive goal of contemporary science and technology. We demonstrate that a combination of strong spin-orbit interactions (SOI) and a canted antiferromagnetic Mott state is sufficient to attain that goal. The antiferromagnetic insulator Sr_{2}IrO_{4} provides a model system in which strong SOI lock canted Ir magnetic moments to IrO_{6} octahedra, causing them to rigidly rotate together. A novel coupling between an applied electrical current and the canting angle reduces the Néel temperature and drives a large, nonlinear lattice expansion that closely tracks the magnetization, increases the electron mobility, and precipitates a unique resistive switching effect...
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29350935/reconfigurable-skyrmion-logic-gates
#6
Shijiang Luo, Min Song, Xin Li, Yue Zhang, Jeongmin Hong, Xiaofei Yang, Xuecheng Zou, Nuo Xu, Long You
Magnetic skyrmion, a nano-sized spin texture with topological property, has become an area of significant interest due to the scientific insight that it can provide and also its potential impact on applications such as ultra low-energy and ultra high-density logic gates. In the quest for the reconfiguration of single logic device and the implementation of the complete logic functions, a novel reconfigurable skyrmion logic (RSL) is proposed and verified by micromagnetic simulations. Logic functions including AND, OR, NOT, NAND, NOR, XOR, and XNOR are implemented in the ferromagnetic (FM) nanotrack by virtue of various effects including spin orbit torque, skyrmion Hall effect, skyrmion-edge repulsions, and skyrmion-skyrmion collision...
January 19, 2018: Nano Letters
https://www.readbyqxmd.com/read/29350931/multiscale-and-multistep-ordering-of-flow-induced-nucleation-of-polymers
#7
Kunpeng Cui, Zhe Ma, Nan Tian, Fengmei Su, Dong Liu, Liangbin Li
Flow-induced crystallization (FIC) is a typical nonequilibrium phase transition and a core industry subject for the largest group of commercially useful polymeric materials: semicrystalline polymers. A fundamental understanding of FIC can benefit the research of nonequilibrium ordering in matter systems and help to tailor the ultimate properties of polymeric materials. Concerning the crystallization process, flow can accelerate the kinetics by orders of magnitude and induce the formation of oriented crystallites like shish-kebab, which are associated with the major influences of flow on nucleation, that is, raised nucleation density and oriented nuclei...
January 19, 2018: Chemical Reviews
https://www.readbyqxmd.com/read/29350732/complete-amplitude-and-phase-control-of-light-using-broadband-holographic-metasurfaces
#8
Gun-Yeal Lee, Gwanho Yoon, Seung-Yeol Lee, Hansik Yun, Jaebum Cho, Kyookeun Lee, Hwi Kim, Junsuk Rho, Byoungho Lee
Reconstruction of light profiles with amplitude and phase information, called holography, is an attractive optical technology with various significant applications such as three-dimensional imaging and optical data storage. Subwavelength spatial control of both amplitude and phase of light is an essential requirement for an ideal hologram. However, traditional holographic devices suffer from their restricted capabilities of incomplete modulation in both amplitude and phase of visible light; this results in sacrifice of optical information and undesirable occurrences of critical noises in holographic images...
January 19, 2018: Nanoscale
https://www.readbyqxmd.com/read/29350602/a-novel-approach-to-32-channel-peripheral-nervous-system-myelin-imaging-in-vivo-with-single-axon-resolution
#9
Joey Grochmal, Wulin Teo, Hardeep Gambhir, Ranjan Kumar, Jo Anne Stratton, Raveena Dhaliwal, Craig Brideau, Jeff Biernaskie, Peter K Stys, Rajiv Midha
OBJECTIVE Intravital spectral imaging of the large, deeply situated nerves in the rat peripheral nervous system (PNS) has not been well described. Here, the authors have developed a highly stable platform for performing imaging of the tibial nerve in live rodents, thus allowing the capture of high-resolution, high-magnification spectral images requiring long acquisition times. By further exploiting the qualities of the topically applied myelin dye Nile red, this technique is capable of visualizing the detailed microenvironment of peripheral nerve demyelination injury and recovery, while allowing us to obtain images of exogenous Schwann cell myelination in a living animal...
January 19, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29350200/leaf-templated-microwell-integrated-microfluidic-chips-for-high-throughput-cell-experiments
#10
Mao Mao, Jiankang He, Yongjie Lu, Xiao Li, Tianjiao Li, Wenxing Zhou, Dichen Li
As an alternative to conventional cell culture and animal testing, organ-on-a-chip is applied to study the biological phenomena of organ development and disease, as well as the interactions between human tissues and external stimuli such as chemicals, forces and electricity. The pattern design of microfluidic channel is one of the key approaches to regulate cell growth and differentiation, because these channels work as a crucial vasculature system to control the fluidic flow throughout the organ-on-a-chip device...
January 19, 2018: Biofabrication
https://www.readbyqxmd.com/read/29350193/layer-structured-bismuth-selenides-bi2se3-and-bi3se4-for-high-energy-and-flexible-all-solid-state-micro-supercapacitors
#11
Chunxue Hao, Lidan Wang, Fusheng Wen, Jianyong Xiang, Lei Li, Wentao Hu, Zhongyuan Liu
In this work, bismuth selenides (Bi2Se3 and Bi3Se4), both of which have a layered rhombohedral crystal structure, have been found to be useful as electrode materials for supercapacitor applications. In a liquid electrolyte system (6M KOH), Bi2Se3 nanoplates exhibit much better performance as an electrode material than Bi3Se4 nanoparticles do, delivering a higher specific capacitance (272.9 F g-1) than that of Bi3Se4 (193.6 F g-1) at 5 mV s-1. This result may be attributed to the fact that Bi2Se3 nanoplates possess more active electrochemical surfaces for the reversible surface redox reactions owing to their planar quintuple stacked layers (septuple layers for Bi3Se4)...
January 19, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29350183/integrated-biocircuits-engineering-functional-multicellular-circuits-and-devices
#12
Jordan Prox, Tory Smith, Chad Holl, Nick Chehade, Liang Guo
Novel in vitro platforms are currently revolutionizing the study and reconstruction of cellular circuitry to bypass the pertaining obstacles of data retrieval in vivo. While earlier approaches have provided great insights into culturing circuits in planar dissociated cell culture systems, the lack of full control over network activity and formation limits our understanding of their functionality. Thus, integrating various controllable parameters are required in creating a suitable microenvironment including cell patterning, highly-specified electrical and chemical stimuli, and rational circuit formation via logic functions...
January 19, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29350084/exploring-assistive-technology-use-to-support-cognition-in-college-students-with-histories-of-mild-traumatic-brain-injury
#13
Jessica Brown, Madeline Wollersheim
PURPOSE: College students with mild traumatic brain injury (mTBI) may experience chronic cognitive deficits necessitating use of external supports for daily task completion. The purpose of this study was to explore cognitive support system selection and use by students with histories of mTBI when completing novel prospective memory tasks. MATERIALS AND METHODS: We implemented a multiple case study, sequential explanatory mixed-methods design with three participants...
January 19, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29349805/hybrid-continuous-flow-total-artificial-heart
#14
Carson Fox, Steven Chopski, Nohra Murad, Paul Allaire, Robert Mentzer, Joseph Rossano, Francisco Arabia, Amy Throckmorton
Clinical studies using total artificial hearts (TAHs) have demonstrated that pediatric and adult patients derive quality-of-life benefits from this form of therapy. Two clinically-approved TAHs and other pumps under development, however, have design challenges and limitations, including thromboembolic events, neurologic impairment, infection risk due to large size and percutaneous drivelines, and lack of ambulation, to name a few. To address these limitations, we are developing a hybrid-design, continuous-flow, implantable or extracorporeal, magnetically-levitated TAH for pediatric and adult patients with heart failure...
January 18, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29349636/effects-of-asymmetric-local-joule-heating-on-silicon-nanowire-based-devices-formed-by-dielectrophoresis-alignment-across-pt-electrodes
#15
Hsiang-Hsi Ho, Chun-Lung Lin, Wei-Che Tsai, Liang-Zheng Hong, Cheng-Han Lyu, Hsun-Feng Hsu
We demonstrate the fabrication and characterization of silicon nanowire-based devices in metal-nanowire-metal configuration using direct current dielectrophoresis. The current-voltage characteristics of the devices were found rectifying, and their direction of rectification could be determined by voltage sweep direction due to the asymmetric Joule heating effect that occurred in the electrical measurement process. The photosensing properties of the rectifying devices were investigated. It reveals that when the rectifying device was in reverse-biased mode, the excellent photoresponse was achieved due to the strong built-in electric field at the junction interface...
January 16, 2018: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29349601/prospective-feasibility-analysis-of-a%C3%A2-novel-off-line-approach-for-mr-guided-radiotherapy
#16
Tilman Bostel, Asja Pfaffenberger, Stefan Delorme, Constantin Dreher, Gernot Echner, Peter Haering, Clemens Lang, Mona Splinter, Frederik Laun, Marco Müller, Oliver Jäkel, Jürgen Debus, Peter E Huber, Florian Sterzing, Nils H Nicolay
BACKGROUND: The present work aimed to analyze the feasibility of a shuttle-based MRI-guided radiation therapy (MRgRT) in the treatment of pelvic malignancies. PATIENTS AND METHODS: 20 patients with pelvic malignancies were included in this prospective feasibility analysis. Patients underwent daily MRI in treatment position prior to radiotherapy at the German Cancer Research Center. Positional inaccuracies, time and patient compliance were assessed for the application of off-line MRgRT...
January 18, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29348687/far-field-superfocusing-along-with-enhanced-near-field-emission-from-hybrid-spiral-plasmonic-lens-inscribed-with-nano-corrals-slit-diffractor
#17
Priyanshu Jain, Tanmoy Maiti
Here, we have numerically calculated electric field intensity and phase of the emission from various hybrid spiral plasmonic lenses (HSPL) in near field as well as in far-field. We have proposed a novel HSPL inscribed with nano corrals slit (NCS) and compared its focusing ability with other HSPLs inscribed with circular slit and circular grating. With the use of nano corrals slit, we have been able to improve light intensity in the far-field without compromising near-field intensity. Our NCS-HSPL outperforms other HSPLs and standalone SPL in near-field as well as far-field...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348639/evidence-of-local-structural-influence-on-the-shape-driven-magnetic-anisotropy-in-electronically-excited-ni-nanoparticles-embedded-in-sio2-matrix
#18
Debalaya Sarker, Saswata Bhattacharya, H Kumar, Pankaj Srivastava, Santanu Ghosh
The reliance of modern electronic era on ultrafast data recording has made the search for novel tools to tune nano-scale magnetic-anisotropy (MA) never-ending. We demonstrate a strong correlation between the spin-spin interactions, local atomic structure and the MA of Ni nanoparticles (NPs) embedded inside SiO2 matrix under swift heavy ion (SHI) irradiation. In contrast to traditional understandings, MA in Ni NPs along with their aspect ratio, first increases upto 5 × 1013 ions/cm2 SHI fluence (5e13) and gets reduced at highest fluence...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348589/novel-miniature-membrane-active-lipopeptidomimetics-against-planktonic-and-biofilm-embedded-methicillin-resistant-staphylococcus-aureus
#19
Seema Joshi, Sana Mumtaz, Jyotsna Singh, Santosh Pasha, Kasturi Mukhopadhyay
Escalating multidrug resistance and highly evolved virulence mechanisms have aggravated the clinical menace of methicillin-resistant Staphylococcus aureus (MRSA) infections. Towards development of economically viable staphylocidal agents here we report eight structurally novel tryptophan-arginine template based peptidomimetics. Out of the designed molecules, three lipopeptidomimetics (S-6, S-7 and S-8) containing 12-amino dodecanoic acid exhibited cell selectivity and good to potent activity against clinically relevant pathogens MRSA, methicillin-resistant Staphylococcus epidermidis and vancomycin-resistant Enterococcus faecium (MIC: 1...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348436/high-throughput-analysis-using-non-depletive-spme-challenges-and-applications-to-the-determination-of-free-and-total-concentrations-in-small-sample-volumes
#20
Ezel Boyacı, Barbara Bojko, Nathaly Reyes-Garcés, Justen J Poole, Germán Augusto Gómez-Ríos, Alexandre Teixeira, Beate Nicol, Janusz Pawliszyn
In vitro high-throughput non-depletive quantitation of chemicals in biofluids is of growing interest in many areas. Some of the challenges facing researchers include the limited volume of biofluids, rapid and high-throughput sampling requirements, and the lack of reliable methods. Coupled to the above, growing interest in the monitoring of kinetics and dynamics of miniaturized biosystems has spurred the demand for development of novel and revolutionary methodologies for analysis of biofluids. The applicability of solid-phase microextraction (SPME) is investigated as a potential technology to fulfill the aforementioned requirements...
January 18, 2018: Scientific Reports
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