keyword
MENU ▼
Read by QxMD icon Read
search

anal intraepithelial neoplasia

keyword
https://www.readbyqxmd.com/read/28255426/anal-intraepithelial-neoplasia-a-review-of-diagnosis-and-management
#1
REVIEW
Joseph R Roberts, Lacey L Siekas, Andrew M Kaz
Anal intraepithelial neoplasia (AIN) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. Although anal cancer is relatively uncommon, rates of this malignancy are steadily rising in the United States, and among certain high risk populations the incidence of anal cancer may exceed that of colon cancer. Risk factors for AIN and anal cancer consist of clinical factors and behaviors that are associated with the acquisition and persistence of human papilloma virus (HPV) infection. The strongest HPV-associated risk factors are HIV infection, receptive anal intercourse, and high risk sexual behavior...
February 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28252530/risk-factors-of-high-grade-anal-intraepithelial-neoplasia-recurrence-in-hiv-infected-men-who-have-sex-with-men
#2
Joaquin Burgos, Adria Curran, Stefania Landolfi, Ana Guelar, Lucia Miguel, MCarmen Dinares, Judith Villar, Jordi Navarro, Javier Hernandez-Losa, Vicenç Falcó
OBJECTIVE: To assess risk factors of high-grade anal intraepithelial neoplasia (HGAIN) recurrence in a cohort of HIV-infected men who have sex with men (MSM). DESIGN AND METHODS: Consecutive HIV-infected 100 MSM with a history of successfully treated intra-anal HGAIN with electrocautery were followed with anal cytology, human papillomavirus (HPV) determination, and high-resolution anoscopy (HRA) at 3-6 month intervals. HGAIN recurrence was analyzed using Kaplan-Meier analysis...
March 1, 2017: AIDS
https://www.readbyqxmd.com/read/28229612/preliminary-results-of-a-screening-program-for-anal-cancer-and-its-precursors-for-hiv-infected-men-who-have-sex-with-men-in-vigo-spain
#3
Mauricio Iribarren Díaz, Antonio Ocampo Hermida, Joaquín González-Carreró Fojón, Rebeca Longueira Suárez, Alberto Rivera Gallego, Enrique Casal Núñez, Antón Ocampo Álvarez, Edward Cachay
BACKGROUND: Men who have sex with men (MSM) infected with human immunodeficiency virus (HIV) have the highest risk of developing anal cancer (AC). The objective of this study was to describe our screening implementation program in this population, and report the prevalence of human papillomavirus (HPV) anal infection, and cytological and histological findings in a Spanish medium-size community (Vigo, Spain). METHOD: Prospective cohort analysis of 240 HIV-infected MSM...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28161543/anal-study-in-immunocompetent-women-with-human-papillomavirus-related-lower-genital-tract-pathology
#4
Concepción Donaire, Marcos Reillo, Juan C Martínez-Escoriza, José A López-Fernández
OBJETIVE: To estimate the prevalence of anal dysplasia in immunocompetent women with cervical intraepithelial dysplasia. STUDY DESIGN: We did a prospective cohort study, in which we enrolled 166 women with gynecological pathology related to human papilloma virus (HPV) infection. All patients underwent an anal cytology and HPV detection. Statistical analysis with a 95% confidence interval was used for prevalence calculations. A Χ2 test and Fisher's exact one were used to determine differences between groups of qualitative variables...
January 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28160456/primary-anorectal-mucosal-melanoma-detected-by-anorectal-cytology
#5
Ryan Paul Lau, Jeanine Chiaffarano, Melissa Alexander, Jolene Octavius, Omar Azar, Yan Shi, Melissa Yee-Chang
The detection of primary anorectal melanoma on anal cytology is a rare and challenging diagnosis. We report a case where anorectal cytology showed isolated malignant cells with oval nuclei, prominent nucleoli, and elongated wispy cytoplasmic projections. There was no evidence of squamous dysplasia or melanin pigment identified. To the best of our knowledge, this is the first reported case of a primary anorectal melanoma detected in anorectal cytology. Detection of malignancies other than squamous cell carcinoma can be seen on anorectal cytology and should be considered when there is no evidence of anal intraepithelial neoplasia...
February 3, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28121939/multiple-preinvasive-and-invasive-hpv-related-lesions-of-the-anogenital-tract-in-a-female-patient-with-hiv-infection-a-case-report
#6
Nicolò Clemente, Lara Alessandrini, Emanuela Vaccher, Antonino De Paoli, Monica Buttignol, Vincenzo Canzonieri, Francesco Sopracordevole
RATIONALE: Patients with human immunodeficiency virus (HIV) infection have been shown to be at increased risk for high-risk human papillomavirus (HR-HPV) infection of the anogenital tract. Furthermore, in the last decades, the introduction of highly active antiretroviral therapy (HAART) has increased the longevity of these patients who now live long enough to develop HPV-related cancers; hence, the impact of HPV infection on HIV-positive patients is of increasing concern. PATIENT CONCERNS: We reported the case of an HIV-positive female patient on HAART with a good virological and immunological response and with a long history of HPV-related intraepithelial and invasive lesions of the anogenital tract...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28098569/human-papillomavirus-genotyping-of-incidental-malignant-and-premalignant-lesions-on-hemorrhoidectomy-specimens
#7
Yiang Hui, M Ruhul Quddus, Jayasimha N Murthy, Dongfang Yang, C James Sung, Shaolei Lu, Murray B Resnick, Li Juan Wang
Routine histopathologic examination of hemorrhoidectomy specimens is controversial having been described as not useful and expensive with few of these common cases demonstrating incidental lesions. However, unexpected premalignant and malignant lesions have been detected on excised hemorrhoids. The high-risk human papillomavirus (HR-HPV) types associated with these incidentally identified high-grade lesions are presently unknown. We aimed to identify cases of incidental high-grade anal intraepithelial neoplasia (HG-AIN) and anal squamous cell carcinoma incidentally discovered on hemorrhoidectomy specimens, genotype HR-HPVs from these lesions, and assess p53 and p16 expression by immunohistochemistry to identify risk factors for their development...
March 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27986194/cost-effectiveness-study-of-hpv-vaccination-as-a-primary-prevention-strategy-for-anal-cancer-in-hiv-positive-men-in-chile
#8
Constanza Vargas Parada, J Lennert Veerman
BACKGROUND: Most anal cancers are caused by the human papilloma virus (HPV) infection. The incidence is increasing, especially in high-risk individuals such as HIV-positive men. Evidence shows that the new quadrivalent HPV vaccine reduces the rates of anal intraepithelial neoplasia among men who have sex with men. OBJECTIVE: To determine whether vaccinating against HPV-related anal cancer is cost-effective in HIV-positive men in Chile. METHODS: A cost-effectiveness analysis was conducted by constructing a cohort multistate life-table-based Markov model in MS Excel in which the prevention of HPV infection was expected to influence the incidence of anal cancer in HIV-positive men...
December 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27917295/circulating-human-papillomavirus-dna-detected-using-droplet-digital-pcr-in-the-serum-of-patients-diagnosed-with-early-stage-human-papillomavirus-associated-invasive-carcinoma
#9
Emmanuelle Jeannot, Véronique Becette, Maura Campitelli, Marie-Ange Calméjane, Emmanuelle Lappartient, Evelyne Ruff, Stéphanie Saada, Allyson Holmes, Dominique Bellet, Xavier Sastre-Garau
Specific human papillomavirus genotypes are associated with most ano-genital carcinomas and a large subset of oro-pharyngeal carcinomas. Human papillomavirus DNA is thus a tumour marker that can be detected in the blood of patients for clinical monitoring. However, data concerning circulating human papillomavirus DNA in cervical cancer patients has provided little clinical value, due to insufficient sensitivity of the assays used for the detection of small sized tumours. Here we took advantage of the sensitive droplet digital PCR method to identify circulating human papillomavirus DNA in patients with human papillomavirus-associated carcinomas...
October 2016: Journal of Pathology. Clinical Research
https://www.readbyqxmd.com/read/27845952/human-papillomavirus-as-a-cause-of-anal-cancer-and-the-role-of-screening
#10
Karien C M Gosens, Olivier Richel, Jan M Prins
PURPOSE OF REVIEW: Anal cancer is a serious health problem in HIV-positive men who have sex with men, and precursor lesions, anal intraepithelial neoplasia, are well defined. Given the similarities with cervical cancer, screening for and treatment of anal intraepithelial neoplasia might prevent anal cancer. Screening programmes should meet the Wilson and Jungner criteria. We used these criteria to evaluate the current body of evidence supporting a screening programme for anal dysplasia...
February 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27806411/anal-chromoendoscopy-using-gastroenterological-video-endoscopes-a-new-method-to-perform-high-resolution-anoscopy-for-diagnosing-intraepithelial-neoplasia-and-anal%C3%A2-carcinoma-in-hiv-infected-patients
#11
Mark Oette, Ulrike Wieland, Marko Schünemann, Johannes Haes, Stefan Reuter, Björn Erik Ole Jensen, Abdurrahman Sagir, Herbert Pfister, Dieter Häussinger
Introduction Anal carcinoma represents an increasing problem in HIV-infected patients. Anal intraepithelial neoplasia (AIN), the precursor lesion, is currently diagnosed by high-resolution anoscopy (HRA) using optical magnification derived from gynecological colposcopy. This prospective study evaluates anal chromoendoscopy (ACE) using standard gastroenterological video-endoscopes in diagnosing AIN. Methods After clinical examination, proctoscopy and surface staining with acetic acid followed by Lugol's solution, ACE was performed with a mucosectomy cap on the tip of the endoscope...
January 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27772624/human-papillomavirus-in-kidney-transplant-recipients
#12
REVIEW
Peter V Chin-Hong
Human papillomavirus (HPV) is a common infection in kidney transplant recipients. HPV causes cervical, anal, vulvar, vaginal, penile and head and neck cancers. Kidney transplant recipients have a disproportionate burden of disease given prolonged immunosuppression. Given the long pre-invasive state of precancer lesions such as cervical intraepithelial neoplasia (CIN) and anal intraepithelial neoplasia (AIN) most HPV-cancers are preventable with screening and targeted treatment of disease. Pre-transplant vaccination of age-eligible kidney transplant recipients is otherwise ideal...
September 2016: Seminars in Nephrology
https://www.readbyqxmd.com/read/27770248/a-trial-of-radiofrequency-ablation-for-anal-intraepithelial-neoplasia
#13
Robert N Goldstone, Shirin R Hasan, Steven Drury, Teresa M Darragh, Annemieke van Zante, Stephen E Goldstone
PURPOSE: Radiofrequency ablation (RFA) effectively treats esophageal high-grade dysplasia, but its efficacy in treating anal canal high-grade squamous intraepithelial lesions (HSILs) is unsubstantiated. This prospective study assessed the safety and efficacy of applying hemi-circumferential RFA to anal canal HSIL. METHODS: Twenty-one HIV-negative participants with HSIL occupying ≤ half the anal canal circumference were treated with hemi-circumferential anal canal RFA...
October 21, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27749636/anal-intraepithelial-neoplasia
#14
Michele Limoges-Gonzalez, Amar Al-Juburi
Anal squamous cell cancer (SCC) is a relatively uncommon cancer in the United States. Anal SCC has long been associated with human immunodeficiency virus (HIV) positivity and/or men who have sex with men. The incidence of anal SCC has been increasing in both genders regardless of HIV status. Few clinicians are aware that white women, when not controlling for gender and sexual preference together, have the highest incidence of anal SCC. Anal intraepithelial neoplasia (AIN), dysplastic cells of the anal canal due to human papilloma virus infection, is believed to be the precursor to anal SCC...
March 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27708526/endoscopic-submucosal-dissection-for-anal-intraepithelial-neoplasia
#15
Junichi Miyazaki, Noriya Uedo, Zhao Liang Li, Shohei Matsuo
No abstract text is available yet for this article.
October 2016: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/27618320/tumors-and-tumorlike-conditions-of-the-anal-canal-and-perianal-region-mr-imaging-findings
#16
Venkateswar R Surabhi, Christine O Menias, Ahmed M Amer, Mohamed Elshikh, Venkata S Katabathina, Amy K Hara, William C Baughman, Ania Kielar, Khaled M Elsayes, Cary L Siegel
Tumors and tumorlike conditions of the anus and perianal region originate from the anal canal and anal margin or result from direct extension of tumors from adjacent organs. The anatomy of the anal canal is complex, and its different histologic characteristics can lead to diverse pathologic conditions. The anal canal extends from the anorectal junction to the anal verge. The World Health Organization classification of anal canal tumors includes (a) anal intraepithelial neoplasia, the precursor of squamous cell carcinoma (SCC), and (b) invasive tumors...
September 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27600328/screening-for-anal-intraepithelial-neoplasia-high-resolution-anoscopy-guided-biopsy-of-the-anal-canal
#17
J B Repiso Jiménez, L Padilla España, T Fernández Morano, M de Troya Martín
No abstract text is available yet for this article.
January 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/27561134/2016-ians-international-guidelines-for-practice-standards-in-the-detection-of-anal-cancer-precursors
#18
Richard John Hillman, Tamzin Cuming, Teresa Darragh, Mayura Nathan, Michael Berry-Lawthorn, Stephen Goldstone, Carmella Law, Joel Palefsky, Luis F Barroso, Elizabeth A Stier, Céline Bouchard, Justine Almada, Naomi Jay
OBJECTIVES: To define minimum standards for provision of services and clinical practice in the investigation of anal cancer precursors. METHODS: After initial face to face meetings of experts at the International Papillomavirus meeting in Lisbon, September 17 to 21, 2015, a first version was drafted and sent to key stakeholders. A complete draft was reviewed by the Board of the International Anal Neoplasia Society (IANS) and uploaded to the IANS Web site for all members to provide comments...
October 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27507125/-early-diagnosis-of-anal-intraepithelial-neoplasia-associated-with-human-papillomavirus-what-is-the-best-strategy
#19
Joaquin Burgos, Adrian Curran
No abstract text is available yet for this article.
August 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27505112/progression-from-perianal-high-grade-anal-intraepithelial-neoplasia-to-anal-cancer-in-hiv-positive-men-who-have-sex-with-men
#20
Jill Tinmouth, Valentina Peeva, Henok Amare, Sandra Blitz, Janet Raboud, Marie Sano, Leah Steele, Irving E Salit
BACKGROUND: High-grade intraepithelial neoplasia is known to progress to invasive squamous-cell carcinoma of the anus. There are limited reports on the rate of progression from high-grade intraepithelial neoplasia to anal cancer in HIV-positive men who have sex with men. OBJECTIVES: The purpose of this study was to describe in HIV-positive men who have sex with men with perianal high-grade intraepithelial neoplasia the rate of progression to anal cancer and the factors associated with that progression...
September 2016: Diseases of the Colon and Rectum
keyword
keyword
81494
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"