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peritoneal dialysis and diabetes

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https://www.readbyqxmd.com/read/28791842/dialysis-vintage-and-cardiovascular-injury-as-factors-influencing-long-term-survival-in-peritoneal-dialysis-and-hemodialysis
#1
Krzysztof Hoppe, Krzysztof Schwermer, Anna Olewicz-Gawlik, Patrycja Klysz, Anna Kawka, Ewa Baum, Dorota Sikorska, Katarzyna Ścigacz, Magdalena Roszak, Bengt Lindholm, Krzysztof Pawlaczyk, Andrzej Oko
BACKGROUND: Cardiovascular (CV) incidents are the major cause of mortality in maintenance dialysis (MD) patients undergoing peritoneal dialysis (PD) or hemodialysis (HD). CV injury indicators may be useful to investigate the dialysis modality influence on survival. OBJECTIVES: The aim of this study was to compare selected laboratory and echocardiographic (ECHO) markers of CV injury in terms of dialysis vintage (DV), CV-related mortality and all-cause mortality. MATERIAL AND METHODS: The study involved 301 patients on HD (n = 301) and PD (n = 58), who were divided into subgroups according to DV...
March 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28765166/impact-of-the-karnofsky-performance-status-on-survival-and-its-dynamics-during-the-terminal-year-of-peritoneal-dialysis-patients
#2
Ana P Modesto, Len Usvyat, Viviane Calice-Silva, Dandara N Spigolon, Ana E Figueiredo, Thyago P de Moraes, Marcia Olandoski, Silvia E Shimakura, Pasqual Barretti, Peter Kotanko, Roberto Pecoits-Filho
BACKGROUND: Simple and low-cost tools to monitor the risk profile of patients on peritoneal dialysis (PD) at high risk of complications and mortality are scarce. One of the tools available to monitor the variation in vitality and dependence levels is the Karnofsky performance status (KPS). This study analyzed the average trends and variation of KPS during the 12 months before death and its independent value in predicting patients' survival. METHODS: The data were compiled from the BRAZPD II multi-center study, performed in Brazil between 2004 and 2011...
August 1, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28760111/differences-in-prevalence-of-muscle-wasting-in-patients-receiving-peritoneal-dialysis-per-dual-energy-x-ray-absorptiometry-due-to-variation-in-guideline-definitions-of-sarcopenia
#3
Rachel Hung, Bethany Wong, Gabrielle Goldet, Andrew Davenport
BACKGROUND: Muscle wasting is associated with increased risk for mortality. There is no agreed universal definition for muscle wasting (sarcopenia), and we wished to determine whether using different criteria altered the prevalence in patients treated by peritoneal dialysis. METHODS: We measured lean body and appendicular lean mass indices in 325 outpatients by dual-energy x-ray absorptiometry, comparing muscle mass with that used to define muscle wasting (sarcopenia) by various clinical guideline publications...
August 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28755902/low-triiodothyronine-is-associated-with-elevation-of-n-terminal-pro-brain-natriuretic-peptide-nt-probnp-and-mortality-in-dialysis-patients
#4
María Del Carmen Prado-Uribe, María-de-Jesús Ventura, Marcela Ávila-Díaz, Carmen J Mora, Antonio Méndez-Durán, Diana Villanueva-Noches, Alejandra Cisneros, Begoña Ilabaca, Alfonso Cueto-Manzano, Fernando García-Contreras, Bengt Lindholm, Elvia García-López, Ramón Paniagua
BACKGROUND: Low thyroid hormone (TH) levels and myocardial damage are common in dialysis patients and are associated with mortality. However, little is known about the role of THs on myocardial damage as has been described in primary thyroid diseases. The aim of this study was to explore the potential relationship between low total triiodothyronine (total T3) and biomarkers of myocardial damage and the effect of their interaction on mortality, to ascertain if cardiovascular damage is the link between low THs and the risk of death in dialysis patients with CKD...
July 26, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28748892/clinical-profile-of-geriatric-acute-kidney-injury-in-a-tertiary-care-center-from-south-india
#5
Eshwarappa Mahesh, Praveen Nallamuthu, Mahesh Kumar, Parampalli Rakesh Madhyastha, Gurudev Konanna
The incidence of acute kidney injury (AKI) is high in the elderly, who comprise an ever-growing segment of the population. Elderly patients pose a different set of diagnostic and therapeutic challenge owing to their associated comorbidities. AKI in the elderly is associated with an increased risk of mortality, morbidity, prolonged length of stay, and progression to chronic kidney disease. Data regarding the clinical profile of AKI in the elderly from the South Indian population are limited. Hence, we present this analysis of the etiological and prognostic factors associated with AKI in elderly population from South India...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748880/incident-elderly-patients-on-peritoneal-dialysis-epidemiological-characteristics-and-modality-impact-on-survival-time
#6
Marcia R G Franco, Marcus G Bastos, Abdul R Qureshi, Alyne Schreider, Kleyton de Andrade Bastos, Jose C Divino-Filho, Natalia M S Fernandes
Aging of the population and the increased prevalence of diseases such as diabetes and arterial hypertension result in an increasing need of dialysis treatment. Herein we describe a cohort of elderly patients on peritoneal dialysis (PD) and assess the influence of the modality on the long-term survival. Out of a multicenter prospective cohort of 2,144 BRAZPD PD incident patients during a period from December 2004 to October 2007, 762 elderly adults, defined as patients ≥65-year-old, were eligible for the study, 413 started on automated PD (APD) and 349 on continuous ambulatory PD (CAPD)...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28725317/prevalence-of-metabolic-syndrome-among-the-end-stage-renal-disease-patients-on-hemodialysis
#7
Khaled A Alswat, Awwadh Althobaiti, Khulod Alsaadi, Amaal Saeed Alkhaldi, Maryam Mutlaq Alharthi, Walaa Abduraheem Abuharba, Ahmed A Alzaidi
BACKGROUND: Patients with metabolic syndrome (MetS) have a 2.6-fold greater risk of incident chronic kidney disease (CKD). The primary goal of this study was to assess the prevalence of MetS in patients with end-stage renal disease (ESRD) who are on hemodialysis (HD) and the impact of MetS presence on HD-related outcomes. METHODS: This is a cross-sectional study conducted in the Dialysis Center, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia. It was conducted among ESRD patients that attended the Dialysis Center between August 2013 and September 2016...
August 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28714271/influence-of-residual-renal-function-in-carotid-modeling-as-a-marker-of-early-atherosclerosis-in-dialysis-patients
#8
Merita Rroji, Nereida Spahia, Saimir Seferi, Myftar Barbullushi, Goce Spasovski
Atherosclerosis is frequently present in patients with chronic kidney disease (CKD) treated with dialysis. We evaluated the association between residual renal function (RRF), phosphate level, inflammation and other risk factors in carotid modeling as a marker of early atherosclerosis in peritoneal dialysis (PD) compared with hemodialysis (HD) patients. We studied 39 stable PD and 53 HD patients on renal replacement therapy (RRT) for 3 to 36 months duration. B-mode ultrasonography was used to determine carotid artery intima media thickness (CIMT)...
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28708216/colonoscopy-in-automated-peritoneal-dialysis-patients-value-of-prophylactic-antibiotics-a-prospective-study-on-a-single-antibiotic
#9
Abdullah K Al-Hwiesh, Ibrahiem S Abdul-Rahman, Mohammad A Hussameldeen, Nadia Al-Audah, Abdalla Abdelrahman, Hala M Moaigel, Tamer El-Salamony, Abdul-Salam Noor, Aisha Al-Osail, Dalal Al-Sayel, Nourah Al-Dossari
OBJECTIVE: To evaluate the need for prophylactic antibiotics in automated peritoneal dialysis (APD) patients undergoing flexible colonoscopy. PATIENTS AND METHODS: A total of 93 patients on automated peritoneal dialysis (APD) undergoing diagnostic colonoscopy were enrolled in a prospective, randomized study. Patients were randomized into 2 age- and sex-matched groups; group A (46 patients) with intraperitoneal (IP) ceftazidime prior to colonoscopy and group B (47 patients) without prophylactic antibiotics...
July 5, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28698249/pd-vs-hd-in-post-economic-crisis-greece-differences-in-patient-characteristics-and-estimation-of-therapy-cost
#10
Marilena Koukou
OBJECTIVE: The aim of this study was to investigate patient characteristics and make an estimation of the cost of peritoneal dialysis (PD) and hemodialysis (HD) on Greek society during the economic crisis. METHODS: We recorded the characteristics and the total cost of dialysis treatment in 100 patients on PD and 100 on HD. Total cost included dialysis procedure, consumables, drugs, laboratory tests, food, and transportation fees (only HD) and were covered by patients' insurance...
July 11, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28695556/changing-trends-in-end-stage-renal-disease-patients-with-diabetes
#11
Yimin Lu, Christina Stamm, Dina Nobre, Menno Pruijm, Daniel Teta, Anne Cherpillod, Georges Halabi, Olivier Phan, Zina Fumeaux, Roberto Bullani, Thierry Gauthier, Claudine Mathieu, Michel Burnier, Anne Zanchi
BACKGROUND: Worldwide, diabetes has become the most common cause of end-stage renal disease (ESRD), yet Swiss data are largely lacking. METHODS: This observational study examined ESRD patients with diabetes mellitus (ESRD-DM) at end of 2009 and 2014. The prevalence and characteristics of ESRD-DM patients were collected in all dialysis facilities in the Canton of Vaud of Switzerland in 2009 and in 2014, and the 5-year mortality rate was assessed. RESULTS: A total of 107 and 140 ESRD-DM patients underwent dialysis at end of 2009 and 2014, respectively...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28680826/relationship-between-trajectories-of-serum-albumin-levels-and-technique-failure-according-to-diabetic-status-in-peritoneal-dialysis-patients-a-joint-modeling-approach
#12
Mehri Khoshhali, Iraj Kazemi, S Mohsen Hosseini, Shiva Seirafian
BACKGROUND: In peritoneal dialysis, technique failure is an important metric to be considered. This study was performed in order to identify the relationship between trajectories of serum albumin levels and peritoneal dialysis technique failure on end-stage renal disease patients according to diabetic status. Furthermore, this study was performed to reveal predictors of serum albumin and technique failure simultaneously. METHODS: This retrospective cohort study included 300 (189 non-diabetic and 111 diabetic) end-stage renal disease patients on continuous ambulatory peritoneal dialysis treated in Al-Zahra Hospital, Isfahan, Iran, from May 2005 to March 2015...
June 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/28676514/rapid-change-in-residual-renal-function-decline-is-associated-with-lower-survival-and-worse-residual-renal-function-preservation-in-peritoneal-dialysis-patients
#13
Susie L Hu, Priyanka Joshi, Mark Kaplan, Judy Lefkovitz, Andreea Poenariu, Lance D Dworkin, Dominique S Michaud
The survival advantage observed among peritoneal dialysis patients early on after dialysis initiation has been largely attributed to residual renal function (RRF) preservation due to higher baseline residual function and fewer comorbidities. We hypothesize that a rapid decline in RRF is associated with higher risk of anuria and mortality. In a retrospective cohort study of 581 subjects on peritoneal dialysis with longitudinal prevalent data, we assessed whether RRF change over time, in addition to baseline RRF, increased risk of mortality and anuria using Kaplan-Meier analysis and Cox proportional hazard analysis to control for known risk factors...
July 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28651309/the-pattern-of-choosing-dialysis-modality-and-related-mortality-outcomes-in-korea-a-national-population-based-study
#14
Hyung Jong Kim, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Hyeong-Cheon Park, Shin-Wook Kang, Kyoung Hoon Kim, Dong-Ryeol Ryu, Hyunwook Kim
BACKGROUND/AIMS: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients. METHODS: We analyzed 32,280 incident dialysis patients in Korea. Patterns in initial dialysis choice were assessed by multivariate logistic regression analyses. Multivariate Poisson regression analyses were performed to evaluate the effects of interactions between comorbidities and dialysis modality on mortality and to quantify these interactions using the synergy factor...
July 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28638613/cuff-extrusion-in-peritoneal-dialysis-single-centre-experience-with-the-cuff-shaving-procedure-in-five-patients-over-a-4-year-period
#15
Jedrzej A Debowski, Cora Wærp, Stig A Kjellevold, Sadollah Abedini
Catheter-related infections in peritoneal dialysis (PD) remain a significant complication, and some patients with recurrent exit-site (ESI) and/or tunnel infections may experience external cuff extrusion. In these cases, cuff-shaving has been described as a possible course of treatment. During a 4-year period, there were 44 patients with PD at our department; all received double-cuffed Tenckhoff catheters. Six (13%) never started on PD. Five (13%) of the 38 active PD patients experienced cuff extrusion. Causes of end-stage renal disease (ESRD) were diabetic nephropathy (n = 1), toxic nephropathy (n = 1), hypertensive nephrosclerosis (n = 1), systemic disease (n = 1) and one with unknown cause...
February 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28633134/peritoneal-water-transport-characteristics-of-diabetic-patients-undergoing-peritoneal-dialysis-a-longitudinal-study
#16
Ana Fernandes, Roi Ribera-Sanchez, Ana Rodríguez-Carmona, Antía López-Iglesias, Natacha Leite-Costa, Miguel Pérez Fontán
BACKGROUND: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal water transport in this population have not been studied sufficiently. METHOD: Following a prospective, single-center design we made cross-sectional and longitudinal comparisons of peritoneal water transport in 2 relatively large samples of diabetic and nondiabetic PD patients...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28614819/osteoprotegerin-is-the-strongest-predictor-for-progression-of-arterial-calcification-in-peritoneal-dialysis-patients
#17
Marcela Avila, Carmen Mora, María Del Carmen Prado, Miriam Zavala, Ramón Paniagua
BACKGROUND: Arterial calcification (AC) is frequent in patients with end stage renal disease and is also considered a risk factor for later morbidity and mortality. However, long-term factors associated with the process are not well known. We analyzed the trends over time of biomarkers related with development and progression of AC in incident patients on peritoneal dialysis (PD). METHODS: We performed a prospective study with 186 patients on PD followed up for 1 year...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28583215/waist-circumference-as-a-predictor-of-mortality-in-peritoneal-dialysis-patients-a-follow-up-study-of-48-months
#18
Ana Catarina M Castro, Ana Paula Bazanelli, Fabiana B Nerbass, Lilian Cuppari, Maria A Kamimura
Body-fat gain is a common finding among peritoneal dialysis (PD) patients, and the accumulation of adipose tissue occurs predominantly in the abdominal area. Waist circumference (WC) is a reliable marker of abdominal obesity and its association with worse outcomes has been demonstrated in non-dialysis and haemodialysis patients. We aimed at investigating whether WC measurements as well as the changes over time in WC were able to predict mortality in PD patients. This prospective study included 109 patients undergoing PD (57 % male, age 52 (sd 16) years, 32 % diabetics, 48 % BMI≥25 kg/m2)...
May 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28583107/the-impact-of-peritoneal-dialysis-related-peritonitis-on-mortality-in-peritoneal-dialysis-patients
#19
Hongjian Ye, Qian Zhou, Li Fan, Qunying Guo, Haiping Mao, Fengxian Huang, Xueqing Yu, Xiao Yang
BACKGROUND: Results concerning the association between peritoneal dialysis-related peritonitis and mortality in peritoneal dialysis patients are inconclusive, with one potential reason being that the time-dependent effect of peritonitis has rarely been considered in previous studies. This study aimed to evaluate whether peritonitis has a negative impact on mortality in a large cohort of peritoneal dialysis patients. We also assessed the changing impact of peritonitis on patient mortality with respect to duration of follow-up...
June 5, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28564640/impact-of-diabetes-on-extracellular-volume-status-in-patients-initiating-peritoneal-dialysis
#20
Aniema Udo, Catriona Goodlad, Andrew Davenport
BACKGROUND: Recent reports have highlighted that diabetic patients with kidney failure are at increased risk of technique failure and transfer to haemodialysis within 90 days of initiating peritoneal dialysis (PD). We wished to determine whether there were differences between diabetic and non-diabetic patients within the first 3 months of starting PD. METHODS: We reviewed results of corresponding bioimpedance and the 1st test of peritoneal membrane function (PET) in consecutive patients, 6-10 weeks after initiating PD electively...
2017: American Journal of Nephrology
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