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https://www.readbyqxmd.com/read/29908484/ethnic-differences-in-the-diagnosis-of-schizophrenia-and-mood-disorders-during-admission-to-an-academic-safety-net-psychiatric-hospital
#1
Jane E Hamilton, Angela M Heads, Thomas D Meyer, Pratikkumar V Desai, Olaoluwa O Okusaga, Raymond Y Cho
U.S. Hispanics, now the single largest minority group in the country, face unique mental health disparities. The current study utilizes Andersen's Behavioral Model of Health Service Use to examine ethnic disparities in receiving a schizophrenia or mood disorder diagnosis at psychiatric hospital admission. Our retrospective cohort study examined electronic health record data at an academic safety-net psychiatric hospital for adult patients (n = 5571) admitted between 2010 and 2013. Logistic regression with block-wise entry of predisposing, enabling and need variables was used to examine ethnic disparities in receiving a schizophrenia diagnosis at admission...
May 30, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29908476/abnormal-early-dynamic-individual-patterns-of-functional-networks-in-low-gamma-band-for-depression-recognition
#2
Kun Bi, Mahammad Ridwan Chattun, Xiaoxue Liu, Qiang Wang, Shui Tian, Siqi Zhang, Qing Lu, Zhijian Yao
BACKGROUND: The functional networks are associated with emotional processing in depression. The mapping of dynamic spatio-temporal brain networks is used to explore individual performance during early negative emotional processing. However, the dysfunctions of functional networks in low gamma band and their discriminative potentialities during early period of emotional face processing remain to be explored. METHODS: Functional brain networks were constructed from the MEG recordings of 54 depressed patients and 54 controls in low gamma band (30-48 Hz)...
June 13, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29908433/a-retrospective-analysis-of-the-association-between-providing-nicotine-replacement-therapy-at-admission-and-motivation-to-quit-and-nicotine-withdrawal-symptoms-during-an-inpatient-psychiatric-hospitalization
#3
Chizimuzo T C Okoli, Yazan D Al-Mrayat, Charles I Shelton, Milan Khara
BACKGROUND: Psychiatric patients have high tobacco use prevalence, dependence, and withdrawal severity. A tobacco-free psychiatric hospitalization necessitates the management of nicotine withdrawal (NW) for tobacco using patients. NW management often requires the provision of approved nicotine replacement therapy (NRT) to patients, which may also motivate tobacco users towards cessation. However, few studies have examined the associations between providing NRT, motivation to quit, and NW among psychiatric patients...
June 7, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29908369/repolarization-heterogeneity-in-patients-with-cardiac-resynchronization-therapy-and-its-relation-to-ventricular-tachyarrhythmias
#4
Marta Cvijić, Bor Antolič, Luka Klemen, Igor Zupan
BACKGROUND: s: Cardiac resynchronization therapy (CRT) has shown to induce left ventricular reverse remodelling, but little is known about its influence on ventricular repolarization. OBJECTIVE: The aim of our study was to evaluate changes of ventricular repolarization of native conduction after CRT and its relation to ventricular tachycardia (VT) and ventricular fibrillation (VF) during long-term follow-up. METHODS: We prospectively included 64 patients with heart failure treated with CRT...
June 13, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29908325/dopamine-d2-receptor-activation-potently-inhibits-striatal-glutamatergic-transmission-in-a-g2019s-lrrk2-genetic-model-of-parkinson-s-disease
#5
Alessandro Tozzi, Valentina Durante, Guendalina Bastioli, Petra Mazzocchetti, Salvatore Novello, Alessandro Mechelli, Michele Morari, Cinzia Costa, Andrea Mancini, Massimiliano Di Filippo, Paolo Calabresi
Among genetic abnormalities identified in Parkinson's disease (PD), mutations of the leucine-rich repeat kinase2 (LRRK2) gene, such as the G2019S missense mutation linked to enhanced kinase activity, are the most common. While the complex role of LRRK2 has not been fully elucidated, evidence that mutated kinase activity affects synaptic transmission has been reported. Thus, our aim was to explore possible early alterations of neurotransmission produced by the G2019S LRRK2 mutation in PD. We performed electrophysiological patch-clamp recordings of striatal spiny projection neurons (SPNs) in the G2019S-Lrrk2 knock-in (KI) mouse model of PD, in D1994S kinase-dead (KD), Lrrk2 knock-out (KO) and wild-type (WT) mice...
June 13, 2018: Neurobiology of Disease
https://www.readbyqxmd.com/read/29908292/the-correlations-between-electroencephalogram-frequency-components-and-restoration-of-stable-breathing-from-respiratory-events-in-sleep-apnea-hypopnea-syndrome
#6
Shaoxiong Huang, Tingting Wang, Xiangmin Zhang, Chen-Wen Yen, Jiuxing Liang, Lingzi Zeng, Yuxi Luo
The purpose of this study was to explore the ways in which the Electroencephalogram (EEG) and oxygen saturation (SpO2 ) are involved in the progressive respiratory restoration process in patients with sleep apnea hypopnea syndrome (SAHS). Twenty-five SAHS patients were enrolled in the analysis. The respiratory events scored from polysomnography (PSG) recordings were divided into two groups as follows: the events followed by secondary events (SREs), which failed to recover stable breathing and those that spontaneously restored stable ventilation (N-SREs)...
June 13, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29908175/young-patients-with-sporadic-colorectal-adenomas-current-endoscopic-surveillance-practices-and-outcomes
#7
Jae Myung Cha, Danielle La Selva, Richard A Kozarek, Michael Gluck, Andrew Ross, Otto S Lin
BACKGROUND AND AIMS: For young individuals (<40) without strong family histories that would put them at risk for genetic colorectal cancer syndromes, it is unclear if national Multi-Society Task Force surveillance recommendations apply or if endoscopists follow these guideline recommendations when such patients are incidentally found to have adenoma(s) on colonoscopy. METHODS: We reviewed records on young (<40-year-old) patients, with either no family history or only a "moderate" family history (one first-degree family member with colorectal cancer at age ≥50), who were found to have neoplastic polyp(s) on their index colonoscopy...
June 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29908131/low-body-mass-index-is-a-risk-factor-for-hyperkalaemia-associated-with-angiotensin-converting-enzyme-inhibitors-and-angiotensin-ii-receptor-blockers-treatments
#8
T Hirai, R Yamaga, A Fujita, T Itoh
WHAT IS KNOWN AND OBJECTIVE: Angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) represent the cornerstones of hypertension and congestive heart failure treatment. Risk factors for hyperkalaemia associated with ACEI and ARB are chronic kidney disease and concomitant medications which increase serum potassium level. Body mass index (BMI) also affects pharmacokinetics of ACEI and ARB and potassium disposition. We evaluated the relationship between BMI and hyperkalaemia associated with ACEI and ARB treatments...
June 16, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29908088/influence-of-suturing-technique-on-wound-healing-and-patient-morbidity-after-connective-tissue-harvesting-a-randomized-clinical-trial
#9
G N E Maino, C Valles, A Santos, A Pascual, C Esquinas, J Nart
OBJECTIVES: The aims of this randomized clinical trial were to investigate the influence of the suturing technique and the thickness of the pre- and postoperative palatal and flap mucosa on the early healing of the palate after harvesting a connective tissue graft. Furthermore, patient pain perception was evaluated. MATERIAL AND METHODS: A subepithelial connective tissue graft was obtained from the palate with a single horizontal incision technique. Patients were randomly assigned to continuous interlocking suture group or criss-cross suture group...
June 16, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29907928/trends-in-the-incidence-of-retinopathy-of-prematurity-over-a-10-year-period
#10
Prudence P C Chow, Wilson W K Yip, Mary Ho, Julie Y C Lok, Henry H W Lau, Alvin L Young
AIM: To describe and evaluate the trends in the incidence of retinopathy of prematurity over a 10-year period in a tertiary hospital in Hong Kong. METHODS: A retrospective review was performed on all preterm infants screened and/or treated for retinopathy of prematurity from January 2006 to December 2015 at Prince of Wales Hospital, Hong Kong. Preterm infants with incomplete records or transferred-in from other hospitals/region solely for treatment of ROP were excluded...
June 16, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29907914/asylum-seekers-in-a-time-of-record-forced-global-displacement-the-role-of-physicians
#11
Katherine C McKenzie, Jon Bauer, P Preston Reynolds
In 2016, over 65 million individuals were displaced from their homes due to human rights abuses, and 262,000 people applied for asylum in the USA. Individuals who have experienced persecution are present in many primary and specialty clinics. A medical forensic evaluation can increase the likelihood of a successful asylum case. This paper reviews the legal framework for asylum and the contribution forensic evaluations can make to this vulnerable population. Physicians without asylum expertise can help these patients by recognizing their legal right to residential protection and referring them to lawyers and physicians with expert skills...
June 15, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29907885/recognition-and-control-of-hypertension-diabetes-and-dyslipidemia-in-patients-with-rheumatoid-arthritis
#12
Luísa Lima Castro, Cristina Costa Duarte Lanna, Mariana Pimenta Rocha, Antônio Luiz Pinho Ribeiro, Rosa Weiss Telles
Absolute cardiovascular risk of an individual with rheumatoid arthritis (RA) is greater when compared to the general population, and several factors have proven to be important for the development of coronary artery disease (CAD) in these patients, including factors related to the underlying disease, such as the systemic inflammatory response, drugs used in its treatment, and a higher prevalence of traditional risk factors for CAD. Our aim is to describe the recognition and control frequencies of systemic arterial hypertension (SAH), dyslipidemia, and diabetes mellitus (DM) in RA patients...
June 15, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29907848/cerebral-blood-flow-and-serum-neuron-specific-enolase-in-early-onset-neonatal-sepsis
#13
Mohammed S El Shimy, Nehal M El-Raggal, Rania A El-Farrash, Hebatallah A Shaaban, Hanan E Mohamed, Noha M Barakat, Ahmed S Farag, Abeer K El Zohiery, Menat Allah A Shaaban, Dina H Salama
BACKGROUND AND OBJECTIVES: Sepsis leads to systemic inflammatory response with cerebral blood flow (CBF) alteration and blood-brain barrier disruption that contribute to sepsis-associated encephalopathy (SAE). We aimed to evaluate cord blood neuron-specific enolase (cNSE) and CBF in early-onset neonatal sepsis (EONS) as predictors of SAE and to define short-term neurodevelopmental outcomes among survivors. METHODS: cNSE was measured in 200 neonates with antenatal risk factors for EONS, stratified into two groups: sepsis (n = 96) and no-sepsis (n = 104)...
May 26, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29907747/predictive-modeling-of-the-progression-of-alzheimer-s-disease-with-recurrent-neural-networks
#14
Tingyan Wang, Robin G Qiu, Ming Yu
The number of service visits of Alzheimer's disease (AD) patients is different from each other and their visit time intervals are non-uniform. Although the literature has revealed many approaches in disease progression modeling, they fail to leverage these time-relevant part of patients' medical records in predicting disease's future status. This paper investigates how to predict the AD progression for a patient's next medical visit through leveraging heterogeneous medical data. Data provided by the National Alzheimer's Coordinating Center includes 5432 patients with probable AD from August 31, 2005 to May 25, 2017...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907668/longterm-outcomes-of-188-japanese-patients-with-eosinophilic-granulomatosis-with-polyangiitis
#15
Aiko Saku, Shunsuke Furuta, Masaki Hiraguri, Kei Ikeda, Yoshihisa Kobayashi, Shin-Ichiro Kagami, Kazuhiro Kurasawa, Ryutaro Matsumura, Daiki Nakagomi, Takao Sugiyama, Takeshi Umibe, Norihiko Watanabe, Hiroshi Nakajima
OBJECTIVE: Patients with eosinophilic granulomatosis with polyangiitis (EGPA) frequently experience relapses, which lead to cumulative organ damage. In this retrospective observational study, we aimed to reveal the risk factors for relapse in EGPA. METHODS: A total of 188 Japanese patients with EGPA diagnosed between 1996 and 2015 were identified from medical records in 10 hospitals. The diagnosis was based on the American College of Rheumatology 1990 criteria or Lanham's criteria...
June 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29907666/physician-s-global-assessment-in-psoriatic-arthritis-a-multicenter-grappa-study
#16
Alberto Cauli, Dafna D Gladman, Alessandro Mathieu, Ignazio Olivieri, Giovanni Porru, Paul P Tak, Claudia Sardu, Raffaele Scarpa, Antonio Marchesoni, William J Taylor, Carlo Salvarani, Joachim Kalden, Ennio Lubrano, Sueli Carneiro, Matteo Piga, Alberto Floris, Francesca Desiati, John A Flynn, Salvatore D'Angelo, Arno W R van Kuijk, Maria Grazia Catanoso, Francesco Caso, Paolo Contu, Ilona Ujfalussy, Philip S Helliwell, Philip J Mease
OBJECTIVE: Physician's global assessment (PGA) of disease activity is a major determinant of therapeutic decision making. This study assesses the reliability of the PGA, measured by means of 0-100 mm visual analog scale (VAS), and the additional use of separate VAS scales for musculoskeletal (PhysMSK) and dermatologic (PhysSk) manifestations in patients with psoriatic arthritis (PsA). METHODS: Sixteen centers from 8 countries enrolled 319 consecutive patients with PsA...
June 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29907630/clinical-features-of-paediatric-uveitis-at-a-tertiary-referral-centre-in-s%C3%A3-o-paulo-sp-brazil
#17
Fernanda Maria Silveira Souto, Bárbara Vilela Giampietro, Julia Thiemi Takiuti, Lucia Maria Arruda Campos, Carlos Eduardo Hirata, Joyce Hisae Yamamoto
AIMS: To analyse the clinical features, systemic associations, treatment and visual outcomes of uveitis in children from a referral centre in São Paulo, Brazil. METHODS: Clinical records of patients under 16 years old who attended the Uveitis Service, Hospital das Clinicas, Faculdadede Medicina, Universidade de São PauloFMUSP, between April and September 2017, were reviewed retrospectively. Patients with incomplete medical records, previous ocular trauma, or less than six6 months of follow-up were excluded...
June 15, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29907629/cataract-surgery-refractive-outcomes-representative-standards-in-a-national-health-service-setting
#18
Kerr Brogan, Charles J M Diaper, Alan P Rotchford
BACKGROUND/AIMS: To report refractive outcomes from an National Health Service (NHS) cataract surgery service and assess if results meet suggested benchmark standard. METHODS: Details of all patients undergoing cataract surgery in the Southern General and New Victoria hospitals in Glasgow, UK, between November 2006 and December 2016 were prospectively entered into an electronic database. Patients were reviewed 4 weeks postoperatively in the eye clinic and underwent refraction at their local optometrist prior to this appointment...
June 15, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29907558/resident-and-attending-physicians-perceptions-of-patient-access-to-provider-notes-comparison-of-perceptions-prior-to-pilot-implementation
#19
Deepa Rani Nandiwada, Gary S Fischer, Glenn Updike, Margaret B Conroy
BACKGROUND: As electronic health records have become a more integral part of a physician's daily life, new electronic health record tools will continue to be rolled out to trainees. Patient access to provider notes is becoming a more widespread practice because this has been shown to increase patient empowerment. OBJECTIVE: In this analysis, we compared differences between resident and attending physicians' perceptions prior to implementation of patient access to provider notes to facilitate optimal use of electronic health record features and as a potential for patient empowerment...
June 15, 2018: JMIR Medical Education
https://www.readbyqxmd.com/read/29907546/clinical-value-of-flash-glucose-monitoring-in-patients-with-type-1-diabetes-treated-with-continuous-subcutaneous-insulin-infusion
#20
Jesus Moreno-Fernandez, Marcos Pazos-Couselo, Maria González-Rodriguez, Pedro Rozas, Manuel Delgado, Miguel Aguirre, Jose Manuel Garcia-Lopez
AIM: To analyze the clinical impact of the Flash glucose monitoring system in patients with type 1 diabetes mellitus (T1DM) treated with continuous subcutaneous insulin infusion (CSII). METHODS: A 24-week retrospective cohort study in CSII-treated T1DM patients exposed (1:1) to the Flash glucose monitoring system vs. self-monitoring of capillary blood glucose (SMBG). The primary outcome was the difference in hemoglobin A1c (HbA1c) levels between both groups at the end of the study...
June 12, 2018: Endocrinología, Diabetes y Nutrición
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