keyword
MENU ▼
Read by QxMD icon Read
search

Allostasis

keyword
https://www.readbyqxmd.com/read/29886495/early-life-stress-from-neuroendocrine-mechanisms-to-stress-related-disorders
#1
Panagiota Pervanidou, George P Chrousos
Stress exposure is highly prevalent in the general population; however, the experience of stress during vulnerable periods of development has substantial and permanent effects on brain structure and function and physical health in adulthood. Stress, the state of threatened homeostasis, is generally associated with a time-limited activation of the stress system, i.e., the hypothalamic-pituitary-adrenal axis and the arousal/sympathetic nervous system, tailored to the stressful stimulus also known as the stressor...
June 8, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29721768/altered-resting-state-functional-connectivity-of-the-cognitive-control-network-in-fibromyalgia-and-the-modulation-effect-of-mind-body-intervention
#2
Jian Kong, Emily Wolcott, Zengjian Wang, Kristen Jorgenson, William F Harvey, Jing Tao, Ramel Rones, Chenchen Wang
This study examines altered resting state functional connectivity (rsFC) of the cognitive control network (CCN) in fibromyalgia patients as compared to healthy controls, as well as how an effective mind-body intervention, Tai Chi, can modulate the altered rsFC of the CCN. Patients with fibromyalgia and matched healthy subjects were recruited in this study. Fibromyalgia patients were scanned 12 weeks before and after intervention. The bilateral dorsolateral prefrontal cortex (DLPFC) was used as a seed to explore the rsFC of the CCN...
May 2, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29672605/concentration-related-metabolic-rate-and-behavioral-thermoregulatory-adaptations-to-serial-administrations-of-nitrous-oxide-in-rats
#3
Karl J Kaiyala, Douglas S Ramsay
BACKGROUND: Initial administration of ≥60% nitrous oxide (N2O) to rats evokes hypothermia, but after repeated administrations the gas instead evokes hyperthermia. This sign reversal is driven mainly by increased heat production. To determine whether rats will behaviorally oppose or assist the development of hyperthermia, we previously performed thermal gradient testing. Inhalation of N2O at ≥60% causes rats to select cooler ambient temperatures both during initial administrations and during subsequent administrations in which the hyperthermic state exists...
2018: PloS One
https://www.readbyqxmd.com/read/29652832/sympathetic-nerve-hyperactivity-in-the-spleen-causal-for-nonpathogenic-driven-chronic-immune-mediated-inflammatory-diseases-imids
#4
REVIEW
Denise L Bellinger, Dianne Lorton
Immune-Mediated Inflammatory Diseases (IMIDs) is a descriptive term coined for an eclectic group of diseases or conditions that share common inflammatory pathways, and for which there is no definitive etiology. IMIDs affect the elderly most severely, with many older individuals having two or more IMIDs. These diseases include, but are not limited to, type-1 diabetes, obesity, hypertension, chronic pulmonary disease, coronary heart disease, inflammatory bowel disease, and autoimmunity, such as rheumatoid arthritis (RA), Sjőgren's syndrome, systemic lupus erythematosus, psoriasis, psoriatic arthritis, and multiple sclerosis...
April 13, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29617633/reducing-racial-ethnic-tobacco-cessation-disparities-via-cognitive-behavioral-therapy-design-of-a-dualsite-randomized-controlled-trial
#5
Monica Webb Hooper, David J Lee, Vani N Simmons, Karen O Brandon, Michael H Antoni, Marina Unrod, Taghrid Asfar, John B Correa, Tulay Koru-Sengul, Thomas H Brandon
Racial/ethnic disparities in tobacco cessation are such that U.S. minorities have greater difficulty quitting compared to White non-Hispanics. Group differences in distress (i.e., perceived stress and depressive symptoms) may contribute to cessation disparities. The allostasis model of health suggests that the toll of chronic stress experienced by racial/ethnic minorities may lead to dysregulation of the physiological stress system and drug use. Previous research suggests that group cognitive behavioral therapy (CBT) for tobacco cessation addresses distress as a modifiable mechanism and has the potential to reduce/eliminate disparities...
May 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29607505/brain-heart-interaction-in-perseverative-cognition
#6
Cristina Ottaviani
The move from the concept of homeostasis to that of allostasis has led reactivity stress research to widen the object of its investigation: from the brief physiological response that occurs when one is facing a stressor to what happens when one is anticipating or recovering from a stressor. A paradigmatic example is represented by perseverative cognition, during which human beings react "as if" they were constantly facing a concrete stressor. The core idea behind this review is that the cognitive inflexibility that characterizes perseverative cognition is reflected in both our body (by increased autonomic nervous system rigidity assessed by heart rate variability; HRV) and our brain (by reduced prefrontal-amygdala functional connectivity)...
April 1, 2018: Psychophysiology
https://www.readbyqxmd.com/read/29559024/early-adversity-and-internalizing-symptoms-in-adolescence-mediation-by-individual-differences-in-latent-trait-cortisol
#7
Catherine B Stroud, Frances R Chen, Leah D Doane, Douglas A Granger
Research suggests that early adversity places individuals at risk for psychopathology across the life span. Guided by concepts of allostasis and allostatic load, the present study examined whether early adversity contributes to the development of subsequent internalizing symptoms through its association with traitlike individual differences in hypothalamic-pituitary-adrenal axis regulation. Early adolescent girls (n = 113; M age = 12.30 years) provided saliva samples at waking, 30 min postwaking, and bedtime over 3 days (later assayed for cortisol)...
March 21, 2018: Development and Psychopathology
https://www.readbyqxmd.com/read/29494257/stress-telomeres-and-psychopathology-toward-a-deeper-understanding-of-a-triad-of-early-aging
#8
Elissa S Epel, Aric A Prather
Telomeres play an important part in aging and show relationships to lifetime adversity, particularly childhood adversity. Meta-analyses demonstrate reliable associations between psychopathology (primarily depression) and shorter telomere length, but the nature of this relationship has not been fully understood. Here, we review and evaluate the evidence for impaired telomere biology as a consequence of psychopathology or as a contributing factor, and the important mediating roles of chronic psychological stress and impaired allostasis...
May 7, 2018: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29459378/role-of-allostatic-load-and-health-behaviours-in-explaining-socioeconomic-disparities-in-mortality-a-structural-equation-modelling-approach
#9
Gyu Ri Kim, Sun Ha Jee, Hynek Pikhart
BACKGROUND: The relationship between socioeconomic status and mortality has been well established; however, the extent to which biological factors mediate this relationship is less clear, and empirical evidence from non-Western settings is limited. Allostasis, a cumulative measure of physiological dysregulation, has been proposed as the underlying mechanism linking socioeconomic status to adverse health outcomes. The current study aimed to ascertain the contribution of allostatic load (AL) and health behaviours to socioeconomic inequalities in mortality among Korean adults...
June 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29445338/synaptic-homeostasis-and-allostasis-in-the-dentate-gyrus-caused-by-inflammatory-and-neuropathic-pain-conditions
#10
Rui-Rui Wang, Yan Wang, Su-Min Guan, Zhen Li, Saurabh Kokane, Fa-Le Cao, Wei Sun, Chun-Li Li, Ting He, Yan Yang, Qing Lin, Jun Chen
It has been generally accepted that pain can cause imbalance between excitation and inhibition (homeostasis) at the synaptic level. However, it remains poorly understood how this imbalance (allostasis) develops in the CNS under different pain conditions. Here, we analyzed the changes in both excitatory and inhibitory synaptic transmission and modulation of the dentate gyrus (DG) under two pain conditions with different etiology and duration. First, it was revealed that the functions of the input-output (I/O) curves for evoked excitatory postsynaptic currents (eEPSCs) following the perforant path (PP) stimulation were gained under both acute inflammatory and chronic neuropathic pain conditions relative to the controls...
2018: Frontiers in Synaptic Neuroscience
https://www.readbyqxmd.com/read/29432781/pleiotropy-the-physiologic-basis-for-biologic-fields
#11
REVIEW
John S Torday
Biologic organisms act like fields. Hypothetically, pleiotropy results from the systematic re-purposing of genes over the course of the evolutionary history of the organism as pre-adaptations or exaptations. Mechanistically, pleiotropic genes are selected for during the process of evolution with reference to the First Principles of Physiology (FPP). Under stress conditions, pleiotropic genes will act as a functional network to cohesively maintain allostasis. There are strong homologies between Quantum Mechanics and the FPP...
August 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/29382627/migration-influences-on-the-allostatic-load-of-children-systematic-review-protocol
#12
Ivan Neil Gomez, Cynthia Yy Lai, Trevor Wk Yung, Chetwyn Ch Chan, Hector Wh Tsang
BACKGROUND: Migration is a worldwide phenomenon in recent times. Recently, documented studies suggest that the change in environments involved in migration may have an influence on children's allostatic load related to health and well-being. OBJECTIVE: The aim of this review is to systematically search the extant literature and critically examine the evidence on how migration affects allostatic load in children and describe the relevant methods in measuring allostatic load...
January 30, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29379966/conceptualizing-addiction-from-an-osteopathic-perspective-dopamine-homeostasis
#13
Dave Baron, Kenneth Blum, Anthony Chen, Mark Gold, Rajendra D Badgaiyan
Addiction is a public health crisis in the United States. Understanding the cause and providing effective treatment for patients-in particular, those with substance use disorders-is challenging. Research has demonstrated that addiction is not a flaw in one's moral fiber or a disease of choice; rather, it is driven by alterations in neuronal mechanisms, especially those that involve the neurotransmitter dopamine, which plays a critical role in the brain's reward pathway. Much of osteopathic philosophy is based on the concept of total body homeostasis and allostasis...
February 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29310960/cannabinoid-hyperemesis-syndrome-pathophysiology-and-treatment-in-the-emergency-department
#14
John R Richards
BACKGROUND: Cannabinoid hyperemesis syndrome (CHS) is a challenging clinical disorder. CHS patients frequently present to the emergency department and may require treatment for intractable emesis, dehydration, and electrolyte abnormalities. Thought to be a variant of cyclic vomiting syndrome, CHS has become more prevalent with increasing cannabis potency and use, as enabled by various states having legalized the recreational use of cannabis. OBJECTIVE: This aim of this review is to investigate the pathophysiology of CHS and evaluate the published literature on pharmacologic treatment in the emergency department...
March 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29130725/-eighth-jes%C3%A3%C2%BAs-culebras-lecture-critical-care-nutrition-and-hyperglycemia-a-close-relationship
#15
Alfonso Mesejo
Critically ill patients show a metabolic response to injury that affects carbohydrate metabolism, causing hyperglycemia and an increase in glycemic variability that makes the critically ill patient susceptible to infection, resulting in morbidity and mortality increase. Also, severe hypoglycemia was detected as a consequence of intensive insulin treatment that provokes deleterious effects in their clinical evolution, so a correct monitoring of plasma glucose would contribute to reduce morbidity and mortality...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28983518/evidence-for-a-large-scale-brain-system-supporting-allostasis-and-interoception-in-humans
#16
Ian R Kleckner, Jiahe Zhang, Alexandra Touroutoglou, Lorena Chanes, Chenjie Xia, W Kyle Simmons, Karen S Quigley, Bradford C Dickerson, Lisa Feldman Barrett
Large-scale intrinsic brain systems have been identified for exteroceptive senses (e.g., sight, hearing, touch). We introduce an analogous system for representing sensations from within the body, called interoception, and demonstrate its relation to regulating peripheral systems in the body, called allostasis. Employing the recently introduced Embodied Predictive Interoception Coding (EPIC) model, we used tract-tracing studies of macaque monkeys, followed by two intrinsic functional magnetic resonance imaging samples ( N = 280 and N = 270) to evaluate the existence of an intrinsic allostatic/interoceptive system in the human brain...
2017: Nature Human Behaviour
https://www.readbyqxmd.com/read/28940503/measuring-arterial-blood-pressure-in-humans-auscultatory-and-automatic-measurement-techniques-for-human-biological-field-studies
#17
Gary D James, Linda M Gerber
Human biologists have been examining arterial blood pressure since they began studying the effects of the environment and culture on the health of diverse populations. The Korotkoff auscultatory technique with a trained observer and aneroid sphygmomanometer is the method of choice for blood pressure measurement in many bioanthropological field contexts. Korotkoff sounds (the first and fifth phases) are the preferred determinants of systolic and diastolic pressure, even in infants, children, pregnant women, and the elderly...
January 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28880949/maternal-hypothalamic-pituitary-adrenal-axis-response-to-foraging-uncertainty-a-model-of-individual-vs-social-allostasis-and-the-superorganism-hypothesis
#18
Jeremy D Coplan, Nishant K Gupta, Asif Karim, Anna Rozenboym, Eric L P Smith, John G Kral, Leonard A Rosenblum
INTRODUCTION: Food insecurity is a major global contributor to developmental origins of adult disease. The allostatic load of maternal food uncertainty from variable foraging demand (VFD) activates corticotropin-releasing factor (CRF) without eliciting hypothalamic-pituitary-adrenal (HPA) activation measured on a group level. Individual homeostatic adaptations of the HPA axis may subserve second-order homeostasis, a process we provisionally term "social allostasis." We postulate that maternal food insecurity induces a "superorganism" state through coordination of individual HPA axis response...
2017: PloS One
https://www.readbyqxmd.com/read/28868531/a-control-theory-model-of-smoking
#19
Georgiy Bobashev, John Holloway, Eric Solano, Boris Gutkin
We present a heuristic control theory model that describes smoking under restricted and unrestricted access to cigarettes. The model is based on the allostasis theory and uses a formal representation of a multiscale opponent process. The model simulates smoking behavior of an individual and produces both short-term ("loading up" after not smoking for a while) and long-term smoking patterns (e.g., gradual transition from a few cigarettes to one pack a day). By introducing a formal representation of withdrawal- and craving-like processes, the model produces gradual increases over time in withdrawal- and craving-like signals associated with abstinence and shows that after 3 months of abstinence, craving disappears...
June 2017: Methods Report
https://www.readbyqxmd.com/read/28862266/genomic-and-epigenomic-mechanisms-of-glucocorticoids-in-the-brain
#20
REVIEW
Jason D Gray, Joshua F Kogan, Jordan Marrocco, Bruce S McEwen
Following the discovery of glucocorticoid receptors in the hippocampus and other brain regions, research has focused on understanding the effects of glucocorticoids in the brain and their role in regulating emotion and cognition. Glucocorticoids are essential for adaptation to stressors (allostasis) and in maladaptation resulting from allostatic load and overload. Allostatic overload, which can occur during chronic stress, can reshape the hypothalamic-pituitary-adrenal axis through epigenetic modification of genes in the hippocampus, hypothalamus and other stress-responsive brain regions...
November 2017: Nature Reviews. Endocrinology
keyword
keyword
8147
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"