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https://www.readbyqxmd.com/read/29784460/review-of-real-time-3-dimensional-image-guided-radiation-therapy-on-standard-equipped-cancer-radiation-therapy-systems-are-we-at-the-tipping-point-for-the-era-of-real-time-radiation-therapy
#1
Paul J Keall, Doan Trang Nguyen, Ricky O'Brien, Pengpeng Zhang, Laura Happersett, Jenny Bertholet, Per R Poulsen
PURPOSE: To review real-time 3-dimensional (3D) image guided radiation therapy (IGRT) on standard-equipped cancer radiation therapy systems, focusing on clinically implemented solutions. METHODS AND MATERIALS: Three groups in 3 continents have clinically implemented novel real-time 3D IGRT solutions on standard-equipped linear accelerators. These technologies encompass kilovoltage, combined megavoltage-kilovoltage, and combined kilovoltage-optical imaging. The cancer sites treated span pelvic and abdominal tumors for which respiratory motion is present...
April 14, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29783902/optimal-plate-fixation-of-distal-femoral-fractures-in-the-presence-of-a-well-fixed-cemented-hip-arthroplasty-femoral-stem
#2
Josh Kempthorne, David C Kieser, Cameron G Walker
INTRODUCTION: The requirement for lateral plate fixation in the presence of a hip arthroplasty stem is increasing, yet the optimal plate construct necessary to reduce inter-prosthetic strain and prevent subsequent fractures is unknown. Therefore, the purpose of this study was to determine the optimal position of a lateral femoral plate in relation to a femoral stem. METHODS: We used 4th Generation Composite Sawbones® , a collarless polished cemented femoral stem and a broad Peri-loc™ plate with varying overlap of the stem...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29783889/the-external-obturator-footprint-as-a-landmark-in-total-hip-arthroplasty-through-a-direct-anterior-approach-a-ct-based-analysis
#3
Hannes A Rüdiger, Benjamin Fritz, Franco M Impellizzeri, Michael Leunig, Christian W Pfirrmann, Reto Sutter
BACKGROUND: Anatomical landmarks for templating of total hip arthroplasty (THA) that are visible both during surgery and on radiographs are rare. If surgery is performed through a direct anterior approach the external obturator tendon (EO) is consistently visible. To use this point as a reference the exact position and dimensions of the footprint need to be known. AIM: To determine the location and dimension of the EO footprint on pelvic radiographs by correlating the EO anatomy in CT scans with conventional radiographs...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29776126/early-warning-signals-of-critical-transition-effect-of-extrinsic-noise
#4
Shanshan Qin, Chao Tang
Complex dynamical systems often have tipping points and exhibit catastrophic regime shift. Despite the notorious difficulty of predicting such transitions, accumulating studies have suggested the existence of generic early-warning signals (EWSs) preceding upcoming transitions. However, previous theories and models were based on the effect of the intrinsic noise (IN) when a system is approaching a critical point, and did not consider the pervasive environmental fluctuations or the extrinsic noise (EN). Here, we extend previous theory to investigate how the interplay of EN and IN affects EWSs...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775855/dual-core-all-fiber-integrated-immunosensor-for-detection-of-protein-antigens
#5
Karol Wysokiński, Dawid Budnicki, Janusz Fidelus, Łukasz Szostkiewicz, Łukasz Ostrowski, Micha Murawski, Marcin Staniszewski, Magdalena Staniszewska, Marek Napierała, Tomasz Nasiłowski
An optical fiber interferometric microprobe for detection of specific proteins is presented in this paper. The microprobe is an all-fiber device, which is based on Michelson interferometer configuration, which allows for detection of protein antigens in an analyzed solution thanks to antibodies immobilized on the sensor surface. The interferometer is made of dual core fiber and has a precisely formed arm length difference, achieved by splicing a fragment of polarization maintaining fiber to one of the cores...
May 9, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29775377/rate-and-state-friction-relation-for-nanoscale-contacts-thermally-activated-prandtl-tomlinson-model-with-chemical-aging
#6
Kaiwen Tian, David L Goldsby, Robert W Carpick
Rate and state friction (RSF) laws are widely used empirical relationships that describe macroscale to microscale frictional behavior. They entail a linear combination of the direct effect (the increase of friction with sliding velocity due to the reduced influence of thermal excitations) and the evolution effect (the change in friction with changes in contact "state," such as the real contact area or the degree of interfacial chemical bonds). Recent atomic force microscope (AFM) experiments and simulations found that nanoscale single-asperity amorphous silica-silica contacts exhibit logarithmic aging (increasing friction with time) over several decades of contact time, due to the formation of interfacial chemical bonds...
May 4, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29774957/progress-and-challenges-in-consolidating-the-management-of-amazonian-protected-areas-and-indigenous-territories
#7
Raymond E Gullison, Jared Hardner
Achieving the effective management of all existing protected areas and indigenous territories in the Amazon Biome may be needed to avoid a deforestation "tipping point" beyond which regional climatic feedbacks and global climate change interact to catalyze irreversible drying and savannization of large portions of the biome. However, the time and money required to consolidate the effective management of all types of protected sites in the Amazon is still poorly understood. At present, protected areas and indigenous territories cover 45...
May 18, 2018: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29774532/the-fetus-at-the-tipping-point-modifying-the-outcome-of-fetal-asphyxia
#8
Simerdeep K Dhillon, Christopher A Lear, Robert Galinsky, Guido Wassink, Joanne O Davidson, Sandra Juul, Nicola J Robertson, Alistair J Gunn, Laura Bennet
Brain injury around birth is associated with nearly half of all cases of cerebral palsy. Although brain injury is multifactorial, particularly after preterm birth, acute hypoxia-ischaemia is a major contributor to injury. It is now well established that the severity of injury after HI is determined by a dynamic balance between injurious and protective processes. In addition, mothers who are at risk of premature delivery have high rates of diabetes and antepartum infection/inflammation and are almost universally given treatments such as antenatal glucocorticoids and magnesium sulphate to reduce the risk of death and complications after preterm birth...
May 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29771042/-alarming-system-in-real-time-and-high-quality-display-using-volumerendering-for-otologic-surgical-navigation-a-preclinical-study
#9
W Y Zhang, G D Feng, S Q Chen, Q W Huang, Z Q Gao
Objective: The aim of this study is to design and develop a novel navigation framework that alarms the surgeon with sound during drilling and dynamically renders the high quality medical image data. Method: The accuracy of the proposed system were measured with a skull model using paired point registration and the target registration error (TRE) was computed. We segmented the accurate structure of target and compute the minimum distance between the drill tip and the target. Once the drill tip approached the target structures, the system would alarm the surgeon...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29769332/identification-of-plant-virus-receptor-candidates-in-the-stylets-of-their-aphid-vectors
#10
Craig G Webster, Elodie Pichon, Manuella van Munster, Baptiste Monsion, Maëlle Deshoux, Daniel Gargani, Federica Calevro, Jaime Jimenez, Aranzazu Moreno, Björn Krenz, Jeremy R Thompson, Keith L Perry, Alberto Fereres, Stéphane Blanc, Marilyne Uzest
Plant viruses transmitted by insects cause tremendous losses in most important crops around the world. The identification of receptors of plant viruses within their insect vectors is a key challenge to understanding the mechanisms of transmission, and offers an avenue for future alternative control strategies to limit viral spread. We here report the identification of two cuticular proteins within aphid mouthparts, and we provide experimental support for the role of one of them in the transmission of a non-circulative virus...
May 16, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29768732/the-effect-of-light-intensity-on-image-quality-in-endoscopic-ear-surgery
#11
Rhona McCallum, John McColl, Arunachalam Iyer
OBJECTIVES: Endoscopic ear surgery is a rapidly developing field with many advantages. But endoscopes can reach temperatures of over 110 C at the tip, raising safety concerns. Reducing the intensity of the light source reduces temperatures produced. However, quality of images at lower light intensities has not yet been studied. We set out to study the effect of light intensity on image quality in EES. DESIGN: Prospective study of patients undergoing EES from April to October 2016...
May 16, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29768693/coastal-ecosystems-on-a-tipping-point-global-warming-and-parasitism-combine-to-alter-community-structure-and-function
#12
Kim N Mouritsen, Mikkel M Sørensen, Robert Poulin, Brian L Fredensborg
Mounting evidence suggests that the transmission of certain parasites is facilitated by increasing temperatures, causing their host population to decline. However, no study has yet addressed how temperature and parasitism may combine to shape the functional structure of a whole host community in the face of global warming. Here, we apply an outdoor mesocosm approach supported by field surveys to elucidate this question in a diverse intertidal community of amphipods infected by the pathogenic microphallid trematode, Maritrema novaezealandensis...
May 16, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29764283/minimally-invasive-thread-trigger-digit-release-a-preliminary-report-on-34-digits-of-the-adult-hands
#13
Danqing Guo, Logan McCool, Alexander Senk, Brionn Tonkin, Joseph Guo, Rachel M Lytie, Danzhu Guo
The trigger finger release was performed in 34 digits (11 thumbs and 23 fingers) of 24 patients through the thread transecting technique with the tip-to-tip approach, in which a 22-gauge needle inserts into a 18-gauge needle when both needles are inside the hand, guiding the 22-gauge needle to exit the hand at the same access point of 18-gauge needle. We prospectively evaluated the effectiveness and functional recovery of these patients. In all 34 digits, triggering and locking were resolved, and complete extension and flexion occurred immediately following the release...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29764179/was-the-5th-international-public-health-palliative-care-conference-2017-canada-s-tipping-point-a-meeting-report
#14
Denise Marshall, Kathy Kortes-Miller
No abstract text is available yet for this article.
April 2018: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/29761208/location-of-a-grasped-object-s-effector-influences-perception-of-the-length-of-that-object-via-dynamic-touch
#15
Madhur Mangalam, James D Conners, Dorothy M Fragaszy, Karl M Newell
Perception of properties of a grasped object via dynamic touch (wielding) contributes to dexterity in tool use (e.g., using a hammer, screwdriver) and sports (e.g., hockey, tennis). These activities differ from simple object manipulation in that they involve making contact with an intended target. In the present study, we examined whether and how making (percussive) contact with a target influences perception of the length of a grasped object via dynamic touch. Making contact with a target by the tip resulted in a more accurate perception of the length than simple wielding...
May 14, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29760852/altered-mental-status-current-evidence-based-recommendations-for-prehospital-care
#16
REVIEW
Ashley Sanello, Marianne Gausche-Hill, William Mulkerin, Karl A Sporer, John F Brown, Kristi L Koenig, Eric M Rudnick, Angelo A Salvucci, Gregory H Gilbert
Introduction: In the United States emergency medical services (EMS) protocols vary widely across jurisdictions. We sought to develop evidence-based recommendations for the prehospital evaluation and treatment of a patient with an acute change in mental status and to compare these recommendations against the current protocols used by the 33 EMS agencies in the State of California. Methods: We performed a literature review of the current evidence in the prehospital treatment of a patient with altered mental status (AMS) and augmented this review with guidelines from various national and international societies to create our evidence-based recommendations...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29759657/no-radiographic-safe-margin-found-in-the-easy-ij-internal-jugular-vein-procedure
#17
Ryan N McCarter, Siamak Moayedi, Michael D Witting
BACKGROUND: The Easy IJ procedure involves placement of a 4.8-cm intravenous catheter into the internal jugular (IJ) vein using ultrasound guidance. It is not known whether this needle length has the potential to cause a pneumothorax. OBJECTIVE: The objective of this study was to determine if a radiographic "safe margin" exists. We hypothesized that an average margin of ≥2 cm would exist between the catheter tip and the pleura. METHODS: Operators used a central approach to the IJ vein...
May 11, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29757468/treatment-of-class-iii-multiple-gingival-recessions-prognostic-factors-for-achieving-a-complete-root-coverage
#18
Sofia Aroca, Antoine Barbieri, Marco Clementini, Franck Renouard, Massimo de Sanctis
BACKGROUND: This report is intended to present a supplemental analysis of data from a prior report (Aroca 2010) to investigate factors associated with a complete root coverage at 1 year. The purpose of the prior report was to investigate at 1 year the adjunction effect of EMD for the treatment of Miller's class III recession defects using a coronally advanced modified tunnel/CTG technique with (test group) or without (control group). The purpose of this report is to investigate additional factors associated with root coverage in the same data set...
May 14, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29756018/a-structured-light-laser-probe-for-gastrointestinal-polyp-size-measurement-a-preliminary-comparative-study
#19
Marco Visentini-Scarzanella, Hiroshi Kawasaki, Ryo Furukawa, Marco Augusto Bonino, Simone Arolfo, Giacomo Lo Secco, Alberto Arezzo, Arianna Menciassi, Paolo Dario, Gastone Ciuti
Background and study aims:  Polyp size measurement is an important diagnostic step during gastrointestinal endoscopy, and is mainly performed by visual inspection. However, lack of depth perception and objective reference points are acknowledged factors contributing to measurement errors in polyp size. In this paper, we describe the proof-of-concept of a polyp measurement device based on structured light technology for future endoscopes. Patients and methods:  Measurement accuracy, time, user confidence, and satisfaction were evaluated for polyp size assessment by (a) visual inspection, (b) open biopsy forceps of known size, (c) ruled snare, and (d) structured light probe, for a total of 392 independent polyp measurements in ex vivo porcine stomachs...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29753476/technical-note-the-development-of-a-methodology-for-ruminal-and-colon-tissue-biopsying-of-young-holstein-dairy-calves
#20
J K van Niekerk, M Middeldorp, M A Steele
The objectives of this study were to develop a methodology for biopsying the rumen and colon of young dairy calves and to collect suitable quality tissue samples for microscopic and gene expression analysis. Six Holstein dairy bull calves (45.0 ± 1.5 kg birth weight) were ruminally cannulated during the second week of life and weaned at the end of wk 6. Ruminal and colon tissue samples were collected at the end of wk 5, 6, 7, 8, and 12. Calves were not sedated but were restrained in a chute for sampling. The endoscope (100 cm length, 9...
May 9, 2018: Journal of Dairy Science
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