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https://www.readbyqxmd.com/read/28100525/transoesophageal-echocardiographic-evaluation-of-central-venous-catheter-positioning-using-peres-formula-or-a-radiological-landmark-based-approach-a-prospective-randomized-single-centre-study
#1
J H Ahn, I S Kim, J H Yang, I G Lee, D H Seo, S P Kim
BACKGROUND: The lower superior vena cava (SVC), near its junction with the right atrium (RA), is considered the ideal location for the central venous catheter tip to ensure proper function and prevent injuries. We determined catheter insertion depth with a new formula using the sternoclavicular joint and the carina as radiological landmarks, with a 1.5 cm safety margin. The accuracy of tip positioning with the radiological landmark-based technique (R) and Peres' formula (P) was compared using transoesophageal echocardiography...
February 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28099070/laparoscopic-rectal-dissection-assisted-by-transanal-endoluminal-videoendoscopy-through-a-blunt-tip-trocar
#2
Emanuele Asti, Andrea Lovece, Luigi Bonavina
BACKGROUND AND AIMS: Laparoscopic resection is a well-established approach for colorectal cancer surgery. In patients with rectal cancer treated by neoadjuvant chemoradiotherapy, it may be difficult to identify a clear safety margin for endostapling and subsequent anastomosis. We designed an innovative technical approach to assist colorectal anastomosis in these patients. TECHNIQUE: A four-trocar laparoscopic approach is used. After exploration of the abdominal cavity, the left colic flexure is completely mobilized...
January 18, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28095441/moving-model-test-of-high-speed-train-aerodynamic-drag-based-on-stagnation-pressure-measurements
#3
Mingzhi Yang, Juntao Du, Zhiwei Li, Sha Huang, Dan Zhou
A moving model test method based on stagnation pressure measurements is proposed to measure the train aerodynamic drag coefficient. Because the front tip of a high-speed train has a high pressure area and because a stagnation point occurs in the center of this region, the pressure of the stagnation point is equal to the dynamic pressure of the sensor tube based on the obtained train velocity. The first derivation of the train velocity is taken to calculate the acceleration of the train model ejected by the moving model system without additional power...
2017: PloS One
https://www.readbyqxmd.com/read/28095013/the-tipping-point-of-perceived-change-asymmetric-thresholds-in-diagnosing-improvement-versus-decline
#4
Ed O'Brien, Nadav Klein
Change often emerges from a series of small doses. For example, a person may conclude that a happy relationship has eroded not from 1 obvious fight but from smaller unhappy signs that at some point "add up." Everyday fluctuations therefore create ambiguity about when they reflect substantive shifts versus mere noise. Ten studies reveal an asymmetry in this first point when people conclude "official" change: people demand less evidence to diagnose lasting decline than lasting improvement, despite similar evidential quality...
February 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28094262/radiotherapy-and-immunotherapy-a-beneficial-liaison
#5
REVIEW
Ralph R Weichselbaum, Hua Liang, Liufu Deng, Yang-Xin Fu
Investigations into the interaction between radiotherapy and the host immune system have uncovered new mechanisms that can potentially be exploited to improve the efficacy of radiotherapy. Radiation promotes the release of danger signals and chemokines that recruit inflammatory cells into the tumour microenvironment, including antigen-presenting cells that activate cytotoxic T-cell function. By contrast, radiation can attract immunosuppressive cells into the tumour microenvironment. In rare circumstances, the antitumour effect of radiotherapy has been observed outside of the radiation field, known as the abscopal effect...
January 17, 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/28091777/ultrasonography-for-endotracheal-tube-position-in-infants-and-children
#6
REVIEW
Pooja Jaeel, Mansi Sheth, Jimmy Nguyen
: Ultrasonography (US) has been shown to be effective for verifying endotracheal tube (ETT) position in adults but has been less studied in infants and children. We review the literature regarding US for ETT positioning in the pediatric population. A literature search was conducted using the Ovid and MEDLINE databases with search terms regarding US relating to ETT intubation and positioning in infants and children. Most studies in neonates and infants used the midsagittal suprasternal view...
January 13, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28091427/evaluation-of-surface-characteristics-of-rotary-nickel-titanium-instruments-produced-by-different-manufacturing-methods
#7
U Inan, M Gurel
BACKGROUND: Instrument fracture is a serious concern in endodontic practice. OBJECTIVE: The aim of this study was to investigate the surface quality of new and used rotary nickel-titanium (NiTi) instruments manufactured by the traditional grinding process and twisting methods. MATERIALS AND METHODS: Total 16 instruments of two rotary NiTi systems were used in this study. Eight Twisted Files (TF) (SybronEndo, Orange, CA, USA) and 8 Mtwo (VDW, Munich, Germany) instruments were evaluated...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28089508/a-reply-to-douze-and-delagnes-s-the-pattern-of-emergence-of-a-middle-stone-age-tradition-at-gademotta-and-kulluletti-ethiopia-through-convergent-tool-and-point-technologies-j-hum-evol-91-2016-93-121
#8
Yonatan Sahle, David R Braun
Douze and Delagnes (2016) revisit Middle Stone Age (MSA) lithic assemblages from the Gademotta Formation (Fm.), Ethiopia. Their analysis of selected assemblages from three of the 1972 excavations expands the original typo-technological interpretations by Wendorf and Schild (1974). We particularly welcome their evaluation of our recent inferences about the function of pointed artifacts and technological patterns in the Gademotta Fm. (Sahle et al., 2013, 2014). However, we find several arguments and conclusions in Douze and Delagnes (2016) to be rather unconvincing and irreconcilable with results from analyses of whole assemblages (Wendorf and Schild, 1974; Sahle et al...
January 12, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28081273/assessing-the-impact-of-retreat-mechanisms-in-a-simple-antarctic-ice-sheet-model-using-bayesian-calibration
#9
Kelsey L Ruckert, Gary Shaffer, David Pollard, Yawen Guan, Tony E Wong, Chris E Forest, Klaus Keller
The response of the Antarctic ice sheet (AIS) to changing climate forcings is an important driver of sea-level changes. Anthropogenic climate change may drive a sizeable AIS tipping point response with subsequent increases in coastal flooding risks. Many studies analyzing flood risks use simple models to project the future responses of AIS and its sea-level contributions. These analyses have provided important new insights, but they are often silent on the effects of potentially important processes such as Marine Ice Sheet Instability (MISI) or Marine Ice Cliff Instability (MICI)...
2017: PloS One
https://www.readbyqxmd.com/read/28078445/energy-dependent-expansion-of-177-caliber-hollow-point-air-gun-projectiles
#10
Ronald Werner, Benno Schultz, Britta Bockholdt, Axel Ekkernkamp, Matthias Frank
Amongst hundreds of different projectiles for air guns available on the market, hollow-point air gun pellets are of special interest. These pellets are characterized by a tip or a hollowed-out shape in their tip which, when fired, makes the projectiles expand to an increased diameter upon entering the target medium. This results in an increase in release of energy which, in turn, has the potential to cause more serious injuries than non-hollow-point projectiles. To the best of the authors' knowledge, reliable data on the terminal ballistic features of hollow-point air gun projectiles compared to standard diabolo pellets have not yet been published in the forensic literature...
January 11, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28076396/neutrophil-interactions-stimulate-evasive-hyphal-branching-by-aspergillus-fumigatus
#11
Felix Ellett, Julianne Jorgensen, Galit H Frydman, Caroline N Jones, Daniel Irimia
Invasive aspergillosis (IA), primarily caused by Aspergillus fumigatus, is an opportunistic fungal infection predominantly affecting immunocompromised and neutropenic patients that is difficult to treat and results in high mortality. Investigations of neutrophil-hypha interaction in vitro and in animal models of IA are limited by lack of temporal and spatial control over interactions. This study presents a new approach for studying neutrophil-hypha interaction at single cell resolution over time, which revealed an evasive fungal behavior triggered by interaction with neutrophils: Interacting hyphae performed de novo tip formation to form new hyphal branches, allowing the fungi to avoid the interaction point and continue invasive growth...
January 11, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28069085/endoscopic-ear-surgery-a-hot-topic
#12
S Mitchell, C Coulson
OBJECTIVES: To summarise published research investigating maximal temperatures associated with endoscopes used in otology. Possible thermal issues surrounding the use of endoscopes in middle-ear surgery are discussed, and recommendations regarding the safest ways to use endoscopes in endoscopic ear surgery are made. METHODS: A non-systematic review of the relevant literature was conducted, with descriptive analysis and presentation of the results. RESULTS: There are currently no reports of any temperature-related deleterious effects in patients having undergone endoscopic ear surgery...
January 10, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28068061/looking-at-photoinduced-charge-transfer-processes-in-the-ir-answers-to-several-long-standing-questions
#13
Bogdan Dereka, Marius Koch, Eric Vauthey
Because of its crucial role in many areas of science and technology, photoinduced electron transfer is the most investigated photochemical reaction. Despite this, several important questions remain open. We present recent efforts to answer some of them, which concern both inter- and intramolecular processes. The decisive factor that allowed these issues to be successfully addressed was the use of time-resolved infrared (TRIR) spectroscopy. Many different transient species, such as tight and loose ion pairs (TIPs and LIPs) and exciplexes, have been invoked to explain the dynamics of intermolecular photoinduced charge separation reactions (i...
January 9, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28059543/emergent-conformal-symmetry-and-geometric-transport-properties-of-quantum-hall-states-on-singular-surfaces
#14
T Can, Y H Chiu, M Laskin, P Wiegmann
We study quantum Hall states on surfaces with conical singularities. We show that the electronic fluid at the cone tip possesses an intrinsic angular momentum, which is due solely to the gravitational anomaly. We also show that quantum Hall states behave as conformal primaries near singular points, with a conformal dimension equal to the angular momentum. Finally, we argue that the gravitational anomaly and conformal dimension determine the fine structure of the electronic density at the conical point. The singularities emerge as quasiparticles with spin and exchange statistics arising from adiabatically braiding conical singularities...
December 23, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/28057932/dynamic-versus-static-biomarkers-in-cancer-immune-checkpoint-blockade-unravelling-complexity
#15
W Joost Lesterhuis, Anthony Bosco, Michael J Millward, Michael Small, Anna K Nowak, Richard A Lake
Recently, there has been a coordinated effort from academic institutions and the pharmaceutical industry to identify biomarkers that can predict responses to immune checkpoint blockade in cancer. Several biomarkers have been identified; however, none has reliably predicted response in a sufficiently rigorous manner for routine use. Here, we argue that the therapeutic response to immune checkpoint blockade is a critical state transition of a complex system. Such systems are highly sensitive to initial conditions, and critical transitions are notoriously difficult to predict far in advance...
January 6, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28052381/the-lateral-calcaneal-artery-as-an-alternative-recipient-vessel-option-for-heel-and-lateral-foot-reconstruction
#16
Kyong-Je Woo, Jin-Woo Park, Goo-Hyun Mun
BACKGROUND: Clinical outcomes of consecutive use of the lateral calcaneal artery (LCA) as a recipient vessel for microsurgical reconstruction have not been reported. This study aimed to evaluate the feasibility and safety of the LCA as a recipient vessel for microsurgical foot reconstruction based on anatomical study of CT angiography and clinical results of using this vessel as the recipient. METHODS: Anatomic study was performed using CT angiography of 61 lower extremities (31 patients)...
January 4, 2017: Microsurgery
https://www.readbyqxmd.com/read/28048658/su-f-t-166-on-the-nature-of-the-background-visible-light-observed-in-fiber-optic-dosimetry-of-proton-beams
#17
A Darafsheh, R Taleei, A Kassaee, J Finlay
PURPOSE: The nature of the background visible light observed during fiber optic dosimetry of proton beams, whether it is due to Cherenkov radiation or not, has been debated in the literature recently. In this work, experimentally and by means of Monte Carlo simulations, we shed light on this problem and investigated the nature of the background visible light observed in fiber optics irradiated with proton beams. METHODS: A bare silica fiber optics was embedded in tissue-mimicking phantoms and irradiated with clinical proton beams with energies of 100-225 MeV at Roberts Proton Therapy Center...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047527/su-f-t-675-down-regulating-the-expression-of-cdc42-and-inhibition-of-migration-of-a549-with-combined-treatment-of-ionizing-radiation-and-sevoflurane
#18
Y Feng, J Feng, Z Huang
PURPOSE: Cdc42 is involved in cell transformation, proliferation, invasion and metastasis of human cancer cells. Cdc42 overexpression has been reported in several types of cancers. This study investigated the combined treatment effects of ionizing radiation and sevoflurane on down-regulating Cdc42 expression and suppressing migration of human adenocarcinoma cell line A549. METHODS: Samples of A549 cells with Cdc42 overexpression were created and Cdc42 expression was determined by Western blotting...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047382/mo-fg-campus-tep1-02-facial-recognition-and-recall-using-kinect-v2-for-patient-verification
#19
E Silverstein, M Snyder
PURPOSE: Investigate capability and accuracy of the Kinect v2 camera for facial recognition to use as a tool for patient check-in upon arrival, as well as patient verification when entering treatment vault. METHODS: The Kinect software has a native facial recognition feature which recognizes major facial landmarks (eyes, nose, mouth, etc). 1347 facial vertices are automatically generated, each located at a specific facial point at standardized distances between points...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046783/su-f-t-20-novel-catheter-lumen-recognition-algorithm-for-rapid-digitization
#20
J Dise, D McDonald, M Ashenafi, J Peng, C Mart, N Koch, K Vanek
PURPOSE: Manual catheter recognition remains a time-consuming aspect of high-dose-rate brachytherapy (HDR) treatment planning. In this work, a novel catheter lumen recognition algorithm was created for accurate and rapid digitization. METHODS: MatLab v8.5 was used to create the catheter recognition algorithm. Initially, the algorithm searches the patient CT dataset using an intensity based k-means filter designed to locate catheters. Once the catheters have been located, seed points are manually selected to initialize digitization of each catheter...
June 2016: Medical Physics
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