Sergei V Shekhovtsov, Yana L Vorontsova, Irina A Slepneva, Dmitry N Smirnov, Ekaterina E Khrameeva, Alexey Shatunov, Tatiana V Poluboyarova, Nina A Bulakhova, Ekaterina N Meshcheryakova, Daniil I Berman, Viktor V Glupov
The Siberian frog Rana amurensis has a uniquely high tolerance to hypoxia among amphibians, as it is able to withstand several months underwater with almost no oxygen (0.2 mg/liter) vs. several days for other studied species. Since it was hypothesized that hypoxia actives the antioxidant defense system in hypoxia-tolerant animals, one would expect similar response in R. amurensis. Here, we studied the effect of hypoxia in the Siberian frog based on the transcriptomic data, activities of antioxidant enzyme, and content of low-molecular-weight antioxidants...
March 2024: Biochemistry. Biokhimii︠a︡