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Traumatic dissociation

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https://www.readbyqxmd.com/read/29151087/ganser-syndrome
#1
Sebastian Dieguez
Ganser's syndrome is a rare and controversial condition, whose main and most striking feature is the production of approximate answers (or near misses) to very simple questions. For instance, asked how many legs a horse has, Ganser patients will reply "5", and answers to plain arithmetic questions will likewise be wrong, but only slightly off the mark (e.g., 2 + 2 = 3). This symptom was originally described by Sigbert Ganser in 1897 in prisoners on remand and labeled Vorbeigehen ("to pass by"), although the term Vorbeireden ("to talk beside the point") is also frequently used...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29144883/what-was-once-essential-may-become-detrimental-the-mediating-role-of-depersonalization-in-the-relationship-between-childhood-emotional-maltreatment-and-psychological-distress-in-adults
#2
Aoife Ó Laoide, Jonathan Egan, Kristin Osborn
Depersonalization (DP) is a dissociative phenomenon, characterised by feeling "unreal" or detached from one's own emotions, thoughts and behaviour (APA, 2013). It is considered a defense mechanism, employed in response to overwhelming events, whereby thoughts and emotions are suppressed in order to enhance the individual's' capacity to function in traumatic environments. DP has been found to co-occur with anxiety and depressive disorders and childhood emotional maltreatment (EM) has been identified as an important predisposing factor...
November 16, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/29134717/superior-colliculus-resting-state-networks-in-post-traumatic-stress-disorder-and-its-dissociative-subtype
#3
Isadora Olivé, Maria Densmore, Sherain Harricharan, Jean Théberge, Margaret C McKinnon, Ruth Lanius
OBJECTIVES: The innate alarm system (IAS) models the neurocircuitry involved in threat processing in posttraumatic stress disorder (PTSD). Here, we investigate a primary subcortical structure of the IAS model, the superior colliculus (SC), where the SC is thought to contribute to the mechanisms underlying threat-detection in PTSD. Critically, the functional connectivity between the SC and other nodes of the IAS remains unexplored. EXPERIMENTAL DESIGN: We conducted a resting-state fMRI study to investigate the functional architecture of the IAS, focusing on connectivity of the SC in PTSD (n = 67), its dissociative subtype (n = 41), and healthy controls (n = 50) using region-of-interest seed-based analysis...
November 13, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29128558/effects-of-35-carbon-dioxide-co2-inhalation-in-patients-with-post-traumatic-stress-disorder-ptsd-a-double-blind-randomized-placebo-controlled-cross-over-trial
#4
Michael Kellner, Christoph Muhtz, Sven Nowack, Irina Leichsenring, Klaus Wiedemann, Alexander Yassouridis
BACKGROUND: In patients with post-traumatic stress disorder (PTSD) two open pilot studies about the effects of 35% carbon dioxide (CO2) exist. One shows an augmented panicogenic and anxiogenic response (Muhtz et al., 2011), the other does not (Talesnik et al. 2007). We further characterized the CO2 reactivity in PTSD using for the first time placebo-controlled and double-blind conditions. METHODS: In 20 patients with PTSD we assessed panic, anxiety, dissociative and PTSD symptoms after a single vital capacity inhalation of 35% CO2 compared to a placebo gas condition in a within-participant cross-over, placebo-controlled, double-blind and randomized design...
October 31, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29125800/the-trauma-factor-examining-the-relationships-among-different-types-of-trauma-dissociation-and-psychopathology
#5
Adriano Schimmenti
Extensive research has reported a dose-response relationship between exposure to trauma and the severity of both dissociation and psychopathology. However, certain types of trauma may co-occur more frequently than others and specific combinations of traumatic experiences may relate differently to dissociative processes and psychiatric symptoms. In the current study, 359 adult participants completed questionnaires on traumatic experiences, dissociation, and psychopathology. A correlation network analysis showed that some types of trauma are more likely to co-occur and that especially traumatic experiences in attachment relationships during childhood were significantly associated with other trauma in life...
November 10, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/29117838/the-te-technique-for-restoring-fingertip-stability-post-traumatic-acro-osteolysis-a-report-and-review-of-management-options
#6
Yu-Te Lin, Charles Yuen Yung Loh
BACKGROUND: Fractures of the distal phalanx can result in bony non-union, resulting in acro-osteolysis and subsequent fingertip instability due to soft tissue dissociation from bone. Conventional methods of treating this involve osseous fixation, but do not address the laxity and lack of soft tissue stability with bone. Current techniques also do not address the management of such conditions if bony fragments are too small to reduce. We present a novel method that addresses both soft tissue and bony deformity in this condition...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29092782/psychopathological-constellation-in-patients-with-pnes-a-new-hypothesis
#7
Iolanda Martino, Antonella Bruni, Angelo Labate, Roberta Vasta, Antonio Cerasa, Giuseppe Borzì, Pasquale De Fazio, Antonio Gambardella
Depression symptoms have often reported in patients with psychogenic nonepileptic seizures (PNES), although the underlying psychopathological symptomatology has been poorly understood. Our aim was to compare constellations of psychological and behavioral disturbance in PNES with respect to patients with mild-major depressive disorder (MDD), hypothesizing that the construct of depression might be different in the two groups. Ten patients with PNES and ten sex-/age-matched patients with mild-MDD newly-diagnosed, were enrolled in this study...
October 29, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29080235/cortical-thickness-alterations-linked-to-somatoform-and-psychological-dissociation-in-functional-neurological-disorders
#8
David L Perez, Nassim Matin, Benjamin Williams, Kaloyan Tanev, Nikos Makris, W Curt LaFrance, Bradford C Dickerson
BACKGROUND: Links between dissociation and functional neurological disorder (FND)/conversion disorder are well-established, yet the pathophysiology of dissociation remains poorly understood. This MRI study investigated structural alterations associated with somatoform and psychological dissociation in FND. We hypothesized that multimodal, paralimbic cingulo-insular regions would relate to the severity of somatoform dissociation in patients with FND. METHODS: FreeSurfer cortical thickness and subcortical volumetric analyses were performed in 26 patients with motor FND and 27 matched healthy controls...
October 28, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29063485/the-dissociative-subtype-of-post-traumatic-stress-disorder-research-update-on-clinical-and-neurobiological-features
#9
Jytte van Huijstee, Eric Vermetten
Recently, a dissociative subtype of post-traumatic stress disorder (PTSD) has been included in the DSM-5. This review focuses on the clinical and neurobiological features that distinguish the dissociative subtype of PTSD from non-dissociative PTSD. Clinically, the dissociative subtype of PTSD is associated with high PTSD severity, predominance of derealization and depersonalization symptoms, a more significant history of early life trauma, and higher levels of comorbid psychiatric disorders. Furthermore, PTSD patients with dissociative symptoms exhibit different psychophysiological and neural responses to the recall of traumatic memories...
October 21, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/29052121/co-occurring-posttraumatic-stress-disorder-and-depression-among-young-children
#10
Alison Salloum, Carly Johnco, Kristin M Smyth, Tanya K Murphy, Eric A Storch
The purpose of this study was to examine differences in: (1) mental health emotional and behavioral problems between young children experiencing PTSD with and without MDD; (2) the incidence of caregiver PTSD and MDD between children with PTSD ± MDD; and (3) the number of traumatic events and interpersonal versus non-interpersonal nature of trauma events among children whose parents sought child trauma-focused treatment. Sixty-six caregivers of children aged 3-7 with PTSD completed semi-structured interviews regarding caregiver and child diagnoses, and caregivers completed self-report measures regarding child symptomatology...
October 19, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29050383/early-detection-of-consciousness-in-patients-with-acute-severe-traumatic-brain-injury
#11
Brian L Edlow, Camille Chatelle, Camille A Spencer, Catherine J Chu, Yelena G Bodien, Kathryn L O'Connor, Ronald E Hirschberg, Leigh R Hochberg, Joseph T Giacino, Eric S Rosenthal, Ona Wu
See Schiff (doi:10.1093/awx209) for a scientific commentary on this article. Patients with acute severe traumatic brain injury may recover consciousness before self-expression. Without behavioural evidence of consciousness at the bedside, clinicians may render an inaccurate prognosis, increasing the likelihood of withholding life-sustaining therapies or denying rehabilitative services. Task-based functional magnetic resonance imaging and electroencephalography techniques have revealed covert consciousness in the chronic setting, but these techniques have not been tested in the intensive care unit...
September 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29049948/altered-responsiveness-in-psychogenic-nonepileptic-seizures-and-its-implication-to-underlying-psychopathology
#12
Gaston Baslet, Benjamin Tolchin, Barbara A Dworetzky
PURPOSE: Altered responsiveness during psychogenic nonepileptic seizures (PNES) is a distinct semiological feature that may signal a psychological vulnerability. We hypothesized that altered responsiveness is related to difficulties with emotion tolerance, experiential avoidance, difficulty coping, dissociation and trauma and prior experiences of loss of awareness. METHODS: 71 patients with video-EEG confirmed PNES were divided into two groups based on their responsiveness at the time of the captured event during long-term monitoring...
October 13, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29043544/icp-versus-laser-doppler-cerebrovascular-reactivity-indices-to-assess-brain-autoregulatory-capacity
#13
F A Zeiler, J Donnelly, D Cardim, D K Menon, P Smielewski, M Czosnyka
BACKGROUND: To explore the relationship between various autoregulatory indices in order to determine which approximate small vessel/microvascular (MV) autoregulatory capacity most accurately. METHODS: Utilizing a retrospective cohort of traumatic brain injury patients (N = 41) with: transcranial Doppler (TCD), intracranial pressure (ICP) and cortical laser Doppler flowmetry (LDF), we calculated various continuous indices of autoregulation and cerebrovascular responsiveness: A...
October 17, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/29028150/potential-of-micrornas-as-novel-targets-in-the-alleviation-of-pathological-fear
#14
REVIEW
Conor P Murphy, Nicolas Singewald
The current treatment of post-traumatic stress disorder (PTSD), phobias and other anxiety disorders, remains insufficient particularly in producing long-lasting full symptom control. Dysfunctional fear processing is common in these disorders, including a deficiency in fear-inhibitory mechanisms and impairment in the ability to discriminate between safety and danger cues. Research has aimed to elucidate brain circuitries, neurotransmitters and downstream signaling pathways important in the alleviation of aberrant fear, with a specific focus on mechanisms modulating fear memory and its behavioral expression...
October 13, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29027871/weak-evidence-for-increased-motivated-forgetting-of-trauma-related-words-in-dissociated-or-traumatised-individuals-in-a-directed-forgetting-experiment
#15
Lawrence Patihis, Patricia J Place
Motivated forgetting is the idea that people can block out, or forget, upsetting or traumatic memories, because there is a motivation to do so. Some researchers have cited directed forgetting studies using trauma-related words as evidence for the theory of motivated forgetting of trauma. In the current article subjects used the list method directed forgetting paradigm with both trauma-related words and positive words. After one list of words was presented subjects were directed to forget the words previously learned, and they then received another list of words...
October 13, 2017: Memory
https://www.readbyqxmd.com/read/28986644/traumatic-occipito-cervical-dissociation-in-adults-a-middle-eastern-cohort-study
#16
K Venugopal Menon, Ismail Al Habsi, Khalifa Al Ghafri
The objective of this study is to describe a series of cranio-cervical dissociation victims and evaluate their outcomes as well as discuss the clinical dilemmas we faced in the context of current literature evidence. This is a retrospective cohort study of traumatic occipito-cervical dissociation in five patients (three males and two females) encountered between 2010 and 2016 at a tertiary care facility in the Middle East region. All patients underwent occipito-cervical fusion using screws and rods system with mean postoperative follow-up period of 2...
October 6, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28960132/in-vivo-monitoring-of-infectious-diseases-in-living-animals-using-bioluminescence-imaging
#17
Asheesh Gupta, Pinar Avci, Mahdi Karimi, Magesh Sadasivam, Wanessa C Antunes-Melo, Elisa Carrasco, Michael R Hamblin
Traditional methods of localizing and quantifying the presence of pathogenic microorganisms in living experimental animal models of infections have mostly relied on sacrificing the animals, dissociating the tissue and counting the number of colony forming units. However the discovery of several varieties of the light producing enzyme, luciferase, and the genetic engineering of bacteria, fungi, parasites and mice to make them emit light, either after administration of the luciferase substrate, or in the case of the bacterial lux operon without any exogenous substrate, has provided a new alternative...
September 29, 2017: Virulence
https://www.readbyqxmd.com/read/28926159/randomized-controlled-feasibility-trial-of-intranasal-ketamine-compared-to-intranasal-fentanyl-for-analgesia-in-children-with-suspected-extremity-fractures
#18
Stacy L Reynolds, Kathleen K Bryant, Jonathan R Studnek, Melanie Hogg, Connell Dunn, Megan A Templin, Charity G Moore, James R Young, Katherine Rivera Walker, Michael S Runyon
OBJECTIVES: We compared the tolerability and efficacy of intranasal subdissociative ketamine to intranasal fentanyl for analgesia of children with acute traumatic pain and investigated the feasibility of a larger noninferiority trial that could investigate the potential opioid-sparing effects of intranasal ketamine. METHODS: This randomized controlled trial compared 1 mg/kg intranasal ketamine to 1.5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016...
September 19, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28911803/sensory-overload-and-imbalance-resting-state-vestibular-connectivity-in-ptsd-and-its-dissociative-subtype
#19
Sherain Harricharan, Andrew A Nicholson, Maria Densmore, Jean Théberge, Margaret C McKinnon, Richard W J Neufeld, Ruth A Lanius
BACKGROUND: The vestibular system integrates multisensory information to monitor one's bodily orientation in space, and is influenced by interoceptive awareness. Post-traumatic stress disorder (PTSD) involves typically alterations in interoceptive and bodily self-awareness evidenced by symptoms of hyperarousal, as well as of emotional detachment, including emotional numbing, depersonalization, and derealization. These alterations may disrupt vestibular multisensory integration between the brainstem (vestibular nuclei) and key vestibular cortical regions (parieto-insular vestibular cortex, prefrontal cortex)...
September 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28884713/-mental-disorders-in-patients-with-breast-cancer-a-differentiated-approach-to-the-study-of-nozogeny
#20
O V Shushpanova
AIM: To study mental disorders in patients with breast cancer (BC) at different stages of the disease taking into account premorbid characteristics and psychosomatic correlations in their development. MATERIAL AND METHODS: The study included 82 patients with histologically confirmed BC. The first group consisted of 30 patients (mean age 49.7±11.1 years) with the first established diagnosis of BC and mental disorders caused by somatic disease (ICD-10 F40-F48, stress-related neurotic and somatoform disorders)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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