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https://www.readbyqxmd.com/read/29223888/neighborhood-crime-undermines-parenting-violence-in-the-vicinity-of-households-as-a-predictor-of-aggressive-discipline
#1
Jorge Cuartas
Child discipline is a central component of parent-child interactions. Evidence suggests corporal discipline impairs children's physical, cognitive, and socioemotional development and compromises their future chances, especially since it is more frequently used against at-risk children. Using geocoded data for 1209 children under the age of five and their mothers, this study analyses the relation between the occurrence of crimes in close proximity to households in four major urban municipalities of Colombia and a particularly violent corporal discipline practice: hitting children with objects...
December 7, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29196472/first-person-ana-nascimento
#2
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Ana Nascimento is the first author on 'KIF13A mediates trafficking of influenza A virus ribonucleoproteins', published in Journal of Cell Science. Ana conducted the work in this article in Maria João Amorim's lab at the Instituto Gulbenkian de Ciência, Portugal. She is now a PhD student in the lab of Beate Sodeik at the Institute of Virology at Hannover Medical School, investigating host-pathogen interactions, particularly involving viruses...
December 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29166394/maternity-care-for-trafficked-women-survivor-experiences-and-clinicians-perspectives-in-the-united-kingdom-s-national-health-service
#3
Debra Bick, Louise M Howard, Sian Oram, Cathy Zimmerman
BACKGROUND: Although trafficked women and adolescents are at risk of unprotected or forced sex, there is little research on maternity care among trafficking survivors. We explored health care needs, service use and challenges among women who became pregnant while in the trafficking situation in the United Kingdom (UK) and clinicians' perspectives of maternity care for trafficked persons. METHODS: Cross-sectional survey and qualitative interviews with trafficking survivors recruited from statutory and voluntary sector organisations in England and qualitative interviews with maternity clinicians and family doctors undertaken to offer further insight into experiences reported by these women...
2017: PloS One
https://www.readbyqxmd.com/read/29095121/survivors-voices-complex-needs-of-sex-trafficking-survivors-in-the-midwest
#4
Sriyani Tidball, Shireen S Rajaram
Human trafficking is a serious public health issue and has long-term physical, mental, social, and economic consequences for survivors, their families, and communities. The Victims of Trafficking and Violence Protection Act of 2000 defines sex trafficking as a commercial sex act that is induced by force, fraud or coercion, or when a commercial sex act involves a person below 18 years of age. There is inadequate research from the perspectives of survivors. The purpose of this study was to gather data from survivors on their complex needs...
November 2, 2017: Behavioral Medicine
https://www.readbyqxmd.com/read/29027216/the-long-pentraxin-ptx3-a-prototypical-sensor-of-tissue-injury-and-a-regulator-of-homeostasis
#5
REVIEW
Marco Erreni, Angelo A Manfredi, Cecilia Garlanda, Alberto Mantovani, Patrizia Rovere-Querini
Tissue damage frequently occurs. The immune system senses it and enforces homeostatic responses that lead to regeneration and repair. The synthesis of acute phase molecules is emerging as a crucial event in this program. The prototypic long pentraxin PTX3 orchestrates the recruitment of leukocytes, stabilizes the provisional matrix in order to facilitate leukocyte and stem progenitor cells trafficking, promotes swift and safe clearance of dying cells and of autoantigens, limiting autoimmunity and protecting the vasculature...
November 2017: Immunological Reviews
https://www.readbyqxmd.com/read/29024922/isolation-and-whole-genome-analysis-of-endospore-forming-bacteria-from-heroin
#6
Jörn Kalinowski, Björn Ahrens, Arwa Al-Dilaimi, Anika Winkler, Daniel Wibberg, Uwe Schleenbecker, Christian Rückert, Roman Wölfel, Gregor Grass
Infections caused by endospore-forming bacteria have been associated with severe illness and death among persons who inject drugs. Analysis of the bacteria residing in heroin has thus been biased towards species that affect human health. Similarly, exploration of the bacterial diversity of seized street market heroin correlated with the skin microflora of recreational heroin users insofar as different Staphylococus spp. or typical environmental endospore formers including Bacillus cereus and other Bacilli outside the B...
October 4, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28966163/first-person-brandy-hyndman-and-mathieu-crupi
#7
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Brandy Hyndman and Mathieu Crupi are co-first authors on 'Differential recruitment of E3 ubiquitin ligase complexes regulates RET isoform internalization', published in Journal of Cell Science. Brandy is a Research Associate and Mathieu is a PhD student, both in the lab of Dr Lois Mulligan at the Queen's University Cancer Research Institute in Kingston, ON, Canada, investigating the ubiquitylation and trafficking of RET receptor tyrosine kinase isoforms...
October 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28945674/trafficking-and-trauma-insight-and-advice-for-the-healthcare-system-from-sex-trafficked-women-incarcerated-on-rikers-island
#8
Anita Ravi, Megan R Pfeiffer, Zachary Rosner, Judy A Shea
BACKGROUND: Sex-trafficked persons experience significant trauma while exploited, resulting in complex health issues and barriers to health care. Incorporating survivor perspectives is critical in optimizing health care delivery for this population. OBJECTIVES: We interviewed sex-trafficking survivors regarding their experiences with trauma while being trafficked and elicited advice about health care delivery. RESEARCH DESIGN: Qualitative interviews were conducted in New York City's Rikers Island jail from July to September 2015...
December 2017: Medical Care
https://www.readbyqxmd.com/read/28904806/do-clinicians-receive-adequate-training-to-identify-trafficked-persons-a-scoping-review-of-nhs-foundation-trusts
#9
Charles Dr Thompson, Arun Mahay, David Stuckler, Sarah Steele
OBJECTIVE: We investigate whether physicians in secondary care in the English NHS receive adequate training to recognise and appropriately refer for services those persons suspected to be victims of human trafficking. DESIGN: Freedom of Information requests were sent to the 105 England's NHS Trusts delivering acute care in England. SETTING: NHS Trusts providing secondary care in England. PARTICIPANTS: English NHS Trusts...
September 2017: JRSM Open
https://www.readbyqxmd.com/read/28833117/an-evidence-based-forensic-taxonomy-of-windows-phone-communication-apps
#10
Niken Dwi Wahyu Cahyani, Ben Martini, Kim-Kwang Raymond Choo, Nurul Hidayah Ab Rahman, Helen Ashman
Communication apps can be an important source of evidence in a forensic investigation (e.g., in the investigation of a drug trafficking or terrorism case where the communications apps were used by the accused persons during the transactions or planning activities). This study presents the first evidence-based forensic taxonomy of Windows Phone communication apps, using an existing two-dimensional Android forensic taxonomy as a baseline. Specifically, 30 Windows Phone communication apps, including Instant Messaging (IM) and Voice over IP (VoIP) apps, are examined...
August 17, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28806461/talking-to-adolescents-about-social-media
#11
Rachel S Dawson
I see a large number of adolescents in my clinic with issues related to their social media use. These issues range from lack of sleep, to depression, to cyberbullying, and even sex trafficking, all secondary to constant social media exposure. Pediatricians should ask about social media use when they see children and adolescents who already have access to electronic devices. They should also ask parents about controls that are set in place to monitor social media use, content, and friend connections on those sites...
August 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28800810/international-emergency-psychiatry-challenges-disaster-medicine-war-human-trafficking-displaced-persons
#12
REVIEW
Michael Jaung, Suni Jani, Sophia Banu, Joy M Mackey
Mental health disorders are a major cause of morbidity and a growing burden in low-income and middle-income countries; but there is little existing literature on the detailed epidemiology, diagnosis, and treatment in low-resource settings. Special situations with vulnerable populations, such as those created by international humanitarian emergencies, refugees or internally displaced people, and victims of human trafficking, are increasing in prevalence. These victims are often resettled in developed countries and come to the emergency department seeking care...
September 2017: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28765291/first-person-nicola-stevenson-and-ian-white
#13
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Nicola Stevenson and Ian White are co-first authors on 'Clathrin-mediated post-fusion membrane retrieval influences the exocytic mode of endothelial Weibel-Palade bodies', published in this issue of Journal of Cell Science. Dr Stevenson is a Research Associate at the University of Bristol, UK, investigating mechanisms of collagen trafficking, and Dr White is an electron microscopist at the MRC Laboratory for Molecular Cell Biology at University College London, UK...
August 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28756336/tnf%C3%AE-and-il-1%C3%AE-in-the-synovial-fluid-facilitate-mucosal-associated-invariant-t-mait-cell-migration
#14
Miok Kim, Su-Jin Yoo, Seong Wook Kang, Jaeyul Kwon, Inpyo Choi, Chang Hoon Lee
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affect the joints and inflammatory cell migration into inflamed articular sites contribute to this disease. Among the inflammatory cells, human mucosal-associated invariant T (MAIT) cells were recently recognized as critical cellular component with a pathological role in RA. However, their migratory characteristics are poorly understood. The aim of this study was to determine whether human MAIT cells preferentially traffick to inflamed synovial sites in rheumatoid arthritis patients and to elucidate the underlying mechanism...
July 27, 2017: Cytokine
https://www.readbyqxmd.com/read/28697094/identifying-and-assisting-sexually-exploited-and-trafficked-patients-seeking-women-s-health-care-services
#15
Erin E Tracy, Wendy Macias-Konstantopoulos
It is estimated that 21 million people are trafficked worldwide, including 11.4 million women and girls. Approximately 4.5 million are forced to do sexual labor. The exact prevalence of human trafficking is difficult to ascertain, however, given the limitations of data collection in an illegal industry. Obstetrician-gynecologists should not only be aware of the widespread nature of human trafficking, but also have the tools to assess patients for trafficking and respond to victim identifications. Patients may present with signs of physical abuse, depression, anxiety, posttraumatic stress disorder, substance use, sexually transmitted infections, pregnancy, and nonspecific somatic complaints...
August 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28544095/phenotypic-assays-for-mycobacterium-tuberculosis-infection
#16
Ok-Ryul Song, Nathalie Deboosere, Vincent Delorme, Christophe J Queval, Gaspard Deloison, Elisabeth Werkmeister, Frank Lafont, Alain Baulard, Raffaella Iantomasi, Priscille Brodin
Tuberculosis (TB) is still a major global threat, killing more than one million persons each year. With the constant increase of Mycobacterium tuberculosis strains resistant to first- and second-line drugs, there is an urgent need for the development of new drugs to control the propagation of TB. Although screenings of small molecules on axenic M. tuberculosis cultures were successful for the identification of novel putative anti-TB drugs, new drugs in the development pipeline remains scarce. Host-directed therapy may represent an alternative for drug development against TB...
October 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28543168/a-new-tool-to-tackle-the-opioid-epidemic-description-utility-and-results-from-the-maine-diversion-alert-program
#17
Brian J Piper, Clare E Desrosiers, Harriet C Fisher, Kenneth L McCall, Stephanie D Nichols
STUDY OBJECTIVE: The opioid epidemic continues to impact the United States, and new strategies are needed to combat this epidemic. The objective of this study was to analyze 2015 drug arrest data from Maine's Diversion Alert (DA) program (diversionalert.org), compare arrest data between the first quarters of 2015 and 2016, and provide an analysis of the sex differences in the arrests as well as information about DA use. STUDY DESIGN: This was a population-based descriptive study using data from the Maine DA program...
July 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28523588/advances-in-the-development-of-janus-kinase-inhibitors-in-inflammatory-bowel-disease-future-prospects
#18
REVIEW
Mathurin Flamant, Josselin Rigaill, Stephane Paul, Xavier Roblin
Inflammatory bowel disease (IBD) is caused by a dysregulation of the immune system, inducing the production of proinflammatory cytokines and adhesion molecules. A better understanding of the mucosal immune response in IBD has led to the development of new drugs directed at inflammatory cytokines and leukocyte-trafficking molecules. Beyond tumor necrosis factor antagonists and anti-integrin molecules, which act by blocking the interaction between gut-specific lymphocytes and their receptor on vascular endothelium, the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway represents a new target in IBD...
July 2017: Drugs
https://www.readbyqxmd.com/read/28510328/genetic-variants-in-the-genes-encoding-rho-gtpases-and-related-regulators-predict-cutaneous-melanoma-specific-survival
#19
Shun Liu, Yanru Wang, William Xue, Hongliang Liu, Yinghui Xu, Qiong Shi, Wenting Wu, Dakai Zhu, Christopher I Amos, Shenying Fang, Jeffrey E Lee, Terry Hyslop, Yi Li, Jiali Han, Qingyi Wei
Rho GTPases control cell division, motility, adhesion, vesicular trafficking and phagocytosis, which may affect progression and/or prognosis of cancers. Here, we investigated associations between genetic variants of Rho GTPases-related genes and cutaneous melanoma-specific survival (CMSS) by re-analyzing a published melanoma genome-wide association study (GWAS) and validating the results in another melanoma GWAS. In the single-locus analysis of 36,018 SNPs in 129 Rho-related genes, 427 SNPs were significantly associated with CMSS (p < 0...
August 15, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28490630/understanding-phospholipid-function-why-are-there-so-many-lipids
#20
REVIEW
William Dowhan
In the 1970s, phospholipids were still considered mere building blocks of the membrane lipid bilayer, but the subsequent realization that phospholipids could also serve as second messengers brought new interest to the field. My own passion for the unique amphipathic properties of lipids led me to seek other, non-signaling functions for phospholipids, particularly in their interactions with membrane proteins. This seemed to be the last frontier in protein chemistry and enzymology to be conquered. I was fortunate to find my way to Eugene Kennedy's laboratory, where both membrane proteins and phospholipids were the foci of study, thus providing a jumping-off point for advancing our fundamental understanding of lipid synthesis, membrane protein biosynthesis, phospholipid and membrane protein trafficking, and the cellular roles of phospholipids...
June 30, 2017: Journal of Biological Chemistry
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