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Paul Simusika, Allen C Bateman, Andros Theo, Geoffrey Kwenda, Christine Mfula, Edward Chentulo, Mwaka Monze
BACKGROUND: Morbidity and mortality from respiratory infections are higher in resource-limited countries than developed countries, but limited studies have been conducted in resource-limited settings to examine pathogens from patients with acute respiratory infections. Influenza surveillance has been conducted in Zambia since 2008; however, only 4.3% of patients enrolled in 2011-2012 were positive for influenza. Therefore, we examined non-influenza respiratory pathogens in children with severe acute respiratory illness (SARI) in Zambia, to estimate the scope of disease burden and determine commonly-identified respiratory pathogens...
2015: BMC Infectious Diseases
Lawrence Mugisha, Sophie Köndgen, Deogratias Kaddu-Mulindwa, Lynne Gaffikin, Fabian H Leendertz
Information on the chimpanzee nasopharygeal colonization in captive sanctuaries and in the wild is rare. This study was undertaken to establish the nasopharygeal colonization and potential bacterial pathogens in sanctuary chimpanzees as a basis for improving chimpanzee and employee health. Nasopharygeal colonization of 39 healthy chimpanzees were analyzed by microbiological cultivation method and polymerase chain reaction (PCR) targeting the bacterial 16S rRNA gene. We report four major phyla dominated by Proteobacteria (50%), Fermicutes (35...
February 2014: American Journal of Primatology
F Ö Eyüboğlu, E Küpeli, S S Bozbaş, Z E Ozen, E S Akkurt, C Aydoğan, G Ulubay, S Akçay, M Haberal
BACKGROUND: Recipients of solid organ transplants (SOTs) are at higher risk to develop pulmonary infections (PIs) owing to their immunocompromised state. Flexible bronchoscopy (FB) is frequently performed to diagnose nature of these infections. The aim of 12-year review was to evaluate the demographic characteristics of SOT recipients with PIs and to study diagnostic utility of FB in this group of patients. METHODS: Medical records of patients who underwent SOT as well as FB between 2000 and 2012 were retrospectively reviewed...
2013: Transplantation Proceedings
Lais Pinto de Almeida, Fabiana Puerro de Carvalho, Alexandre Gimenes Marques, Andrea Dos Santos Pereira, Renata Puzzo Bortoleto, Marinês Dalla Valle Martino
OBJECTIVE: To evaluate ertapenem disk performance to predict Klebsiella pneumonie carbapenemase production by Gram-negative bacilli. METHODS: All Gram-negative bacilli isolated between January 2010 and June 2011 were tested by disk diffusion (Oxoid™) for sensitivity to ertapenem, meropenem and imipenem. Resistant or intermediate sensitivity strains (diameter < 22 mm for ertapenem) were also tested for the blaKPC gene by polymerase chain reaction. Disk predictive positive value for Klebsiella pneumoniae carbapenemase and specificity were calculated...
October 2012: Einstein
Pornchai Simaroj, Suvicha Kompreyarat, Pitak Santanirand, Kaevalin Lekhanont
OBJECTIVE: To determine the rate of anterior chamber contamination during phacoemulsification after applying 5% povidone-iodine prior to surgery. MATERIAL AND METHOD: One hundred eyes from 100 patients having phacoemulsification cataract surgery by a single surgeon at Ramathibodi Hospital between October 2010 and March 2011 were included in the present study. Povidone-iodine 5% solution eye drops were used in all patients at least three minutes before the operation...
May 2012: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Y-T Lee, S-C Kuo, S-P Yang, Y-T Lin, D-H Chiang, F-C Tseng, T-L Chen, C-P Fung
The phenotypically indistinguishable Acinetobacter baumannii and Acinetobacter nosocomialis have become leading pathogens causing nosocomial pneumonia in critically ill patients. A. baumannii and A. nosocomialis nosocomial pneumonias were grouped as a single clinical entity previously. This study aimed to determine whether they are the same or a different clinical entity. A total of 121 patients with A. baumannii and 131 with A. nosocomialis bacteremic nosocomial pneumonia were included during an 8-year period...
July 2013: Clinical Microbiology and Infection
Cristina Tecu, Maria E Mihai, Viorel I Alexandrescu, Dumitru Orăşanu, Carmen Zapucioiu, Dumitru Matei, M Craiu, Alexis Cochino
UNLABELLED: The objective of this study was to investigate the percent of infections with adenovirus (ADV) in children who had pneumonia, acute bronchiolitis or viral respiratory infections and were admitted to two pediatrics hospitals in Bucharest (Grigore Alexandrescu Hospital and Alfred Rusescu Hospital). MATERIALS AND METHODS: HASH(0x2e9d3c8) SUBJECTS: 70 children aged one month - five years, admitted to the above mentioned pediatrics hospitals in Bucharest, who were negative for the Respiratory Syncytial Virus (RSV) and the human Metapneumovirus (hMPV) by Reverse Transcription -Polymerase Chain Reaction (RT-PCR)...
January 2012: Roumanian Archives of Microbiology and Immunology
Nura Suleiman Gwaram, Hapipah Mohd Ali, Hamid Khaledi, Mahmood Ameen Abdulla, A Hamid A Hadi, Thong Kwai Lin, Chai Lay Ching, Cher Lin Ooi
A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A...
2012: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ben Rao, Liao Yuan Zhang, Jian'an Sun, Gang Su, Dongzhi Wei, Ju Chu, Jiawen Zhu, Yaling Shen
Serratia marcescens has been proved to be a potential strain for industrial 2,3-butanediol production for its high yield, productivity, and other advantages. In this study, the genes slaA, slaB, slaC, and slaR were successfully cloned which were further confirmed to be encoding acetolactate decarboxylase, acetolactate synthase, 2,3-butanediol dehydrogenase, and a LysR-like regulator, respectively. Unlike in Klebsiella sp. or Klebsiella pneumonie and Vibrio sp. or Vibrio cholerae, the gene slaC is separated from other genes...
March 2012: Applied Microbiology and Biotechnology
Veljko Flego, Marina Kurpis, Flavija Milevoj-Ribić, Ljiljana Bulat-Kardum, Dubravka Matanić
We present a case of 23-year-old student misdiagnosed for two months. Radiological finding showed a pneumonial infiltrate of left lung lower lobe. Antibiotical therapy was not resulting in a radiological regression. Biopsy of the lung infiltrate by transthoracic computed tomography guided histology needle, showed granulomatous inflammation with necrosis. Bronchial aspirate received by bronchoscopy was positive in culture on Mycobacterium tuberculosis. After 6 months of antituberculotic therapy advance the complete regression of lung infiltrate...
December 2010: Collegium Antropologicum
G Barten, H Schütte, R Bals, M Pletz, G Rohde
Community-acquired pneumonia (CAP) is associated with significant morbidity and mortality. It ranks as the fourth leading cause of death in the Western industrialized countries. New insights in the epidemiology and pathogenesis, recent developments in diagnosis and risk-stratification, and current recommendations on prevention and therapy were presented at the symposium "Pneumonie 2010 - State of the Art", held in Kassel, Germany, on the 4. - 5. November 2010. This symposium was organized by the CAPNETZ STIFTUNG...
April 2011: Pneumologie
F Vyhnánek, V Adámková, V Duchác, V Teplan, T Jirásek
INTRODUCTION: Nosocomial, intra-abdominal infections are extremely serious conditions, considering possibilities for their early diagnosis, as well as for their effective therapy. Multiresistant bacteria (Enterobacteriacae producing extended-spectrum beta-lactamases - ESBL Escherichia coli, Klebsiella species, vancomycin-resistant enterococci [VRE], and methicillin-resistant Staphylococcus aureus [MRSA]) are frequently isolated as pathogens of these infections. Tygecycline is among the novel wide- spectrum antibiotics affecting multiresistant bacteria, which are being introduced in clinical practice...
September 2009: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
Izabela Szczerba, Katarzyna Gortat, Karol Majewski
The aim of this study was to determine a susceptibility of 223 clinical strains Klebsiella to 11 antimicrobial agents and occurrence ESBL-positive strains. These strains were isolated from clinical specimens during 2006 year. Susceptibility of these strains against antimicrobial agents was determined with disc diffusion method according to CLSI recommendation. None of the analysed strains was resistant to imipenem. The Klebsiella pneumonie strains were most frequently isolated from respiratory tract.
2009: Medycyna Doświadczalna i Mikrobiologia
Pasi Huttunen, Maija Lappalainen, Eeva Salo, Tuula Lönnqvist, Pia Jokela, Timo Hyypiä, Heikki Peltola
AIM: Except bacterial meningitis, the agents causing acute central nervous system (CNS) infections in children are disclosed in only approximately half of the cases, and even less in encephalitis. We studied the potential of modern microbiological assays to improve this poor situation. METHODS: In a prospective study during 3 years, all children attending hospital with suspected CNS infection were examined using a wide collection of microbiological tests using samples from the cerebrospinal fluid, serum, nasal swabs and stool...
August 2009: Acta Paediatrica
M Kyle Smoot, Robert G Hosey
Despite their general high level of health, athletes are not free from the threat of developing pulmonary infection. Prompt diagnosis and proper treatment are important given the effects of pulmonary infection upon athletic performance and time away from training. This article reviews common etiologies of community-acquired pneumonia and a more in-depth discussion of mycoplasma pneumonie and influenza. Current treatment guidelines, acute bronchitis, fungal pulmonary infection, and return to play principles also are discussed...
March 2009: Current Sports Medicine Reports
Ulrike Hügel
Although many different diseases may cause a pleural effusion the most common causes are congestive heart failure, pneumonie, and cancer. The first step in the diagnosis of pleural effusion is the distinction between exudates and transudates. Because of their high sensitivity Light's criteria, which differentiate transudative effusions from exudative effusions by measuring the levels of total protein and lactate dehydrogenase in the pleural fluid and serum, have become the standard method for making this distinction...
2007: Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg
Marcin Marcinkowski, Danuta Czarnecka, Marek Jastrzebski, Danuta Fedak, Kalina Kawecka-Jaszcz
BACKGROUND: Postmyocardial infarction left ventricular remodeling is modified by inflammatory processes and structural changes in the myocardium. Chlamydia pneumoniae (Chp) causes chronic myocyte infection, affects apoptosis and TNF-alpha production, and may induce cross reactivity with alpha myosin. This is the way in which this intracellular pathogen may modulate remodeling on the cellular and organ level. MATERIAL AND METHODS: The study was conducted in 101 patients with a first myocardial infarction in whom we evaluated the serological features of Chp infection using the ELISA method and echocardiographic left ventricular volume at 10 days and 10 weeks after the infarction...
2006: Przegla̧d Lekarski
K Zeman
Atherosclerosis is guided by chronicle inflammation process. In the last decades of the 20th century, studies considering infection another possible risk factor of atherosclerosis development were written. Helicobacter pylori, Porphyromas gingivalis, some viruses but most frequently Chlamydia pneumonie are infection agens mentioned in these studies. Some of them emphasize also combined infections caused by more pathogenic factors having influence on vascular inflammation. Serological, epidemiological, histological and imunological studies show the pathogenic influence of acute or chronic infections...
September 2006: Vnitr̆ní Lékar̆ství
Magnús Gottfredsson, Hlíf Steingrímsdóttir
A 46-year-old previously healthy woman was diagnosed with acute lymphoblastic leukaemia. The induction phase was complicated by alpha-haemolytic streptococcal bacteremia which responded to antibacterial therapy. Subsequently, the patient developed pneumonie due to Chlamydiapneumoniae which responded to macrolides. Following this infection the patient developed recurrent fever and new pulmonary infiltrates were noted. Bronchoscopy was performed and treatment was administered with liposomal amphotericin B (L-AmB, AmBisome) for two days, but was complicated by acute renal failure...
2006: Acta Bio-medica: Atenei Parmensis
S Paolini, A Raco, D Di Stefano, V Esposito, P Ciappetta
We report the intramedullary growth of a malignant peripheral nerve sheath tumour (MPNST). A 50year-old man developed a severe tetraparesis over a 4-month period. Following irradiation of a chronic tonsillitis during his childhood, the patient had later experienced a number of post-radiation diseases, including a laryngeal cancer that required permanent tracheotomy. Before admission, a magnetic resonance imaging (MRI) study had disclosed a C4-C5 intramedullary lesion. On admission to our Department, the patient had a nearly complete tetraparesis...
June 2006: Journal of Neurosurgical Sciences
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