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Mechanical ventilation, shock, cardiac arrest

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https://www.readbyqxmd.com/read/27749762/infectious-complications-and-immune-inflammatory-response-in-cardiogenic-shock-patients-a-prospective-observational-study
#1
Jiri Parenica, Jiri Jarkovsky, Jan Malaska, Alexandre Mebazaa, Jana Gottwaldova, Katerina Helanova, Jiri Litzman, Milan Dastych, Josef Tomandl, Jindrich Spinar, Ludmila Dostalova, Petr Lokaj, Marie Tomandlova, Monika Goldergova Pavkova, Pavel Sevcik, Matthieu Legrand
INTRODUCTION: Cardiogenic shock (CS) patients are at a high risk of developing infectious complications; however, their early detection is difficult, mainly due to a frequently occurring non-infectious inflammatory response, which accompanies an extensive myocardial infarction or a post-cardiac arrest syndrome. The goal of our prospective study was to describe infectious complications in CS and the immune/inflammatory response based on a serial measurement of several blood-based inflammatory biomarkers...
September 29, 2016: Shock
https://www.readbyqxmd.com/read/27659881/coronary-angiography-after-cardiac-arrest-rationale-and-design-of-the-coact-trial
#2
Jorrit S Lemkes, Gladys N Janssens, Heleen M Oudemans-van Straaten, Paul W Elbers, Nina W van der Hoeven, Jan G P Tijssen, Luuk C Otterspoor, Michiel Voskuil, Joris J van der Heijden, Martijn Meuwissen, Tom A Rijpstra, Georgios J Vlachojannis, Raoul M van der Vleugel, Koen Nieman, Lucia S D Jewbali, Gabe B Bleeker, Rémon Baak, Bert Beishuizen, Martin G Stoel, Pim van der Harst, Cyril Camaro, José P S Henriques, Maarten A Vink, Marcel T M Gosselink, Hans A Bosker, Harry J G M Crijns, Niels van Royen
BACKGROUND: Ischemic heart disease is a major cause of out-of-hospital cardiac arrest. The role of immediate coronary angiography (CAG) and percutaneous coronary intervention (PCI) after restoration of spontaneous circulation following cardiac arrest in the absence of ST-segment elevation myocardial infarction (STEMI) remains debated. HYPOTHESIS: We hypothesize that immediate CAG and PCI, if indicated, will improve 90-day survival in post-cardiac arrest patients without signs of STEMI...
October 2016: American Heart Journal
https://www.readbyqxmd.com/read/27501853/pilot-trial-of-intravenous-lipid-emulsion-treatment-for-severe-nifedipine-induced-shock
#3
Christine M Murphy, Cliff Williams, Michael E Quinn, Brian Nicholson, Thomas Shoe, Michael C Beuhler, William P Kerns
Animal studies and human case reports show promise in using lipid rescue to treat refractory calcium channel antagonist toxicity. However, the majority of research and clinical experience has focused on non-dihydropyridine agents. Thus, we sought to investigate the value of lipid emulsion (ILE) therapy for dihydropyridine-induced shock. This IACUC-approved study utilized seven swine that were sedated with alpha-chloralose, mechanically ventilated, and instrumented for drug delivery and hemodynamic measures...
December 2016: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/27392153/reduction-of-serious-adverse-events-demanding-study-exclusion-in-model-development-extracorporeal-life-support-resuscitation-of-ventricular-fibrillation-cardiac-arrest-in-rats
#4
Alexandra-Maria Warenits, Fritz Sterz, Andreas Schober, Florian Ettl, Ingrid Anna Maria Magnet, Sandra Högler, Ursula Teubenbacher, Daniel Grassmann, Michael Wagner, Andreas Janata, Wolfgang Weihs
Extracorporeal life support is a promising concept for selected patients in refractory cardiogenic shock and for advanced life support of persistent ventricular fibrillation cardiac arrest. Animal models of ventricular fibrillation cardiac arrest could help to investigate new treatment strategies for successful resuscitation. Associated procedural pitfalls in establishing a rat model of extracorporeal life support resuscitation need to be replaced, refined, reduced and reported.Anesthetized male Sprague-Dawley rats (350-600 g), (n = 126), underwent cardiac arrest induced with a pacing catheter placed into the right ventricle via a jugular cannula...
July 7, 2016: Shock
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#5
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27182849/guidelines-for-the-appropriate-use-of-bedside-general-and-cardiac-ultrasonography-in-the-evaluation-of-critically-ill-patients-part-ii-cardiac-ultrasonography
#6
Alexander Levitov, Heidi L Frankel, Michael Blaivas, Andrew W Kirkpatrick, Erik Su, David Evans, Douglas T Summerfield, Anthony Slonim, Raoul Breitkreutz, Susanna Price, Matthew McLaughlin, Paul E Marik, Mahmoud Elbarbary
OBJECTIVE: To establish evidence-based guidelines for the use of bedside cardiac ultrasound, echocardiography, in the ICU and equivalent care sites. METHODS: Grading of Recommendations, Assessment, Development and Evaluation system was used to rank the "levels" of quality of evidence into high (A), moderate (B), or low (C) and to determine the "strength" of recommendations as either strong (strength class 1) or conditional/weak (strength class 2), thus generating six "grades" of recommendations (1A-1B-1C-2A-2B-2C)...
June 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/26927264/cardiac-arrest-during-emergency-cesarean-section-for-severe-pre-eclampsia-and-peripartum-cardiomyopathy
#7
Meng-Han Chou, Hsin-Hui Huang, Yu-Ju Lai, Kwei-Shuai Hwang, Yu-Chi Wang, Her-Young Su
OBJECTIVE: To present the correlation between severe pre-eclampsia and peripartum cardiomyopathy in pregnancy. CASE REPORT: A 41-year-old parturient, gravida 3, para 1, at 34 4/7 weeks' gestation, was diagnosed with severe pre-eclampsia. At the time of admission, a plain chest film disclosed bilateral pleural effusions. An emergent cesarean section was planned because of decreased fetal movement, heavy daily protein loss, and bilateral pleural effusions. During the cesarean section, she developed shock with acute respiratory failure...
February 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26660871/high-degree-atrioventricular-block-complicating-st-segment-elevation-myocardial-infarction-in-the-contemporary-era
#8
Vincent Auffret, Aurélie Loirat, Guillaume Leurent, Raphael P Martins, Emmanuelle Filippi, Isabelle Coudert, Jean Philippe Hacot, Martine Gilard, Philippe Castellant, Antoine Rialan, Régis Delaunay, Gilles Rouault, Philippe Druelles, Bertrand Boulanger, Josiane Treuil, Bertrand Avez, Marc Bedossa, Dominique Boulmier, Marielle Le Guellec, Jean-Claude Daubert, Hervé Le Breton
BACKGROUND: High-degree atrioventricular block (HAVB) is a common complication of ST segment elevation myocardial infarction (STEMI). HAVB in STEMI is historically considered as a marker of worse outcome but overall data about HAVB in the contemporary era of mechanical reperfusion and potent antiplatelet therapies are scarce. AIM: Analysing incidence, clinical correlates and impact on inhospital outcomes of HAVB in a large prospective registry (Observatoire Régional Breton sur l'Infarctus, ORBI) of modern management of STEMI with a special focus on potential differences between patients with HAVB on admission and those who developed HAVB during hospitalisation...
January 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/26541722/resident-participation-in-laparoscopic-roux-en-y-gastric-bypass-a-comparison-of-outcomes-from-the-acs-nsqip-database
#9
Laura Doyon, Alejandro Moreno-Koehler, Rocco Ricciardi, Dmitry Nepomnayshy
BACKGROUND: As clinical outcome data are increasingly tied to hospital reimbursement, balancing quality care with training of surgical residents has become critical. We used the ACS-NSQIP database to determine impact of resident participation in laparoscopic gastric bypass on 30-day morbidity and mortality. METHODS: We queried the ACS-NSQIP database from 1/2005 to 12/2012 for laparoscopic gastric bypass, dividing cases between those with or without resident involvement...
August 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26523008/vasopressors-and-development-of-pressure-ulcers-in-adult-critical-care-patients
#10
Jill Cox, Sharon Roche
BACKGROUND: Vasopressors are lifesaving agents used to raise mean arterial pressure in critically ill patients in shock states. The pharmacodynamics of these agents suggest vasopressors may play a role in development of pressure ulcers; however, this aspect has been understudied. OBJECTIVE: To examine associations between type, dose, and duration of vasopressors (norepinephrine, epinephrine, vasopressin, phenylephrine, dopamine) and development of pressure ulcers in medical-surgical and cardiothoracic intensive care unit patients and to examine predictors of the development of pressure ulcers in these patients...
November 2015: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/26447854/capnography-during-critical-illness
#11
REVIEW
Boulos S Nassar, Gregory A Schmidt
Capnography has made steady inroads in the ICU and is increasingly used for all patients who are mechanically ventilated. There is growing recognition that capnography is rich in information about lung and circulatory physiology and provides insight into many diseases and treatments. These include conditions of impaired matching of ventilation and perfusion, such as pulmonary embolism and obstructive lung diseases; circulatory questions, such as the adequacy of chest compressions during cardiac arrest or fluid responsiveness in patients in shock; and the safety of procedural sedation...
February 2016: Chest
https://www.readbyqxmd.com/read/26365478/transradial-versus-transfemoral-approach-for-percutaneous-coronary-intervention-in-cardiogenic-shock-a-radial-first-centre-experience-and-meta-analysis-of-published-studies
#12
REVIEW
Vincent Roule, Adrien Lemaitre, Rémi Sabatier, Thérèse Lognoné, Ziad Dahdouh, Ludovic Berger, Paul Milliez, Gilles Grollier, Gilles Montalescot, Farzin Beygui
BACKGROUND: The transradial approach for percutaneous coronary intervention (PCI) is associated with a better outcome in myocardial infarction (MI), but patients with cardiogenic shock (CS) were excluded from most trials. AIMS: To compare outcomes of PCI for MI-related CS via the transradial versus transfemoral approach. METHODS: A prospective cohort of 101 consecutive patients admitted for PCI for MI-related CS were treated via the transradial (n=74) or transfemoral (n=27) approach...
November 2015: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/26033984/predicting-survival-after-ecmo-for-refractory-cardiogenic-shock-the-survival-after-veno-arterial-ecmo-save-score
#13
Matthieu Schmidt, Aidan Burrell, Lloyd Roberts, Michael Bailey, Jayne Sheldrake, Peter T Rycus, Carol Hodgson, Carlos Scheinkestel, D Jamie Cooper, Ravi R Thiagarajan, Daniel Brodie, Vincent Pellegrino, David Pilcher
RATIONALE: Extracorporeal membrane oxygenation (ECMO) may provide mechanical pulmonary and circulatory support for patients with cardiogenic shock refractory to conventional medical therapy. Prediction of survival in these patients may assist in management of these patients and comparison of results from different centers. AIMS: To identify pre-ECMO factors which predict survival from refractory cardiogenic shock requiring ECMO and create the survival after veno-arterial-ECMO (SAVE)-score...
September 1, 2015: European Heart Journal
https://www.readbyqxmd.com/read/26002690/diuretic-versus-placebo-in-normotensive-acute-pulmonary-embolism-with-right-ventricular-enlargement-and-injury-a-double-blind-randomised-placebo-controlled-study-protocol-of-the-diper-study
#14
RANDOMIZED CONTROLLED TRIAL
Romain Gallet, Guy Meyer, Julien Ternacle, Caroline Biendel, Anne Brunet, Nicolas Meneveau, Roger Rosario, Francis Couturaud, Mustapha Sebbane, Nicolas Lamblin, Helene Bouvaist, Pierre Coste, Bernard Maitre, Sylvie Bastuji-Garin, Jean-Luc Dubois-Rande, Pascal Lim
INTRODUCTION: In acute pulmonary embolism (PE), poor outcome is usually related to right ventricular (RV) failure due to the increase in RV afterload. Treatment of PE with RV failure without shock is controversial and usually relies on fluid expansion to increase RV preload. However, several studies suggest that fluid expansion may worsen acute RV failure by increasing RV dilation and ischaemia, and increase left ventricular compression by RV dilation. By reducing RV enlargement, diuretic treatment may break this vicious circle and provide early improvement in normotensive patients referred for acute PE with RV failure...
May 22, 2015: BMJ Open
https://www.readbyqxmd.com/read/25938619/a-rat-model-of-ventricular-fibrillation-and-resuscitation-by-conventional-closed-chest-technique
#15
Lorissa Lamoureux, Jeejabai Radhakrishnan, Raúl J Gazmuri
A rat model of electrically-induced ventricular fibrillation followed by cardiac resuscitation using a closed chest technique that incorporates the basic components of cardiopulmonary resuscitation in humans is herein described. The model was developed in 1988 and has been used in approximately 70 peer-reviewed publications examining a myriad of resuscitation aspects including its physiology and pathophysiology, determinants of resuscitability, pharmacologic interventions, and even the effects of cell therapies...
2015: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/25855899/association-between-arterial-hyperoxia-and-outcome-in-subsets-of-critical-illness-a-systematic-review-meta-analysis-and-meta-regression-of-cohort-studies
#16
REVIEW
Hendrik J F Helmerhorst, Marie-José Roos-Blom, David J van Westerloo, Evert de Jonge
OBJECTIVE: Oxygen is vital during critical illness, but hyperoxia may harm patients. Our aim was to systematically evaluate the methodology and findings of cohort studies investigating the effects of hyperoxia in critically ill adults. DATA SOURCE: A meta-analysis and meta-regression analysis of cohort studies published between 2008 and 2015 was conducted. Electronic databases of MEDLINE, EMBASE, and Web of Science were systematically searched for the keywords hyperoxia and mortality or outcome...
July 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/25616319/sulfide-intoxication-induced-circulatory-failure-is-mediated-by-a-depression-in-cardiac-contractility
#17
Takashi Sonobe, Philippe Haouzi
Hydrogen sulfide (H2S) intoxication produces a rapid cardio-circulatory failure leading to cardiac arrest. In non-lethal forms of sulfide exposure, the presence of a circulatory shock is associated with long-term neurological sequelae. Our aim was to clarify the mechanisms of H2S-induced circulatory failure. In anesthetized, paralyzed, and mechanically ventilated rats, cardiac output, arterial pressure and ventricular pressures were determined while NaHS was infused to increase arterial concentration of soluble H2S (CgH2S) from undetectable to levels leading to circulatory failure...
January 2016: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/25449345/resuscitative-extracorporeal-membrane-oxygenation-for-in-hospital-cardiac-arrest-a-canadian-observational-experience
#18
Joseph M Bednarczyk, Christopher W White, Robin A Ducas, Mehrdad Golian, Roman Nepomuceno, Brett Hiebert, Derek Bueddefeld, Rizwan A Manji, Rohit K Singal, Farrukh Hussain, Darren H Freed
BACKGROUND: Among patients with reversible conditions who sustain cardiac arrest, extracorporeal membrane oxygenation (ECMO) may support end organ perfusion while bridging to definitive therapy. METHODS: A single center retrospective review (February 2008–September 2013) of adults receiving ECMO for cardiac arrest ≥15 min duration refractory to conventional management (E-CPR) or profound cardiogenic shock following IHCA (E-CS) was conducted. The primary outcome was 30-day survival with good neurologic function defined as a cerebral performance category (CPC) of 1–2...
December 2014: Resuscitation
https://www.readbyqxmd.com/read/25378961/prognostic-factors-for-death-and-survival-with-or-without-complications-in-cardiac-arrest-patients-receiving-cpr-within-24-hours-of-anesthesia-for-emergency-surgery
#19
Visith Siriphuwanun, Yodying Punjasawadwong, Worawut Lapisatepun, Somrat Charuluxananan, Ketchada Uerpairojkit
PURPOSE: To determine prognostic factors for death and survival with or without complications in cardiac arrest patients who received cardiopulmonary resuscitation (CPR) within 24 hours of receiving anesthesia for emergency surgery. PATIENTS AND METHODS: A retrospective cohort study approved by the Maharaj Nakorn Chiang Mai University Hospital Ethical Committee. Data used were taken from records of 751 cardiac arrest patients who received their first CPR within 24 hours of anesthesia for emergency surgery between January 1, 2003 and October 31, 2011...
2014: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/25313335/incidence-outcome-and-attributable-resource-use-associated-with-pulmonary-and-cardiac-complications-after-major-small-and-large-bowel-procedures
#20
Lee A Fleisher, Walter T Linde-Zwirble
BACKGROUND: Complications increase the costs of care of surgical patients. We studied the Premier database to determine the incidence and direct medical costs related to pulmonary complications and compared it to cardiac complications in the same cohort. METHODS: We identified 45,969 discharges in patients undergoing major bowel procedures. Postoperative pulmonary and cardiac complications were identified through the use of International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes and through the use of daily resource use data...
2014: Perioperative Medicine
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