keyword
MENU ▼
Read by QxMD icon Read
search

Laboratory data prediction models

keyword
https://www.readbyqxmd.com/read/29137627/prevalence-of-current-patterns-and-predictive-trends-of-multidrug-resistant-salmonella-typhi-in-sudan
#1
Ayman A Elshayeb, Abdelazim A Ahmed, Marmar A El Siddig, Adil A El Hussien
BACKGROUND: Enteric fever has persistence of great impact in Sudanese public health especially during rainy season when the causative agent Salmonella enterica serovar Typhi possesses pan endemic patterns in most regions of Sudan - Khartoum. OBJECTIVES: The present study aims to assess the recent state of antibiotics susceptibility of Salmonella Typhi with special concern to multidrug resistance strains and predict the emergence of new resistant patterns and outbreaks...
November 14, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29137601/random-walks-on-mutual-microrna-target-gene-interaction-network-improve-the-prediction-of-disease-associated-micrornas
#2
Duc-Hau Le, Lieven Verbeke, Le Hoang Son, Dinh-Toi Chu, Van-Huy Pham
BACKGROUND: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miRNAs in silico. Homogeneous networks (in which every node is a miRNA) based on the targets shared between miRNAs have been widely used to predict their role in disease phenotypes. Although such homogeneous networks can predict potential disease-associated miRNAs, they do not consider the roles of the target genes of the miRNAs...
November 14, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29136443/derivation-and-external-validation-of-prediction-models-for-advanced-chronic-kidney-disease-following-acute-kidney-injury
#3
Matthew T James, Neesh Pannu, Brenda R Hemmelgarn, Peter C Austin, Zhi Tan, Eric McArthur, Braden J Manns, Marcello Tonelli, Ron Wald, Robert R Quinn, Pietro Ravani, Amit X Garg
Importance: Some patients will develop chronic kidney disease after a hospitalization with acute kidney injury; however, no risk-prediction tools have been developed to identify high-risk patients requiring follow-up. Objective: To derive and validate predictive models for progression of acute kidney injury to advanced chronic kidney disease. Design, Setting, and Participants: Data from 2 population-based cohorts of patients with a prehospitalization estimated glomerular filtration rate (eGFR) of more than 45 mL/min/1...
November 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29135657/adapted-sojourn-models-to-estimate-activity-intensity-in-youth-a-suite-of-tools
#4
Paul R Hibbing, Laura D Ellingson, Philip M Dixon, Gregory J Welk
The challenges of using physical activity data from accelerometers have been compounded with the recent focus on wrist-worn monitors and raw acceleration (as opposed to activity counts). PURPOSE: This study developed and systematically evaluated a suite of new accelerometer processing models for youth. METHODS: Four adaptations of the Sojourn method were developed using data from a laboratory-based experiment in which youth (N = 54) performed structured activity routines...
November 10, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29132626/early-hospital-mortality-prediction-of-intensive-care-unit-patients-using-an-ensemble-learning-approach
#5
Aya Awad, Mohamed Bader-El-Den, James McNicholas, Jim Briggs
BACKGROUND: Mortality prediction of hospitalized patients is an important problem. Over the past few decades, several severity scoring systems and machine learning mortality prediction models have been developed for predicting hospital mortality. By contrast, early mortality prediction for intensive care unit patients remains an open challenge. Most research has focused on severity of illness scoring systems or data mining (DM) models designed for risk estimation at least 24 or 48h after ICU admission...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29127832/uranium-in-groundwater-a-synopsis-based-on-a-large-hydrogeochemical-data-set
#6
Thomas Riedel, Christine Kübeck
Most of the knowledge on the occurrence of Uranium (U) in groundwater comes from in-situ manipulation experiments in the field, computational modelling studies or from laboratory analyses where individual processes of U mobilization were studied in isolation. Because of Uranium's vital redox chemistry it interacts, often simultaneously, with many other element cycles (e.g., sulfur, carbon, iron, and manganese) making it difficult to predict U concentrations in natural environments. For the present study a large data set was analyzed to predict the occurrence of U in groundwater from basic hydrochemistry...
November 2, 2017: Water Research
https://www.readbyqxmd.com/read/29127278/the-north-american-bullfrog-draft-genome-provides-insight-into-hormonal-regulation-of-long-noncoding-rna
#7
S Austin Hammond, René L Warren, Benjamin P Vandervalk, Erdi Kucuk, Hamza Khan, Ewan A Gibb, Pawan Pandoh, Heather Kirk, Yongjun Zhao, Martin Jones, Andrew J Mungall, Robin Coope, Stephen Pleasance, Richard A Moore, Robert A Holt, Jessica M Round, Sara Ohora, Branden V Walle, Nik Veldhoen, Caren C Helbing, Inanc Birol
Frogs play important ecological roles, and several species are important model organisms for scientific research. The globally distributed Ranidae (true frogs) are the largest frog family, and have substantial evolutionary distance from the model laboratory Xenopus frog species. Unfortunately, there are currently no genomic resources for the former, important group of amphibians. More widely applicable amphibian genomic data is urgently needed as more than two-thirds of known species are currently threatened or are undergoing population declines...
November 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/29122201/factors-determining-workers-pace-while-conducting-continuous-sequential-lifting-carrying-and-lowering-tasks
#8
Yaar Harari, Raziel Riemer, Avital Bechar
To plan a new manual material handling work process, it is necessary to predict the times required to complete each task. Current time prediction models lack validity when the handled object's mass exceeds 2 kg. In this study, we investigated the effect of workplace design parameters on continuous sequential lifting, carrying, and lowering of boxes weighing from 2 kg to 14 kg. Both laboratory and field experiments were conducted. Results revealed that the box's weight and the lifting and lowering heights influenced the tasks' times...
February 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29119514/systems-biology-driven-hypotheses-tested-in-vivo-the-need-to-advancing-molecular-imaging-tools
#9
Garima Verma, Alessandro Palombo, Mauro Grigioni, Morena La Monaca, Giuseppe D'Avenio
Processing and interpretation of biological images may provide invaluable insights on complex, living systems because images capture the overall dynamics as a "whole." Therefore, "extraction" of key, quantitative morphological parameters could be, at least in principle, helpful in building a reliable systems biology approach in understanding living objects. Molecular imaging tools for system biology models have attained widespread usage in modern experimental laboratories. Here, we provide an overview on advances in the computational technology and different instrumentations focused on molecular image processing and analysis...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29116006/analysis-of-near-infrared-spectra-for-age-grading-of-wild-populations-of-anopheles-gambiae
#10
Benjamin J Krajacich, Jacob I Meyers, Haoues Alout, Roch K Dabiré, Floyd E Dowell, Brian D Foy
BACKGROUND: Understanding the age-structure of mosquito populations, especially malaria vectors such as Anopheles gambiae, is important for assessing the risk of infectious mosquitoes, and how vector control interventions may impact this risk. The use of near-infrared spectroscopy (NIRS) for age-grading has been demonstrated previously on laboratory and semi-field mosquitoes, but to date has not been utilized on wild-caught mosquitoes whose age is externally validated via parity status or parasite infection stage...
November 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29115910/factors-associated-with-long-turnaround-time-for-early-infant-diagnosis-of-hiv-in-myanmar
#11
Soe Thiha, Hemant Deepak Shewade, Sairu Philip, Thet Ko Aung, Nang Thu Thu Kyaw, Myo Minn Oo, Khine Wut Yee Kyaw, May Wint War, Htun Nyunt Oo
BACKGROUND: A previous review of early infant diagnosis (EID) using polymerase chain reaction technology (PCR) under integrated HIV care (IHC) program in Myanmar revealed a low uptake of timely (within 6 to 8 weeks of babies' age) EID and a long turnaround time (TAT) of receiving results. OBJECTIVE: This study aimed to determine the proportion and factors associated with the composite outcome of a long TAT (≥7 weeks; from sample collection to receipt of result by mother) or nonreceipt of result among HIV-exposed babies whose blood samples were collected for PCR at <9 months of age under the IHC program, Myanmar (2013-15)...
2017: Global Health Action
https://www.readbyqxmd.com/read/29112958/cardiovascular-disease-cvd-and-chronic-kidney-disease-ckd-event-rates-in-hiv-positive-persons-at-high-predicted-cvd-and-ckd-risk-a-prospective-analysis-of-the-d-a-d-observational-study
#12
Mark A Boyd, Amanda Mocroft, Lene Ryom, Antonella d'Arminio Monforte, Caroline Sabin, Wafaa M El-Sadr, Camilla Ingrid Hatleberg, Stephane De Wit, Rainer Weber, Eric Fontas, Andrew Phillips, Fabrice Bonnet, Peter Reiss, Jens Lundgren, Matthew Law
BACKGROUND: The Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study has developed predictive risk scores for cardiovascular disease (CVD) and chronic kidney disease (CKD, defined as confirmed estimated glomerular filtration rate [eGFR] ≤ 60 ml/min/1.73 m2) events in HIV-positive people. We hypothesized that participants in D:A:D at high (>5%) predicted risk for both CVD and CKD would be at even greater risk for CVD and CKD events. METHODS AND FINDINGS: We included all participants with complete risk factor (covariate) data, baseline eGFR > 60 ml/min/1...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29112839/environmental-fate-of-amine-oxide-using-measured-and-predicted-values-to-determine-aquatic-exposure
#13
Kathleen McDonough, Nina Itrich, Jennifer Menzies, Kenneth Casteel, Scott Belanger, Kenneth Wehmeyer
Amine oxide (AO) surfactants are used widely in North American household detergents resulting in >44,000mtons disposed down the drain annually. Due to AOs substantial down the drain disposal volume, wide dispersive use, and high aquatic toxicity, there is a need to evaluate ecological exposure and corresponding risk. This study refined the current knowledge regarding the fate of AO disposed down the drain through laboratory simulation studies to evaluate biodegradation in the sewer and during activated sludge wastewater treatment...
November 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29112827/incremental-validity-of-estimated-cannabis-grams-as-a-predictor-of-problems-and-cannabinoid-biomarkers-evidence-from-a-clinical-trial
#14
Rachel L Tomko, Nathaniel L Baker, Erin A McClure, Susan C Sonne, Aimee L McRae-Clark, Brian J Sherman, Kevin M Gray
BACKGROUND: Quantifying cannabis use is complex due to a lack of a standardized packaging system that contains specified amounts of constituents. A laboratory procedure has been developed for estimating physical quantity of cannabis use by utilizing a surrogate substance to represent cannabis, and weighing the amount of the surrogate to determine typical use in grams. METHOD: This secondary analysis utilized data from a multi-site, randomized, controlled pharmacological trial for adult cannabis use disorder (N=300), sponsored by the National Drug Abuse Treatment Clinical Trials Network, to test the incremental validity of this procedure...
November 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29111599/experimental-investigation-of-alternative-transmission-functions-quantitative-evidence-for-the-importance-of-non-linear-transmission-dynamics-in-host-parasite-systems
#15
Sarah A Orlofske, Samuel M Flaxman, Maxwell B Joseph, Andy Fenton, Brett A Melbourne, Pieter T J Johnson
1.Understanding pathogen transmission is crucial for predicting and managing disease. Nonetheless, experimental comparisons of alternative functional forms of transmission remain rare, and those experiments that are conducted are often not designed to test the full range of possible forms. 2.To differentiate among ten candidate transmission functions, we used a novel experimental design in which we independently varied four factors-duration of exposure, numbers of parasites, numbers of hosts, and parasite density-in laboratory infection experiments...
November 7, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/29110697/exutr-a-novel-pipeline-for-large-scale-prediction-of-3-utr-sequences-from-ngs-data
#16
Zixia Huang, Emma C Teeling
BACKGROUND: The three prime untranslated region (3'-UTR) is known to play a pivotal role in modulating gene expression by determining the fate of mRNA. Many crucial developmental events, such as mammalian spermatogenesis, tissue patterning, sex determination and neurogenesis, rely heavily on post-transcriptional regulation by the 3'-UTR. However, 3'-UTR biology seems to be a relatively untapped field, with only limited tools and 3'-UTR resources available. To elucidate the regulatory mechanisms of the 3'-UTR on gene expression, firstly the 3'-UTR sequences must be identified...
November 6, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29110580/clinical-significance-of-low-2-methoxyestradiol-levels-in-serum-and-tissue-of-recurrent-juvenile-onset-laryngeal-papillomatosis
#17
Danling Liu, Jiadong Wang, Yanan Xu
Objective We aim to explore the correlation between serum and tissue 2-methoxyestradiol (2-ME-2) levels and recurrence of juvenile-onset respiratory papillomatosis (JORRP). Study Design Retrospective cohort studies. Settings Laboratory of Otolaryngology, Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University. Subjects and Methods Sixty-four patients diagnosed with JORRP in our department from January 2007 to December 2012 were enrolled. Patients were divided into recurrence and nonrecurrence groups, with 32 patients in each group...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29110234/soil-ecological-criteria-for-nickel-as-a-function-of-soil-properties
#18
XiaoQing Wang, DongPu Wei, YiBing Ma, Mike J McLaughlin
Scientific information for the chemistry and ecotoxicology of metals in soils has been obtained in the research conducted in recent years. However, the latest "science" obtained from this research has not yet been translated into "regulations" in China. In the present study, the predicted no effect concentrations (PNECs) for Ni which denoted as soil ecological criteria for Ni were derived based on the effects of soil properties on bioavailability/ecotoxicity of Ni, incorporating the differences in species sensitivity as well as in laboratory and field conditions...
November 6, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29109379/development-of-a-shipboard-remote-control-and-telemetry-experimental-system-for-large-scale-model-s-motions-and-loads-measurement-in-realistic-sea-waves
#19
Jialong Jiao, Huilong Ren, Christiaan Adika Adenya, Chaohe Chen
Wave-induced motion and load responses are important criteria for ship performance evaluation. Physical experiments have long been an indispensable tool in the predictions of ship's navigation state, speed, motions, accelerations, sectional loads and wave impact pressure. Currently, majority of the experiments are conducted in laboratory tank environment, where the wave environments are different from the realistic sea waves. In this paper, a laboratory tank testing system for ship motions and loads measurement is reviewed and reported first...
October 29, 2017: Sensors
https://www.readbyqxmd.com/read/29108017/assessing-risk-of-fibrosis-progression-and-liver-related-clinical-outcomes-among-patients-with-both-early-stage-and-advanced-chronic-hepatitis-c
#20
Monica A Konerman, Dongxia Lu, Yiwei Zhang, Mary Thomson, Ji Zhu, Aashesh Verma, Boang Liu, Nizar Talaat, Ulysses Balis, Peter D R Higgins, Anna S F Lok, Akbar K Waljee
OBJECTIVE: Assessing risk of adverse outcomes among patients with chronic liver disease has been challenging due to non-linear disease progression. We previously developed accurate prediction models for fibrosis progression and clinical outcomes among patients with advanced chronic hepatitis C (CHC). The primary aim of this study was to validate fibrosis progression and clinical outcomes models among a heterogeneous patient cohort. DESIGN: Adults with CHC with ≥3 years follow-up and without hepatic decompensation, hepatocellular carcinoma (HCC), liver transplant (LT), HBV or HIV co-infection at presentation were analyzed (N = 1007)...
2017: PloS One
keyword
keyword
81410
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"