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Laboratory data prediction models

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https://www.readbyqxmd.com/read/28334271/a-temperature-dependent-phenology-model-for-liriomyza-huidobrensis-diptera-agromyzidae
#1
Norma Mujica, Marc Sporleder, Pablo Carhuapoma, Jürgen Kroschel
Liriomyza huidobrensis (Blanchard) is an economically important and highly polyphagous worldwide pest. To establish a temperature-dependent phenology model, essential for understanding the development and growth of the pest population under a variety of climates and as part of a pest risk analysis, L. huidobrensis life-table data were collected under laboratory conditions at seven constant temperatures on its host faba bean (Vicia faba L.). Several nonlinear equations were fitted to each life stage to model the temperature-dependent population growth and species life history and finally compile an overall temperature-dependent pest phenology model using the Insect Life Cycle Modeling (ILCYM) software...
March 8, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28331548/discovering-feature-relevancy-and-dependency-by-kernel-guided-probabilistic-model-building-evolution
#2
Nestor Rodriguez, Sergio Rojas-Galeano
BACKGROUND: Discovering relevant features (biomarkers) that discriminate etiologies of a disease is useful to provide biomedical researchers with candidate targets for further laboratory experimentation while saving costs; dependencies among biomarkers may suggest additional valuable information, for example, to characterize complex epistatic relationships from genetic data. The use of classifiers to guide the search for biomarkers (the so-called wrapper approach) has been widely studied...
2017: BioData Mining
https://www.readbyqxmd.com/read/28329027/prevalence-and-predictors-for-compensated-advanced-chronic-liver-disease-c-acld-in-patients-with-chronic-hepatitis-delta-virus-hdv-infection
#3
Ingrid Couto, Marilu Victoria, Valdiléa G Veloso, Lorena Rodrigues, Beatriz Grinsztejn, Marcus Lacerda, Flamir Victoria, Hugo Perazzo
OBJECTIVE: The study aimed to evaluate the prevalence and predictor factors for compensated advanced chronic liver disease (c-ACLD) in patients with hepatitis Delta virus (HDV) infection. METHODS: This cross-sectional study included consecutive HDV-infected patients defined by positive anti-HDV. Patients with hepatitis C coinfection, liver transplantation or presence of conditions that limit liver (LSM) or spleen stiffness measurement (SSM) were excluded. Blood tests, abdominal ultrasound, SSM and LSM by transient elastography (FibroScan®) were performed at the same day...
2017: PloS One
https://www.readbyqxmd.com/read/28329014/prediction-of-chronic-damage-in-systemic-lupus-erythematosus-by-using-machine-learning-models
#4
Fulvia Ceccarelli, Marco Sciandrone, Carlo Perricone, Giulio Galvan, Francesco Morelli, Luis Nunes Vicente, Ilaria Leccese, Laura Massaro, Enrica Cipriano, Francesca Romana Spinelli, Cristiano Alessandri, Guido Valesini, Fabrizio Conti
OBJECTIVE: The increased survival in Systemic Lupus Erythematosus (SLE) patients implies the development of chronic damage, occurring in up to 50% of cases. Its prevention is a major goal in the SLE management. We aimed at predicting chronic damage in a large monocentric SLE cohort by using neural networks. METHODS: We enrolled 413 SLE patients (M/F 30/383; mean age ± SD 46.3±11.9 years; mean disease duration ± SD 174.6 ± 112.1 months). Chronic damage was assessed by the SLICC/ACR Damage Index (SDI)...
2017: PloS One
https://www.readbyqxmd.com/read/28328838/development-and-validation-of-a-risk-prediction-nomogram-for-in-hospital-mortality-in-adults-poisoned-with-drugs-and-nonpharmaceutical-agents-an-observational-study
#5
Catalina Lionte, Victorita Sorodoc, Elisabeta Jaba, Alina Botezat
Acute poisoning with drugs and nonpharmaceutical agents represents an important challenge in the emergency department (ED).The objective is to create and validate a risk-prediction nomogram for use in the ED to predict the risk of in-hospital mortality in adults from acute poisoning with drugs and nonpharmaceutical agents.This was a prospective cohort study involving adults with acute poisoning from drugs and nonpharmaceutical agents admitted to a tertiary referral center for toxicology between January and December 2015 (derivation cohort) and between January and June 2016 (validation cohort)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328623/a-novel-user-friendly-model-to-predict-corticosteroid-utilization-in-newly-diagnosed-patients-with-ulcerative-colitis
#6
Nabeel Khan, Dhruvan Patel, Yash Shah, Gary Lichtenstein, Yu-Xiao Yang
BACKGROUND: Corticosteroid (CS) use is an important marker of poor prognosis in ulcerative colitis (UC). Our aim was to develop and validate a model to predict the risk of CS utilization over the course of disease in newly diagnosed patients with UC. METHODS: Newly diagnosed patients with UC from a nationwide VA cohort were followed over time to evaluate factors predictive of CS use. Multivariate logistic regression was performed. Model development was performed in a random 2/3 of the total cohort and then validated in the remaining 1/3...
March 21, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28319762/growth-of-algal-biomass-in-laboratory-and-in-large-scale-algal-photobioreactors-in-the-temperate-climate-of-western-germany
#7
Christina Schreiber, Dominik Behrendt, Gregor Huber, Christian Pfaff, Janka Widzgowski, Bärbel Ackermann, Andreas Müller, Vilém Zachleder, Šárka Moudříková, Peter Mojzeš, Ulrich Schurr, Johan Grobbelaar, Ladislav Nedbal
Growth of Chlorella vulgaris was characterized as a function of irradiance in a laboratory turbidostat (1L) and compared to batch growth in sunlit modules (5-25L) of the commercial NOVAgreen photobioreactor. The effects of variable sunlight and culture density were deconvoluted by a mathematical model. The analysis showed that algal growth was light-limited due to shading by external construction elements and due to light attenuation within the algal bags. The model was also used to predict maximum biomass productivity...
March 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28318698/stochastic-modeling-of-phosphorus-transport-in-the-three-gorges-reservoir-by-incorporating-variability-associated-with-the-phosphorus-partition-coefficient
#8
Lei Huang, Hongwei Fang, Xingya Xu, Guojian He, Xuesong Zhang, Danny Reible
Phosphorus (P) fate and transport plays a crucial role in the ecology of rivers and reservoirs in which eutrophication is limited by P. A key uncertainty in models used to help manage P in such systems is the partitioning of P to suspended and bed sediments. By analyzing data from field and laboratory experiments, we stochastically characterize the variability of the partition coefficient (Kd) and derive spatio-temporal solutions for P transport in the Three Gorges Reservoir (TGR). We formulate a set of stochastic partial different equations (SPDEs) to simulate P transport by randomly sampling Kd from the measured distributions, to obtain statistical descriptions of the P concentration and retention in the TGR...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28314596/on-treatment-hbv-dna-level-could-predict-hbeag-seroclearance-in-patients-with-hbeag-positive-chronic-hepatitis-b-with-entecavir-therapy
#9
Yi-Jie Huang, Chi-Sen Chang, Yen-Chun Peng, Hong-Zen Yeh, Sheng-Shun Yang
BACKGROUND: Hepatitis B e antigen (HBeAg) status is associated with clinical outcomes, and seroconversion of HBeAg is one of the treatment goals. In this study, we determined the association of on-treatment serum hepatitis B virus (HBV) DNA levels in HBeAg-positive chronic hepatitis B patients who were receiving entecavir (ETV) treatment. METHODS: A retrospective cohort study was conducted involving 135 (78 male and 57 female; mean age, 42.3 ± 13 years) patients with HBeAg-positive chronic hepatitis B (CHB)...
March 14, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28301564/temperature-dependent-phenology-of-plutella-xylostella-lepidoptera-plutellidae-simulation-and-visualization-of-current-and-future-distributions-along-the-eastern-afromontane
#10
Benignus V Ngowi, Henri E Z Tonnang, Evans M Mwangi, Tino Johansson, Janet Ambale, Paul N Ndegwa, Sevgan Subramanian
There is a scarcity of laboratory and field-based results showing the movement of the diamondback moth (DBM) Plutella xylostella (L.) across a spatial scale. We studied the population growth of the diamondback moth (DBM) Plutella xylostella (L.) under six constant temperatures, to understand and predict population changes along altitudinal gradients and under climate change scenarios. Non-linear functions were fitted to continuously model DBM development, mortality, longevity and oviposition. We compiled the best-fitted functions for each life stage to yield a phenology model, which we stochastically simulated to estimate the life table parameters...
2017: PloS One
https://www.readbyqxmd.com/read/28291474/the-development-of-a-probabilistic-dose-response-for-a-burn-injury-model
#11
Anthony Iyoho, Laurel Ng, Philemon Chan
OBJECTIVE: The objective was to augment a burn injury model, BURNSIM, with probabilistic dose-response risk curves. METHODS: To develop the dose-response, we drew on a considerable amount of historical porcine burn injury data collected by U.S. Army Aeromedical Research Laboratory in the 1970s. The experimental parameters of each usable data point served as inputs to BURNSIM to calculate the burn damage integral (i.e., the internal dose) for 4 severities (mild, intermediate, deep second- and third-degree burns)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290264/malnutrition-is-associated-with-increased-mortality-in-older-adults-regardless-of-the-cause-of-death
#12
Lisa Söderström, Andreas Rosenblad, Eva Thors Adolfsson, Leif Bergkvist
Malnutrition predicts preterm death, but whether this is valid irrespective of the cause of death is unknown. The aim of the present study was to determine whether malnutrition is associated with cause-specific mortality in older adults. This cohort study was conducted in Sweden and included 1767 individuals aged ≥65 years admitted to hospital in 2008-2009. On the basis of the Mini Nutritional Assessment instrument, nutritional risk was assessed as well nourished (score 24-30), at risk of malnutrition (score 17-23·5) or malnourished (score <17)...
March 14, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28289557/acoustic-monitoring-indicates-a-correlation-between-calling-and-spawning-in-captive-spotted-seatrout-cynoscion-nebulosus
#13
Eric W Montie, Matt Hoover, Christopher Kehrer, Justin Yost, Karl Brenkert, Tim O'Donnell, Michael R Denson
BACKGROUND: Fish sound production is widespread throughout many families. Territorial displays and courtship are the most common reasons for fish sound production. Yet, there is still some questions on how acoustic signaling and reproduction are correlated in many sound-producing species. In the present study, our aim was to determine if a quantitative relationship exists between calling and egg deposition in captive spotted seatrout (Cynoscion nebulosus). This type of data is essential if passive acoustics is to be used to identify spawning aggregations over large spatial scales and monitor reproductive activity over annual and decadal timeframes...
2017: PeerJ
https://www.readbyqxmd.com/read/28289541/case-series-of-fournier-s-gangrene-affected-body-surface-area-the-underestimated-prognostic-factor
#14
Henrique Morais, Jessica Neves, Hugo Maciel Ribeiro, Marta Ferreira, Narcisa Guimarães, Nuno Azenha, Raquel Dias, Alice Fonseca, Lucilia Conceição
OBJECTIVES: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015...
April 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28289289/evidence-for-a-fe-3-rich-pyrolitic-lower-mantle-from-al-fe-bearing-bridgmanite-elasticity-data
#15
A Kurnosov, H Marquardt, D J Frost, T Boffa Ballaran, L Ziberna
The chemical composition of Earth's lower mantle can be constrained by combining seismological observations with mineral physics elasticity measurements. However, the lack of laboratory data for Earth's most abundant mineral, (Mg,Fe,Al)(Al,Fe,Si)O3 bridgmanite (also known as silicate perovskite), has hampered any conclusive result. Here we report single-crystal elasticity data on (Al,Fe)-bearing bridgmanite (Mg0.9Fe0.1Si0.9Al0.1)O3 measured using high-pressure Brillouin spectroscopy and X-ray diffraction. Our measurements show that the elastic behaviour of (Al,Fe)-bearing bridgmanite is markedly different from the behaviour of the MgSiO3 endmember...
March 13, 2017: Nature
https://www.readbyqxmd.com/read/28287315/near-infrared-spectroscopy-and-geostatistical-analysis-for-modeling-spatial-distribution-of-analytical-constituents-in-bulk-animal-by-product-protein-meals
#16
José A Adame-Siles, Tom Fearn, José E Guerrero-Ginel, Ana Garrido-Varo, Francisco Maroto-Molina, Dolores Pérez-Marín
Control and inspection operations within the context of safety and quality assessment of bulk foods and feeds are not only of particular importance, they are also demanding challenges, given the complexity of food/feed production systems and the variability of product properties. Existing methodologies have a variety of limitations, such as high costs of implementation per sample or shortcomings in early detection of potential threats for human/animal health or quality deviations. Therefore, new proposals are required for the analysis of raw materials in situ in a more efficient and cost-effective manner...
March 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28285428/a-novel-model-for-predicting-incident-moderate-to-severe-anemia-and-iron-deficiency-in-patients-with-newly-diagnosed-ulcerative-colitis
#17
Nabeel Khan, Dhruvan Patel, Yash Shah, Yu-Xiao Yang
BACKGROUND: Anemia and iron deficiency are common complications of ulcerative colitis (UC). We aimed to develop and internally validate a prediction model for the incidence of moderate to severe anemia and iron deficiency anemia (IDA) in newly diagnosed patients with UC. METHODS: Multivariable logistic regression was performed among a nationwide cohort of patients who were newly diagnosed with UC in the VA health-care system. Model development was performed in a random two-third of the total cohort and then validated in the remaining one-third of the cohort...
March 11, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28280695/cardiovascular-disease-risk-factors-and-applicability-of-a-risk-model-in-a-greek-cohort-of-renal-transplant-recipients
#18
Nikolaos-Andreas Anastasopoulos, Evangelia Dounousi, Evangelos Papachristou, Charalampos Pappas, Eleni Leontaridou, Eirini Savvidaki, Dimitrios Goumenos, Michael Mitsis
AIM: To investigate the incidence and the determinants of cardiovascular morbidity in Greek renal transplant recipients (RTRs) expressed as major advance cardiac event (MACE) rate. METHODS: Two hundred and forty-two adult patients with a functioning graft for at least three months and available data that were followed up on the August 31, 2015 at two transplant centers of Western Greece were included in this study. Baseline recipients' data elements included demographics, clinical characteristics, history of comorbid conditions and laboratory parameters...
February 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28274560/antithrombin-iii-is-associated-with-acute-liver-failure-in-patients-with-end-stage-heart-failure-undergoing-mechanical-circulatory-support
#19
Judith Hoefer, Hanno Ulmer, Juliane Kilo, Raimund Margreiter, Michael Grimm, Peter Mair, Elfriede Ruttmann
OBJECTIVE: There are few data on the role of liver dysfunction in patients with end-stage heart failure supported by mechanical circulatory support. The aim of our study was to investigate predictors for acute liver failure in patients with end-stage heart failure undergoing mechanical circulatory support. METHODS: A consecutive 164 patients with heart failure with New York Heart Association class IV undergoing mechanical circulatory support were investigated for acute liver failure using the King's College criteria...
February 9, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28273358/estimating-thermal-performance-curves-from-repeated-field-observations
#20
Evan S Childress, Benjamin H Letcher
Estimating thermal performance of organisms is critical for understanding population distributions and dynamics and predicting responses to climate change. Typically, performance curves are estimated using laboratory studies to isolate temperature effects, but other abiotic and biotic factors influence temperature-performance relationships in nature reducing these models' predictive ability. We present a model for estimating thermal performance curves from repeated field observations that includes environmental and individual variation...
March 8, 2017: Ecology
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