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https://www.readbyqxmd.com/read/28149979/a-look-at-the-burden-of-opioid-management-in-primary-care
#1
Morteza Khodaee, Brandy Deffenbacher
PURPOSE: Pain management with opioids in primary care is challenging. The objective of this study was to identify the number of opioid-related tasks in our clinics and determine whether opioid-related tasks occur more often in a residency setting. METHODS: This was a retrospective observational review of an electronic health record (EHR) system to evaluate tasks related to the use of opioids and other controlled substances. Tasks are created in the EHR when patients call the clinic; the task-box system is a means of communication within the EHR...
December 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/28139535/natural-menopause-among-women-below-50-years-in-india-a-population-based-study
#2
Saseendran Pallikadavath, Reuben Ogollah, Abhishek Singh, Tara Dean, Ann Dewey, William Stones
BACKGROUND & OBJECTIVES: The age at which menopause naturally occurs may reflect nutritional and environmental circumstances as well as genetic factors. In this study we examined natural menopause as a marker of women's health at the population level in India and in some major States. METHODS: Data from the Indian District Level Household Survey (DLHS) carried out during 2007-2008 covering 643,944 ever-married women aged 15-49 yr were used; women of older ages were not included in this survey...
September 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28138923/-it-was-an-emotional-baby-previvors-family-planning-decision-making-styles-about-hereditary-breast-and-ovarian-cancer-risk
#3
Marleah Dean, Emily A Rauscher
Women who test positive for a BRCA genetic mutation are at an increased risk for developing hereditary breast and ovarian cancer and have a 50% chance of passing on their genetic mutation to their children. The purpose of this study was to investigate how women who test positive for a BRCA mutation but have not been diagnosed with cancer make decisions regarding family planning. Analysis of interviews with 20 women revealed they engage in logical and emotional decision-making styles. Although women want to be logical to reduce their hereditary cancer risk, emotions often complicate their decision-making...
January 30, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28097748/schinortriterpenoids-a-case-study-in-synthetic-design
#4
REVIEW
Xin Li, Paul Ha-Yeon Cheong, Rich G Carter
Since the pioneering days of total synthesis and retrosynthetic analysis, the community has embraced guiding principles for planning synthetic approaches towards complex natural products. These guideposts have enabled the community to synthesize ever more complex compounds by applying prior knowledge gained in new settings. The recently isolated schinortriterpenoid family of natural products has attracted considerable synthetic attention and provided a rich opportunity to evaluate the lessons learned in the construction of complex, polycyclic scaffolds...
January 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28093642/the-ethical-framework-for-performing-research-with-rare-inherited-neurometabolic-disease-patients
#5
Viviana Giannuzzi, Hugo Devlieger, Lucia Margari, Viveca Lena Odlind, Lamis Ragab, Cinzia Maria Bellettato, Francesca D'Avanzo, Christina Lampe, Linda Cassis, Elisenda Cortès-Saladelafont, Ángels Garcia Cazorla, Ivo Barić, Ljerka Cvitanović-Šojat, Ksenija Fumić, Christine I Dali, Franco Bartoloni, Fedele Bonifazi, Maurizio Scarpa, Adriana Ceci
: The need for performing clinical trials to develop well-studied and appropriate medicines for inherited neurometabolic disease patients faces ethical concerns mainly raising from four aspects: the diseases are rare; include young and very young patients; the neurological impairment may compromise the capability to provide 'consent'; and the genetic nature of the disease leads to further ethical implications. This work is intended to identify the ethical provisions applicable to clinical research involving these patients and to evaluate if these cover the ethical issues...
January 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28086869/evaluation-of-an-aged-care-nurse-practitioner-service-quality-of-care-within-a-residential-aged-care-facility-hospital-avoidance-service
#6
Trudy Dwyer, Alison Craswell, Dolene Rossi, Darren Holzberger
BACKGROUND: Reducing avoidable hospitialisation of aged care facility (ACF) residents can improve the resident experience and their health outcomes. Consequently many variations of hospital avoidance (HA) programs continue to evolve. Nurse practitioners (NP) with expertise in aged care have the potential to make a unique contribution to hospital avoidance programs. However, little attention has been dedicated to service evaluation of this model and the quality of care provided. The purpose of this study was to evaluate the quality of an aged care NP model of care situated within a HA service in a regional area of Australia...
January 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28048510/su-f-t-499-anatomic-features-for-selection-of-electronic-tissue-compensation-radiotherapy-in-early-stage-breast-cancer-patients-after-breast-conserving-surgery
#7
Y Song, M Zhang, N Yue, L Gan, X Chen, T Zhang, G Ren
PURPOSE: To explore the correlations between anatomic features and dose-volumetric parameters in 3DCRT and eComp whole breast irradiation and identify the feasibility of anatomic parameters to predict the planning method selection. METHODS: We compared the effectiveness between conventional three-dimensional conformal radiotherapy (3DCRT) and electronic tissue compensation (eComp) for whole breast irradiation. 3DCRT and eComp planning techniques were used to generate treatment plans for 60 whole breast patients, respectively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047670/su-f-p-20-predicting-waiting-times-in-radiation-oncology-using-machine-learning
#8
A Joseph, D Herrera, T Hijal, L Hendren, A Leung, J Wainberg, M Sawaf, M Gorshkov, R Maglieri, M Keshavarz, J Kildea
PURPOSE: Waiting times remain one of the most vexing patient satisfaction challenges facing healthcare. Waiting time uncertainty can cause patients, who are already sick or in pain, to worry about when they will receive the care they need. These waiting periods are often difficult for staff to predict and only rough estimates are typically provided based on personal experience. This level of uncertainty leaves most patients unable to plan their calendar, making the waiting experience uncomfortable, even painful...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28039547/phylogenetic-relationships-in-the-family-streptomycetaceae-using-multi-locus-sequence-analysis
#9
David P Labeda, Christopher A Dunlap, Xiaoying Rong, Ying Huang, James R Doroghazi, Kou-San Ju, William W Metcalf
The family Streptomycetaceae, notably species in the genus Streptomyces, have long been the subject of investigation due to their well-known ability to produce secondary metabolites. The emergence of drug resistant pathogens and the relative ease of producing genome sequences has renewed the importance of Streptomyces as producers of new natural products and resulted in revived efforts in isolating and describing strains from novel environments. A previous large study of the phylogeny in the Streptomycetaceae based on 16S rRNA gene sequences provided a useful framework for the relationships among species, but did not always have sufficient resolution to provide definitive identification...
December 30, 2016: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28031325/diethylstilbestrol-activates-catsper-and-disturbs-progesterone-actions-in-human-spermatozoa
#10
Qian-Xing Zou, Zhen Peng, Qing Zhao, Hou-Yang Chen, Yi-Min Cheng, Qing Liu, Yuan-Qiao He, Shi-Qi Weng, Hua-Feng Wang, Tao Wang, Li-Ping Zheng, Tao Luo
STUDY QUESTION: Is diethylstilbestrol (DES), a prototypical endocrine-disrupting chemical (EDC), able to induce physiological changes in human spermatozoa and affect progesterone actions? SUMMARY ANSWER: DES promoted Ca(2+) flux into human spermatozoa by activating the cation channel of sperm (CatSper) and suppressed progesterone-induced Ca(2+) signaling, tyrosine phosphorylation and sperm functions. WHAT IS KNOWN ALREADY: DES significantly impairs the male reproductive system both in fetal and postnatal exposure...
December 28, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28002598/molecular-characterization-and-population-structure-study-of-cambuci-strategy-for-conservation-and-genetic-improvement
#11
D N Santos, C F Nunes, T A Setotaw, R Pio, M Pasqual, G M A Cançado
Cambuci (Campomanesia phaea) belongs to the Myrtaceae family and is native to the Atlantic Forest of Brazil. It has ecological and social appeal but is exposed to problems associated with environmental degradation and expansion of agricultural activities in the region. Comprehensive studies on this species are rare, making its conservation and genetic improvement difficult. Thus, it is important to develop research activities to understand the current situation of the species as well as to make recommendations for its conservation and use...
December 19, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27999228/barriers-to-the-development-of-pediatric-palliative-care-in-italy
#12
Franca Benini, Marcello Orzalesi, Anna de Santi, Sabrina Congedi, Pierina Lazzarin, Federico Pellegatta, Lucia De Zen, Marco Spizzichino, Enrico Alleva
INTRODUCTION: In recent years the emergence of new types of patient, clinical situations, technological frontiers and "health" objectives have changed considerably the needs of ill children, this also concerns pediatric palliative care (PPC). In Italy, despite the introduction of legislation (Law 38/2010) stipulating the right of children and families to access appropriate services for pain control and pediatric palliative care, the availability of these services is still limited. AIM: The aim of this study is to highlight, through a review of the existing data and published literature, the critical issues that obstacle the planning and development of PPC services in Italy...
October 2016: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27994795/long-term-effects-of-untreated-adolescent-idiopathic-scoliosis-a-review-of-the-literature
#13
REVIEW
Hans-Rudolf Weiss, Nikos Karavidas, Marc Moramarco, Kathryn Moramarco
Currently, adolescent idiopathic scoliosis (AIS) is principally regarded as benign, but some researchers have cited serious or extreme effects, including severe pain, cardiopulmonary compromise, social isolation, and even early death. Therefore, exploration of the long-term effects of AIS, the most common type of idiopathic scoliosis, is warranted. The purpose of this review was to examine the long-term studies on the natural history of AIS and/or reviews concerning the long-term effects of untreated AIS. A PubMed search was conducted using the key words idiopathic scoliosis, long-term effects and idiopathic scoliosis, natural history...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27986460/the-effect-of-intrauterine-devices-on-acquisition-and-clearance-of-human-papillomavirus
#14
Sarah H Averbach, Yifei Ma, Karen Smith-McCune, Stephen Shiboski, Anna B Moscicki
BACKGROUND: Previous studies have shown a decrease in cervical cancer associated with intrauterine device use. It has been hypothesized that intrauterine device use may alter the natural history of human papillomavirus infections, preempting development of precancerous lesions of the cervix and cervical cancer, but the effect of intrauterine devices on the natural history of human papillomavirus infection and subsequent development of cervical cancer is poorly understood. OBJECTIVE: The purpose of this study was to evaluate the association between intrauterine device use and cervical high-risk human papillomavirus acquisition and clearance...
December 14, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27968907/occupational-challenges-of-physicians-involved-in-tuberculosis-control-in-china-a-qualitative-study
#15
Shanquan Chen, Hui Zhang, Yan Qu, Yushan Wu, Qian Long, Limei Ran, Qiuji Xue, Kai Chen, Fei Luo, Lan Yao, Lai-Yi Wong, Hong Fung, Manli Chen, Li Xiang
BACKGROUND: Despite its dramatic improvement, China's tuberculosis burden is still high according to the 2015 WHO TB report. Evidence show that experienced physicians do better in reducing delay diagnosis and patient mortality and are more likely to follow the treatment guidelines. However, in China, few studies have focused on physicians specialised in tuberculosis; and these few studies were mainly centred on the prevalence and risk factors among them. We assessed the occupational challenges of these physicians in China...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968860/capitation-reform-in-the-pudong-new-area-of-shanghai-a-retrospective-time-series-analysis
#16
Zhiqun Shu, Limei Jing, Ming Li, Qunfang Zhang, Jiquan Lou, Xiaoming Sun
BACKGROUND: The New Rural Cooperative Medical Scheme (NRCMS) covers 900 million farmers (about 95%) in China, but its fund is at serious risk of deficit. Shanghai, one of the developed cities in China, has developed its Rural Cooperative Medical Scheme and NRCMS as an advanced and exemplary representative of Chinese rural health insurance. The participating rate of NRCMS was 99·90% in Pudong New Area in 2015, which meant 277 310 farmers were involved, accounting for 29% of Shanghai's participants...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968859/the-health-brain-drain-in-rural-areas-about-the-health-personnel-incentive-policy-intervention-in-shanghai-a-longitudinal-study
#17
Kun Liu, Limei Jing, Xuhong Zhou, Yao Huang, Li Wang, Xiaoming Sun
BACKGROUND: The so-called health brain-drain-which refers to the health workers leaving their present jobs to other institutions, especially in rural areas-severely restricts the development of primary healthcare. To solve the problem, Pudong New Area of Shanghai carried out a series of incentive policies such as salary bonus, promotion and housing from July, 2014. In our study we aimed to analyse the change in health brain-drain which resulted from this policy. METHODS: There are 45 community health centres in Pudong, which we classified into 4 categories by geographical division: remote rural, general rural, suburban, and urban...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968826/satisfaction-with-basic-medical-insurance-in-china-a-stratified-cluster-sampling-survey
#18
Ru Chen, Limei Jing, Jing Xu, Junwei Wang, Jiquan Lou, Xiaoming Sun
BACKGROUND: To help drive the consolidation and integrated management of basic medical insurance in China, we analysed participants' satisfaction, and factors associated with satisfaction, for the Urban Employees' Basic Medical Insurance (UEBMI), Urban Residents' Basic Medical Insurance (URBMI), and New Rural Cooperative Medical Scheme (NRCMS). METHODS: Pudong New Area in Shanghai was chosen as a typical sample of basic medical insurance coverage and management...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968825/effectiveness-of-an-incentive-policy-intervention-for-rural-health-care-providers-a-longitudinal-survey-in-shanghai
#19
Limei Jing, Kun Liu, Xuhong Zhou, Li Wang, Jiquan Lou, Xiaoming Sun
BACKGROUND: Grassroots health-care institutions in China are facing a shortage of professionals, especially general practitioners. To encourage health-care providers to come to and stay at rural grassroots institutions, Pudong New Area of Shanghai undertook a series of incentive reforms for rural health-care providers in July, 2014. We evaluated the effectiveness of incentive reform. METHODS: The reform covered Pudong's 32 rural community health centres (CHCs): 12 remote rural CHCs, 11 general rural CHCs, and 9 suburban CHCs...
October 2016: Lancet
https://www.readbyqxmd.com/read/27927243/traditional-mapuche-ecological-knowledge-in-patagonia-argentina-fishes-and-other-living-beings-inhabiting-continental-waters-as-a-reflection-of-processes-of-change
#20
Juana Aigo, Ana Ladio
BACKGROUND: Understanding how people interpret environmental change and develop practices in response to such change is essential to comprehend human resource use. In the cosmology of the American indigenous peoples, as among the Mapuche people, freshwater systems are considered a living entity, where animals have an enormous role to play in the universe of meaning. However, human adaptive responses to freshwater system dynamics are scarcely examined. In this work a survey is carried out in three Mapuche communities of Argentine Patagonia to assess their traditional knowledge of the fishes and other non-human living beings that inhabit lakes and rivers...
December 7, 2016: Journal of Ethnobiology and Ethnomedicine
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