keyword
MENU ▼
Read by QxMD icon Read
search

Periodontal ligament

keyword
https://www.readbyqxmd.com/read/29356241/tumor-necrosis-factor-%C3%AE-regulates-human-follicular-dendritic-cell-secreted-protein-gene-transcription-in-gingival-epithelial-cells
#1
Yasunobu Iwai, Keisuke Noda, Mizuho Yamazaki, Ayako Kato, Masaru Mezawa, Hideki Takai, Yohei Nakayama, Yorimasa Ogata
Follicular dendritic cell-secreted protein (FDC-SP) is a secreted protein expressed in follicular dendritic cells, periodontal ligament and junctional epithelium. To elucidate the transcriptional regulation of the human FDC-SP gene by tumor necrosis factor-α (TNF-α), we conducted real-time PCR, Western blotting, transient transfection analyses with chimeric constructs of the FDC-SP gene promoter linked to a luciferase reporter gene, gel mobility shift and chromatin immunoprecipitation assays using Ca9-22 gingival epithelial cells...
January 22, 2018: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/29354155/the-effect-of-strontium-chloride-on-human-periodontal-ligament-stem-cells
#2
Cecilia Romagnoli, Roberto Zonefrati, Gianna Galli, Alessandra Aldinucci, Niccolò Nuti, Francesco Saverio Martelli, Paolo Tonelli, Annalisa Tanini, Maria Luisa Brandi
The complete repair of periodontal structures remains an exciting challenge that prompts researchers to develop new treatments to restore the periodontium. Recent research has suggested strontium ion to be an attractive candidate to improve osteogenic activity. In this study, we have isolated a clonal finite cell line derived from human periodontal ligament (PDL) in order to assess whether and in which way different doses of SrCl2 (from 0.5 to 500 μg/ml) can influence both the proliferation and the mineralization process, for future application in oral diseases...
September 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/29350756/cytocompatibility-of-biodentine-and-iroot-fs-with-human-periodontal-ligament-cells-an-in-vitro-study
#3
T Luo, J Liu, Y Sun, Y Shen, L Zou
AIM: To evaluate the cytocompatibility of Biodentine and iRoot FS with human periodontal ligament cells (hPDLCs). METHODOLOGY: hPDLCs were characterized by flow cytometry and immunocytochemical analysis. hPDLC adhesion was assessed by scanning electron microscopy at day 3; proliferation by live/dead assay at day 1, 3 and 7; and osteogenic differentiation by alkaline phosphatase (ALP) activity staining, ALP quantification analysis and qRT-PCR at day 7 and 14. Data were analysed with ANOVA and independent sample t-tests with SPSS 21...
January 19, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29341890/periodontal-diseases-and-adverse-pregnancy-outcomes-is-there-a-role-for-vitamin-d
#4
REVIEW
Anne Marie Uwitonze, Peace Uwambaye, Moses Isyagi, Chrispinus H Mumena, Alice Hudder, Afrozul Haq, Kamrun Nessa, Mohammed S Razzaque
Studies have shown a relationship between maternal periodontal diseases (PDs) and premature delivery. PDs are commonly encountered oral diseases which cause progressive damage to the periodontal ligament and alveolar bones, leading to loss of teeth and oral disabilities. PDs also adversely affect general health by worsening cardiovascular and metabolic diseases. Moreover, maternal PDs are thought to be related to increasing the frequency of preterm-birth with low birth weight (PBLBW) new-borns. Prematurity and immaturity are the leading causes of prenatal and infant mortality and is a major public health problem around the world...
January 13, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29333326/evaluation-of-the-periodontal-regenerative-properties-of-patterned-human-periodontal-ligament-stem-cell-sheets
#5
Joong-Hyun Kim, Seok-Yeong Ko, Justin Ho Lee, Deok-Ho Kim, Jeong-Ho Yun
Purpose: The aim of this study was to determine the effects of patterned human periodontal ligament stem cell (hPDLSC) sheets fabricated using a thermoresponsive substratum. Methods: In this study, we fabricated patterned hPDLSC sheets using nanotopographical cues to modulate the alignment of the cell sheet. Results: The hPDLSCs showed rapid monolayer formation on various surface pattern widths. Compared to cell sheets grown on flat surfaces, there were no significant differences in cell attachment and growth on the nanopatterned substratum...
December 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29331511/maresin-1-regulates-autophagy-and-inflammation-in-human-periodontal-ligament-cells-through-glycogen-synthase-kinase-3%C3%AE-%C3%AE-catenin-pathway-under-inflammatory-conditions
#6
Li Du, Yucheng Li, Weifeng Liu
OBJECTIVE: Accumulating lines of evidence suggest that maresin 1 (MaR-1) exerts anti-inflammatory effects in many cell types and plays beneficial roles in inflammatory disease, such as peritonitis and colitis. Moreover, it has been demonstrated that MaR-1 play protective roles against localized aggressive periodontitis. However, the function and mechanism of MaR-1 in human periodontal ligament cells (PDL) cells from periodontitis are poorly understood. The present study aimed to clarify the effects and molecular mechanism of MaR-1 in PDL cell survival and inflammation...
December 23, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29321613/evaluation-of-in-vivo-digital-root-reconstruction-based-on-anatomical-characteristics-of-the-periodontal-ligament-using-cone-beam-computed-tomography
#7
Chenxin Wang, Yi Liu, Siwei Wang, Yong Wang, Yijiao Zhao
This study's aim was to develop and validate an approach to automatically extract and reconstruct three-dimensional (3D) digital root models from in vivo teeth based on the anatomical characteristics of the periodontal ligament using cone beam computed tomography (CBCT) data. Prior to undergoing dental extractions for orthodontic purposes, the CBCT data of each study participant were collected and imported into Mimics software to reconstruct 3D in vivo digital root models (test models). Twenty roots of 17 teeth extracted from the study's participants were scanned using a dental scanner to obtain 3D in vitro digital root models (reference models)...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29321271/incremental-distribution-of-strontium-and-zinc-in-great-ape-and-fossil-hominin-cementum-using-synchrotron-x-ray-fluorescence-mapping
#8
Christopher Dean, Adeline Le Cabec, Kathryn Spiers, Yi Zhang, Jan Garrevoet
Cementum and the incremental markings it contains have been widely studied as a means of ageing animals and retrieving information about diet and nutrition. The distribution of trace elements in great ape and fossil hominin cementum has not been studied previously. Synchrotron X-ray fluorescence (SXRF) enables rapid scanning of large tissue areas with high resolution of elemental distributions. First, we used SXRF to map calcium, phosphorus, strontium and zinc distributions in great ape dentine and cementum...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29314755/replanted-teeth-stored-in-a-newly-developed-powdered-coconut-water-formula
#9
Manuella Verdinelli de Paula Reis, Carlos José Soares, Priscilla Barbosa Ferreira Soares, Aletheia Moraes Rocha, Cristiane Clemente de Mello Salgueiro, Márcia Helena Niza Ramalho Sobral, Camilla Christian Gomes Moura
BACKGROUND/AIM: A newly developed powdered coconut water formulae (ACP-404) has been proposed to preserve periodontal ligament cell viability. The aim of this study was to investigate the periodontal healing of dog teeth replanted after storage in ACP-404 with two different osmolalities. MATERIALS AND METHODS: Sixty teeth of 10 adult beagle dogs were extracted and randomly subjected to the following protocols: immediate replantation after extraction (positive control); dry conditions (negative control); and storage in ACP-404 I (G1), ACP-404 II (G2), in coconut water long-shelf (G3), or in pH-neutralized coconut water long-shelf (G4) for 50 minutes before replantation...
January 5, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/29313816/osteopontin-regulates-dentin-and-alveolar-bone-development-and-mineralization
#10
B L Foster, M Ao, C R Salmon, M B Chavez, T N Kolli, A B Tran, E Y Chu, K R Kantovitz, M Yadav, S Narisawa, J L Millán, F H Nociti, M J Somerman
The periodontal complex is essential for tooth attachment and function and includes the mineralized tissues, cementum and alveolar bone, separated by the unmineralized periodontal ligament (PDL). To gain insights into factors regulating cementum-PDL and bone-PDL borders and protecting against ectopic calcification within the PDL, we employed a proteomic approach to analyze PDL tissue from progressive ankylosis knock-out (Ank-/-) mice, featuring reduced PPi, rapid cementogenesis, and excessive acellular cementum...
December 4, 2017: Bone
https://www.readbyqxmd.com/read/29311578/promoting-induced-pluripotent-stem-cell-driven-biomineralization-and-periodontal-regeneration-in-rats-with-maxillary-molar-defects-using-injectable-bmp-6-hydrogel
#11
Ke-Hung Chien, Yuh-Lih Chang, Mong-Lien Wang, Jen-Hua Chuang, Ya-Chi Yang, Ming-Cheng Tai, Chien-Ying Wang, Yung-Yang Liu, Hsin-Yang Li, Jiang-Torng Chen, Shou-Yen Kao, Hen-Li Chen, Wen-Liang Lo
Periodontal disease may cause considerable destruction of alveolar bone, periodontal ligaments (PDLs) and cementum and even lead to progressive oral dysfunction. Periodontal tissue regeneration is the ultimate goal of periodontal disease treatment to reconstruct both structures and functions. However, the regenerative efficiency is low, possibly due to the lack of a proper periodontal microenvironment. In this study, we applied an injectable and thermosensitive chitosan/gelatin/glycerol phosphate hydrogel to provide a 3D environment for transplanted stem cells and to enhance stem cell delivery and engraftment...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29306866/mechanical-stress-potentiates-the-differentiation-of-periodontal-ligament-stem-cells-into-keratocytes
#12
Jialin Chen, Wei Zhang, Ludvig J Backman, Peyman Kelk, Patrik Danielson
AIMS: To explore the role of corneal-shaped static mechanical strain on the differentiation of human periodontal ligament stem cells (PDLSCs) into keratocytes and the possible synergistic effects of mechanics and inducing medium. METHODS: PDLSCs were exposed to 3% static dome-shaped mechanical strain in a Flexcell Tension System for 3 days and 7 days. Keratocyte phenotype was determined by gene expression of keratocyte markers. Keratocyte differentiation (inducing) medium was introduced in the Flexcell system, either continuously or intermittently combined with mechanical stimulation...
January 6, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29304428/approach-towards-the-porous-fibrous-structure-of-the-periodontal-ligament-using-micro-computerized-tomography-and-finite-element-analysis
#13
J Ortún-Terrazas, J Cegoñino, U Santana-Penín, U Santana-Mora, A Pérez Del Palomar
The periodontal ligament (PDL) is a porous and fibrous soft tissue situated around the tooth, which plays a key role in the transmission of loads from the tooth to the alveolar bone of the mandible. Although several studies have tried to characterize its mechanical properties, the behaviour of this tissue is not clear yet. In this study, a new simulation methodology based on a material model which considers the contribution of porous and fibrous structure with different material model formulations depending on the effort direction is proposed...
December 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29304003/a-high-resolution-proteomic-landscaping-of-primary-human-dental-stem-cells-identification-of-shed-and-pdlsc-specific-biomarkers
#14
Vasiliki Taraslia, Stefania Lymperi, Vasiliki Pantazopoulou, Athanasios K Anagnostopoulos, Issidora S Papassideri, Efthimia K Basdra, Marianna Bei, Evangelos G Kontakiotis, George Th Tsangaris, Dimitrios J Stravopodis, Ema Anastasiadou
Dental stem cells (DSCs) have emerged as a promising tool for basic research and clinical practice. A variety of adult stem cell (ASC) populations can be isolated from different areas within the dental tissue, which, due to their cellular and molecular characteristics, could give rise to different outcomes when used in potential applications. In this study, we performed a high-throughput molecular comparison of two primary human adult dental stem cell (hADSC) sub-populations: Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Periodontal Ligament Stem Cells (PDLSCs)...
January 5, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29289709/periostin-dentin-matrix-protein-1-and-p2rx7-ion-channel-in-human-teeth-and-periodontal-ligament
#15
I Menéndez-Diaz, J D Muriel, O García-Suárez, A Obaya, S Cal, J Cobo, J A Vega, T Cobo
The periostin is a matricellular protein present in the human periodontal ligament and human dental pulp-derived cells lines, that up-regulates the in vitro expression of some genes involved in the dentin mineralization, such as dentin matrix protein 1 and P2×7-ion channel receptor. Here we investigated the distribution of periostin in human teeth and periodontal ligaments, mapping in parallel the localization of dentin matrix protein 1 and P2×7-ion channel receptor to establish whether or not they are expressed in the same places as periostin...
December 28, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29288504/cell-therapy-with-allogenic-canine-periodontal-ligament-derived-cells-in-periodontal-regeneration-of-critical-size-defects
#16
J Nuñez, N Sanchez, F Vignoletti, I Sanz-Martin, R Caffesse, S Santamaria, J A Garcia-Sanz, M Sanz
AIM: The objective of this in-vivo experimental study to evaluate the regenerative potential of a cell therapy combining allogenic periodontal ligament derived cells with in a xenogeneic bone substitute in a similar experimental model. METHODS: In 9 beagle dogs, critical-size 6 mm supra-alveolar periodontal defects were created around the PIII and PIV. The resulting supra-alveolar defects were randomly treated with either 1.4 x 106 allogenic canine periodontal ligament-derived cells seeded on de-proteinized bovine bone mineral with 10% collagen (DBBM-C) (test group), or DBBM-C without cells (control group)...
December 29, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29287702/scutellaria-baicalensis-ameliorates-the-destruction-of-periodontal-ligament-via-inhibition-of-inflammatory-cytokine-expression
#17
Mi Hye Kim, Haesu Lee, You Yeon Choi, Dae Hoon Lee, Woong Mo Yang
BACKGROUND: Scutellaria baicalensis (SB) is widely used as a medicinal plant to treat various inflammatory diseases. In the present study, we investigated the effects of SB on periodontitis in ligature-induced experimental rat model. METHODS: Rats were subjected to a ligature placement around the first molar of the mandible to induce periodontitis. 100 mg/kg SB extracts were orally administered for 14 days. The molar tissues were stained with 1% methylene blue...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29287661/time-dependent-behavior-of-porcine-periodontal-ligament-a-combined-experimental-numeric-in-vitro-study
#18
Thomas Johannes Knaup, Cornelius Dirk, Susanne Reimann, Ludger Keilig, Meike Eschbach, Heike Korbmacher-Steiner, Christoph Bourauel
INTRODUCTION: The aim of this study was to analyze the time-dependent in-vitro behavior of the periodontal ligament (PDL) by determining the material parameters using specimens of porcine jawbone. Time-dependent material parameters to be determined were expected to complement the results from earlier biomechanical studies. METHODS: Five mandibular deciduous porcine premolars were analyzed in a combined experimental-numeric study. After selecting suitable specimens (excluding root resorption) and preparing the measurement system, the specimens were deflected by a distance of 0...
January 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29284947/an-in-vitro-comparison-of-coconut-water-milk-and-saline-in-maintaining-periodontal-ligament-cell-viability
#19
Vivian Flourish D'Costa, Madhu Keshava Bangera, Shravan Kini, Shakkira Moosa Kutty, Mallikarjuna Ragher
Background and Objectives: Two of the most critical factors affecting the prognosis of an avulsed tooth after replantation are extraoral dry time and the storage media in which the tooth is placed before treatment is rendered. The present study is undertaken to evaluate the periodontal ligament (PDL) cell viability after storage of teeth in different storage media, namely, coconut water, milk, and saline. Materials and Methods: Forty sound human premolars undergoing extraction for orthodontic purpose were selected...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284459/autotransplantation-of-mature-and-immature-third-molars-in-23-chinese-patients-a-clinical-and-radiological-follow-up-study
#20
Haozhe Tang, Zhengyan Shen, Minhong Hou, Ligeng Wu
BACKGROUND: We investigated the clinical and radiographic outcomes of autotransplanted teeth over a follow-up period of 2 to 8 years, and summarize the findings of other relevant studies with regard to the primary factors that influence a good prognosis in such patients. METHODS: Twenty-three patients (6 men, 17 women) who attended Tanggu Stomatological Hospital, Tianjin, China, from 2008 through 2013, were included in the study. These patients presented with a variety of dental problems, including tooth loss, residual crowns, missing first or second molars, dental trauma, tooth fracture, and unrestored teeth...
December 28, 2017: BMC Oral Health
keyword
keyword
81346
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"