keyword
MENU ▼
Read by QxMD icon Read
search

undiagnosed

keyword
https://www.readbyqxmd.com/read/29682432/an-unusually-aggressive-large-cell-carcinoma-of-the-lung-undiagnosed-until-autopsy
#1
Kartikeya Rajdev, Abdul Hasan Siddiqui, Uroosa Ibrahim, Prateek Patibandla, Tahir Khan, Dany El-Sayegh
Large cell carcinoma (LCC) of the lung has a rapid mean volume doubling time (VDT) of around 67-134 days. In some cases of LCC where the VDT is extremely rapid, clinical presentation may mimic acute lung pathologies such as pneumonia. We describe a rare presentation of an aggressive LCC of the lung with an estimated VDT of around two weeks. A 52-year-old male with a history schizophrenia presented with fever, cough, and dyspnea for three weeks duration. His medical history was significant for a recent admission six weeks before current presentation for myocardial infarction (MI) and pneumonia...
February 19, 2018: Curēus
https://www.readbyqxmd.com/read/29682250/esophageal-aperistalsis-in-a-patient-with-lipoid-proteinosis
#2
Behrooz Afshar, Anahita Sadeghi, Mohammad Amani, Ali Ali Asgari
Lipoid proteinosis is a rare disorder with autosomal recessive inheritance, characterized by progressive deposition of hyaline material in the skin, mucous membrane, and different organs of the body, resulting in a multitude of clinical manifestations. A 34-year-old woman presented with hoarseness, dysphagia, eyelid beeding, and acneiform scars on the facial skin and extremities. The patient was diagnosed clinically as having lipoid proteinosis, which was confirmed by laryngeal biopsy. The objective of the present report is to describe this rare entity...
January 2018: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29680581/middle-east-respiratory-syndrome-coronavirus-risk-factors-and-determinants-of-primary-household-and-nosocomial-transmission
#3
REVIEW
David S Hui, Esam I Azhar, Yae-Jean Kim, Ziad A Memish, Myoung-Don Oh, Alimuddin Zumla
Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal zoonosis that causes death in 35·7% of cases. As of Feb 28, 2018, 2182 cases of MERS-CoV infection (with 779 deaths) in 27 countries were reported to WHO worldwide, with most being reported in Saudi Arabia (1807 cases with 705 deaths). MERS-CoV features prominently in the WHO blueprint list of priority pathogens that threaten global health security. Although primary transmission of MERS-CoV to human beings is linked to exposure to dromedary camels (Camelus dromedarius), the exact mode by which MERS-CoV infection is acquired remains undefined...
April 18, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29680176/perianesthesia-nurses-survey-of-their-knowledge-and-practice-with-obstructive-sleep-apnea
#4
Andrea M Erwin, Kim A Noble, June Marshall, Susan Cooper
PURPOSE: Anesthesia, sedation, and analgesia can negatively impact adult patients with obstructive sleep apnea (OSA). Despite known risks, current evidence, and practice guidelines, insufficient evidence exists that standardization and clinical application of OSA screening tools, problem identification, and perioperative nursing intervention and management strategies are consistently implemented for OSA patients across perianesthesia settings. The purpose of this study was to conduct a knowledge and practice assessment of perianesthesia nurses who care for adult patients with diagnosed or undiagnosed OSA...
April 18, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29679303/do-the-sglt-2-inhibitors-offer-more-than-hypoglycemic-activity
#5
REVIEW
Eduardo Flores, Carlos G Santos-Gallego, Nely Diaz-Mejía, Juan Jose Badimon
Type 2 diabetes mellitus (T2DM) is one of the most common chronic health conditions in the USA; it affects approximately 10% of adults with up to one-quarter being undiagnosed. T2DM is associated with substantial cardiovascular (CV) morbidity and mortality. T2DM is a pathological condition characterized by elevated levels of glucose and associated with high CV risk. Traditional hypoglycemic drugs have demonstrated their capability for effective and maintained management of high glucose levels, but they have not significantly impacted on the incidence of CV events...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29679253/fever-of-unknown-origin-fuo-cmv-infectious-mononucleosis-or-lymphoma
#6
Burke A Cunha, Karishma Chawla
Fever of unknown origin (FUO) refers to fevers of > 101 °F that persist for > 3 weeks and remain undiagnosed after a focused inpatient or outpatient workup. FUO may be due to infectious, malignant/neoplastic, rheumatic/inflammatory, or miscellaneous disorders. The FUO category determines the focus of the diagnostic workup. In the case presented of an FUO in a young woman, there were clinical findings of both CMV infectious mononucleosis or a lymphoma, e.g., highly elevated ESR, elevated ferritin levels, and elevated ACE level, β-2 microglobulins...
April 20, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29678190/neonatal-and-congenital-malaria-a-case-series-in-malaria-endemic-eastern-uganda
#7
Peter Olupot-Olupot, Emma I E Eregu, Ketty Naizuli, Julie Ikiror, Linda Acom, Kathy Burgoine
BACKGROUND: Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relatively low rates in malaria endemic regions. However, recent reports suggest that the number of NCM cases is increasing, and its epidemiology remains poorly described. NCM can mimic other neonatal conditions and because it is thought to be rare, blood film examinations for malaria are not always routinely performed...
April 20, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29676000/the-2016-hiv-diagnosis-and-care-cascade-in-new-south-wales-australia-meeting-the-unaids-90-90-90-targets
#8
Phillip Keen, Richard T Gray, Barbara Telfer, Rebecca Guy, Heather-Marie Schmidt, Bill Whittaker, Jo Holden, Martin Holt, Anthony Kelleher, David Wilson, Denton Callander, David A Cooper, Garrett Prestage, Christine Selvey, Andrew E Grulich
INTRODUCTION: The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targets. METHODS: To estimate the number of people living with diagnosed HIV (PLDHIV) we used NSW data from the Australian National HIV Registry, enhanced by surveillance among people recently diagnosed with HIV to improve migration estimates...
April 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29675035/trio-clinical-exome-sequencing-in-a-patient-with-multicentric-carpotarsal-osteolysis-syndrome-first-case-report-in-the-balkans
#9
Aleksandra Stajkovska, Sanja Mehandziska, Margarita Stavrevska, Kristina Jakovleva, Natasha Nikchevska, Zan Mitrev, Ivan Kungulovski, Gjorgje Zafiroski, Velibor Tasic, Goran Kungulovski
Exome sequencing can interrogate thousands of genes simultaneously and it is becoming a first line diagnostic tool in genomic medicine. Herein, we applied trio clinical exome sequencing (CES) in a patient presenting with undiagnosed skeletal disorder, minor facial abnormalities, and kidney hypoplasia; her parents were asymptomatic. Testing the proband and her parents led to the identification of a de novo mutation c.188C>T (p.Pro63Leu) in the MAFB gene, which is known to cause multicentric carpotarsal osteolysis syndrome (MCTO)...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29671046/digeorge-syndrome-relevance-of-psychiatric-symptoms-in-undiagnosed-adult-patients
#10
Christoph Kraus, Thomas Vanicek, Ana Weidenauer, Tav Khanaqa, Mara Stamenkovic, Rupert Lanzenberger, Matthäus Willeit, Siegfried Kasper
DiGeorge syndrome or 22q11.2 deletion syndrome is one of the most common genetic microdeletion syndromes in humans. In addition to physical manifestations, DiGeorge syndrome is associated with a high prevalence of psychiatric disorders, such as intellectual disability, schizophrenia and attention-deficit/hyperactivity disorder. Usually, the diagnosis of DiGeorge syndrome is made in early childhood. This article reports on the late diagnosis of a patient with panic disorder and comorbid major depression at the age of 51...
April 18, 2018: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29670774/emergent-presentation-of-an-adult-with-undiagnosed-coarctation-of-the-aorta
#11
Shannon Armistead, David Mullins, Stephen Sherick, John Ashurst
Coarctation of the aorta is typically thought to be a childhood disease. However, emergency physicians must keep a broad differential diagnosis when faced with a young patient with signs and symptoms of acute congestive heart failure. The authors present a case of newly diagnosed coarctation of the aorta in a 26-year-old male who was first misdiagnosed with pneumonia.
2018: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/29669571/sex-differences-in-pulmonary-arterial-hypertension-role-of-infection-and-autoimmunity-in-the-pathogenesis-of-disease
#12
REVIEW
Kyle A Batton, Christopher O Austin, Katelyn A Bruno, Charles D Burger, Brian P Shapiro, DeLisa Fairweather
Registry data worldwide indicate an overall female predominance for pulmonary arterial hypertension (PAH) of 2-4 over men. Genetic predisposition accounts for only 1-5% of PAH cases, while autoimmune diseases and infections are closely linked to PAH. Idiopathic PAH may include patients with undiagnosed autoimmune diseases based on the relatively high presence of autoantibodies in this group. The two largest PAH registries to date report a sex ratio for autoimmune connective tissue disease-associated PAH of 9:1 female to male, highlighting the need for future studies to analyze subgroup data according to sex...
April 18, 2018: Biology of Sex Differences
https://www.readbyqxmd.com/read/29667577/people-living-with-undiagnosed-hiv-infection-and-a-low-cd4-count-estimates-from-surveillance-data-italy-2012-to-2014
#13
Vincenza Regine, Maria Dorrucci, Patrizio Pezzotti, Alessia Mammone, Chantal Quinten, Anastasia Pharris, Barbara Suligoi, The Regional Representatives Of The National Hiv Surveillance System
Background and aimsLate HIV diagnosis is associated with onward HIV transmission, higher morbidity, mortality and healthcare costs. In Italy, more than half of people living with HIV were diagnosed late during the last decade, with a CD4 count < 350 cells/mm3 at diagnosis. We aimed to determine the number and characteristics of people living with undiagnosed HIV infection and low CD4 counts in Italy. Methods: Data on newly reported HIV diagnoses from 2012 -2014 were obtained from the national HIV surveillance system...
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29666723/a-challenging-case-of-severe-ulcerative-colitis-following-the-initiation-of-secukinumab-for-ankylosing-spondylitis
#14
Dean Ehrlich, Nimah Jamaluddin, Joseph Pisegna, David Padua
Secukinumab is an interleukin-17 inhibitor used for the treatment of ankylosing spondylitis (AS), psoriasis, and psoriatic arthritis. The risk of exacerbating underlying inflammatory bowel disease (IBD) in patients being treated with secukinumab for other conditions is controversial. We document a patient with AS and previously undiagnosed IBD, found to be in a severe ulcerative colitis flare shortly after receiving the loading dose of secukinumab. There are no guidelines regarding biologic salvage therapy for IBD in the setting of active treatment with another biologic agent...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29665864/recurrent-pregnancy-loss-is-associated-to-leaky-gut-a-novel-pathogenic-model-of-endometrium-inflammation
#15
C Tersigni, S D'Ippolito, F Di Nicuolo, R Marana, V Valenza, V Masciullo, F Scaldaferri, F Malatacca, C de Waure, A Gasbarrini, G Scambia, N Di Simone
BACKGROUND: Recurrent pregnancy loss (RPL) occurs in 3-5% in about 30% of cases no cause can be found. Women with RPL show higher prevalence of undiagnosed gut disorders. Furthermore, in endometrial tissues of RPL women, higher expression of pro-inflammatory cytokines and Nalp-3 inflammasome has been observed. Aim of this study was to investigate whether an abnormal gut permeability might occur in RPL women and allow passage into systemic circulation of pro-inflammatory molecules able to induce endometrial inflammation...
April 17, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29661504/stress-induced-hyperglycemia-on-complications-in-non-critically-elderly-hospitalized-patients
#16
F J Carrasco-Sánchez, J Carretero-Gómez, R Gómez-Huelgas, M A Garcia-Ordoñez, M V Pardo-Ortega, B de Escalante-Yanguela, L Mateos-Polo, F Formiga, J Ena
AIMS: Hospital complications and hyperglycemia are common in elderly patients during hospitalization. Our aim was to analyze the relationship between hyperglycemia and hospital complications in an ageing population. METHODS: We conducted an observational study to evaluate the association between maximum blood glucose (MBG) levels and hospital complications. Patients were stratified according to the quartiles of MBG levels. Diabetes mellitus (DM) was determined by patient history and/or admission glycated hemoglobin (HbA1c) level ≥6...
April 13, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29661496/abuse-cancer-and-sexual-dysfunction-in-women-a-potentially-vicious-cycle
#17
REVIEW
Brittany F Lees, Taylor P Stewart, Joanne K Rash, Shirley R Baron, Stacy Tessler Lindau, David M Kushner
More than 30% of women have a history of abuse. Women with cancer may be at substantially increased risk for abuse, but this issue is rarely discussed in the course of oncology care. Women with a history of abuse who present for cancer care commonly have a high prevalence of co-morbid illness. Sexual dysfunction, a highly prevalent but under-recognized condition among women of all ages, is also more common among both women with a history of abuse and women with cancer. Although common after cancer, sexual dysfunction, like abuse, can be stigmatizing and often goes undiagnosed and untreated...
April 13, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29661090/are-disease-severity-sleep-related-problems-and-anxiety-associated-with-work-functioning-in-patients-with-obstructive-sleep-apnoea
#18
Vladimira Timkova, Iveta Nagyova, Sijmen A Reijneveld, Ruzena Tkacova, Jitse P van Dijk, Ute Bültmann
PURPOSE: To examine whether Obstructive Sleep Apnoea severity, sleep-related problems, and anxiety are associated with work functioning in Obstructive Sleep Apnoea patients, when controlled for age, gender and type of occupation. To investigate whether anxiety moderates the associations between sleep-related problems and work functioning. MATERIALS AND METHODS: We included 105 Obstructive Sleep Apnoea patients (70% male; mean age 46.62 ± 9.79 years). All patients completed the Pittsburgh Sleep Quality Index, the Epworth Sleepiness Scale, the Beck Anxiety Inventory, and the Work Role Functioning Questionnaire-2...
April 17, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29660967/a-call-for-implementing-preferred-practices-for-brain-injury-screening-in-youth-to-improve-transition
#19
Drew A Nagele, Melissa McCart, Stephen R Hooper
BACKGROUND: It is vital to engage in systematic screening to identify and serve children who may have sustained an acquired brain injury (ABI) - either traumatic or non-traumatic, so they can be successfully transitioned between environments and life stages. This is particularly important for children and adolescents given the impact an ABI can have on learning and social functioning over the course of the neurodevelopmental process. A pattern of repeated, undiagnosed mild brain injuries may lead to mood or behavior disorders, learning problems...
April 7, 2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29660590/detection-of-neurodevelopmental-diversity-in-memory-clinics-validation-of-a-self-report-measure
#20
Alon Seifan, Chiashin Shih, Katherine Hackett, Max J Pensack, Matthew W Schelke, Michael Lin, Hemali Patel, Christine A Ganzer, Mahreen Ahmed, Robert Krikorian, Peter Tamboer, Adolfo M Henriquez, Richard S Isaacson, Sheila Steinhof
BACKGROUND: Neurodevelopmental learning and attentional disorders (NLAD) such as dyslexia, dyscalculia and attention deficit hyperactivity disorder (ADHD) affect at least 6% of the adult population or more. They are associated with atypical cognitive patterns in early and adult life. The cognitive patterns of affected individuals in late life have never been described. One main challenge is detecting individuals in clinical settings during which mild cognitive changes could be confounding the clinical presentation...
April 13, 2018: Research in Developmental Disabilities
keyword
keyword
81343
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"