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https://www.readbyqxmd.com/read/29455915/fatty-acid-composition-enzyme-activities-and-metallothioneins-in-donax-trunculus-mollusca-bivalvia-from-polluted-and-reference-sites-in-the-gulf-of-annaba-algeria-pattern-of-recovery-during-transplantation
#1
Amina Rabei, Aziz Hichami, Hayet Beldi, Sandrine Bellenger, Naim Akhtar Khan, Noureddine Soltani
The gulf of Annaba, the most important touristic and economic coastal zone located in Northeast Algeria, is contaminated by several pollutants from urban, agricultural, harbor and industrial activities. Elevated levels of heavy metals were detected in a locally prevalent edible mollusk Donax trunculus (Bivalvia, Donacidae) widely used as a sentinel species for the assessment of marine pollution. The present work aims to measure the difference between two localities, one being full of different pollutants (Sidi Salem) and the other being relatively clean (El Battah) and to evaluate the ability of D...
February 15, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29451219/low-frequency-pulsed-electromagnetic-field-pretreated-bone-marrow-derived-mesenchymal-stem-cells-promote-the-regeneration-of-crush-injured-rat-mental-nerve
#2
NaRi Seo, Sung-Ho Lee, Kyung Won Ju, JaeMan Woo, BongJu Kim, SoungMin Kim, Jeong Won Jahng, Jong-Ho Lee
Bone marrow-derived mesenchymal stem cells (BMSCs) have been shown to promote the regeneration of injured peripheral nerves. Pulsed electromagnetic field (PEMF) reportedly promotes the proliferation and neuronal differentiation of BMSCs. Low-frequency PEMF can induce the neuronal differentiation of BMSCs in the absence of nerve growth factors. This study was designed to investigate the effects of low-frequency PEMF pretreatment on the proliferation and function of BMSCs and the effects of low-frequency PEMF pre-treated BMSCs on the regeneration of injured peripheral nerve using in vitro and in vivo experiments...
January 2018: Neural Regeneration Research
https://www.readbyqxmd.com/read/29444905/renal-interstitial-platelet-derived-growth-factor-receptor-%C3%AE-cells-support-proximal-tubular-regeneration
#3
Ina Maria Schiessl, Alexandra Grill, Katharina Fremter, Dominik Steppan, Maj-Kristina Hellmuth, Hayo Castrop
BACKGROUND: The kidney is considered to be a structurally stable organ with limited baseline cellular turnover. Nevertheless, single cells must be constantly replaced to conserve the functional integrity of the organ. PDGF chain B (PDGF-BB) signaling through fibroblast PDGF receptor- β (PDGFR β ) contributes to interstitial-epithelial cell communication and facilitates regenerative functions in several organs. However, the potential role of interstitial cells in renal tubular regeneration has not been examined...
February 14, 2018: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29444602/evaluating-integrative-cancer-clinics-with-the-claim-assessment-profile-an-example-with-the-inspirehealth-clinic
#4
Lara Hilton, Pamela Elfenbaum, Shamini Jain, Meredith Sprengel, Wayne B Jonas
BACKGROUND: The evaluation of freestanding integrative cancer clinical programs is challenging and is rarely done. We have developed an approach called the Claim Assessment Profile (CAP) to identify whether evaluation of a practice is justified, feasible, and likely to provide useful information. OBJECTIVES: A CAP was performed in order to (1) clarify the healing claims at InspireHealth, an integrative oncology treatment program, by defining the most important impacts on its clients; (2) gather information about current research capacity at the clinic; and (3) create a program theory and path model for use in prospective research...
March 2018: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29441230/forecasting-biodiversity-in-breeding-birds-using-best-practices
#5
David J Harris, Shawn D Taylor, Ethan P White
Biodiversity forecasts are important for conservation, management, and evaluating how well current models characterize natural systems. While the number of forecasts for biodiversity is increasing, there is little information available on how well these forecasts work. Most biodiversity forecasts are not evaluated to determine how well they predict future diversity, fail to account for uncertainty, and do not use time-series data that captures the actual dynamics being studied. We addressed these limitations by using best practices to explore our ability to forecast the species richness of breeding birds in North America...
2018: PeerJ
https://www.readbyqxmd.com/read/29440798/rural-palliative-care-in-north-india-rapid-evaluation-of-a-program-using-a-realist-mixed-method-approach
#6
Daniel F Munday, Erna Haraldsdottir, Manju Manak, Ann Thyle, Cathy M Ratcliff
Context: Palliative care has not developed widely in rural North India. Since 2010, the Emmanuel Hospitals Association (EHA) has been developing a model of palliative care appropriate for this setting, based on teams undertaking home visits with the backup of outpatient and inpatient services. A project to further develop the model operated from 2012 to 2015 supported by funding from the UK. Aims: This study aims to evaluate the EHA palliative care project. Settings and Design: Rapid evaluation method using a mixed method realist approach at the five project hospital sites...
January 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29428108/diagnostic-yield-of-eus-fna-of-small-%C3%A2-15%C3%A2-mm-solid-pancreatic-lesions-using-a-25-gauge-needle
#7
Stefano Francesco Crinò, Maria Cristina Conti Bellocchi, Laura Bernardoni, Erminia Manfrin, Alice Parisi, Antonio Amodio, Nicolò De Pretis, Luca Frulloni, Armando Gabbrielli
BACKGROUND: Early detection of small solid pancreatic lesions is increasingly common. To date, few and contradictory data have been published about the relationship between lesion size and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) diagnostic yield. The aim of this study was to assess the relation between the size of solid pancreatic lesions and the diagnostic yield of EUS-FNA using a 25-gauge needle in a center without available rapid on-site evaluation. METHODS: In the retrospective cohort study, we selected patients who underwent EUS-FNA for solid pancreatic lesions with a 25-gauge needle from October 2014 to October 2015...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29424404/-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#8
Gonzalo Labarca, Iván Caviedes, Erik Folch, Adnan Majid, Sebastián Fernández-Bussy
In the last years, several techniques have been developed to obtain a prompt diagnosis or rule out lung cancer. Endobronchial ultrasound- guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure with a high diagnostic yield for mediastinal and central pulmonary lesions. This procedure is especially useful for lung cancer diagnosis and mediastinal staging. Two different types of EBUS are currently available: Radial EBUS and lineal EBUS. Each one has technical differences together with a range of clinical indications...
September 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29419365/meek-micrografting-history-indications-technique-physiology-and-experience-a-review-article
#9
Eduardo Camacho Quintero, Jesús Francisco Escrivá Machado, Roger Andres Damian Robles
AIMS: Traumatic loss of skin, particularly in major burns, requires skin grafting to repair the tissue. For a large burn, where donor sites are limited, the skin graft may need to be expanded. In addition, rapid wound closure is a large factor in successful recovery and is usually achieved by debridement and skin grafting. Micrografting was introduced by Meek and involved dividing the skin into small pieces, allowing for up to a tenfold skin expansion. METHODS: We conducted a review of the literature, searched via Medline, Pubmed and Embase (from 1958 to June 2017), searching to identify studies and reports of micrografting...
February 1, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29417376/complications-of-a-poly-l-lactic-acid-and-polyglycolic-acid-osteosynthesis-device-for-internal-fixation-in-maxillofacial-surgery
#10
Shintaro Sukegawa, Takahiro Kanno, Kenichi Matsumoto, Yuka Sukegawa-Takahashi, Masanori Masui, Yoshihiko Furuki
The purpose of this study was to retrospectively evaluate and examine the incidence of complications using poly-L-lactic acid and polyglycolic acid (PLLA/PGA) copolymer plate system in maxillofacial osteosynthesis. The retrospective study included 87 patients (50 men, 37 women), who needed maxillofacial surgery. We examined the proportion of complications and their factors from clinical data. A comparison was also made for plate decomposition using the molecular weight of the plate without plate exposure and complications...
February 7, 2018: Odontology
https://www.readbyqxmd.com/read/29415724/improvement-of-malaria-diagnostic-system-based-on-acridine-orange-staining
#11
Masatsugu Kimura, Isao Teramoto, Chim W Chan, Zulkarnain Md Idris, James Kongere, Wataru Kagaya, Fumihiko Kawamoto, Ryoko Asada, Rie Isozumi, Akira Kaneko
BACKGROUND: Rapid diagnosis of malaria using acridine orange (AO) staining and a light microscope with a halogen lamp and interference filter was deployed in some malaria-endemic countries. However, it has not been widely adopted because: (1) the lamp was weak as an excitation light and the set-up did not work well under unstable power supply; and, (2) the staining of samples was frequently inconsistent. METHODS: The halogen lamp was replaced by a low-cost, blue light-emitting diode (LED) lamp...
February 7, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29413959/role-of-gut-microbiota-and-oxidative-stress-in-the-progression-of-non-alcoholic-fatty-liver-disease-to-hepatocarcinoma-current-and-innovative-therapeutic-approaches
#12
REVIEW
Antonella Borrelli, Patrizia Bonelli, Franca Maria Tuccillo, Ira D Goldfine, Joseph L Evans, Franco Maria Buonaguro, Aldo Mancini
Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in industrialized countries. NAFLD progresses through the inflammatory phase of non-alcoholic steatohepatitis (NASH) to fibrosis and cirrhosis, with some cases developing liver failure or hepatocellular carcinoma (HCC). Liver biopsy remains the gold standard approach to a definitive diagnosis of NAFLD and the distinction between simple steatosis and NASH. The pathogenesis of NASH is still not clear. Several theories have been proposed ranging from the "Two Hit Theory" to the "Multiple Hit Theory"...
January 27, 2018: Redox Biology
https://www.readbyqxmd.com/read/29411133/multicenter-review-of-robotic-versus-laparoscopic-ventral-hernia-repair-is-there-a-role-for-robotics
#13
Peter A Walker, Audriene C May, Jiandi Mo, Deepa V Cherla, Monica Rosales Santillan, Steven Kim, Heidi Ryan, Shinil K Shah, Erik B Wilson, Shawn Tsuda
BACKGROUND: The utilization of robotic platforms for general surgery procedures such as hernia repair is growing rapidly in the United States. A limited amount of data are available evaluating operative outcomes in comparison to standard laparoscopic surgery. We completed a retrospective review comparing robotic and laparoscopic ventral hernia repair to provide safety and outcomes data to help design a future prospective trial design. METHODS: A retrospective review of 215 patients undergoing ventral hernia repair (142 robotic and 73 laparoscopic) was completed at two large academic centers...
February 6, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29410789/fine-scale-movement-responses-of-free-ranging-harbour-porpoises-to-capture-tagging-and-short-term-noise-pulses-from-a-single-airgun
#14
Floris M van Beest, Jonas Teilmann, Line Hermannsen, Anders Galatius, Lonnie Mikkelsen, Signe Sveegaard, Jeppe Dalgaard Balle, Rune Dietz, Jacob Nabe-Nielsen
Knowledge about the impact of anthropogenic disturbances on the behavioural responses of cetaceans is constrained by lack of data on fine-scale movements of individuals. We equipped five free-ranging harbour porpoises (Phocoena phocoena) with high-resolution location and dive loggers and exposed them to a single 10 inch3 underwater airgun producing high-intensity noise pulses (2-3 s intervals) for 1 min. All five porpoises responded to capture and tagging with longer, faster and more directed movements as well as with shorter, shallower, less wiggly dives immediately after release, with natural behaviour resumed in less than or equal to 24 h...
January 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29402288/trends-in-parasite-prevalence-following-13%C3%A2-years-of-malaria-interventions-on-bioko-island-equatorial-guinea-2004-2016
#15
Jackie Cook, Dianna Hergott, Wonder Phiri, Matilde Riloha Rivas, John Bradley, Luis Segura, Guillermo Garcia, Chris Schwabe, Immo Kleinschmidt
BACKGROUND: Whilst there have been substantial reductions in malaria transmission over the past decade, in many countries in West and Central Africa the malaria burden remains high. Monitoring and evaluation of malaria transmission trends and intervention strategies are key elements for malaria control programmes. This study uses a time series of annual malaria indicator surveys to track the progress of malaria control in Bioko Island, Equatorial Guinea, over a 13 year period of intensive interventions...
February 5, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29401707/in-vivo-evaluation-of-3d-printed-polycaprolactone-scaffold-implantation-combined-with-%C3%AE-tcp-powder-for-alveolar-bone-augmentation-in-a-beagle-defect-model
#16
Su A Park, Hyo-Jung Lee, Keun-Suh Kim, Sang Jin Lee, Jung-Tae Lee, Sung-Yeol Kim, Na-Hee Chang, Shin-Young Park
Insufficient bone volume is one of the major challenges encountered by dentists after dental implant placement. This study aimed to evaluate the efficacy of a customized three-dimensional polycaprolactone (3D PCL) scaffold implant fabricated with a 3D bio-printing system to facilitate rapid alveolar bone regeneration. Saddle-type bone defects were surgically created on the healed site after extracting premolars from the mandibles of four beagle dogs. The defects were radiologically examined using computed tomography for designing a customized 3D PCL scaffold block to fit the defect site...
February 4, 2018: Materials
https://www.readbyqxmd.com/read/29401018/innovative-use-of-electronic-consultations-in-preoperative-anesthesiology-evaluation-at-va-medical-centers-in-new-england
#17
Melissa K Afable, Gouri Gupte, Steven R Simon, Jessica Shanahan, Varsha Vimalananda, Eun Ji Kim, Judith Strymish, Jay D Orlander
Electronic consultations (e-consults) improve access to specialty care without requiring face-to-face patient visits. We conducted a mixed-methods descriptive study to understand the variability in e-consult use across anesthesiology departments in the Veterans Affairs New England Healthcare System (VANEHS). In the period 2012-15, the system experienced a rapid increase in the use of anesthesiology e-consults: 5,023 were sent in 2015, compared with 103 in 2012. Uptake across sites varied from near-universal use of e-consults for preoperative assessment to use for only selected low-risk patients or no use...
February 2018: Health Affairs
https://www.readbyqxmd.com/read/29399263/three-day-field-treatment-with-ingenol-disoxate-leo-43204-for-actinic-keratosis-a-phase-ii-trial
#18
Daniel M Siegel, Stephen Tyring, Walter K Nahm, Marie Louise Østerdal, Astrid H Petersen, Brian Berman
OBJECTIVE: The purpose of this study was to evaluate the safety and efficacy of ingenol disoxate gel using a once-daily, three-day field treatment regimen in patients with actinic keratosis. DESIGN: This was a Phase II, multicenter, open-label trial (clinicaltrials.gov: NCT02305888). SETTING: The study was conducted in 20 trial sites in the United States. PARTICIPANTS: Participants included patients with 5 to 20 clinically typical actinic keratosis lesions on the full face/chest (250cm2), scalp (25-250cm2), or the trunk/extremities (250cm2)...
December 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29397224/evidence-of-the-impact-of-monovalent-rotavirus-vaccine-on-childhood-acute-gastroenteritis-hospitalization-in-togo
#19
Enyonam Tsolenyanu, Koffi E Djadou, Mawouto Fiawoo, Djatougbe A E Akolly, Jason M Mwenda, Eyal Leshem, Jacqueline E Tate, Negar Aliabadi, Winiga Koudema, Koffi M Guedenon, Mawussi Godonou, Anoumou Dagnra, Adama D Gbadoe, Amevegbe Boko, Dadja Landoh, Yawo Atakouma, Umesh D Parashar
BACKGROUND: Monovalent rotavirus vaccine (RV1) was introduced in the immunization schedule of Togo in June 2014. We evaluated the impact of rotavirus vaccines on acute gastroenteritis (AGE) and rotavirus-associated hospitalizations in Togolese children. METHODS: Sentinel surveillance for AGE (defined as ≥3 liquid or semi-liquid stools/24 h lasting <7 days) hospitalizations among children <5 years of age was conducted in two sites in the capital city, Lome...
January 31, 2018: Vaccine
https://www.readbyqxmd.com/read/29388188/the-paracelsus-score-a-novel-diagnostic-tool-for-pyoderma-gangrenosum
#20
F Jockenhöfer, U Wollina, K A Salva, S Benson, J Dissemond
BACKGROUND: The lack of objective diagnostic criteria renders pyoderma gangrenosum (PG) a diagnosis of exclusion. The diagnostic approaches proposed to date have not been systematically evaluated. Thus, PG remains a challenging and frequently misdiagnosed disorder. OBJECTIVES: To develop and assess a comprehensive yet clinically practicable as well as sensitive diagnostic scoring system for PG. METHODS: Clinical history and images of a total of 60 subjects with previously confirmed PG located on the lower extremity as well as a control cohort of 50 patients with venous leg ulcers were retrospectively evaluated by expert teams at two tertiary dermatological centres specializing in wound care using a newly developed diagnostic scoring system composed of ten criteria...
February 1, 2018: British Journal of Dermatology
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