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https://www.readbyqxmd.com/read/29414264/risk-stratification-for-sudden-cardiac-death-after-myocardial-infarction
#1
Jonathan W Waks, Alfred E Buxton
Sudden cardiac death (SCD) accounts for ∼50% of mortality after myocardial infarction (MI). Most SCDs result from ventricular tachyarrhythmias, and the tachycardias that precipitate cardiac arrest result from multiple mechanisms. As a result, it is highly unlikely that any single test will identify all patients at risk for SCD. Current guidelines for use of implantable cardioverter-defibrillators (ICDs) to prevent SCD are based primarily on measurement of left ventricular ejection fraction (LVEF). Although reduced LVEF is associated with increased total cardiac mortality after MI, the focus of current guidelines on LVEF omits ∼50% of patients who die suddenly...
January 29, 2018: Annual Review of Medicine
https://www.readbyqxmd.com/read/29344960/association-of-genetic-variation-in-telomere-related-snp-and-telomerase-with-ventricular-arrhythmias-in-ischaemic-cardiomyopathy
#2
Vinit Sawhney, Scott Brouilette, Niall Campbell, Steven Coppen, Victoria Baker, Ross Hunter, Mehul Dhinoja, Atholl Johnston, Mark Earley, Simon Sporton, Ken Suzuki, Richard Schilling
BACKGROUND: Telomeres are known to provide genomic stability and telomere length has been associated with cardiovascular diseases. Moreover, a higher telomerase activity has been shown to be associated with ventricular arrhythmias (VA) in ischaemic cardiomyopathy. Increasing evidence suggests that genetic variation in key telomere genes has an impact on telomerase activity. Each copy of the minor allele of SNP rs12696304, at a locus including TERC (telomerase) has been associated with ∼ 75 bp reduction in mean telomere length likely mediated by an effect on TERC expression...
January 17, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29146417/association-between-percutaneous-hemodynamic-support-device-and-survival-from-cardiac-arrest-in-the-state-of-michigan
#3
Andrew Pressman, Kelly N Sawyer, William Devlin, Robert Swor
INTRODUCTION: The role of circulatory support in the post-cardiac arrest period remains controversial. Our objective was to investigate the association between treatment with a percutaneous hemodynamic support device and outcome after admission for cardiac arrest. METHODS: We performed a retrospective study of adult patients with admission diagnosis of cardiac arrest or ventricular fibrillation (VF) from the Michigan Inpatient Database, treated between July 1, 2010, and June 30, 2013...
October 17, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28950317/the-association-of-depression-at-any-time-to-the-risk-of-death-following-coronary-artery-disease-diagnosis
#4
Heidi T May, Benjamin D Horne, Stacey Knight, Kirk U Knowlton, Tami L Bair, Donald L Lappé, Viet T Le, Joseph B Muhlestein
Aims: Depression is a risk factor for cardiovascular (CV) diseases, incident CV events, and mortality. Among individuals who experience a CV diagnosis or event, whether a subsequent diagnosis of depression is associated with a greater risk of mortality is unknown. Among patients with existing coronary artery disease (CAD), this study evaluated the association of a subsequent depression diagnosis with all-cause mortality. Methods and Results: Patients (N = 24,137) who had angiographically determined CAD (stenosis ≥70%) were studied...
July 26, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/28687707/validity-of-cardiovascular-data-from-electronic-sources-the-multi-ethnic-study-of-atherosclerosis-and-healthlnk
#5
Faraz S Ahmad, Cheeling Chan, Marc B Rosenman, Wendy S Post, Daniel G Fort, Philip Greenland, Kiang J Liu, Abel N Kho, Norrina B Allen
BACKGROUND: Understanding the validity of data from electronic data research networks is critical to national research initiatives and learning healthcare systems for cardiovascular care. Our goal was to evaluate the degree of agreement of electronic data research networks in comparison with data collected by standardized research approaches in a cohort study. METHODS: We linked individual-level data from MESA (Multi-Ethnic Study of Atherosclerosis), a community-based cohort, with HealthLNK, a 2006 to 2012 database of electronic health records from 6 Chicago health systems...
September 26, 2017: Circulation
https://www.readbyqxmd.com/read/28679419/improvement-of-left-ventricular-ejection-fraction-in-revascularized-postmyocardial-patients-indication-for-statistical-fallacy
#6
Rona Reibis, Annett Salzwedel, Klaus Bonaventura, Heinz Völler, Karl Wegscheider
BACKGROUND: Reduced left ventricular ejection fraction (LVEF) ≤30% is the most powerful prognostic indicator for sudden cardiac death (SCD) in patients after myocardial infarction (MI), but there are little data about long-term changes of LVEF after revascularization and the following implantation of a cardioverter defibrillator (ICD). METHODS: We performed a retrospective analysis of 277 patients with reduced LVEF at least 1 month after MI and complete revascularization...
July 5, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28494900/perioperative-strokes-after-coronary-artery-bypass-grafting-with-staged-carotid-endarterectomy-a-nationwide-perspective
#7
Hannah Cheng, Reshmi Udesh, Amol Mehta, Parthasarathy D Thirumala
STUDY OBJECTIVE: To examine the risk of perioperative stroke on in-hospital morbidity and mortality in staged coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) procedures. DESIGN: The National Inpatient Sample (NIS) database was used to extract data on all patients who underwent staged CABG CEA procedures. They were identified using the ICD-9 (International Classification of Diseases, Ninth Revision-Clinical Modification) diagnosis and procedure codes...
June 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28431133/prediction-of-sudden-and-non-sudden-cardiac-death-in-post-infarction-patients-with-reduced-left-ventricular-ejection-fraction-by-periodic-repolarization-dynamics-madit-ii-substudy
#8
Konstantinos D Rizas, Scott McNitt, Wolfgang Hamm, Steffen Massberg, Stefan Kääb, Wojciech Zareba, Jean-Philippe Couderc, Axel Bauer
Aims: To test the value of Periodic Repolarization Dynamics (PRD), a recently validated electrocardiographic marker of sympathetic activity, as a novel approach to predict sudden cardiac death (SCD) and non-sudden cardiac death (N-SCD) and to improve identification of patients that profit from ICD-implantation. Methods and results: We included 856 post-infarction patients with left-ventricular ejection fraction (LVEF) ≤30% of the MADIT-II trial in sinus rhythm...
July 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28343763/temporary-removal-identifying-high-risk-post-infarction-patients-by-autonomic-testing-below-the-tip-of-the-iceberg
#9
Axel Bauer
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
March 18, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27881561/reassessment-of-cardiac-function-and-implantable-cardioverter-defibrillator-use-among-medicare-patients-with-low-ejection-fraction-after-myocardial-infarction
#10
Sean D Pokorney, Amy L Miller, Anita Y Chen, Laine Thomas, Gregg C Fonarow, James A de Lemos, Sana M Al-Khatib, Eric J Velazquez, Eric D Peterson, Tracy Y Wang
BACKGROUND: Guidelines recommend that patients with low ejection fraction (EF) after myocardial infarction (MI) have their EF reassessed 40 days after MI for implantable cardioverter-defibrillator (ICD) candidacy. This study examines rates of EF reassessment and their association with 1-year ICD implantation in post-MI patients with low EF. METHODS: We examined rates of postdischarge EF reassessment and ICD implantation among 10 289 Medicare-insured patients ≥65 years of age with an EF≤35% during the index MI admission from January 2007 through September 2010 in ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry(-)Get With The Guidelines)...
January 3, 2017: Circulation
https://www.readbyqxmd.com/read/27567235/differential-trends-in-myocardial-infarction-mortality-over-1975-2010-in-france-according-to-gender-an-age-period-cohort-analysis
#11
A Gabet, E Chatignoux, P Ducimetière, N Danchin, V Olié
BACKGROUND: A dramatic reduction in mortality from myocardial infarction (MI) has been observed in France as in other western countries. The dynamics of this decline are likely to have differed according to age and sex. Our study sought to clarify the contributions of age, period and birth-cohort effects on post-MI mortality in France between 1975 and 2010 and to identify gender-specific trends. METHODS: Trends were analysed using an age-period-cohort (APC) model...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27521819/the-impact-of-surgical-care-improvement-project-measures-on-in-hospital-outcomes-following-elective-vascular-procedures
#12
COMPARATIVE STUDY
Kenneth R Nakazawa, Natalia N Egorova, John R Power, Peter L Faries, Ageliki G Vouyouka
BACKGROUND: As part of the Surgical Care Improvement Project (SCIP), a national quality partnership of organizations including the Centers for Medicare and Medicaid Services and the Centers for Disease Control and Prevention implemented several perioperative guidelines regarding antibiotic, venous thromboembolism (VTE), and beta-blocker prophylaxis for surgical patients. We evaluated the effect of SCIP on in-hospital surgical site infections (SSI), graft infections, VTE, myocardial infarctions (MIs), cardiac complications, mortality, and length of stay following elective major vascular surgery...
January 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27307250/dialysis-requirement-long-term-major-adverse-cardiovascular-events-mace-and-all-cause-mortality-in-hospital-acquired-acute-kidney-injury-aki-a-propensity-matched-cohort-study
#13
Bolanle A Omotoso, Emaad M Abdel-Rahman, Wenjun Xin, Jennie Z Ma, Kenneth W Scully, Fatiu A Arogundade, Rasheed A Balogun
BACKGROUND: Dialysis-requiring acute kidney injury (D-AKI) is common in hospitalized patients. Many patients survive the immediate post AKI period, thus at risk of suffering long-term sequelae of AKI. Prior studies examining long term outcomes lack non-dialyzed AKI control groups. Without non-dialyzed AKI control group, these studies cannot provide relevant information on long-term risks or benefits associated with dialysis intervention following AKI. METHODS: The study cohort comprises of adults admitted to the University of Virginia Medical Center between January 1, 2002 and December 31, 2012 with baseline eGFR ≥60 ml/min per 1...
December 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/26969220/catheter-ablation-of-ischemic-ventricular-tachycardia-with-remote-magnetic-navigation-stop-vt-multicenter-trial
#14
MULTICENTER STUDY
Jan Skoda, Arash Arya, Fermin Garcia, Edward Gerstenfeld, Francis Marchlinski, Gerhard Hindricks, John Miller, Jan Petru, Lucie Sediva, Qun Sha, Marek Janotka, Milan Chovanec, Petr Waldauf, Petr Neuzil, Vivek Y Reddy
INTRODUCTION: Catheter ablation is an effective treatment of scar-related ventricular tachycardia (VT), but the overall complexity of the procedure has precluded its widespread use. Remote magnetic navigation (RMN) has been shown to facilitate cardiac mapping and ablation of VT in a retrospective series. STOP-VT is the first multicenter, prospective, single-arm and single-procedure study evaluating RMN-based mapping and ablation of post-infarction VT. METHODS: Patients with documented VT and prior MI, in whom an ICD was implanted either for primary or secondary prevention, were recruited from four EU and US centers...
March 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/26796195/long-term-outcomes-in-survivors-of-early-ventricular-arrhythmias-after-acute-st-elevation-and-non-st-elevation-myocardial-infarction-treated-with-percutaneous-coronary-intervention
#15
Jackson J Liang, Erin A Fender, Yong-Mei Cha, Ryan J Lennon, Abhiram Prasad, Gregory W Barsness
Guidelines do not recommend an implantable cardioverter defibrillator (ICD) for prevention of sudden death in patients who develop ventricular arrhythmia (VA) within 48 hours of acute myocardial infarction (AMI) if they are successfully revascularized. We aimed to determine long-term survival in a cohort of early VA survivors treated with percutaneous coronary intervention (PCI) and to determine whether certain high-risk characteristics predicted worse outcomes. This retrospective study included all patients with early VA after AMI treated with PCI at our institution from 2002 to 2012 who survived to hospital discharge...
March 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26664773/role-of-123-i-iobenguane-myocardial-scintigraphy-in-predicting-short-term-left-ventricular-functional-recovery-an-interesting-image
#16
Mauro Feola, Stephane Chauvie, Alberto Biggi, Marzia Testa
(123)I-iobenguane myocardial scintigraphy (MIBG) has been shown to be a predictor of sudden cardiac mortality in patients with heart failure. One patient with recent anterior myocardial infarction (MI) treated with coronary angioplasty and having left ventricular ejection fraction (LVEF) of 30% underwent early MIBG myocardial scintigraphy/tetrofosmin single-photon emission computed tomography (SPECT) in order to help evaluate his eligibility for implantable cardioverter defibrillator (ICD). The late heart/mediastinum (H/M) ratio was calculated to be 1...
2015: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/26345262/comparison-of-patient-and-partner-quality-of-life-and-health-outcomes-in-the-first-year-after-an-implantable-cardioverter-defibrillator-icd
#17
RANDOMIZED CONTROLLED TRIAL
Cynthia M Dougherty, Allison M Fairbanks, Linda H Eaton, Megan L Morrison, Mi Sun Kim, Elaine A Thompson
Recovery following an implantable cardioverter defibrillator (ICD) impacts both the patient and partner, often in divergent ways. Patients may have had a cardiac arrest or cardiac arrhythmias, whereas partners may have to perform CPR and manage the ongoing challenges of heart disease therapy. Currently, support for post-ICD care focuses primarily on restoring patient functioning with few interventions available to partners who serve as primary support. This descriptive study examined and compared patterns of change for both patients and partners during the first year post-ICD implantation...
February 2016: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/26289034/the-effect-of-elapsed-time-from-myocardial-infarction-on-mortality-and-major-adverse-cardiac-and-cerebrovascular-events-in-icd-patients
#18
Lidia R Bons, Lara Dabiri-Abkenari, Ron T VAN Domburg, Tamas Szili-Torok, Felix Zijlstra, Dominic A M J Theuns
BACKGROUND: Despite the effectiveness of implantable cardioverter defibrillator (ICD) therapy in reducing mortality, the optimal timing of ICD implantation after myocardial infarction (MI) remains inconclusive. The aim of this study is to evaluate the association of elapsed time from MI to ICD implantation on mortality and major adverse cardiac and cerebrovascular events (MACCEs) in patients with prior MI. METHODS: We studied 974 patients who underwent a first ICD implantation between October 1998 and August 2011...
December 2015: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/26210409/selvester-scoring-in-patients-with-strict-lbbb-using-the-quaress-software
#19
Xiaojuan Xia, Uzma Chaudhry, Björn Wieslander, Rasmus Borgquist, Galen S Wagner, David G Strauss, Pyotr Platonov, Martin Ugander, Jean-Philippe Couderc
BACKGROUND: Estimation of the infarct size from body-surface ECGs in post-myocardial infarction patients has become possible using the Selvester scoring method. Automation of this scoring has been proposed in order to speed-up the measurement of the score and improving the inter-observer variability in computing a score that requires strong expertise in electrocardiography. In this work, we evaluated the quality of the QuAReSS software for delivering correct Selvester scoring in a set of standard 12-lead ECGs...
September 2015: Journal of Electrocardiology
https://www.readbyqxmd.com/read/26103027/implantable-cardioverter-defibrillator-use-among-medicare-patients-with-low-ejection-fraction-after-acute-myocardial-infarction
#20
Sean D Pokorney, Amy L Miller, Anita Y Chen, Laine Thomas, Gregg C Fonarow, James A de Lemos, Sana M Al-Khatib, Eric D Peterson, Tracy Y Wang
IMPORTANCE: Implantable cardioverter-defibrillators (ICDs) are not recommended within 40 days of myocardial infarction (MI); thus, ICD implantation might not be considered during the post-MI care transition. OBJECTIVE: To examine ICD implantation rates and associated mortality among older MI patients with low ejection fraction (EF). DESIGN, SETTING, AND PARTICIPANTS: Retrospective observational study of Medicare beneficiaries with an EF of 35% or less after MI, treated at 441 US hospitals between 2007 and 2010, excluding patients with prior ICD implantation...
June 23, 2015: JAMA: the Journal of the American Medical Association
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