Giovanni Boscarino, Viviana Cardilli, Maria Giulia Conti, Federica Liguori, Paola Repole, Pasquale Parisi, Gianluca Terrin
INTRODUCTION: Prolonged mechanical ventilation, commonly used to assist preterm newborns, increases the risk of developing bronchopulmonary dysplasia (BPD). In recent decades, studies have demonstrated that systemic corticosteroids play a significant role in the prevention and management of BPD. In this systematic review of randomized controlled trials (RCTs), we evaluated the association between the administration of systemic corticosteroids in preterm infants and its long-term outcomes, such as neurodevelopment, growth, extubation rate, and related adverse effects...
2024: Frontiers in Pediatrics